Medical College of Wisconsin
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The role of registries in facilitating clinical research in BMT: examples from the Center for International Blood and Marrow Transplant Research. Bone Marrow Transplant 2008 Aug;42 Suppl 1:S1-S2 PMID: 18724277

Pubmed ID





Observational databases, such as those maintained by the Center for International Blood and Marrow Transplant Research (CIBMTR) and the European Blood and Marrow Transplant Group (EBMT), play an important role in facilitating research into hematopoietic SCT (HCT) outcomes. The CIBMTR maintains a large database of the outcome of BMTs performed in 450 centers in 47 countries, including information on 240,000 transplant recipients and adding information on about 14,000 new transplants per year. The database has data for 9000 survivors followed for 10 or more years. The database may facilitate the understanding of outcomes by addressing questions difficult to answer through clinical trials. Clinical databases may also aid the development of optimal designs for prospective clinical trials. Use of the CIBMTR database for trial design and monitoring is an integral part of the US Blood and Marrow Transplant Clinical Trials Network (BMT CTN). The establishment of international outcomes registries was an important component of advances in HCT over the past three decades. Future progress will be further enhanced by inter-registry collaboration through the Worldwide Blood and Marrow Transplant Group (WBMT).

Author List

Horowitz M


Mary M. Horowitz MD, MS Center Director, Professor in the Medicine department at Medical College of Wisconsin


2-s2.0-50549094738   38 Citations

MESH terms used to index this publication - Major topics in bold

Bone Marrow Transplantation
Databases as Topic
Hematopoietic Stem Cell Transplantation
jenkins-FCD Prod-331 a335b1a6d1e9c32173c9534e6f6ff51494143916