Faculty Collaboration Database

Focal hepatic masses and fatty infiltration detected by enhanced dynamic CT. Radiology 1986 Jan;158(1):45-9

Date

01/01/1986

Pubmed ID

3940396

DOI

10.1148/radiology.158.1.3940396

Scopus ID

2-s2.0-0022656567 (requires institutional sign-in at Scopus site)   68 Citations

Abstract

A prospective evaluation of 185 consecutive patients with abdominal pain or suspected hepatic malignancy was performed to compare the diagnostic accuracy of contrast material-enhanced incremental dynamic computed tomography (IDCT) scans with plain CT scans for detection of hepatic masses and fatty infiltration of the liver. After a series of nondynamic plain CT scans, patients were examined at 7.5 scans/min during intravenous injection of 50 g of iodinated contrast material. Enhanced IDCT study was found to be an accurate, reproducible technique for liver evaluation. Of 155 neoplasms measured in 59 patients, liver-to-lesion differences of less than 10 HU were seen in only two tumors in IDCT scans as compared with 31 in plain CT scans. These differences were not significantly affected by lesion size for neoplasms greater than 6 mm in diameter. A confident diagnosis of fatty infiltration (23 patients) could be made when the spleen-minus-liver difference was 25 HU on enhanced IDCT scans and 10 HU on plain CT scans. In eight patients with liver metastases, there was little variation in the attenuation values of normal-appearing liver between serial examination studies (8 HU average).

Author List

Alpern MB, Lawson TL, Foley WD, Perlman SJ, Reif LJ, Arevalos E, Rimm AA

MESH terms used to index this publication - Major topics in bold

Contrast Media
Fatty Liver
Humans
Liver Neoplasms
Radiographic Image Enhancement
Tomography, X-Ray Computed