Upregulation of specific mRNA levels in rat brain after cell phone exposure. Electromagn Biol Med 2008;27(2):147-54
Date
06/24/2008Pubmed ID
18568932DOI
10.1080/15368370802072208Scopus ID
2-s2.0-46249127814 (requires institutional sign-in at Scopus site) 17 CitationsAbstract
Adult Sprague-Dawley rats were exposed to regular cell phones for 6 h per day for 126 days (18 weeks). RT-PCR was used to investigate the changes in levels of mRNA synthesis of several injury-associated proteins. Calcium ATPase, Neural Cell Adhesion Molecule, Neural Growth Factor, and Vascular Endothelial Growth Factor were evaluated. The results showed statistically significant mRNA up-regulation of these proteins in the brains of rats exposed to cell phone radiation. These results indicate that relative chronic exposure to cell phone microwave radiation may result in cumulative injuries that could eventually lead to clinically significant neurological damage.
Author List
Yan JG, Agresti M, Zhang LL, Yan Y, Matloub HSAuthor
Hani S. Matloub MD Professor in the Plastic Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsBrain
Cell Phone
Dose-Response Relationship, Radiation
Environmental Exposure
Female
Microwaves
Nerve Tissue Proteins
RNA, Messenger
Radiation Dosage
Rats
Rats, Sprague-Dawley
Up-Regulation
