Medical College of Wisconsin
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Routine screening for psychosocial distress following hematopoietic stem cell transplantation. Bone Marrow Transplant 2005 Jan;35(1):77-83 PMID: 15502851

Pubmed ID



The diagnosis and treatment of cancer is often associated with high levels of psychosocial distress, yet exploration of these issues is rarely included in routine oncologic care. We conducted a pilot study to evaluate the feasibility of screening for psychosocial distress after autologous and allogeneic stem cell transplantation. A total of 80 adults were enrolled in Boston, MA, USA. Subjects completed self-administered assessments prior to hospital admission, at their first clinic visit after hospital discharge, and at 100 days post transplant. Assessments included validated instruments assessing psychosocial distress and quality of life (QOL). Elevated levels of anxiety and/or depression were detected in 55% of those providing pre-transplant assessments and were associated with compromised QOL. Post transplant screening was successfully performed in 69% of subjects and identified that 44% had symptoms of depression, anxiety or post traumatic stress disorder. Pre-transplant distress was associated with detection of distress after transplantation (81 vs 13%, P< 0.0001). In summary, we detected high levels of distress in transplant patients using self-administered tools. Pre-transplant distress appears to be highly predictive of distress post transplant and is a feasible marker to target screening and intervention programs.

Author List

Lee SJ, Loberiza FR, Antin JH, Kirkpatrick T, Prokop L, Alyea EP, Cutler C, Ho VT, Richardson PG, Schlossman RL, Fisher DC, Logan B, Soiffer RJ


Brent R. Logan PhD Director, Professor in the Institute for Health and Equity department at Medical College of Wisconsin


2-s2.0-19944429515   75 Citations

MESH terms used to index this publication - Major topics in bold

Adaptation, Psychological
Hematopoietic Stem Cell Transplantation
Life Change Events
Mass Screening
Middle Aged
Pilot Projects
Quality of Life
Sick Role
Stem Cell Transplantation
Stress Disorders, Post-Traumatic
Stress, Psychological
Surveys and Questionnaires
Time Factors
jenkins-FCD Prod-296 4db9d02597e0a2e889e230f853b641c12f1c3ee3