2 | Modulatory effects of estrous cycle on ingestive behaviors and energy balance in young adult C57BL/6J mice maintained on a phytoestrogen-free diet. (Reho JJ, Muskus PC, Bennett DM, Grobe CC, Burnett CML, Nakagawa P, Segar JL, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2024 Mar 01;326(3):R242-R253 |
1 | Deletion of Vβ3+CD4+ T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8+ T cells. (Ye C, Clements SA, Gu W, Geurts AM, Mathews CE, Serreze DV, Chen YG, Driver JP) Proc Natl Acad Sci U S A 2023 Dec 05;120(49):e2312039120 |
4 | Early-life sodium deprivation programs long-term changes in ingestive behaviors and energy expenditure in C57BL/6J mice. (Ziegler AA, Lawton SBR, Grobe CC, Reho JJ, Freudinger BP, Burnett CML, Nakagawa P, Grobe JL, Segar JL) Am J Physiol Regul Integr Comp Physiol 2023 Nov 01;325(5):R576-R592 |
3 | Intracellular tPA-PAI-1 interaction determines VLDL assembly in hepatocytes. (Dai W, Zhang H, Lund H, Zhang Z, Castleberry M, Rodriguez M, Kuriakose G, Gupta S, Lewandowska M, Powers HR, Valmiki S, Zhu J, Shapiro AD, Hussain MM, López JA, Sorci-Thomas MG, Silverstein RL, Ginsberg HN, Sahoo D, Tabas I, Zheng Z) Science 2023 Sep;381(6661):eadh5207 5 Citations |
1 | Δ9 -Tetrahydrocannabinol self-administration induces cell type-specific adaptations in the nucleus accumbens core. (Garcia-Keller C, Hohmeister M, Seidling K, Beloate L, Chioma V, Spencer S, Kalivas P, Neuhofer D) Addict Biol 2023 Aug;28(8):e13286 2 Citations |
5 | Cardiometabolic Effects of DOCA-Salt in Mice Depend on Ambient Temperature. (Grobe CC, Reho JJ, Brown-Williams D, Ziegler AA, Mathieu NM, Lawton SBR, Fekete EM, Brozoski DT, Wackman KK, Burnett CML, Nakagawa P, Sigmund CD, Segar JL, Grobe JL) Hypertension 2023 Sep;80(9):1871-1880 |
1 | Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection. (Wills BM, Garai P, Riegert MO, Sanchez FT, Pickrum AM, Frank DW, Brockman KL) Infect Immun 2023 Jul 18;91(7):e0003723 3 Citations |
1 | Epidermal Growth Factor Receptor in Hepatic Endothelial Cells Suppresses MCP-1-Dependent Monocyte Recruitment in Diabetes. (Zhang X, Ohayon-Steckel L, Coppin E, Johny E, Dasari A, Florentin J, Vasamsetti S, Dutta P) J Immunol 2023 May 01;210(9):1363-1371 |
1 | Lymphocytic Choriomeningitis Virus Clone 13 Infection Results in CD8 T Cell-Mediated Host Mortality in Diacylglycerol Kinase α-Deficient Mice. (Kudek MR, Xin G, Alson D, Holzhauer S, Shen J, Kasmani MY, Riese M, Cui W) J Immunol 2023 May 01;210(9):1281-1291 |
2 | Cardiomyocyte ploidy is dynamic during postnatal development and varies across genetic backgrounds. (Swift SK, Purdy AL, Kolell ME, Andresen KG, Lahue C, Buddell T, Akins KA, Rau CD, O'Meara CC, Patterson M) Development 2023 Apr 01;150(7) 8 Citations |
1 | CD47-SIRPα axis blockade in NASH promotes necroptotic hepatocyte clearance by liver macrophages and decreases hepatic fibrosis. (Shi H, Wang X, Li F, Gerlach BD, Yurdagul A Jr, Moore MP, Zeldin S, Zhang H, Cai B, Zheng Z, Valenti L, Tabas I) Sci Transl Med 2022 Nov 23;14(672):eabp8309 16 Citations |
2 | T cell-extrinsic IL-1 signaling controls long-term gammaherpesvirus infection by suppressing viral reactivation. (Sylvester PA, Corbett JA, Tarakanova VL) Virology 2022 Nov;576:134-140 1 Citation |
5 | ARRB2 (β-Arrestin-2) Deficiency Alters Fluid Homeostasis and Blood Pressure Regulation. (Mathieu NM, Nakagawa P, Grobe CC, Reho JJ, Brozoski DT, Lu KT, Wackman KK, Ritter ML, Segar JL, Grobe JL, Sigmund CD) Hypertension 2022 Nov;79(11):2480-2492 4 Citations |
1 | The Antagonism between the Murine Gammaherpesvirus Protein Kinase and Global Interferon Regulatory Factor 1 Expression Shapes the Establishment of Chronic Infection. (Jondle CN, Sylvester PA, Schmalzriedt DL, Njoya K, Tarakanova VL) J Virol 2022 Oct 26;96(20):e0126022 1 Citation |
1 | T Cell-Specific STAT1 Expression Promotes Lytic Replication and Supports the Establishment of Gammaherpesvirus Latent Reservoir in Splenic B Cells. (Sylvester PA, Jondle CN, Schmalzriedt DL, Dittel BN, Tarakanova VL) mBio 2022 Aug 30;13(4):e0210722 1 Citation |
5 | Chronic intracerebroventricular infusion of angiotensin II causes dose- and sex-dependent effects on intake behaviors and energy homeostasis in C57BL/6J mice. (Oliveira V, Reho JJ, Balapattabi K, Ritter ML, Mathieu NM, Opichka MA, Lu KT, Grobe CC, Silva SD Jr, Wackman KK, Nakagawa P, Segar JL, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2022 Oct 01;323(4):R410-R421 4 Citations |
1 | T Cell-Intrinsic Interleukin 17 Receptor A Signaling Supports the Establishment of Chronic Murine Gammaherpesvirus 68 Infection. (Jondle CN, Tarakanova VL) J Virol 2022 Jul 27;96(14):e0063922 2 Citations |
1 | Variation in blood microbial lipopolysaccharide (LPS) contributes to immune reconstitution in response to suppressive antiretroviral therapy in HIV. (Luo Z, Health SL, Li M, Yang H, Wu Y, Collins M, Deeks SG, Martin JN, Scott A, Jiang W) EBioMedicine 2022 Jun;80:104037 12 Citations |
1 | Extracellular matrix metalloproteinase-9 (MMP-9) is required in female mice for 17β-estradiol enhancement of hippocampal memory consolidation. (Gross KS, Lincoln CM, Anderson MM, Geiger GE, Frick KM) Psychoneuroendocrinology 2022 Jul;141:105773 2 Citations |
10 | Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet. (Patil CN, Ritter ML, Wackman KK, Oliveira V, Balapattabi K, Grobe CC, Brozoski DT, Reho JJ, Nakagawa P, Mouradian GC Jr, Kriegel AJ, Kwitek AE, Hodges MR, Segar JL, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2022 Jun 01;322(6):R467-R485 6 Citations |
1 | Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition. (Liu D, Nanclares C, Simbriger K, Fang K, Lorsung E, Le N, Amorim IS, Chalkiadaki K, Pathak SS, Li J, Gewirtz JC, Jin VX, Kofuji P, Araque A, Orr HT, Gkogkas CG, Cao R) Mol Psychiatry 2023 Sep;28(9):3727-3738 11 Citations |
1 | Downregulation of low-density lipoprotein receptor mRNA in lymphatic endothelial cells impairs lymphatic function through changes in intracellular lipids. (Vachon L, Smaani A, Tessier N, Jean G, Demers A, Milasan A, Ardo N, Jarry S, Villeneuve L, Alikashani A, Finherty V, Ruiz M, Sorci-Thomas MG, Mayer G, Martel C) Theranostics 2022;12(3):1440-1458 4 Citations |
1 | Antigen cross-presentation in young tumor-bearing hosts promotes CD8+ T cell terminal differentiation. (Moustaki A, Crawford JC, Alli S, Fan Y, Boi S, Zamora AE, McDonald NMN, Wu G, Nakitandwe J, Newman S, Foy S, Silkov A, Thomas PG, Pappo A, Dyer MA, Stewart E, Federico S, Youngblood B) Sci Immunol 2022 Feb 04;7(68):eabf6136 5 Citations |
3 | Nicotinamide Riboside-Conditioned Microbiota Deflects High-Fat Diet-Induced Weight Gain in Mice. (Lozada-Fernández VV, deLeon O, Kellogg SL, Saravia FL, Hadiono MA, Atkinson SN, Grobe JL, Kirby JR) mSystems 2022 Feb 22;7(1):e0023021 10 Citations |
1 | Decorin regulates collagen fibrillogenesis during corneal wound healing in mouse in vivo. (Gupta S, Buyank F, Sinha NR, Grant DG, Sinha PR, Iozzo RV, Chaurasia SS, Mohan RR) Exp Eye Res 2022 Mar;216:108933 13 Citations |
1 | NSAID-Induced Enteropathy Affects Regulation of Hepatic Glucose Production by Decreasing GLP-1 Secretion. (Herz H, Song Y, Ye Y, Tian L, Linden B, Abu El Haija M, Chu Y, Grobe JL, Lengeling RW, Mokadem M) Nutrients 2021 Dec 28;14(1) 3 Citations |
4 | Short-term Housing in Metabolic Caging on Measures of Energy and Fluid Balance in Male C57BL/6J Mice ( Mus musculus). (Ziegler AA, Grobe CC, Reho JJ, Jensen ES, Thulin JD, Segar JL, Grobe JL) J Am Assoc Lab Anim Sci 2022 Mar 01;61(2):132-139 7 Citations |
1 | Myelin-associated glycoprotein activation triggers glutamate uptake by oligodendrocytes in vitro and contributes to ameliorate glutamate-mediated toxicity in vivo. (Vivinetto AL, Castañares C, Garcia-Keller C, Moyano AL, Falcon C, Palandri A, Rozés-Salvador V, Rojas JI, Patrucco L, Monferran C, Cancela L, Cristiano E, Schnaar RL, Lopez PHH) Biochim Biophys Acta Mol Basis Dis 2022 Apr 01;1868(4):166324 1 Citation |
1 | Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice. (Fang K, Liu D, Pathak SS, Yang B, Li J, Karthikeyan R, Chao OY, Yang YM, Jin VX, Cao R) Cells 2021 Nov 26;10(12) 9 Citations |
1 | Adolescent THC Treatment Does Not Potentiate the Behavioral Effects in Adulthood of Maternal Immune Activation. (Stollenwerk TM, Hillard CJ) Cells 2021 Dec 11;10(12) 7 Citations |
2 | Donor T-Cell Repertoire Profiling in Recipient Lymphoid and Parenchyma Organs Reveals GVHD Pathogenesis at Clonal Levels After Bone Marrow Transplantation in Mice. (Wu Y, Fu J, Wang H, Yu XZ) Front Immunol 2021;12:778996 3 Citations |
1 | Neuropilin 1 regulates bone marrow vascular regeneration and hematopoietic reconstitution. (Termini CM, Pang A, Fang T, Roos M, Chang VY, Zhang Y, Setiawan NJ, Signaevskaia L, Li M, Kim MM, Tabibi O, Lin PK, Sasine JP, Chatterjee A, Murali R, Himburg HA, Chute JP) Nat Commun 2021 Nov 30;12(1):6990 13 Citations |
1 | Retinoic Acid Signaling Modulates Recipient Gut Barrier Integrity and Microbiota After Allogeneic Hematopoietic Stem Cell Transplantation in Mice. (Pan P, Atkinson SN, Taylor B, Zhu H, Zhou D, Flejsierowicz P, Wang LS, Morse M, Liu C, Gunsolus IL, Chen X) Front Immunol 2021;12:749002 5 Citations |
1 | (2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice. (Rudin D, McCorvy JD, Glatfelter GC, Luethi D, Szöllősi D, Ljubišić T, Kavanagh PV, Dowling G, Holy M, Jaentsch K, Walther D, Brandt SD, Stockner T, Baumann MH, Halberstadt AL, Sitte HH) Neuropsychopharmacology 2022 Mar;47(4):914-923 9 Citations |
1 | Test-retest reproducibility of in vivo oscillating gradient and microscopic anisotropy diffusion MRI in mice at 9.4 Tesla. (Rahman N, Xu K, Omer M, Budde MD, Brown A, Baron CA) PLoS One 2021;16(11):e0255711 2 Citations |
1 | Tgfβ1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. (Nordquist EM, Dutta P, Kodigepalli KM, Mattern C, McDermott MR, Trask AJ, LaHaye S, Lindner V, Lincoln J) Arterioscler Thromb Vasc Biol 2021 Dec;41(12):2923-2942 4 Citations |
1 | PASTA kinase-dependent control of peptidoglycan synthesis via ReoM is required for cell wall stress responses, cytosolic survival, and virulence in Listeria monocytogenes. (Kelliher JL, Grunenwald CM, Abrahams RR, Daanen ME, Lew CI, Rose WE, Sauer JD) PLoS Pathog 2021 Oct;17(10):e1009881 13 Citations |
5 | Pcpe2, a Novel Extracellular Matrix Protein, Regulates Adipocyte SR-BI-Mediated High-Density Lipoprotein Uptake. (Xu H, Thomas MJ, Kaul S, Kallinger R, Ouweneel AB, Maruko E, Oussaada SM, Jongejan A, Cense HA, Nieuwdorp M, Serlie MJ, Goldberg IJ, Civelek M, Parks BW, Lusis AJ, Knaack D, Schill RL, May SC, Reho JJ, Grobe JL, Gantner B, Sahoo D, Sorci-Thomas MG) Arterioscler Thromb Vasc Biol 2021 Nov;41(11):2708-2725 5 Citations |
1 | Rare and de novo variants in 827 congenital diaphragmatic hernia probands implicate LONP1 as candidate risk gene. (Qiao L, Xu L, Yu L, Wynn J, Hernan R, Zhou X, Farkouh-Karoleski C, Krishnan US, Khlevner J, De A, Zygmunt A, Crombleholme T, Lim FY, Needelman H, Cusick RA, Mychaliska GB, Warner BW, Wagner AJ, Danko ME, Chung D, Potoka D, Kosiński P, McCulley DJ, Elfiky M, Azarow K, Fialkowski E, Schindel D, Soffer SZ, Lyon JB, Zalieckas JM, Vardarajan BN, Aspelund G, Duron VP, High FA, Sun X, Donahoe PK, Shen Y, Chung WK) Am J Hum Genet 2021 Oct 07;108(10):1964-1980 17 Citations |
1 | Chemogenetic inactivation of the nucleus reuniens impairs object placement memory in female mice. (Schwabe MR, Lincoln CM, Ivers MM, Frick KM) Neurobiol Learn Mem 2021 Nov;185:107521 5 Citations |
1 | Contribution of the Adenosine 2A Receptor to Behavioral Effects of Tetrahydrocannabinol, Cannabidiol and PECS-101. (Stollenwerk TM, Pollock S, Hillard CJ) Molecules 2021 Sep 02;26(17) 6 Citations |
1 | Activation status dictates the function of unlicensed natural killer cells in mice and humans. (Aguilar EG, Dunai C, Judge SJ, Zamora AE, Khuat LT, Vick LV, Collins CP, Stoffel KM, Alvarez M, Barao I, Miller JS, Blazar BR, Chevallier P, Retiere C, Canter RJ, Murphy WJ) Blood Adv 2021 Oct 26;5(20):4219-4232 1 Citation |
1 | Adverse Maternal Environment and Postweaning Western Diet Alter Hepatic CD36 Expression and Methylation Concurrently with Nonalcoholic Fatty Liver Disease in Mouse Offspring. (Fu Q, North PE, Ke X, Huang YW, Fritz KA, Majnik AV, Lane RH) J Nutr 2021 Oct 01;151(10):3102-3112 4 Citations |
1 | Enterically derived high-density lipoprotein restrains liver injury through the portal vein. (Han YH, Onufer EJ, Huang LH, Sprung RW, Davidson WS, Czepielewski RS, Wohltmann M, Sorci-Thomas MG, Warner BW, Randolph GJ) Science 2021 Jul 23;373(6553) 87 Citations |
1 | Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome. (Chu H, Sacharidou A, Nguyen A, Li C, Chambliss KL, Salmon JE, Shen YM, Lo J, Leone GW, Herz J, Hui DY, Marciano DK, Abrahams VM, Natale BV, Montalbano AP, Xiao X, Xu L, Natale DR, Shaul PW, Mineo C) Circ Res 2021 Sep 17;129(7):735-750 9 Citations |
1 | Hepatic cell mobilization for protection against ischemic myocardial injury. (Liu SQ, Troy JB, Luan CH, Guillory RJ) Sci Rep 2021 Aug 04;11(1):15830 2 Citations |
1 | T Cell-Intrinsic Interferon Regulatory Factor 1 Expression Suppresses Differentiation of CD4+ T Cell Populations That Support Chronic Gammaherpesvirus Infection. (Jondle CN, Johnson KE, Mboko WP, Tarakanova VL) J Virol 2021 Sep 27;95(20):e0072621 4 Citations |
2 | Immune cells surveil aberrantly sialylated O-glycans on megakaryocytes to regulate platelet count. (Lee-Sundlov MM, Burns RT, Kim TO, Grozovsky R, Giannini S, Rivadeneyra L, Zheng Y, Glabere SH, Kahr WHA, Abdi R, Despotovic JM, Wang D, Hoffmeister KM) Blood 2021 Dec 09;138(23):2408-2424 11 Citations |
1 | Endothelial BBSome is essential for vascular, metabolic, and retinal functions. (Jiang J, Reho JJ, Bhattarai S, Cherascu I, Hedberg-Buenz A, Meyer KJ, Tayyari F, Rauckhorst AJ, Guo DF, Morgan DA, Taylor EB, Anderson MG, Drack AV, Rahmouni K) Mol Metab 2021 Nov;53:101308 5 Citations |
4 | Thromboelastometry assessment of hemostatic properties in various murine models with coagulopathy and the effect of factor VIII therapeutics. (Schroeder JA, Kuether EA, Fang J, Jing W, Weiler H, Wilcox DA, Montgomery RR, Shi Q) J Thromb Haemost 2021 Oct;19(10):2417-2427 4 Citations |
2 | MyD88 is an essential regulator of NK cell-mediated clearance of MCMV infection. (Dixon KJ, Siebert JR, Wang D, Abel AM, Johnson KE, Riese MJ, Terhune SS, Tarakanova VL, Thakar MS, Malarkannan S) Mol Immunol 2021 Sep;137:94-104 1 Citation |
2 | Vascular effects of disrupting endothelial mTORC1 signaling in obesity. (Reho JJ, Guo DF, Beyer AM, Wegman-Points L, Pierce GL, Rahmouni K) Am J Physiol Regul Integr Comp Physiol 2021 Aug 01;321(2):R228-R237 2 Citations |
1 | MHC Class II Presentation Is Affected by Polymorphism in the H2-Ob Gene and Additional Loci. (Cullum E, Graves AM, Tarakanova VL, Denzin LK, Golovkina T) J Immunol 2021 Jul 01;207(1):5-14 1 Citation |
1 | Conserved Gammaherpesvirus Protein Kinase Counters the Antiviral Effects of Myeloid Cell-Specific STAT1 Expression To Promote the Establishment of Splenic B Cell Latency. (Sylvester PA, Jondle CN, Stoltz KP, Lanham J, Dittel BN, Tarakanova VL) J Virol 2021 Aug 10;95(17):e0085921 5 Citations |
1 | Activation of the Central Renin-Angiotensin System Causes Local Cerebrovascular Dysfunction. (De Silva TM, Modrick ML, Grobe JL, Faraci FM) Stroke 2021 Jul;52(7):2404-2413 8 Citations |
2 | Low-Density Lipoprotein Receptor Suppresses the Endogenous Cholesterol Synthesis Pathway To Oppose Gammaherpesvirus Replication in Primary Macrophages. (Aurubin CA, Knaack DA, Sahoo D, Tarakanova VL) J Virol 2021 Aug 10;95(17):e0064921 2 Citations |
2 | Red light stimulates vasodilation through extracellular vesicle trafficking. (Weihrauch D, Keszler A, Lindemer B, Krolikowski J, Lohr NL) J Photochem Photobiol B 2021 Jul;220:112212 12 Citations |
1 | Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin. (Sridharan V, Johnson KA, Landes RD, Cao M, Singh P, Wagoner G, Hayar A, Sprick ED, Eveld KA, Bhattacharyya A, Krager KJ, Aykin-Burns N, Weiler H, Fernández JA, Griffin JH, Boerma M) PLoS One 2021;16(5):e0252142 9 Citations |
1 | Antitumor effects of iPSC-based cancer vaccine in pancreatic cancer. (Ouyang X, Liu Y, Zhou Y, Guo J, Wei TT, Liu C, Lee B, Chen B, Zhang A, Casey KM, Wang L, Kooreman NG, Habtezion A, Engleman EG, Wu JC) Stem Cell Reports 2021 Jun 08;16(6):1468-1477 24 Citations |
4 | Gut Microbiota Represent a Major Thermogenic Biomass. (Riedl RA, Burnett CML, Pearson NA, Reho JJ, Mokadem M, Edwards RA, Kindel TL, Kirby JR, Grobe JL) Function (Oxf) 2021;2(3):zqab019 17 Citations |
1 | Single-cell RNA sequencing of mouse islets exposed to proinflammatory cytokines. (Stancill JS, Kasmani MY, Khatun A, Cui W, Corbett JA) Life Sci Alliance 2021 Jun;4(6) 16 Citations |
1 | E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation. (Schauder DM, Shen J, Chen Y, Kasmani MY, Kudek MR, Burns R, Cui W) Proc Natl Acad Sci U S A 2021 Apr 20;118(16) 15 Citations |
2 | Gammaherpesvirus Usurps Host IL-17 Signaling To Support the Establishment of Chronic Infection. (Jondle CN, Johnson KE, Aurubin C, Sylvester P, Xin G, Cui W, Huppler AR, Tarakanova VL) mBio 2021 Apr 06;12(2) 8 Citations |
1 | BBSome ablation in SF1 neurons causes obesity without comorbidities. (Rouabhi M, Guo DF, Morgan DA, Zhu Z, López M, Zingman L, Grobe JL, Rahmouni K) Mol Metab 2021 Jun;48:101211 14 Citations |
1 | Toll-like receptor-9 stimulated plasmacytoid dendritic cell precursors suppress autoimmune neuroinflammation in a murine model of multiple sclerosis. (Letscher H, Agbogan VA, Korniotis S, Gastineau P, Tejerina E, Gras C, Mégret J, Moe A, Drobyski WR, Zavala F) Sci Rep 2021 Feb 26;11(1):4735 7 Citations |
1 | Suppression of steroid 5α-reductase type I promotes cellular apoptosis and autophagy via PI3K/Akt/mTOR pathway in multiple myeloma. (Dou R, Qian J, Wu W, Zhang Y, Yuan Y, Guo M, Wei R, Yang S, Jurczyszyn A, Janz S, Beksac M, Gu C, Yang Y) Cell Death Dis 2021 Feb 24;12(2):206 12 Citations |
1 | Interferon Regulatory Factor 3 Supports the Establishment of Chronic Gammaherpesvirus Infection in a Route- and Dose-Dependent Manner. (Johnson KE, Sylvester PA, Jondle CN, Aurubin CA, Tarakanova VL) J Virol 2021 Apr 12;95(9) 4 Citations |
3 | Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer. (Xin G, Chen Y, Topchyan P, Kasmani MY, Burns R, Volberding PJ, Wu X, Cohn A, Chen Y, Lin CW, Ho PC, Silverstein R, Dwinell MB, Cui W) Cancer Immunol Res 2021 Apr;9(4):454-469 19 Citations |
1 | Neutrophil-Derived Myeloperoxidase Facilitates Both the Induction and Elicitation Phases of Contact Hypersensitivity. (Strzepa A, Gurski CJ, Dittel LJ, Szczepanik M, Pritchard KA Jr, Dittel BN) Front Immunol 2020;11:608871 13 Citations |
1 | A single strain of Bacteroides fragilis protects gut integrity and reduces GVHD. (Sofi MH, Wu Y, Ticer T, Schutt S, Bastian D, Choi HJ, Tian L, Mealer C, Liu C, Westwater C, Armeson KE, Alekseyenko AV, Yu XZ) JCI Insight 2021 Feb 08;6(3) 38 Citations |
4 | STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer. (Vonderhaar EP, Barnekow NS, McAllister D, McOlash L, Eid MA, Riese MJ, Tarakanova VL, Johnson BD, Dwinell MB) Cell Mol Gastroenterol Hepatol 2021;12(1):41-58 30 Citations |
1 | Altered offspring neurodevelopment in an arginine vasopressin preeclampsia model. (Gumusoglu SB, Chilukuri ASS, Hing BWQ, Scroggins SM, Kundu S, Sandgren JA, Santillan MK, Santillan DA, Grobe JL, Stevens HE) Transl Psychiatry 2021 Jan 28;11(1):79 12 Citations |
1 | Identification and analysis of circulating long non-coding RNAs with high significance in diabetic cardiomyopathy. (Pant T, Dhanasekaran A, Zhao M, Thorp EB, Forbess JM, Bosnjak ZJ, Benjamin IJ, Ge ZD) Sci Rep 2021 Jan 28;11(1):2571 10 Citations |
1 | STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell function. (Wu Y, Tang CA, Mealer C, Bastian D, Hanief Sofi M, Tian L, Schutt S, Choi HJ, Ticer T, Zhang M, Sui X, Huang L, Mellor AL, Hu CA, Yu XZ) Cell Mol Immunol 2021 Mar;18(3):632-643 4 Citations |
3 | Dissociable effects of dietary sodium in early life upon somatic growth, fluid homeostasis, and spatial memory in mice of both sexes. (Segar JL, Grobe CC, Balapattabi K, Ritter ML, Reho JJ, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2021 Apr 01;320(4):R438-R451 5 Citations |
1 | Interleukin-6 mediates neutrophil mobilization from bone marrow in pulmonary hypertension. (Florentin J, Zhao J, Tai YY, Vasamsetti SB, O'Neil SP, Kumar R, Arunkumar A, Watson A, Sembrat J, Bullock GC, Sanders L, Kassa B, Rojas M, Graham BB, Chan SY, Dutta P) Cell Mol Immunol 2021 Feb;18(2):374-384 31 Citations |
1 | The Histamine 3 Receptor Is Expressed in the Heart and Its Activation Opposes Adverse Cardiac Remodeling in the Angiotensin II Mouse Model. (McCaffrey SL, Lim G, Bullock M, Kasparian AO, Clifton-Bligh R, Campbell WB, Widiapradja A, Levick SP) Int J Mol Sci 2020 Dec 21;21(24) 6 Citations |
1 | 17β-estradiol activation of dorsal hippocampal TrkB is independent of increased mature BDNF expression and is required for enhanced memory consolidation in female mice. (Gross KS, Alf RL, Polzin TR, Frick KM) Psychoneuroendocrinology 2021 Mar;125:105110 13 Citations |
2 | Arid2 regulates hematopoietic stem cell differentiation in normal hematopoiesis. (Bluemn T, Schmitz J, Chen Y, Zheng Y, Zhang Y, Zheng S, Burns R, DeJong J, Christiansen L, Izaguirre-Carbonell J, Wang D, Zhu N) Exp Hematol 2021 Feb;94:37-46 7 Citations |
1 | The miR-23a∼27a∼24-2 microRNA Cluster Promotes Inflammatory Polarization of Macrophages. (Boucher A, Klopfenstein N, Hallas WM, Skibbe J, Appert A, Jang SH, Pulakanti K, Rao S, Cowden Dahl KD, Dahl R) J Immunol 2021 Feb 01;206(3):540-553 13 Citations |
1 | A non-hallucinogenic psychedelic analogue with therapeutic potential. (Cameron LP, Tombari RJ, Lu J, Pell AJ, Hurley ZQ, Ehinger Y, Vargas MV, McCarroll MN, Taylor JC, Myers-Turnbull D, Liu T, Yaghoobi B, Laskowski LJ, Anderson EI, Zhang G, Viswanathan J, Brown BM, Tjia M, Dunlap LE, Rabow ZT, Fiehn O, Wulff H, McCorvy JD, Lein PJ, Kokel D, Ron D, Peters J, Zuo Y, Olson DE) Nature 2021 Jan;589(7842):474-479 176 Citations |
4 | Endothelial Rap1 (Ras-Association Proximate 1) Restricts Inflammatory Signaling to Protect From the Progression of Atherosclerosis. (Singh B, Kosuru R, Lakshmikanthan S, Sorci-Thomas MG, Zhang DX, Sparapani R, Vasquez-Vivar J, Chrzanowska M) Arterioscler Thromb Vasc Biol 2021 Feb;41(2):638-650 21 Citations |
1 | CCL3 contributes to secondary damage after spinal cord injury. (Pelisch N, Rosas Almanza J, Stehlik KE, Aperi BV, Kroner A) J Neuroinflammation 2020 Nov 27;17(1):362 46 Citations |
1 | Tetraspanin CD82 is necessary for muscle stem cell activation and supports dystrophic muscle function. (Hall A, Fontelonga T, Wright A, Bugda Gwilt K, Widrick J, Pasut A, Villa F, Miranti CK, Gibbs D, Jiang E, Meng H, Lawlor MW, Gussoni E) Skelet Muscle 2020 Nov 27;10(1):34 9 Citations |
1 | Mitophagy protects β cells from inflammatory damage in diabetes. (Sidarala V, Pearson GL, Parekh VS, Thompson B, Christen L, Gingerich MA, Zhu J, Stromer T, Ren J, Reck EC, Chai B, Corbett JA, Mandrup-Poulsen T, Satin LS, Soleimanpour SA) JCI Insight 2020 Dec 17;5(24) 57 Citations |
2 | Single-cell lineage mapping of a diverse virus-specific naive CD4 T cell repertoire. (Khatun A, Kasmani MY, Zander R, Schauder DM, Snook JP, Shen J, Wu X, Burns R, Chen YG, Lin CW, Williams MA, Cui W) J Exp Med 2021 Mar 01;218(3) 32 Citations |
2 | Duchenne muscular dystrophy (DMD) cardiomyocyte-secreted exosomes promote the pathogenesis of DMD-associated cardiomyopathy. (Gartz M, Lin CW, Sussman MA, Lawlor MW, Strande JL) Dis Model Mech 2020 Nov 13;13(11) 19 Citations |
1 | Intracellular β1-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility. (Wang Y, Shi Q, Li M, Zhao M, Reddy Gopireddy R, Teoh JP, Xu B, Zhu C, Ireton KE, Srinivasan S, Chen S, Gasser PJ, Bossuyt J, Hell JW, Bers DM, Xiang YK) Circ Res 2021 Jan 22;128(2):246-261 33 Citations |
1 | Post-Translational Modifications of Platelet-Derived Amyloid Precursor Protein by Coagulation Factor XIII-A. (Hur WS, Juang LJ, Mazinani N, Munro L, Jefferies WA, Kastrup CJ) Biochemistry 2020 Nov 24;59(46):4449-4455 2 Citations |
3 | Myh6-driven Cre recombinase activates the DNA damage response and the cell cycle in the myocardium in the absence of loxP sites. (Wang X, Lauth A, Wan TC, Lough JW, Auchampach JA) Dis Model Mech 2020 Dec 18;13(12) 13 Citations |
3 | Quantification of body fluid compartmentalization by combined time-domain nuclear magnetic resonance and bioimpedance spectroscopy. (Segar JL, Balapattabi K, Reho JJ, Grobe CC, Burnett CML, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2021 Jan 01;320(1):R44-R54 10 Citations |
2 | Signaling through the type 2 cannabinoid receptor regulates the severity of acute and chronic graft-versus-host disease. (Yuan CY, Zhou V, Sauber G, Stollenwerk T, Komorowski R, López A, Tolón RM, Romero J, Hillard CJ, Drobyski WR) Blood 2021 Mar 04;137(9):1241-1255 11 Citations |
1 | Inhibition of mitochondrial oxidative metabolism attenuates EMCV replication and protects β-cells from virally mediated lysis. (Stafford JD, Shaheen ZR, Yeo CT, Corbett JA) J Biol Chem 2020 Dec 04;295(49):16655-16664 5 Citations |
1 | Interferon Regulatory Factor 7 Attenuates Chronic Gammaherpesvirus Infection. (Johnson KE, Aurubin CA, Jondle CN, Lange PT, Tarakanova VL) J Virol 2020 Nov 23;94(24) 9 Citations |
1 | The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development. (Miesfeld JB, Ghiasvand NM, Marsh-Armstrong B, Marsh-Armstrong N, Miller EB, Zhang P, Manna SK, Zawadzki RJ, Brown NL, Glaser T) Proc Natl Acad Sci U S A 2020 Sep 01;117(35):21690-21700 23 Citations |
1 | Diffusion tensor distribution imaging of an in vivo mouse brain at ultrahigh magnetic field by spatiotemporal encoding. (Yon M, de Almeida Martins JP, Bao Q, Budde MD, Frydman L, Topgaard D) NMR Biomed 2020 Nov;33(11):e4355 8 Citations |
1 | Regulatory T Cells Contribute to Resistance against Lyme Arthritis. (Siebers EM, Liedhegner ES, Lawlor MW, Schell RF, Nardelli DT) Infect Immun 2020 Oct 19;88(11) 6 Citations |
1 | Apoptosis of hematopoietic progenitor-derived adipose tissue-resident macrophages contributes to insulin resistance after myocardial infarction. (Vasamsetti SB, Coppin E, Zhang X, Florentin J, Koul S, Götberg M, Clugston AS, Thoma F, Sembrat J, Bullock GC, Kostka D, St Croix CM, Chattopadhyay A, Rojas M, Mulukutla SR, Dutta P) Sci Transl Med 2020 Jul 22;12(553) 14 Citations |
1 | Coupling of energy intake and energy expenditure across a temperature spectrum: impact of diet-induced obesity in mice. (Ono-Moore KD, Rutkowsky JM, Pearson NA, Williams DK, Grobe JL, Tolentino T, Lloyd KCK, Adams SH) Am J Physiol Endocrinol Metab 2020 Sep 01;319(3):E472-E484 4 Citations |
1 | Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice. (Wen Z, Rajagopalan A, Flietner ED, Yun G, Chesi M, Furumo Q, Burns RT, Papadas A, Ranheim EA, Pagenkopf AC, Morrow ZT, Finn R, Zhou Y, Li S, You X, Jensen J, Yu M, Cicala A, Menting J, Mitsiades CS, Callander NS, Bergsagel PL, Wang D, Asimakopoulos F, Zhang J) Blood 2021 Jan 07;137(1):61-74 16 Citations |
2 | Bilateral cervical contusion spinal cord injury: A mouse model to evaluate sensorimotor function. (Reinhardt DR, Stehlik KE, Satkunendrarajah K, Kroner A) Exp Neurol 2020 Sep;331:113381 12 Citations |
1 | Assessment of tumor treatment response using active contrast encoding (ACE)-MRI: Comparison with conventional DCE-MRI. (Zhang J, Winters K, Kiser K, Baboli M, Kim SG) PLoS One 2020;15(6):e0234520 6 Citations |
1 | In vivo enrichment of genetically manipulated platelets for murine hemophilia B gene therapy. (Chen Y, Schroeder JA, Gao C, Li J, Hu J, Shi Q) J Cell Physiol 2021 Jan;236(1):354-365 5 Citations |
1 | Long Range Endocrine Delivery of Circulating miR-210 to Endothelium Promotes Pulmonary Hypertension. (Zhao J, Florentin J, Tai YY, Torrino S, Ohayon L, Brzoska T, Tang Y, Yang J, Negi V, Woodcock CC, Risbano MG, Nouraie SM, Sundd P, Bertero T, Dutta P, Chan SY) Circ Res 2020 Aug 14;127(5):677-692 19 Citations |
2 | Satellite glial cells in sensory ganglia express functional transient receptor potential ankyrin 1 that is sensitized in neuropathic and inflammatory pain. (Shin SM, Itson-Zoske B, Cai Y, Qiu C, Pan B, Stucky CL, Hogan QH, Yu H) Mol Pain 2020;16:1744806920925425 28 Citations |
1 | SAK3 Administration Improves Spine Abnormalities and Cognitive Deficits in AppNL-G-F/NL-G-F Knock-in Mice by Increasing Proteasome Activity through CaMKII/Rpt6 Signaling. (Izumi H, Kawahata I, Shinoda Y, Helmstetter FJ, Fukunaga K) Int J Mol Sci 2020 May 28;21(11) 7 Citations |
1 | Endogenous levels of 1-O-acylceramides increase upon acidic ceramidase deficiency and decrease due to loss of Dgat1 in a tissue-dependent manner. (Bayerle A, Marsching C, Rabionet M, Dworski S, Kamani MA, Chitraju C, Gluchowski NL, Gabriel KR, Herzer S, Jennemann R, Levade T, Medin JA, Sandhoff R) Biochim Biophys Acta Mol Cell Biol Lipids 2020 Sep;1865(9):158741 7 Citations |
3 | Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension. (Wu J, Agbor LN, Fang S, Mukohda M, Nair AR, Nakagawa P, Sharma A, Morgan DA, Grobe JL, Rahmouni K, Weiss RM, McCormick JA, Sigmund CD) Cardiovasc Res 2021 Jan 01;117(1):308-319 18 Citations |
4 | Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature. (Yang C, Siebert JR, Burns R, Zheng Y, Mei A, Bonacci B, Wang D, Urrutia RA, Riese MJ, Rao S, Carlson KS, Thakar MS, Malarkannan S) Elife 2020 May 14;9 16 Citations |
1 | Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes. (Hesterberg RS, Beatty MS, Han Y, Fernandez MR, Akuffo AA, Goodheart WE, Yang C, Chang S, Colin CM, Alontaga AY, McDaniel JM, Mailloux AW, Billington JMR, Yue L, Russell S, Gillies RJ, Yun SY, Ayaz M, Lawrence NJ, Lawrence HR, Yu XZ, Fu J, Darville LN, Koomen JM, Ren X, Messina J, Jiang K, Garrett TJ, Rajadhyaksha AM, Cleveland JL, Epling-Burnette PK) Blood 2020 Aug 13;136(7):857-870 15 Citations |
1 | B Cell-Intrinsic Expression of Interferon Regulatory Factor 1 Supports Chronic Murine Gammaherpesvirus 68 Infection. (Jondle CN, Johnson KE, Uitenbroek AA, Sylvester PA, Nguyen C, Cui W, Tarakanova VL) J Virol 2020 Jun 16;94(13) 7 Citations |
1 | Truncated (N)-Methanocarba Nucleosides as Partial Agonists at Mouse and Human A3 Adenosine Receptors: Affinity Enhancement by N6-(2-Phenylethyl) Substitution. (Tosh DK, Salmaso V, Rao H, Bitant A, Fisher CL, Lieberman DI, Vorbrüggen H, Reitman ML, Gavrilova O, Gao ZG, Auchampach JA, Jacobson KA) J Med Chem 2020 Apr 23;63(8):4334-4348 17 Citations |
1 | Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis. (Wang X, Cai B, Yang X, Sonubi OO, Zheng Z, Ramakrishnan R, Shi H, Valenti L, Pajvani UB, Sandhu J, Infante RE, Radhakrishnan A, Covey DF, Guan KL, Buck J, Levin LR, Tontonoz P, Schwabe RF, Tabas I) Cell Metab 2020 May 05;31(5):969-986.e7 100 Citations |
2 | Inhibition of myeloperoxidase increases revascularization and improves blood flow in a diabetic mouse model of hindlimb ischaemia. (Weihrauch D, Martin DP, Jones D, Krolikowski J, Struve J, Naylor S, Pritchard KA Jr) Diab Vasc Dis Res 2020;17(3):1479164120907971 5 Citations |
1 | Feeding Formula Eliminates the Necessity of Bacterial Dysbiosis and Induces Inflammation and Injury in the Paneth Cell Disruption Murine NEC Model in an Osmolality-Dependent Manner. (Lueschow SR, Kern SL, Gong H, Grobe JL, Segar JL, Carlson SJ, McElroy SJ) Nutrients 2020 Mar 26;12(4) 10 Citations |
1 | The TRPM2 Ion Channel Regulates Inflammatory Functions of Neutrophils During Listeria monocytogenes Infection. (Robledo-Avila FH, Ruiz-Rosado JD, Brockman KL, Partida-Sánchez S) Front Immunol 2020;11:97 16 Citations |
1 | Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb. (Laitila JM, McNamara EL, Wingate CD, Goullee H, Ross JA, Taylor RL, van der Pijl R, Griffiths LM, Harries R, Ravenscroft G, Clayton JS, Sewry C, Lawlor MW, Ottenheijm CAC, Bakker AJ, Ochala J, Laing NG, Wallgren-Pettersson C, Pelin K, Nowak KJ) Acta Neuropathol Commun 2020 Feb 17;8(1):18 8 Citations |
1 | Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury. (Yurdagul A Jr, Subramanian M, Wang X, Crown SB, Ilkayeva OR, Darville L, Kolluru GK, Rymond CC, Gerlach BD, Zheng Z, Kuriakose G, Kevil CG, Koomen JM, Cleveland JL, Muoio DM, Tabas I) Cell Metab 2020 Mar 03;31(3):518-533.e10 205 Citations |
2 | β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis. (Giannini S, Lee-Sundlov MM, Rivadeneyra L, Di Buduo CA, Burns R, Lau JT, Falet H, Balduini A, Hoffmeister KM) Nat Commun 2020 Jan 17;11(1):356 32 Citations |
1 | Pathogenic Bhlhe40+ GM-CSF+ CD4+ T cells promote indirect alloantigen presentation in the GI tract during GVHD. (Piper C, Zhou V, Komorowski R, Szabo A, Vincent B, Serody J, Alegre ML, Edelson BT, Taneja R, Drobyski WR) Blood 2020 Feb 20;135(8):568-581 29 Citations |
3 | Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice. (Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, Santillan DA, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL) Hypertension 2020 Feb;75(2):569-579 21 Citations |
1 | Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis. (Cai B, Dongiovanni P, Corey KE, Wang X, Shmarakov IO, Zheng Z, Kasikara C, Davra V, Meroni M, Chung RT, Rothlin CV, Schwabe RF, Blaner WS, Birge RB, Valenti L, Tabas I) Cell Metab 2020 Feb 04;31(2):406-421.e7 133 Citations |
1 | The Interleukin (IL) 17R/IL-22R Signaling Axis Is Dispensable for Vulvovaginal Candidiasis Regardless of Estrogen Status. (Peters BM, Coleman BM, Willems HME, Barker KS, Aggor FEY, Cipolla E, Verma AH, Bishu S, Huppler AH, Bruno VM, Gaffen SL) J Infect Dis 2020 Apr 07;221(9):1554-1563 35 Citations |
1 | In Vivo Assessment of NK Cell-Mediated Cytotoxicity by Adoptively Transferred Splenocyte Rejection. (Schloemer NJ, Abel AM, Thakar MS, Malarkannan S) Methods Mol Biol 2020;2097:115-123 |
1 | Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD). (Halberstadt AL, Chatha M, Klein AK, McCorvy JD, Meyer MR, Wagmann L, Stratford A, Brandt SD) Neuropharmacology 2020 Aug 01;172:107856 20 Citations |
1 | Sensory cortical control of movement. (Karadimas SK, Satkunendrarajah K, Laliberte AM, Ringuette D, Weisspapir I, Li L, Gosgnach S, Fehlings MG) Nat Neurosci 2020 Jan;23(1):75-84 36 Citations |
1 | Generation of PECAM-1 (CD31) conditional knockout mice. (Zhi H, Kanaji T, Fu G, Newman DK, Newman PJ) Genesis 2020 Feb;58(2):e23346 6 Citations |
1 | Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion. (Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman A, Aifantis I, Boccalatte F, Wang L, Jin M, Khoury J, Wang W, Hu S, Yuan Y, Wang E, Yuan J, Janz S, Colgan J, Habelhah H, Waldschmidt T, Müschen M, Bagg A, Darbro B, Zhao C) Blood 2020 Jan 09;135(2):108-120 16 Citations |
1 | Genome-wide differential expression profiling of lncRNAs and mRNAs associated with early diabetic cardiomyopathy. (Pant T, Dhanasekaran A, Bai X, Zhao M, Thorp EB, Forbess JM, Bosnjak ZJ, Ge ZD) Sci Rep 2019 Oct 25;9(1):15345 24 Citations |
1 | Role of thrombomodulin expression on hematopoietic stem cells. (Basu S, Liang HPH, Hernandez I, Zogg M, Fields B, May J, Ogoti Y, Wyseure T, Mosnier LO, Burns RT, Carlson K, Weiler H) J Thromb Haemost 2020 Jan;18(1):123-135 3 Citations |
1 | Dorsal Hippocampal Actin Polymerization Is Necessary for Activation of G-Protein-Coupled Estrogen Receptor (GPER) to Increase CA1 Dendritic Spine Density and Enhance Memory Consolidation. (Kim J, Schalk JC, Koss WA, Gremminger RL, Taxier LR, Gross KS, Frick KM) J Neurosci 2019 Nov 27;39(48):9598-9610 33 Citations |
6 | Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses. (Chen Y, Yang M, Huang W, Chen W, Zhao Y, Schulte ML, Volberding P, Gerbec Z, Zimmermann MT, Zeighami A, Demos W, Zhang J, Knaack DA, Smith BC, Cui W, Malarkannan S, Sodhi K, Shapiro JI, Xie Z, Sahoo D, Silverstein RL) Circ Res 2019 Dec 06;125(12):1087-1102 103 Citations |
1 | Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress. (Oleinik N, Kim J, Roth BM, Selvam SP, Gooz M, Johnson RH, Lemasters JJ, Ogretmen B) Sci Adv 2019 Sep;5(9):eaax1978 35 Citations |
1 | The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4. (Pathak SS, Liu D, Li T, de Zavalia N, Zhu L, Li J, Karthikeyan R, Alain T, Liu AC, Storch KF, Kaufman RJ, Jin VX, Amir S, Sonenberg N, Cao R) Neuron 2019 Nov 20;104(4):724-735.e6 38 Citations |
4 | Mirc11 Disrupts Inflammatory but Not Cytotoxic Responses of NK Cells. (Nanbakhsh A, Srinivasamani A, Holzhauer S, Riese MJ, Zheng Y, Wang D, Burns R, Reimer MH, Rao S, Lemke A, Tsaih SW, Flister MJ, Lao S, Dahl R, Thakar MS, Malarkannan S) Cancer Immunol Res 2019 Oct;7(10):1647-1662 10 Citations |
2 | Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1. (Mammoto T, Torisawa YS, Muyleart M, Hendee K, Anugwom C, Gutterman D, Mammoto A) Aging (Albany NY) 2019 Sep 05;11(17):7051-7069 19 Citations |
1 | Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21. (Sahu BS, Rodriguez P, Nguyen ME, Han R, Cero C, Razzoli M, Piaggi P, Laskowski LJ, Pavlicev M, Muglia L, Mahata SK, O'Grady S, McCorvy JD, Baier LJ, Sham YY, Bartolomucci A) Cell Rep 2019 Sep 03;28(10):2567-2580.e6 18 Citations |
1 | All trans-retinoic acid protects against acute ischemic stroke by modulating neutrophil functions through STAT1 signaling. (Cai W, Wang J, Hu M, Chen X, Lu Z, Bellanti JA, Zheng SG) J Neuroinflammation 2019 Aug 31;16(1):175 62 Citations |
1 | Synergistic Genetic Interactions between Pkhd1 and Pkd1 Result in an ARPKD-Like Phenotype in Murine Models. (Olson RJ, Hopp K, Wells H, Smith JM, Furtado J, Constans MM, Escobar DL, Geurts AM, Torres VE, Harris PC) J Am Soc Nephrol 2019 Nov;30(11):2113-2127 31 Citations |
1 | Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity. (Chakraborty P, Vaena SG, Thyagarajan K, Chatterjee S, Al-Khami A, Selvam SP, Nguyen H, Kang I, Wyatt MW, Baliga U, Hedley Z, Ngang RN, Guo B, Beeson GC, Husain S, Paulos CM, Beeson CC, Zilliox MJ, Hill EG, Mehrotra M, Yu XZ, Ogretmen B, Mehrotra S) Cell Rep 2019 Aug 13;28(7):1879-1893.e7 66 Citations |
1 | B cells suppress medullary granulopoiesis by an extracellular glycosylation-dependent mechanism. (Irons EE, Lee-Sundlov MM, Zhu Y, Neelamegham S, Hoffmeister KM, Lau JT) Elife 2019 Aug 13;8 17 Citations |
1 | Modeling Human Cancer-induced Cachexia. (Talbert EE, Cuitiño MC, Ladner KJ, Rajasekerea PV, Siebert M, Shakya R, Leone GW, Ostrowski MC, Paleo B, Weisleder N, Reiser PJ, Webb A, Timmers CD, Eiferman DS, Evans DC, Dillhoff ME, Schmidt CR, Guttridge DC) Cell Rep 2019 Aug 06;28(6):1612-1622.e4 77 Citations |
3 | Modification of HDL by reactive aldehydes alters select cardioprotective functions of HDL in macrophages. (Schill RL, Knaack DA, Powers HR, Chen Y, Yang M, Schill DJ, Silverstein RL, Sahoo D) FEBS J 2020 Feb;287(4):695-707 11 Citations |
3 | Adverse early-life environment impairs postnatal lung development in mice. (Lai PY, Jing X, Michalkiewicz T, Entringer B, Ke X, Majnik A, Kriegel AJ, Liu P, Lane RH, Konduri GG) Physiol Genomics 2019 Sep 01;51(9):462-470 11 Citations |
1 | Metal-independent variants of phosphoglycerate mutase promote resistance to nutritional immunity and retention of glycolysis during infection. (Radin JN, Kelliher JL, Solórzano PKP, Grim KP, Ramezanifard R, Slauch JM, Kehl-Fie TE) PLoS Pathog 2019 Jul;15(7):e1007971 23 Citations |
1 | Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation. (Lin S, Liu W, Chen CL, Sun D, Hu JX, Li L, Ye J, Mei L, Xiong WC) J Mol Cell Biol 2020 Jan 22;12(1):17-31 12 Citations |
1 | Platelet-derived extracellular vesicles released after trauma promote hemostasis and contribute to DVT in mice. (Dyer MR, Alexander W, Hassoune A, Chen Q, Brzoska T, Alvikas J, Liu Y, Haldeman S, Plautz W, Loughran P, Li H, Boone B, Sadovsky Y, Sundd P, Zuckerbraun BS, Neal MD) J Thromb Haemost 2019 Oct;17(10):1733-1745 45 Citations |
1 | Extrusion pump ABCC1 was first linked with nonsyndromic hearing loss in humans by stepwise genetic analysis. (Li M, Mei L, He C, Chen H, Cai X, Liu Y, Tian R, Tian Q, Song J, Jiang L, Liu C, Wu H, Li T, Liu J, Li X, Yi Y, Yan D, Blanton SH, Hu Z, Liu X, Li J, Ling J, Feng Y) Genet Med 2019 Dec;21(12):2744-2754 18 Citations |
1 | Dickkopf-1 blocks 17β-estradiol-enhanced object memory consolidation in ovariectomized female mice. (Taxier LR, Philippi SM, Fortress AM, Frick KM) Horm Behav 2019 Aug;114:104545 6 Citations |
1 | Radiation and host retinoic acid signaling promote the induction of gut-homing donor T cells after allogeneic hematopoietic stem cell transplantation. (Zheng J, Taylor B, Dodge J, Stephans A, Zheng SG, Chen Q, Chen X) Am J Transplant 2020 Jan;20(1):64-74 2 Citations |
1 | The female reproductive tract contains multiple innate sialic acid-binding immunoglobulin-like lectins (Siglecs) that facilitate sperm survival. (Tecle E, Reynoso HS, Wang R, Gagneux P) J Biol Chem 2019 Aug 02;294(31):11910-11919 26 Citations |
1 | Presynaptic Expression of LRIT3 Transsynaptically Organizes the Postsynaptic Glutamate Signaling Complex Containing TRPM1. (Hasan N, Pangeni G, Cobb CA, Ray TA, Nettesheim ER, Ertel KJ, Lipinski DM, McCall MA, Gregg RG) Cell Rep 2019 Jun 11;27(11):3107-3116.e3 29 Citations |
1 | Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension. (Agbor LN, Nair AR, Wu J, Lu KT, Davis DR, Keen HL, Quelle FW, McCormick JA, Singer JD, Sigmund CD) JCI Insight 2019 Jun 11;5(14) 24 Citations |
1 | RASA1-dependent cellular export of collagen IV controls blood and lymphatic vascular development. (Chen D, Teng JM, North PE, Lapinski PE, King PD) J Clin Invest 2019 Jun 11;129(9):3545-3561 40 Citations |
1 | γ-herpesvirus latency attenuates Mycobacterium tuberculosis infection in mice. (Miller HE, Johnson KE, Tarakanova VL, Robinson RT) Tuberculosis (Edinb) 2019 May;116:56-60 5 Citations |
1 | Topical tranexamic acid inhibits fibrinolysis more effectively when formulated with self-propelling particles. (Baylis JR, Lee MM, St John AE, Wang X, Simonson E, Cau M, Kazerooni A, Gusti V, Statz ML, Yoon JSJ, Liggins RT, White NJ, Kastrup CJ) J Thromb Haemost 2019 Oct;17(10):1645-1654 7 Citations |
1 | Diacylglycerol Lipase-Alpha Regulates Hippocampal-Dependent Learning and Memory Processes in Mice. (Schurman LD, Carper MC, Moncayo LV, Ogasawara D, Richardson K, Yu L, Liu X, Poklis JL, Liu QS, Cravatt BF, Lichtman AH) J Neurosci 2019 Jul 24;39(30):5949-5965 16 Citations |
4 | Aurora kinase B-phosphorylated HP1α functions in chromosomal instability. (Williams MM, Mathison AJ, Christensen T, Greipp PT, Knutson DL, Klee EW, Zimmermann MT, Iovanna J, Lomberk GA, Urrutia RA) Cell Cycle 2019 Jun;18(12):1407-1421 6 Citations |
3 | Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Protects From Angiotensin II-Induced Endothelial Dysfunction in Adult Offspring Born From Pregnancies Complicated by Hypertension. (Nair AR, Silva SD Jr, Agbor LN, Wu J, Nakagawa P, Mukohda M, Lu KT, Sandgren JA, Pierce GL, Santillan MK, Grobe JL, Sigmund CD) Hypertension 2019 Jul;74(1):173-183 16 Citations |
5 | Critical role of Jumonji domain of JMJD1C in MLL-rearranged leukemia. (Izaguirre-Carbonell J, Christiansen L, Burns R, Schmitz J, Li C, Mokry RL, Bluemn T, Zheng Y, Shen J, Carlson KS, Rao S, Wang D, Zhu N) Blood Adv 2019 May 14;3(9):1499-1511 18 Citations |
1 | Chemogenetic Suppression of Medial Prefrontal-Dorsal Hippocampal Interactions Prevents Estrogenic Enhancement of Memory Consolidation in Female Mice. (Tuscher JJ, Taxier LR, Schalk JC, Haertel JM, Frick KM) eNeuro 2019;6(2) 20 Citations |
1 | Sex-specific regulation of stress-induced fetal glucocorticoid surge by the mouse placenta. (Wieczorek A, Perani CV, Nixon M, Constancia M, Sandovici I, Zazara DE, Leone G, Zhang MZ, Arck PC, Solano ME) Am J Physiol Endocrinol Metab 2019 Jul 01;317(1):E109-E120 36 Citations |
1 | Thioredoxin-1 improves the immunometabolic phenotype of antitumor T cells. (Chakraborty P, Chatterjee S, Kesarwani P, Thyagarajan K, Iamsawat S, Dalheim A, Nguyen H, Selvam SP, Nasarre P, Scurti G, Hardiman G, Maulik N, Ball L, Gangaraju V, Rubinstein MP, Klauber-DeMore N, Hill EG, Ogretmen B, Yu XZ, Nishimura MI, Mehrotra S) J Biol Chem 2019 Jun 07;294(23):9198-9212 26 Citations |
1 | D2 Dopamine Receptor G Protein-Biased Partial Agonists Based on Cariprazine. (Shen Y, McCorvy JD, Martini ML, Rodriguiz RM, Pogorelov VM, Ward KM, Wetsel WC, Liu J, Roth BL, Jin J) J Med Chem 2019 May 09;62(9):4755-4771 15 Citations |
1 | Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8+ T-Cell Activation. (Wang Z, Vaughan TY, Zhu W, Chen Y, Fu G, Medrzycki M, Nishio H, Bunting ST, Hankey-Giblin PA, Nusrat A, Parkos CA, Wang D, Wen R, Bunting KD) Front Immunol 2019;10:486 11 Citations |
1 | Comparison of the Effects of High-Fat Diet on Energy Flux in Mice Using Two Multiplexed Metabolic Phenotyping Systems. (Soto JE, Burnett CML, Ten Eyck P, Abel ED, Grobe JL) Obesity (Silver Spring) 2019 May;27(5):793-802 22 Citations |
1 | IL-27 promotes NK cell effector functions via Maf-Nrf2 pathway during influenza infection. (Kumar P, Rajasekaran K, Nanbakhsh A, Gorski J, Thakar MS, Malarkannan S) Sci Rep 2019 Mar 21;9(1):4984 18 Citations |
1 | Chronic intermittent hypoxia enhances disease progression in myeloma-resistant mice. (Ali M, Kowkuntla S, Delloro DJ, Galambos C, Hathi D, Janz S, Shokeen M, Tripathi C, Xu H, Yuk J, Zhan F, Tomasson MH, Bates ML) Am J Physiol Regul Integr Comp Physiol 2019 May 01;316(5):R678-R686 8 Citations |
1 | Combined congenic mapping and nuclease-based gene targeting for studying allele-specific effects of Tnfrsf9 within the Idd9.3 autoimmune diabetes locus. (Forsberg MH, Foda B, Serreze DV, Chen YG) Sci Rep 2019 Mar 13;9(1):4316 7 Citations |
1 | CCR5 is a required signaling receptor for macrophage expression of inflammatory genes in response to viral double-stranded RNA. (Shaheen ZR, Christmann BS, Stafford JD, Moran JM, Buller RML, Corbett JA) Am J Physiol Regul Integr Comp Physiol 2019 May 01;316(5):R525-R534 15 Citations |
2 | Sortase-Dependent Proteins Promote Gastrointestinal Colonization by Enterococci. (Banla LI, Pickrum AM, Hayward M, Kristich CJ, Salzman NH) Infect Immun 2019 Mar;87(5) 10 Citations |
1 | Periostin/β1integrin interaction regulates p21-activated kinases in valvular interstitial cell survival and in actin cytoskeleton reorganization. (Ghatak S, Misra S, Moreno-Rodrigue RA, Hascall VC, Leone GW, Markwald RR) Biochim Biophys Acta Gen Subj 2019 May;1863(5):813-829 9 Citations |
3 | Ability of CP-532,903 to protect mouse hearts from ischemia/reperfusion injury is dependent on expression of A3 adenosine receptors in cardiomyoyctes. (Wan TC, Tampo A, Kwok WM, Auchampach JA) Biochem Pharmacol 2019 May;163:21-31 9 Citations |
1 | Liver Derived FGF21 Maintains Core Body Temperature During Acute Cold Exposure. (Ameka M, Markan KR, Morgan DA, BonDurant LD, Idiga SO, Naber MC, Zhu Z, Zingman LV, Grobe JL, Rahmouni K, Potthoff MJ) Sci Rep 2019 Jan 24;9(1):630 63 Citations |
1 | Activation of androgen receptors protects intact male mice from memory impairments caused by aromatase inhibition. (Koss WA, Frick KM) Horm Behav 2019 May;111:96-104 30 Citations |
2 | Mature IgDlow/- B cells maintain tolerance by promoting regulatory T cell homeostasis. (Ray A, Khalil MI, Pulakanti KL, Burns RT, Gurski CJ, Basu S, Wang D, Rao S, Dittel BN) Nat Commun 2019 Jan 14;10(1):190 23 Citations |
1 | Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases. (Lee D, Pagire HS, Pagire SH, Bae EJ, Dighe M, Kim M, Lee KM, Jang YK, Jaladi AK, Jung KY, Yoo EK, Gim HE, Lee S, Choi WI, Chi YI, Song JS, Bae MA, Jeon YH, Lee GH, Liu KH, Lee T, Park S, Jeon JH, Lee IK, Ahn JH) J Med Chem 2019 Jan 24;62(2):575-588 18 Citations |
1 | Ventral Pallidum Is the Primary Target for Accumbens D1 Projections Driving Cocaine Seeking. (Pardo-Garcia TR, Garcia-Keller C, Penaloza T, Richie CT, Pickel J, Hope BT, Harvey BK, Kalivas PW, Heinsbroek JA) J Neurosci 2019 Mar 13;39(11):2041-2051 65 Citations |
2 | LRP5 in age-related changes in vascular and alveolar morphogenesis in the lung. (Mammoto A, Muyleart M, Mammoto T) Aging (Albany NY) 2019 Jan 05;11(1):89-103 10 Citations |
1 | Design and in Vivo Characterization of A1 Adenosine Receptor Agonists in the Native Ribose and Conformationally Constrained (N)-Methanocarba Series. (Tosh DK, Rao H, Bitant A, Salmaso V, Mannes P, Lieberman DI, Vaughan KL, Mattison JA, Rothwell AC, Auchampach JA, Ciancetta A, Liu N, Cui Z, Gao ZG, Reitman ML, Gavrilova O, Jacobson KA) J Med Chem 2019 Feb 14;62(3):1502-1522 19 Citations |
1 | LXR Alpha Restricts Gammaherpesvirus Reactivation from Latently Infected Peritoneal Cells. (Lange PT, Jondle CN, Darrah EJ, Johnson KE, Tarakanova VL) J Virol 2019 Mar 15;93(6) 16 Citations |
1 | Adverse maternal environment leads to cardiac fibrosis in adult male mice. (Spearman AD, Ke X, Fu Q, Lane RH, Majnik A) Birth Defects Res 2018 Dec 01;110(20):1551-1555 8 Citations |
1 | CD36 Enhances Vascular Smooth Muscle Cell Proliferation and Development of Neointimal Hyperplasia. (Yue H, Febbraio M, Klenotic PA, Kennedy DJ, Wu Y, Chen S, Gohara AF, Li O, Belcher A, Kuang B, McIntyre TM, Silverstein RL, Li W) Arterioscler Thromb Vasc Biol 2019 Feb;39(2):263-275 29 Citations |
1 | Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. (Nguyen H, Kuril S, Bastian D, Kim J, Zhang M, Vaena SG, Dany M, Dai M, Heinrichs JL, Daenthanasanmak A, Iamsawat S, Schutt S, Fu J, Wu Y, Fairlie DP, Atkinson C, Ogretmen B, Tomlinson S, Yu XZ) JCI Insight 2018 Dec 20;3(24) 24 Citations |
2 | Defective collagen binding and increased bleeding in a murine model of von Willebrand disease affecting collagen IV binding. (Slobodianuk TL, Kochelek C, Foeckler J, Kalloway S, Weiler H, Flood VH) J Thromb Haemost 2019 Jan;17(1):63-71 7 Citations |
4 | Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis. (Martin-Mateos R, De Assuncao TM, Arab JP, Jalan-Sakrikar N, Yaqoob U, Greuter T, Verma VK, Mathison AJ, Cao S, Lomberk G, Mathurin P, Urrutia R, Huebert RC, Shah VH) Cell Mol Gastroenterol Hepatol 2019;7(1):197-209 50 Citations |
1 | An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1. (Zheng Z, Nayak L, Wang W, Yurdagul A Jr, Wang X, Cai B, Lapping S, Ozcan L, Ramakrishnan R, Pestell RG, Jain MK, Tabas I) Blood 2019 Feb 14;133(7):743-753 22 Citations |
1 | Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice. (Daenthanasanmak A, Iamsawat S, Chakraborty P, Nguyen HD, Bastian D, Liu C, Mehrotra S, Yu XZ) Blood 2019 Jan 17;133(3):266-279 56 Citations |
2 | Disruption of FOXP3-EZH2 Interaction Represents a Pathobiological Mechanism in Intestinal Inflammation. (Bamidele AO, Svingen PA, Sagstetter MR, Sarmento OF, Gonzalez M, Braga Neto MB, Kugathasan S, Lomberk G, Urrutia RA, Faubion WA Jr) Cell Mol Gastroenterol Hepatol 2019;7(1):55-71 23 Citations |
2 | Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infection. (Xin G, Zander R, Schauder DM, Chen Y, Weinstein JS, Drobyski WR, Tarakanova V, Craft J, Cui W) Nat Commun 2018 Nov 28;9(1):5037 60 Citations |
1 | Kif17 phosphorylation regulates photoreceptor outer segment turnover. (Lewis TR, Kundinger SR, Link BA, Insinna C, Besharse JC) BMC Cell Biol 2018 Nov 20;19(1):25 25 Citations |
1 | Fetal hyperglycemia acutely induces persistent insulin resistance in skeletal muscle. (Kua KL, Hu S, Wang C, Yao J, Dang D, Sawatzke AB, Segar JL, Wang K, Norris AW) J Endocrinol 2019 Jul 01;242(1):M1-M15 12 Citations |
1 | A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis. (Volk A, Liang K, Suraneni P, Li X, Zhao J, Bulic M, Marshall S, Pulakanti K, Malinge S, Taub J, Ge Y, Rao S, Bartom E, Shilatifard A, Crispino JD) Cancer Cell 2018 Nov 12;34(5):707-723.e7 50 Citations |
2 | Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. (Huang LH, Zinselmeyer BH, Chang CH, Saunders BT, Elvington A, Baba O, Broekelmann TJ, Qi L, Rueve JS, Swartz MA, Kim BS, Mecham RP, Wiig H, Thomas MJ, Sorci-Thomas MG, Randolph GJ) Cell Metab 2019 Feb 05;29(2):475-487.e7 36 Citations |
1 | Dynamic Expression Profiles of Sox9 in Embryonic, Post Natal, and Adult Heart Valve Cell Populations. (Gallina D, Lincoln J) Anat Rec (Hoboken) 2019 Jan;302(1):108-116 8 Citations |
1 | Chemogenetic inactivation of the dorsal hippocampus and medial prefrontal cortex, individually and concurrently, impairs object recognition and spatial memory consolidation in female mice. (Tuscher JJ, Taxier LR, Fortress AM, Frick KM) Neurobiol Learn Mem 2018 Dec;156:103-116 58 Citations |
1 | Effect of Human Corneal Mesenchymal Stromal Cell-derived Exosomes on Corneal Epithelial Wound Healing. (Samaeekia R, Rabiee B, Putra I, Shen X, Park YJ, Hematti P, Eslani M, Djalilian AR) Invest Ophthalmol Vis Sci 2018 Oct 01;59(12):5194-5200 145 Citations |
1 | A Destabilizing Domain Allows for Fast, Noninvasive, Conditional Control of Protein Abundance in the Mouse Eye - Implications for Ocular Gene Therapy. (Datta S, Renwick M, Chau VQ, Zhang F, Nettesheim ER, Lipinski DM, Hulleman JD) Invest Ophthalmol Vis Sci 2018 Oct 01;59(12):4909-4920 15 Citations |
3 | Tumor suppressor Interferon Regulatory Factor 1 selectively blocks expression of endogenous retrovirus. (Stoltz KP, Jondle CN, Pulakanti K, Sylvester PA, Urrutia R, Rao S, Tarakanova VL) Virology 2019 Jan 02;526:52-60 8 Citations |
4 | IL-13 promotes in vivo neonatal cardiomyocyte cell cycle activity and heart regeneration. (Wodsedalek DJ, Paddock SJ, Wan TC, Auchampach JA, Kenarsary A, Tsaih SW, Flister MJ, O'Meara CC) Am J Physiol Heart Circ Physiol 2019 Jan 01;316(1):H24-H34 32 Citations |
1 | Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response. (Chatterjee S, Chakraborty P, Daenthanasanmak A, Iamsawat S, Andrejeva G, Luevano LA, Wolf M, Baliga U, Krieg C, Beeson CC, Mehrotra M, Hill EG, Rathmell JC, Yu XZ, Kraft AS, Mehrotra S) Clin Cancer Res 2019 Feb 01;25(3):1036-1049 31 Citations |
1 | Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma. (Ananieva EA, Bostic JN, Torres AA, Glanz HR, McNitt SM, Brenner MK, Boyer MP, Addington AK, Hutson SM) Br J Cancer 2018 Oct;119(8):1009-1017 15 Citations |
1 | Early Immunologic Response of Irreversible Electroporation versus Cryoablation in a Rodent Model of Pancreatic Cancer. (White SB, Zhang Z, Chen J, Gogineni VR, Larson AC) J Vasc Interv Radiol 2018 Dec;29(12):1764-1769 48 Citations |
3 | Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway. (Seo S, Mathison A, Grzenda A, Podratz J, Calvo E, Brimijoin S, Windebank A, Iovanna J, Lomberk G, Urrutia R) Sci Rep 2018 Oct 10;8(1):15077 4 Citations |
2 | Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice. (Sandgren JA, Deng G, Linggonegoro DW, Scroggins SM, Perschbacher KJ, Nair AR, Nishimura TE, Zhang SY, Agbor LN, Wu J, Keen HL, Naber MC, Pearson NA, Zimmerman KA, Weiss RM, Bowdler NC, Usachev YM, Santillan DA, Potthoff MJ, Pierce GL, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL) JCI Insight 2018 Oct 04;3(19) 55 Citations |
1 | Propofol Alters Long Non-Coding RNA Profiles in the Neonatal Mouse Hippocampus: Implication of Novel Mechanisms in Anesthetic-Induced Developmental Neurotoxicity. (Logan S, Jiang C, Yan Y, Inagaki Y, Arzua T, Bai X) Cell Physiol Biochem 2018;49(6):2496-2510 21 Citations |
1 | Signaling network between the dysregulated expression of microRNAs and mRNAs in propofol-induced developmental neurotoxicity in mice. (Jiang C, Logan S, Yan Y, Inagaki Y, Arzua T, Ma P, Lu S, Bosnjak ZJ, Bai X) Sci Rep 2018 Sep 21;8(1):14172 14 Citations |
1 | Adverse early life environment induces anxiety-like behavior and increases expression of FKBP5 mRNA splice variants in mouse brain. (Ke X, Fu Q, Majnik A, Cohen S, Liu Q, Lane R) Physiol Genomics 2018 Nov 01;50(11):973-981 18 Citations |
2 | Ceftriaxone Administration Disrupts Intestinal Homeostasis, Mediating Noninflammatory Proliferation and Dissemination of Commensal Enterococci. (Chakraborty R, Lam V, Kommineni S, Stromich J, Hayward M, Kristich CJ, Salzman NH) Infect Immun 2018 Dec;86(12) 27 Citations |
1 | Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism. (Benej M, Hong X, Vibhute S, Scott S, Wu J, Graves E, Le QT, Koong AC, Giaccia AJ, Yu B, Chen CS, Papandreou I, Denko NC) Proc Natl Acad Sci U S A 2018 Oct 16;115(42):10756-10761 113 Citations |
1 | Photoreceptor Survival Is Regulated by GSTO1-1 in the Degenerating Retina. (Fernando N, Wooff Y, Aggio-Bruce R, Chu-Tan JA, Jiao H, Dietrich C, Rutar M, Rooke M, Menon D, Eells JT, Valter K, Board PG, Provis J, Natoli R) Invest Ophthalmol Vis Sci 2018 Sep 04;59(11):4362-4374 6 Citations |
1 | GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism. (Tanimura N, Liao R, Wilson GM, Dent MR, Cao M, Burstyn JN, Hematti P, Liu X, Zhang Y, Zheng Y, Keles S, Xu J, Coon JJ, Bresnick EH) Dev Cell 2018 Sep 10;46(5):581-594.e4 29 Citations |
1 | The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity. (Swystun LL, Lai JD, Notley C, Georgescu I, Paine AS, Mewburn J, Nesbitt K, Schledzewski K, Géraud C, Kzhyshkowska J, Goerdt S, Hopman W, Montgomery RR, James PD, Lillicrap D) J Clin Invest 2018 Aug 31;128(9):4057-4073 57 Citations |
1 | Dysregulated Calcium Homeostasis in Cystic Fibrosis Neutrophils Leads to Deficient Antimicrobial Responses. (Robledo-Avila FH, Ruiz-Rosado JD, Brockman KL, Kopp BT, Amer AO, McCoy K, Bakaletz LO, Partida-Sanchez S) J Immunol 2018 Oct 01;201(7):2016-2027 36 Citations |
1 | Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration. (Himburg HA, Termini CM, Schlussel L, Kan J, Li M, Zhao L, Fang T, Sasine JP, Chang VY, Chute JP) Cell Stem Cell 2018 Sep 06;23(3):370-381.e5 84 Citations |
1 | Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD. (Reid CA, Nettesheim ER, Connor TB, Lipinski DM) Sci Rep 2018 Aug 06;8(1):11763 43 Citations |
4 | Frontline Science: PECAM-1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells. (Newman DK, Fu G, McOlash L, Schauder D, Newman PJ, Cui W, Rao S, Johnson BD, Gershan JA, Riese MJ) J Leukoc Biol 2018 Nov;104(5):883-893 14 Citations |
1 | PhoPR Contributes to Staphylococcus aureus Growth during Phosphate Starvation and Pathogenesis in an Environment-Specific Manner. (Kelliher JL, Radin JN, Kehl-Fie TE) Infect Immun 2018 Oct;86(10) 19 Citations |
2 | Liver X Receptors Suppress Activity of Cholesterol and Fatty Acid Synthesis Pathways To Oppose Gammaherpesvirus Replication. (Lange PT, Schorl C, Sahoo D, Tarakanova VL) mBio 2018 Jul 17;9(4) 19 Citations |
1 | CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia. (Pulikkan JA, Hegde M, Ahmad HM, Belaghzal H, Illendula A, Yu J, O'Hagan K, Ou J, Muller-Tidow C, Wolfe SA, Zhu LJ, Dekker J, Bushweller JH, Castilla LH) Cell 2018 Jun 28;174(1):172-186.e21 52 Citations |
1 | A novel combined ex vivo and in vivo lentiviral interleukin-10 gene delivery strategy at the time of transplantation decreases chronic lung allograft rejection in mice. (Oishi H, Juvet SC, Martinu T, Sato M, Medin JA, Liu M, Keshavjee S) J Thorac Cardiovasc Surg 2018 Sep;156(3):1305-1315 20 Citations |
1 | Asymmetric vasopressin signaling spatially organizes the master circadian clock. (Bedont JL, Rohr KE, Bathini A, Hattar S, Blackshaw S, Sehgal A, Evans JA) J Comp Neurol 2018 Sep 01;526(13):2048-2067 18 Citations |
1 | The Lateral Habenula Directs Coping Styles Under Conditions of Stress via Recruitment of the Endocannabinoid System. (Berger AL, Henricks AM, Lugo JM, Wright HR, Warrick CR, Sticht MA, Morena M, Bonilla I, Laredo SA, Craft RM, Parsons LH, Grandes PR, Hillard CJ, Hill MN, McLaughlin RJ) Biol Psychiatry 2018 Oct 15;84(8):611-623 34 Citations |
2 | mTORC1 and mTORC2 differentially promote natural killer cell development. (Yang C, Tsaih SW, Lemke A, Flister MJ, Thakar MS, Malarkannan S) Elife 2018 May 29;7 48 Citations |
1 | Cannabinoid CB2 receptors in the mouse brain: relevance for Alzheimer's disease. (López A, Aparicio N, Pazos MR, Grande MT, Barreda-Manso MA, Benito-Cuesta I, Vázquez C, Amores M, Ruiz-Pérez G, García-García E, Beatka M, Tolón RM, Dittel BN, Hillard CJ, Romero J) J Neuroinflammation 2018 May 24;15(1):158 91 Citations |
2 | Alcohol enhances symptoms and propensity for infection in inflammatory bowel disease patients and a murine model of DSS-induced colitis. (Cannon AR, Kuprys PV, Cobb AN, Ding X, Kothari AN, Kuo PC, Eberhardt JM, Hammer AM, Morris NL, Li X, Choudhry MA) J Leukoc Biol 2018 Sep;104(3):543-555 22 Citations |
1 | Bim regulates the survival and suppressive capability of CD8+ FOXP3+ regulatory T cells during murine GVHD. (Agle K, Vincent BG, Piper C, Belle L, Zhou V, Shlomchik W, Serody JS, Drobyski WR) Blood 2018 Jul 26;132(4):435-447 30 Citations |
3 | Wavelength-dependence of vasodilation and NO release from S-nitrosothiols and dinitrosyl iron complexes by far red/near infrared light. (Keszler A, Lindemer B, Hogg N, Weihrauch D, Lohr NL) Arch Biochem Biophys 2018 Jul 01;649:47-52 43 Citations |
1 | Neuraminidase 1 activates insulin receptor and reverses insulin resistance in obese mice. (Fougerat A, Pan X, Smutova V, Heveker N, Cairo CW, Issad T, Larrivée B, Medin JA, Pshezhetsky AV) Mol Metab 2018 Jun;12:76-88 44 Citations |
1 | Endothelial PPARγ (Peroxisome Proliferator-Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With Aging. (De Silva TM, Li Y, Kinzenbaw DA, Sigmund CD, Faraci FM) Hypertension 2018 Jul;72(1):227-234 29 Citations |
1 | An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABAA receptors. (Methuku KR, Li X, Cerne R, Gleason SD, Schkeryantz JM, Tiruveedhula VVNPB, Golani LK, Li G, Poe MM, Rahman MT, Cook JM, Fisher JL, Witkin JM) Pharmacol Biochem Behav 2018 Jul;170:9-13 14 Citations |
1 | Airway glycomic and allergic inflammatory consequences resulting from keratan sulfate galactose 6-O-sulfotransferase (CHST1) deficiency. (Kumagai T, Kiwamoto T, Brummet ME, Wu F, Aoki K, Zhu Z, Bochner BS, Tiemeyer M) Glycobiology 2018 Jun 01;28(6):406-417 8 Citations |
1 | Inflammatory Macrophage Expansion in Pulmonary Hypertension Depends upon Mobilization of Blood-Borne Monocytes. (Florentin J, Coppin E, Vasamsetti SB, Zhao J, Tai YY, Tang Y, Zhang Y, Watson A, Sembrat J, Rojas M, Vargas SO, Chan SY, Dutta P) J Immunol 2018 May 15;200(10):3612-3625 94 Citations |
1 | Activation of adenosine A2A or A2B receptors causes hypothermia in mice. (Carlin JL, Jain S, Duroux R, Suresh RR, Xiao C, Auchampach JA, Jacobson KA, Gavrilova O, Reitman ML) Neuropharmacology 2018 Sep 01;139:268-278 17 Citations |
1 | Intravenous administration of synthetic platelets (SynthoPlate) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis. (Dyer MR, Hickman D, Luc N, Haldeman S, Loughran P, Pawlowski C, Sen Gupta A, Neal MD) J Trauma Acute Care Surg 2018 Jun;84(6):917-923 35 Citations |
2 | Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors. (Pan P, Oshima K, Huang YW, Agle KA, Drobyski WR, Chen X, Zhang J, Yearsley MM, Yu J, Wang LS) Int J Cancer 2018 Aug 15;143(4):886-896 60 Citations |
2 | Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability. (Knutson DE, Kodali R, Divović B, Treven M, Stephen MR, Zahn NM, Dobričić V, Huber AT, Meirelles MA, Verma RS, Wimmer L, Witzigmann C, Arnold LA, Chiou LC, Ernst M, Mihovilovic MD, Savić MM, Sieghart W, Cook JM) J Med Chem 2018 Mar 22;61(6):2422-2446 33 Citations |
3 | Deactivation of 12(S)-HETE through (ω-1)-hydroxylation and β-oxidation in alternatively activated macrophages. (Kriska T, Thomas MJ, Falck JR, Campbell WB) J Lipid Res 2018 Apr;59(4):615-624 6 Citations |
1 | Cutting Edge: Check Your Mice-A Point Mutation in the Ncr1 Locus Identified in CD45.1 Congenic Mice with Consequences in Mouse Susceptibility to Infection. (Jang Y, Gerbec ZJ, Won T, Choi B, Podsiad A, B Moore B, Malarkannan S, Laouar Y) J Immunol 2018 Mar 15;200(6):1982-1987 24 Citations |
1 | Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis. (Zeng H, Yu M, Tan H, Li Y, Su W, Shi H, Dhungana Y, Guy C, Neale G, Cloer C, Peng J, Wang D, Chi H) Sci Adv 2018 Jan;4(1):eaar5701 30 Citations |
1 | Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA. (Dyer MR, Chen Q, Haldeman S, Yazdani H, Hoffman R, Loughran P, Tsung A, Zuckerbraun BS, Simmons RL, Neal MD) Sci Rep 2018 Feb 01;8(1):2068 125 Citations |
1 | Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiation. (Betts BC, Bastian D, Iamsawat S, Nguyen H, Heinrichs JL, Wu Y, Daenthanasanmak A, Veerapathran A, O'Mahony A, Walton K, Reff J, Horna P, Sagatys EM, Lee MC, Singer J, Chang YJ, Liu C, Pidala J, Anasetti C, Yu XZ) Proc Natl Acad Sci U S A 2018 Feb 13;115(7):1582-1587 58 Citations |
1 | Stat3 and CCAAT enhancer-binding protein β (C/ebpβ) activate Fanconi C gene transcription during emergency granulopoiesis. (Shah CA, Broglie L, Hu L, Bei L, Huang W, Dressler DB, Eklund EA) J Biol Chem 2018 Mar 16;293(11):3937-3948 7 Citations |
2 | Chronic stress alters adrenal clock function in a sexually dimorphic manner. (Stagl M, Bozsik M, Karow C, Wertz D, Kloehn I, Pillai S, Gasser PJ, Gilmartin MR, Evans JA) J Mol Endocrinol 2018 Feb;60(2):55-69 9 Citations |
1 | Negative allosteric modulation of alpha 5-containing GABAA receptors engenders antidepressant-like effects and selectively prevents age-associated hyperactivity in tau-depositing mice. (Xu NZ, Ernst M, Treven M, Cerne R, Wakulchik M, Li X, Jones TM, Gleason SD, Morrow D, Schkeryantz JM, Rahman MT, Li G, Poe MM, Cook JM, Witkin JM) Psychopharmacology (Berl) 2018 Apr;235(4):1151-1161 19 Citations |
2 | Elevated vasopressin in pregnant mice induces T-helper subset alterations consistent with human preeclampsia. (Scroggins SM, Santillan DA, Lund JM, Sandgren JA, Krotz LK, Hamilton WS, Devor EJ, Davis HA, Pierce GL, Gibson-Corley KN, Sigmund CD, Grobe JL, Santillan MK) Clin Sci (Lond) 2018 Feb 14;132(3):419-436 37 Citations |
1 | Phenotyping acute and chronic atopic dermatitis-like lesions in Stat6VT mice identifies a role for IL-33 in disease pathogenesis. (DaSilva-Arnold SC, Thyagarajan A, Seymour LJ, Yi Q, Bradish JR, Al-Hassani M, Zhou H, Perdue NJ, Nemeth V, Krbanjevic A, Serezani APM, Olson MR, Spandau DF, Travers JB, Kaplan MH, Turner MJ) Arch Dermatol Res 2018 Apr;310(3):197-207 8 Citations |
2 | Angiotensin AT1A receptors expressed in vasopressin-producing cells of the supraoptic nucleus contribute to osmotic control of vasopressin. (Sandgren JA, Linggonegoro DW, Zhang SY, Sapouckey SA, Claflin KE, Pearson NA, Leidinger MR, Pierce GL, Santillan MK, Gibson-Corley KN, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2018 Jun 01;314(6):R770-R780 30 Citations |
1 | Ac-SDKP decreases mortality and cardiac rupture after acute myocardial infarction. (Nakagawa P, Romero CA, Jiang X, D'Ambrosio M, Bordcoch G, Peterson EL, Harding P, Yang XP, Carretero OA) PLoS One 2018;13(1):e0190300 11 Citations |
1 | Telomerase reverse transcriptase protects against angiotensin II-induced microvascular endothelial dysfunction. (Ait-Aissa K, Kadlec AO, Hockenberry J, Gutterman DD, Beyer AM) Am J Physiol Heart Circ Physiol 2018 May 01;314(5):H1053-H1060 29 Citations |
1 | Macrophage Transitions in Heart Valve Development and Myxomatous Valve Disease. (Hulin A, Anstine LJ, Kim AJ, Potter SJ, DeFalco T, Lincoln J, Yutzey KE) Arterioscler Thromb Vasc Biol 2018 Mar;38(3):636-644 46 Citations |
1 | Overexpression of the neuronal human (pro)renin receptor mediates angiotensin II-independent blood pressure regulation in the central nervous system. (Peng H, Jensen DD, Li W, Sullivan MN, Buller SA, Worker CJ, Cooper SG, Zheng S, Earley S, Sigmund CD, Feng Y) Am J Physiol Heart Circ Physiol 2018 Mar 01;314(3):H580-H592 15 Citations |
1 | PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. (De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R) Proc Natl Acad Sci U S A 2018 Jan 30;115(5):E982-E991 52 Citations |
2 | Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling. (Moehring F, Cowie AM, Menzel AD, Weyer AD, Grzybowski M, Arzua T, Geurts AM, Palygin O, Stucky CL) Elife 2018 Jan 16;7 114 Citations |
1 | The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy. (McKenzie JA, Mbofung RM, Malu S, Zhang M, Ashkin E, Devi S, Williams L, Tieu T, Peng W, Pradeep S, Xu C, Zorro Manrique S, Liu C, Huang L, Chen Y, Forget MA, Haymaker C, Bernatchez C, Satani N, Muller F, Roszik J, Kalra A, Heffernan T, Sood A, Hu J, Amaria R, Davis RE, Hwu P) J Natl Cancer Inst 2018 Jul 01;110(7):777-786 60 Citations |
1 | Improvement of Photoreceptor Targeting via Intravitreal Delivery in Mouse and Human Retina Using Combinatory rAAV2 Capsid Mutant Vectors. (Reid CA, Ertel KJ, Lipinski DM) Invest Ophthalmol Vis Sci 2017 Dec 01;58(14):6429-6439 29 Citations |
1 | SNRK (Sucrose Nonfermenting 1-Related Kinase) Promotes Angiogenesis In Vivo. (Lu Q, Xie Z, Yan C, Ding Y, Ma Z, Wu S, Qiu Y, Cossette SM, Bordas M, Ramchandran R, Zou MH) Arterioscler Thromb Vasc Biol 2018 Feb;38(2):373-385 27 Citations |
1 | Developmental Stage-Specific Manifestations of Absent TPO/c-MPL Signalling in Newborn Mice. (Lorenz V, Ramsey H, Liu ZJ, Italiano J Jr, Hoffmeister K, Bihorel S, Mager D, Hu Z, Slayton WB, Kile BT, Sola-Visner M, Ferrer-Marin F) Thromb Haemost 2017 Dec;117(12):2322-2333 14 Citations |
1 | Multi-scale, multi-modal analysis uncovers complex relationship at the brain tissue-implant neural interface: new emphasis on the biological interface. (Michelson NJ, Vazquez AL, Eles JR, Salatino JW, Purcell EK, Williams JJ, Cui XT, Kozai TDY) J Neural Eng 2018 Jun;15(3):033001 91 Citations |
1 | Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas. (Todoric J, Antonucci L, Di Caro G, Li N, Wu X, Lytle NK, Dhar D, Banerjee S, Fagman JB, Browne CD, Umemura A, Valasek MA, Kessler H, Tarin D, Goggins M, Reya T, Diaz-Meco M, Moscat J, Karin M) Cancer Cell 2017 Dec 11;32(6):824-839.e8 95 Citations |
5 | PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development. (Yu M, Chen Y, Zeng H, Zheng Y, Fu G, Zhu W, Broeckel U, Aggarwal P, Turner A, Neale G, Guy C, Zhu N, Chi H, Wen R, Wang D) Nat Commun 2017 Nov 13;8(1):1457 26 Citations |
1 | CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response. (Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S) Cell Metab 2018 Jan 09;27(1):85-100.e8 170 Citations |
1 | Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin. (Verma AH, Richardson JP, Zhou C, Coleman BM, Moyes DL, Ho J, Huppler AR, Ramani K, McGeachy MJ, Mufazalov IA, Waisman A, Kane LP, Biswas PS, Hube B, Naglik JR, Gaffen SL) Sci Immunol 2017 Nov 03;2(17) 142 Citations |
1 | Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets. (Chen W, Druzak SA, Wang Y, Josephson CD, Hoffmeister KM, Ware J, Li R) Arterioscler Thromb Vasc Biol 2017 Dec;37(12):2271-2279 42 Citations |
1 | Acquisition of the Phosphate Transporter NptA Enhances Staphylococcus aureus Pathogenesis by Improving Phosphate Uptake in Divergent Environments. (Kelliher JL, Radin JN, Grim KP, Párraga Solórzano PK, Degnan PH, Kehl-Fie TE) Infect Immun 2018 Jan;86(1) 19 Citations |
1 | Corneal Mesenchymal Stromal Cells Are Directly Antiangiogenic via PEDF and sFLT-1. (Eslani M, Putra I, Shen X, Hamouie J, Afsharkhamseh N, Besharat S, Rosenblatt MI, Dana R, Hematti P, Djalilian AR) Invest Ophthalmol Vis Sci 2017 Oct 01;58(12):5507-5517 52 Citations |
1 | Contribution of Extra-Cardiac Cells in Murine Heart Valves is Age-Dependent. (Anstine LJ, Horne TE, Horwitz EM, Lincoln J) J Am Heart Assoc 2017 Oct 20;6(10) 21 Citations |
2 | Modulators of Enterococcus faecalis Cell Envelope Integrity and Antimicrobial Resistance Influence Stable Colonization of the Mammalian Gastrointestinal Tract. (Banla IL, Kommineni S, Hayward M, Rodrigues M, Palmer KL, Salzman NH, Kristich CJ) Infect Immun 2018 Jan;86(1) 21 Citations |
1 | Failure of Isoflurane Cardiac Preconditioning in Obese Type 2 Diabetic Mice Involves Aberrant Regulation of MicroRNA-21, Endothelial Nitric-oxide Synthase, and Mitochondrial Complex I. (Ge ZD, Li Y, Qiao S, Bai X, Warltier DC, Kersten JR, Bosnjak ZJ, Liang M) Anesthesiology 2018 Jan;128(1):117-129 14 Citations |
1 | The small-molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis. (Branchford BR, Stalker TJ, Law L, Acevedo G, Sather S, Brzezinski C, Wilson KM, Minson K, Lee-Sherick AB, Davizon-Castillo P, Ng C, Zhang W, Neeves KB, Lentz SR, Wang X, Frye SV, Shelton Earp H 3rd, DeRyckere D, Brass LF, Graham DK, Di Paola JA) J Thromb Haemost 2018 Feb;16(2):352-363 21 Citations |
1 | Inhibition of intestinal ascorbic acid uptake by lipopolysaccharide is mediated via transcriptional mechanisms. (Subramanian VS, Sabui S, Moradi H, Marchant JS, Said HM) Biochim Biophys Acta Biomembr 2018 Feb;1860(2):556-565 42 Citations |
1 | MRAP2 regulates ghrelin receptor signaling and hunger sensing. (Srisai D, Yin TC, Lee AA, Rouault AAJ, Pearson NA, Grobe JL, Sebag JA) Nat Commun 2017 Sep 28;8(1):713 52 Citations |
1 | Apolipoprotein A-I Modulates Atherosclerosis Through Lymphatic Vessel-Dependent Mechanisms in Mice. (Milasan A, Jean G, Dallaire F, Tardif JC, Merhi Y, Sorci-Thomas M, Martel C) J Am Heart Assoc 2017 Sep 22;6(9) 30 Citations |
3 | Red/near infrared light stimulates release of an endothelium dependent vasodilator and rescues vascular dysfunction in a diabetes model. (Keszler A, Lindemer B, Weihrauch D, Jones D, Hogg N, Lohr NL) Free Radic Biol Med 2017 Dec;113:157-164 30 Citations |
1 | Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele. (Wu J, Liu X, Nayak SG, Pitarresi JR, Cuitiño MC, Yu L, Hildreth BE 3rd, Thies KA, Schilling DJ, Fernandez SA, Leone G, Ostrowski MC) PLoS One 2017;12(9):e0184984 14 Citations |
1 | Factor V Leiden is associated with increased sperm count. (van Mens TE, Joensen UN, Bochdanovits Z, Takizawa A, Peter J, Jørgensen N, Szecsi PB, Meijers JCM, Weiler H, Rajpert-De Meyts E, Repping S, Middeldorp S) Hum Reprod 2017 Nov 01;32(11):2332-2339 2 Citations |
2 | T Cells Deficient in Diacylglycerol Kinase ζ Are Resistant to PD-1 Inhibition and Help Create Persistent Host Immunity to Leukemia. (Jing W, Gershan JA, Holzhauer S, Weber J, Palen K, McOlash L, Pulakanti K, Wesley E, Rao S, Johnson BD, Riese MJ) Cancer Res 2017 Oct 15;77(20):5676-5686 14 Citations |
1 | PD-1 Status in CD8+ T Cells Associates with Survival and Anti-PD-1 Therapeutic Outcomes in Head and Neck Cancer. (Kansy BA, Concha-Benavente F, Srivastava RM, Jie HB, Shayan G, Lei Y, Moskovitz J, Moy J, Li J, Brandau S, Lang S, Schmitt NC, Freeman GJ, Gooding WE, Clump DA, Ferris RL) Cancer Res 2017 Nov 15;77(22):6353-6364 145 Citations |
1 | Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition. (Nazir S, Gadi I, Al-Dabet MM, Elwakiel A, Kohli S, Ghosh S, Manoharan J, Ranjan S, Bock F, Braun-Dullaeus RC, Esmon CT, Huber TB, Camerer E, Dockendorff C, Griffin JH, Isermann B, Shahzad K) Blood 2017 Dec 14;130(24):2664-2677 128 Citations |
1 | Natural immunoglobulin M initiates an inflammatory response important for both hepatic ischemia reperfusion injury and regeneration in mice. (Marshall K, Jin J, Atkinson C, Alawieh A, Qiao F, Lei B, Chavin KD, He S, Tomlinson S) Hepatology 2018 Feb;67(2):721-735 26 Citations |
1 | Soluble interleukin-13rα1: a circulating regulator of glucose. (Rachmin I, O'Meara CC, Ricci-Blair EM, Feng Y, Christensen EM, Duffy JF, Zitting KM, Czeisler CA, Pancoast JR, Cannon CP, O'Donoghue ML, Morrow DA, Lee RT) Am J Physiol Endocrinol Metab 2017 Dec 01;313(6):E663-E671 4 Citations |
1 | Distinct effects of estrogen receptor antagonism on object recognition and spatial memory consolidation in ovariectomized mice. (Kim J, Frick KM) Psychoneuroendocrinology 2017 Nov;85:110-114 29 Citations |
2 | Single-Immunoglobulin Interleukin-1-Related Receptor regulates vulnerability to TLR4-mediated necrotizing enterocolitis in a mouse model. (Fawley J, Cuna A, Menden HL, McElroy S, Umar S, Welak SR, Gourlay DM, Li X, Sampath V) Pediatr Res 2018 Jan;83(1-1):164-174 26 Citations |
1 | Contribution of amygdala CRF neurons to chronic pain. (Andreoli M, Marketkar T, Dimitrov E) Exp Neurol 2017 Dec;298(Pt A):1-12 39 Citations |
1 | Platelets reduce anoikis and promote metastasis by activating YAP1 signaling. (Haemmerle M, Taylor ML, Gutschner T, Pradeep S, Cho MS, Sheng J, Lyons YM, Nagaraja AS, Dood RL, Wen Y, Mangala LS, Hansen JM, Rupaimoole R, Gharpure KM, Rodriguez-Aguayo C, Yim SY, Lee JS, Ivan C, Hu W, Lopez-Berestein G, Wong ST, Karlan BY, Levine DA, Liu J, Afshar-Kharghan V, Sood AK) Nat Commun 2017 Aug 21;8(1):310 162 Citations |
1 | Neurobiological correlates of state-dependent context fear. (Meyer MAA, Corcoran KA, Chen HJ, Gallego S, Li G, Tiruveedhula VV, Cook JM, Radulovic J) Learn Mem 2017 Sep;24(9):385-391 13 Citations |
1 | Immune tolerance induced by platelet-targeted factor VIII gene therapy in hemophilia A mice is CD4 T cell mediated. (Chen Y, Luo X, Schroeder JA, Chen J, Baumgartner CK, Hu J, Shi Q) J Thromb Haemost 2017 Oct;15(10):1994-2004 25 Citations |
1 | Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. (Patterson M, Barske L, Van Handel B, Rau CD, Gan P, Sharma A, Parikh S, Denholtz M, Huang Y, Yamaguchi Y, Shen H, Allayee H, Crump JG, Force TI, Lien CL, Makita T, Lusis AJ, Kumar SR, Sucov HM) Nat Genet 2017 Sep;49(9):1346-1353 218 Citations |
1 | Neural stem cell mediated recovery is enhanced by Chondroitinase ABC pretreatment in chronic cervical spinal cord injury. (Suzuki H, Ahuja CS, Salewski RP, Li L, Satkunendrarajah K, Nagoshi N, Shibata S, Fehlings MG) PLoS One 2017;12(8):e0182339 75 Citations |
2 | Versican-Derived Matrikines Regulate Batf3-Dendritic Cell Differentiation and Promote T Cell Infiltration in Colorectal Cancer. (Hope C, Emmerich PB, Papadas A, Pagenkopf A, Matkowskyj KA, Van De Hey DR, Payne SN, Clipson L, Callander NS, Hematti P, Miyamoto S, Johnson MG, Deming DA, Asimakopoulos F) J Immunol 2017 Sep 01;199(5):1933-1941 70 Citations |
1 | Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease. (Bradford EM, Ryu SH, Singh AP, Lee G, Goretsky T, Sinh P, Williams DB, Cloud AL, Gounaris E, Patel V, Lamping OF, Lynch EB, Moyer MP, De Plaen IG, Shealy DJ, Yang GY, Barrett TA) J Immunol 2017 Sep 01;199(5):1886-1897 94 Citations |
1 | Thrombin promotes diet-induced obesity through fibrin-driven inflammation. (Kopec AK, Abrahams SR, Thornton S, Palumbo JS, Mullins ES, Divanovic S, Weiler H, Owens AP 3rd, Mackman N, Goss A, van Ryn J, Luyendyk JP, Flick MJ) J Clin Invest 2017 Aug 01;127(8):3152-3166 86 Citations |
1 | ATM supports gammaherpesvirus replication by attenuating type I interferon pathway. (Darrah EJ, Stoltz KP, Ledwith M, Tarakanova VL) Virology 2017 Oct;510:137-146 4 Citations |
1 | B Cell-Specific Expression of Ataxia-Telangiectasia Mutated Protein Kinase Promotes Chronic Gammaherpesvirus Infection. (Darrah EJ, Kulinski JM, Mboko WP, Xin G, Malherbe LP, Gauld SB, Cui W, Tarakanova VL) J Virol 2017 Oct 01;91(19) 7 Citations |
1 | Thermoneutrality but Not UCP1 Deficiency Suppresses Monocyte Mobilization Into Blood. (Williams JW, Elvington A, Ivanov S, Kessler S, Luehmann H, Baba O, Saunders BT, Kim KW, Johnson MW, Craft CS, Choi JH, Sorci-Thomas MG, Zinselmeyer BH, Brestoff JR, Liu Y, Randolph GJ) Circ Res 2017 Sep 01;121(6):662-676 33 Citations |
1 | Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications. (Zhang G, Cheng J, McCorvy JD, Lorello PJ, Caldarone BJ, Roth BL, Kozikowski AP) J Med Chem 2017 Jul 27;60(14):6273-6288 18 Citations |
1 | Adoptive cell therapy using PD-1+ myeloma-reactive T cells eliminates established myeloma in mice. (Jing W, Gershan JA, Blitzer GC, Palen K, Weber J, McOlash L, Riese M, Johnson BD) J Immunother Cancer 2017;5:51 22 Citations |
2 | Cardiotonic Steroids Stimulate Macrophage Inflammatory Responses Through a Pathway Involving CD36, TLR4, and Na/K-ATPase. (Chen Y, Huang W, Yang M, Xin G, Cui W, Xie Z, Silverstein RL) Arterioscler Thromb Vasc Biol 2017 Aug;37(8):1462-1469 21 Citations |
1 | miRNA-mediated post-transcriptional silencing of transgenes leads to increased adeno-associated viral vector yield and targeting specificity. (Reid CA, Boye SL, Hauswirth WW, Lipinski DM) Gene Ther 2017 Aug;24(8):462-469 10 Citations |
1 | Exosome-Derived miR-25-3p and miR-92a-3p Stimulate Liposarcoma Progression. (Casadei L, Calore F, Creighton CJ, Guescini M, Batte K, Iwenofu OH, Zewdu A, Braggio DA, Bill KL, Fadda P, Lovat F, Lopez G, Gasparini P, Chen JL, Kladney RD, Leone G, Lev D, Croce CM, Pollock RE) Cancer Res 2017 Jul 15;77(14):3846-3856 143 Citations |
1 | HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease. (Chandrashekaran V, Seth RK, Dattaroy D, Alhasson F, Ziolenka J, Carson J, Berger FG, Kalyanaraman B, Diehl AM, Chatterjee S) Redox Biol 2017 Oct;13:8-19 49 Citations |
1 | PDE4 Inhibition Restores the Balance Between Excitation and Inhibition in VTA Dopamine Neurons Disrupted by Repeated In Vivo Cocaine Exposure. (Liu X, Zhong P, Vickstrom C, Li Y, Liu QS) Neuropsychopharmacology 2017 Sep;42(10):1991-1999 15 Citations |
2 | Evidence for intraventricular secretion of angiotensinogen and angiotensin by the subfornical organ using transgenic mice. (Agassandian K, Grobe JL, Liu X, Agassandian M, Thompson AP, Sigmund CD, Cassell MD) Am J Physiol Regul Integr Comp Physiol 2017 Jun 01;312(6):R973-R981 10 Citations |
1 | Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets. (Sladojevic N, Oh GT, Kim HH, Beaulieu LM, Falet H, Kaminski K, Freedman JE, Liao JK) Cardiovasc Res 2017 Sep 01;113(11):1307-1317 19 Citations |
1 | The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice. (Fenske RJ, Cadena MT, Harenda QE, Wienkes HN, Carbajal K, Schaid MD, Laundre E, Brill AL, Truchan NA, Brar H, Wisinski J, Cai J, Graham TE, Engin F, Kimple ME) Endocrinology 2017 Jun 01;158(6):1645-1658 16 Citations |
1 | Mitochondrial Cx43 hemichannels contribute to mitochondrial calcium entry and cell death in the heart. (Gadicherla AK, Wang N, Bulic M, Agullo-Pascual E, Lissoni A, De Smet M, Delmar M, Bultynck G, Krysko DV, Camara A, Schlüter KD, Schulz R, Kwok WM, Leybaert L) Basic Res Cardiol 2017 May;112(3):27 97 Citations |
1 | Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH), a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist. (Jensen AA, McCorvy JD, Leth-Petersen S, Bundgaard C, Liebscher G, Kenakin TP, Bräuner-Osborne H, Kehler J, Kristensen JL) J Pharmacol Exp Ther 2017 Jun;361(3):441-453 43 Citations |
3 | Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice. (Weihrauch D, Krolikowski JG, Jones DW, Zaman T, Bamkole O, Struve J, Pagel PS, Lohr NL, Pritchard KA Jr) J Vis Exp 2017 Mar 24(121) 1 Citation |
1 | Retinol-binding protein 7 is an endothelium-specific PPARγ cofactor mediating an antioxidant response through adiponectin. (Hu C, Keen HL, Lu KT, Liu X, Wu J, Davis DR, Ibeawuchi SC, Vogel S, Quelle FW, Sigmund CD) JCI Insight 2017 Mar 23;2(6):e91738 25 Citations |
1 | Cos2/Kif7 and Osm-3/Kif17 regulate onset of outer segment development in zebrafish photoreceptors through distinct mechanisms. (Lewis TR, Kundinger SR, Pavlovich AL, Bostrom JR, Link BA, Besharse JC) Dev Biol 2017 May 15;425(2):176-190 19 Citations |
1 | Identification of a novel, fast-acting GABAergic antidepressant. (McMurray KMJ, Ramaker MJ, Barkley-Levenson AM, Sidhu PS, Elkin PK, Reddy MK, Guthrie ML, Cook JM, Rawal VH, Arnold LA, Dulawa SC, Palmer AA) Mol Psychiatry 2018 Feb;23(2):384-391 29 Citations |
2 | Pharmacological and antihyperalgesic properties of the novel α2/3 preferring GABAA receptor ligand MP-III-024. (Fischer BD, Schlitt RJ, Hamade BZ, Rehman S, Ernst M, Poe MM, Li G, Kodali R, Arnold LA, Cook JM) Brain Res Bull 2017 May;131:62-69 22 Citations |
1 | Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism. (Claflin KE, Sandgren JA, Lambertz AM, Weidemann BJ, Littlejohn NK, Burnett CM, Pearson NA, Morgan DA, Gibson-Corley KN, Rahmouni K, Grobe JL) J Clin Invest 2017 Apr 03;127(4):1414-1424 56 Citations |
1 | TRPV4 ion channel is a novel regulator of dermal myofibroblast differentiation. (Sharma S, Goswami R, Merth M, Cohen J, Lei KY, Zhang DX, Rahaman SO) Am J Physiol Cell Physiol 2017 May 01;312(5):C562-C572 50 Citations |
1 | The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons. (Tong J, Liu X, Vickstrom C, Li Y, Yu L, Lu Y, Smrcka AV, Liu QS) J Neurosci 2017 Mar 15;37(11):3030-3044 21 Citations |
4 | Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling. (Dong L, Yuan Y, Opansky C, Chen Y, Aguilera-Barrantes I, Wu S, Yuan R, Cao Q, Cheng YC, Sahoo D, Silverstein RL, Ren B) Oncotarget 2017 Apr 04;8(14):22550-22562 28 Citations |
1 | Augmentation of Muscle Blood Flow by Ultrasound Cavitation Is Mediated by ATP and Purinergic Signaling. (Belcik JT, Davidson BP, Xie A, Wu MD, Yadava M, Qi Y, Liang S, Chon CR, Ammi AY, Field J, Harmann L, Chilian WM, Linden J, Lindner JR) Circulation 2017 Mar 28;135(13):1240-1252 82 Citations |
1 | DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis. (Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, Engelke DR, Kaplan MJ, Markovitz DM) Nat Commun 2017 Feb 06;8:14252 73 Citations |
1 | Modification of host dendritic cells by microchimerism-derived extracellular vesicles generates split tolerance. (Bracamonte-Baran W, Florentin J, Zhou Y, Jankowska-Gan E, Haynes WJ, Zhong W, Brennan TV, Dutta P, Claas FH, van Rood JJ, Burlingham WJ) Proc Natl Acad Sci U S A 2017 Jan 31;114(5):1099-1104 54 Citations |
1 | Testing the Efficacy of Contrast-Enhanced Ultrasound in Detecting Transplant Rejection Using a Murine Model of Heart Transplantation. (Fischer K, Ohori S, Meral FC, Uehara M, Giannini S, Ichimura T, Smith RN, Jolesz FA, Guleria I, Zhang Y, White PJ, McDannold NJ, Hoffmeister K, Givertz MM, Abdi R) Am J Transplant 2017 Jul;17(7):1791-1801 12 Citations |
1 | Combined chondroitinase and KLF7 expression reduce net retraction of sensory and CST axons from sites of spinal injury. (Wang Z, Winsor K, Nienhaus C, Hess E, Blackmore MG) Neurobiol Dis 2017 Mar;99:24-35 30 Citations |
1 | Dual Specificity Phosphatase 5 Is Essential for T Cell Survival. (Kutty RG, Xin G, Schauder DM, Cossette SM, Bordas M, Cui W, Ramchandran R) PLoS One 2016;11(12):e0167246 15 Citations |
2 | Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion. (Jalan-Sakrikar N, De Assuncao TM, Lu J, Almada LL, Lomberk G, Fernandez-Zapico ME, Urrutia R, Huebert RC) PLoS One 2016;11(12):e0168266 14 Citations |
1 | Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning. (Taniguchi K, Anderson AE, Melhuish TA, Carlton AL, Manukyan A, Sutherland AE, Wotton D) Eur J Hum Genet 2017 Feb;25(2):208-215 15 Citations |
2 | Hypothermia in mouse is caused by adenosine A1 and A3 receptor agonists and AMP via three distinct mechanisms. (Carlin JL, Jain S, Gizewski E, Wan TC, Tosh DK, Xiao C, Auchampach JA, Jacobson KA, Gavrilova O, Reitman ML) Neuropharmacology 2017 Mar 01;114:101-113 53 Citations |
1 | Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats. (Lehto SG, Weyer AD, Youngblood BD, Zhang M, Yin R, Wang W, Teffera Y, Cooke M, Stucky CL, Schenkel L, Geuns-Meyer S, Moyer BD, Wild KD, Gavva NR) Mol Pain 2016;12 24 Citations |
1 | Impact of the gut microbiota on enhancer accessibility in gut intraepithelial lymphocytes. (Semenkovich NP, Planer JD, Ahern PP, Griffin NW, Lin CY, Gordon JI) Proc Natl Acad Sci U S A 2016 Dec 20;113(51):14805-14810 31 Citations |
1 | Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. (Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG) Proc Natl Acad Sci U S A 2016 Dec 13;113(50):E8178-E8186 104 Citations |
1 | TRPV4 ION Channel Is Associated with Scleroderma. (Goswami R, Cohen J, Sharma S, Zhang DX, Lafyatis R, Bhawan J, Rahaman SO) J Invest Dermatol 2017 Apr;137(4):962-965 20 Citations |
1 | Cullin-3 mutation causes arterial stiffness and hypertension through a vascular smooth muscle mechanism. (Agbor LN, Ibeawuchi SC, Hu C, Wu J, Davis DR, Keen HL, Quelle FW, Sigmund CD) JCI Insight 2016 Nov 17;1(19):e91015 50 Citations |
1 | Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo. (De Silva SR, Charbel Issa P, Singh MS, Lipinski DM, Barnea-Cramer AO, Walker NJ, Barnard AR, Hankins MW, MacLaren RE) Gene Ther 2016 Nov;23(11):767-774 24 Citations |
1 | Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration. (Yan X, Himburg HA, Pohl K, Quarmyne M, Tran E, Zhang Y, Fang T, Kan J, Chao NJ, Zhao L, Doan PL, Chute JP) Cell Rep 2016 Nov 01;17(6):1584-1594 20 Citations |
1 | Superoxide Dismutase 3 R213G Single-Nucleotide Polymorphism Blocks Murine Bleomycin-Induced Fibrosis and Promotes Resolution of Inflammation. (Mouradian GC, Gaurav R, Pugliese S, El Kasmi K, Hartman B, Hernandez-Lagunas L, Stenmark KR, Bowler RP, Nozik-Grayck E) Am J Respir Cell Mol Biol 2017 Mar;56(3):362-371 26 Citations |
1 | Cardiac-deleterious role of galectin-3 in chronic angiotensin II-induced hypertension. (González GE, Rhaleb NE, D'Ambrosio MA, Nakagawa P, Liao TD, Peterson EL, Leung P, Dai X, Janic B, Liu YH, Yang XP, Carretero OA) Am J Physiol Heart Circ Physiol 2016 Nov 01;311(5):H1287-H1296 54 Citations |
1 | Interferon Regulatory Factor 1 and Type I Interferon Cooperate To Control Acute Gammaherpesvirus Infection. (Mboko WP, Rekow MM, Ledwith MP, Lange PT, Schmitz KE, Anderson S, Tarakanova VL) J Virol 2017 Jan 01;91(1) 18 Citations |
1 | Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice. (Lin B, Ciecko AE, MacKinney E, Serreze DV, Chen YG) Immunogenetics 2017 Mar;69(3):193-198 2 Citations |
1 | Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle. (De La Fuente S, Fernandez-Sanz C, Vail C, Agra EJ, Holmstrom K, Sun J, Mishra J, Williams D, Finkel T, Murphy E, Joseph SK, Sheu SS, Csordás G) J Biol Chem 2016 Oct 28;291(44):23343-23362 47 Citations |
1 | High endogenous activated protein C levels attenuates bleomycin-induced pulmonary fibrosis. (Lin C, von der Thüsen J, Isermann B, Weiler H, van der Poll T, Borensztajn K, Spek CA) J Cell Mol Med 2016 Nov;20(11):2029-2035 11 Citations |
1 | Adverse early life environment increases hippocampal microglia abundance in conjunction with decreased neural stem cells in juvenile mice. (Cohen S, Ke X, Liu Q, Fu Q, Majnik A, Lane R) Int J Dev Neurosci 2016 Dec;55:56-65 24 Citations |
1 | A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis. (Xu S, Liu B, Yin M, Koroleva M, Mastrangelo M, Ture S, Morrell CN, Zhang DX, Fisher EA, Jin ZG) Oncotarget 2016 Jun 21;7(25):37622-37635 54 Citations |
2 | Selective Deletion of the Brain-Specific Isoform of Renin Causes Neurogenic Hypertension. (Shinohara K, Liu X, Morgan DA, Davis DR, Sequeira-Lopez ML, Cassell MD, Grobe JL, Rahmouni K, Sigmund CD) Hypertension 2016 Dec;68(6):1385-1392 42 Citations |
1 | CD36 Provides Host Protection Against Klebsiella pneumoniae Intrapulmonary Infection by Enhancing Lipopolysaccharide Responsiveness and Macrophage Phagocytosis. (Olonisakin TF, Li H, Xiong Z, Kochman EJ, Yu M, Qu Y, Hulver M, Kolls JK, St Croix C, Doi Y, Nguyen MH, Shanks RM, Mallampalli RK, Kagan VE, Ray A, Silverstein RL, Ray P, Lee JS) J Infect Dis 2016 Dec 15;214(12):1865-1875 24 Citations |
1 | Organic cation transporter 3 (OCT3) is localized to intracellular and surface membranes in select glial and neuronal cells within the basolateral amygdaloid complex of both rats and mice. (Gasser PJ, Hurley MM, Chan J, Pickel VM) Brain Struct Funct 2017 May;222(4):1913-1928 39 Citations |
1 | Role of CaMKII in Ang-II-dependent small artery remodeling. (Prasad AM, Ketsawatsomkron P, Nuno DW, Koval OM, Dibbern ME, Venema AN, Sigmund CD, Lamping KG, Grumbach IM) Vascul Pharmacol 2016 Dec;87:172-179 5 Citations |
1 | Genetic ablation of Smoothened in pancreatic fibroblasts increases acinar-ductal metaplasia. (Liu X, Pitarresi JR, Cuitiño MC, Kladney RD, Woelke SA, Sizemore GM, Nayak SG, Egriboz O, Schweickert PG, Yu L, Trela S, Schilling DJ, Halloran SK, Li M, Dutta S, Fernandez SA, Rosol TJ, Lesinski GB, Shakya R, Ludwig T, Konieczny SF, Leone G, Wu J, Ostrowski MC) Genes Dev 2016 Sep 01;30(17):1943-55 46 Citations |
2 | Corticosterone Potentiation of Cocaine-Induced Reinstatement of Conditioned Place Preference in Mice is Mediated by Blockade of the Organic Cation Transporter 3. (McReynolds JR, Taylor A, Vranjkovic O, Ambrosius T, Derricks O, Nino B, Kurtoglu B, Wheeler RA, Baker DA, Gasser PJ, Mantsch JR) Neuropsychopharmacology 2017 Feb;42(3):757-765 23 Citations |
1 | Structure-based discovery of opioid analgesics with reduced side effects. (Manglik A, Lin H, Aryal DK, McCorvy JD, Dengler D, Corder G, Levit A, Kling RC, Bernat V, Hübner H, Huang XP, Sassano MF, Giguère PM, Löber S, Da Duan, Scherrer G, Kobilka BK, Gmeiner P, Roth BL, Shoichet BK) Nature 2016 Sep 08;537(7619):185-190 677 Citations |
1 | Glucokinase expression is regulated by glucose through O-GlcNAc glycosylation. (Baldini SF, Steenackers A, Olivier-Van Stichelen S, Mir AM, Mortuaire M, Lefebvre T, Guinez C) Biochem Biophys Res Commun 2016 Sep 16;478(2):942-8 30 Citations |
1 | Obesity alters immune and metabolic profiles: New insight from obese-resistant mice on high-fat diet. (Boi SK, Buchta CM, Pearson NA, Francis MB, Meyerholz DK, Grobe JL, Norian LA) Obesity (Silver Spring) 2016 Oct;24(10):2140-9 51 Citations |
1 | Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema. (Stanley SE, Gable DL, Wagner CL, Carlile TM, Hanumanthu VS, Podlevsky JD, Khalil SE, DeZern AE, Rojas-Duran MF, Applegate CD, Alder JK, Parry EM, Gilbert WV, Armanios M) Sci Transl Med 2016 Aug 10;8(351):351ra107 150 Citations |
4 | A colitogenic memory CD4+ T cell population mediates gastrointestinal graft-versus-host disease. (Zhou V, Agle K, Chen X, Beres A, Komorowski R, Belle L, Taylor C, Zhu F, Haribhai D, Williams CB, Verbsky J, Blumenschein W, Sadekova S, Bowman E, Ballantyne C, Weaver C, Serody DA, Vincent B, Serody J, Cua DJ, Drobyski WR) J Clin Invest 2016 Sep 01;126(9):3541-55 26 Citations |
3 | Targeting factor VIII expression to platelets for hemophilia A gene therapy does not induce an apparent thrombotic risk in mice. (Baumgartner CK, Mattson JG, Weiler H, Shi Q, Montgomery RR) J Thromb Haemost 2017 Jan;15(1):98-109 16 Citations |
1 | Aged Human Stored Red Blood Cell Supernatant Inhibits Macrophage Phagocytosis in an HMGB1 Dependent Manner After Trauma in a Murine Model. (Zettel KR, Dyer M, Raval JS, Wu X, Klune JR, Gutierrez A, Triulzi DJ, Billiar TR, Neal MD) Shock 2017 Feb;47(2):217-224 10 Citations |
1 | Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis. (Cheng HY, Gaddis DE, Wu R, McSkimming C, Haynes LD, Taylor AM, McNamara CA, Sorci-Thomas M, Hedrick CC) J Clin Invest 2016 Sep 01;126(9):3236-46 55 Citations |
1 | Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche. (Miranda F, Mannion D, Liu S, Zheng Y, Mangala LS, Redondo C, Herrero-Gonzalez S, Xu R, Taylor C, Chedom DF, Carrami EM, Albukhari A, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Salah E, Abdul Azeez KR, Elkins JM, Campo L, Myers KA, Klotz D, Bivona S, Dhar S, Bast RC Jr, Saya H, Choi HG, Gray NS, Fischer R, Kessler BM, Yau C, Sood AK, Motohara T, Knapp S, Ahmed AA) Cancer Cell 2016 Aug 08;30(2):273-289 132 Citations |
2 | Suppression of Resting Metabolism by the Angiotensin AT2 Receptor. (Littlejohn NK, Keen HL, Weidemann BJ, Claflin KE, Tobin KV, Markan KR, Park S, Naber MC, Gourronc FA, Pearson NA, Liu X, Morgan DA, Klingelhutz AJ, Potthoff MJ, Rahmouni K, Sigmund CD, Grobe JL) Cell Rep 2016 Aug 09;16(6):1548-1560 36 Citations |
1 | Characterization of Fatty Acid Binding Protein 7 (FABP7) in the Murine Retina. (Su X, Tan QS, Parikh BH, Tan A, Mehta MN, Sia Wey Y, Tun SB, Li LJ, Han XY, Wong TY, Hunziker W, Luu CD, Owada Y, Barathi VA, Zhang SS, Chaurasia SS) Invest Ophthalmol Vis Sci 2016 Jun 01;57(7):3397-408 12 Citations |
1 | Identification and characterization of the elusive mutation causing the historical von Willebrand Disease type IIC Miami. (Obser T, Ledford-Kraemer M, Oyen F, Brehm MA, Denis CV, Marschalek R, Montgomery RR, Sadler JE, Schneppenheim S, Budde U, Schneppenheim R) J Thromb Haemost 2016 Sep;14(9):1725-35 9 Citations |
1 | Fatty acid amide hydrolase inhibition for the symptomatic relief of Parkinson's disease. (Celorrio M, Fernández-Suárez D, Rojo-Bustamante E, Echeverry-Alzate V, Ramírez MJ, Hillard CJ, López-Moreno JA, Maldonado R, Oyarzábal J, Franco R, Aymerich MS) Brain Behav Immun 2016 Oct;57:94-105 51 Citations |
1 | Pancreatic β-Cells From Mice Offset Age-Associated Mitochondrial Deficiency With Reduced KATP Channel Activity. (Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ) Diabetes 2016 Sep;65(9):2700-10 51 Citations |
1 | A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells. (Goetz B, An W, Mohapatra B, Zutshi N, Iseka F, Storck MD, Meza J, Sheinin Y, Band V, Band H) Oncotarget 2016 Aug 09;7(32):51107-51123 8 Citations |
2 | mTORC1 Signaling Contributes to Drinking But Not Blood Pressure Responses to Brain Angiotensin II. (Muta K, Morgan DA, Grobe JL, Sigmund CD, Rahmouni K) Endocrinology 2016 Aug;157(8):3140-8 9 Citations |
1 | Optogenetic Interrogation of Functional Synapse Formation by Corticospinal Tract Axons in the Injured Spinal Cord. (Jayaprakash N, Wang Z, Hoeynck B, Krueger N, Kramer A, Balle E, Wheeler DS, Wheeler RA, Blackmore MG) J Neurosci 2016 May 25;36(21):5877-90 41 Citations |
1 | Inhibition of myeloperoxidase oxidant production by N-acetyl lysyltyrosylcysteine amide reduces brain damage in a murine model of stroke. (Yu G, Liang Y, Huang Z, Jones DW, Pritchard KA Jr, Zhang H) J Neuroinflammation 2016 May 24;13(1):119 52 Citations |
6 | Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells. (Cheng G, Zielonka J, Ouari O, Lopez M, McAllister D, Boyle K, Barrios CS, Weber JJ, Johnson BD, Hardy M, Dwinell MB, Kalyanaraman B) Cancer Res 2016 Jul 01;76(13):3904-15 153 Citations |
1 | Tgif1 and Tgif2 Regulate Axial Patterning in Mouse. (Melhuish TA, Taniguchi K, Wotton D) PLoS One 2016;11(5):e0155837 7 Citations |
1 | Inhibition of local estrogen synthesis in the hippocampus impairs hippocampal memory consolidation in ovariectomized female mice. (Tuscher JJ, Szinte JS, Starrett JR, Krentzel AA, Fortress AM, Remage-Healey L, Frick KM) Horm Behav 2016 Jul;83:60-67 98 Citations |
1 | Adhesion of Blood Clots Can Be Enhanced When Copolymerized with a Macromer That Is Crosslinked by Coagulation Factor XIIIa. (Chan KY, Zhao C, Siren EM, Chan JC, Boschman J, Kastrup CJ) Biomacromolecules 2016 Jun 13;17(6):2248-52 11 Citations |
1 | Arginase-1 is expressed exclusively by infiltrating myeloid cells in CNS injury and disease. (Greenhalgh AD, Passos Dos Santos R, Zarruk JG, Salmon CK, Kroner A, David S) Brain Behav Immun 2016 Aug;56:61-7 53 Citations |
1 | Intracellular Trafficking, Localization, and Mobilization of Platelet-Borne Thiol Isomerases. (Crescente M, Pluthero FG, Li L, Lo RW, Walsh TG, Schenk MP, Holbrook LM, Louriero S, Ali MS, Vaiyapuri S, Falet H, Jones IM, Poole AW, Kahr WH, Gibbins JM) Arterioscler Thromb Vasc Biol 2016 Jun;36(6):1164-73 47 Citations |
1 | Neonatal growth restriction-related leptin deficiency enhances leptin-triggered sympathetic activation and central angiotensin II receptor-dependent stress-evoked hypertension. (Peotta V, Rahmouni K, Segar JL, Morgan DA, Pitz KM, Rice OM, Roghair RD) Pediatr Res 2016 Aug;80(2):244-51 5 Citations |
3 | An IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin Mice. (Weihrauch D, Krolikowski JG, Jones DW, Zaman T, Bamkole O, Struve J, Pillai S, Pagel PS, Lohr NL, Pritchard KA Jr) PLoS One 2016;11(4):e0151999 9 Citations |
2 | Modeling Hematopoiesis and Responses to Radiation Countermeasures in a Bone Marrow-on-a-Chip. (Torisawa YS, Mammoto T, Jiang E, Jiang A, Mammoto A, Watters AL, Bahinski A, Ingber DE) Tissue Eng Part C Methods 2016 May;22(5):509-15 49 Citations |
1 | 17β-Estradiol and Agonism of G-protein-Coupled Estrogen Receptor Enhance Hippocampal Memory via Different Cell-Signaling Mechanisms. (Kim J, Szinte JS, Boulware MI, Frick KM) J Neurosci 2016 Mar 16;36(11):3309-21 108 Citations |
2 | Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes. (Zappia KJ, Garrison SR, Palygin O, Weyer AD, Barabas ME, Lawlor MW, Staruschenko A, Stucky CL) PLoS One 2016;11(3):e0151602 23 Citations |
1 | Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk. (Zhu W, Gregory JC, Org E, Buffa JA, Gupta N, Wang Z, Li L, Fu X, Wu Y, Mehrabian M, Sartor RB, McIntyre TM, Silverstein RL, Tang WHW, DiDonato JA, Brown JM, Lusis AJ, Hazen SL) Cell 2016 Mar 24;165(1):111-124 1305 Citations |
1 | The anti-inflammatory peptide Ac-SDKP is released from thymosin-β4 by renal meprin-α and prolyl oligopeptidase. (Kumar N, Nakagawa P, Janic B, Romero CA, Worou ME, Monu SR, Peterson EL, Shaw J, Valeriote F, Ongeri EM, Niyitegeka JM, Rhaleb NE, Carretero OA) Am J Physiol Renal Physiol 2016 May 15;310(10):F1026-34 42 Citations |
1 | Gammaherpesvirus targets peritoneal B-1 B cells for long-term latency. (Rekow MM, Darrah EJ, Mboko WP, Lange PT, Tarakanova VL) Virology 2016 May;492:140-4 25 Citations |
1 | Estrogen Receptor α Is Required for Maintaining Baseline Renin Expression. (Lu KT, Keen HL, Weatherford ET, Sequeira-Lopez ML, Gomez RA, Sigmund CD) Hypertension 2016 May;67(5):992-9 17 Citations |
5 | Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis. (Haribhai D, Ziegelbauer J, Jia S, Upchurch K, Yan K, Schmitt EG, Salzman NH, Simpson P, Hessner MJ, Chatila TA, Williams CB) J Immunol 2016 Apr 15;196(8):3305-17 37 Citations |
1 | Nociceptor Sensitization Depends on Age and Pain Chronicity(1,2,3). (Weyer AD, Zappia KJ, Garrison SR, O'Hara CL, Dodge AK, Stucky CL) eNeuro 2016;3(1) 40 Citations |
1 | Impact of Heparan Sulfate Binding on Transduction of Retina by Recombinant Adeno-Associated Virus Vectors. (Boye SL, Bennett A, Scalabrino ML, McCullough KT, Van Vliet K, Choudhury S, Ruan Q, Peterson J, Agbandje-McKenna M, Boye SE) J Virol 2016 Apr;90(8):4215-4231 55 Citations |
1 | Colon Cancer Tumorigenesis Initiated by the H1047R Mutant PI3K. (Yueh AE, Payne SN, Leystra AA, Van De Hey DR, Foley TM, Pasch CA, Clipson L, Matkowskyj KA, Deming DA) PLoS One 2016;11(2):e0148730 15 Citations |
1 | Estradiol-Mediated Spine Changes in the Dorsal Hippocampus and Medial Prefrontal Cortex of Ovariectomized Female Mice Depend on ERK and mTOR Activation in the Dorsal Hippocampus. (Tuscher JJ, Luine V, Frankfurt M, Frick KM) J Neurosci 2016 Feb 03;36(5):1483-9 111 Citations |
1 | Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson's Disease. (Ghosh A, Langley MR, Harischandra DS, Neal ML, Jin H, Anantharam V, Joseph J, Brenza T, Narasimhan B, Kanthasamy A, Kalyanaraman B, Kanthasamy AG) J Neuroimmune Pharmacol 2016 Jun;11(2):259-78 82 Citations |
3 | Intact Regulatory T-Cell Function but Defective Generation of IL-17A-Producing CD4+ T Cells in XIAP Deficiency. (Gurram B, Hammelev E, Syverson G, Haribhai D, Yan K, Simpson P, Salzman N, Verbsky JW) J Pediatr Gastroenterol Nutr 2016 Aug;63(2):218-25 |
2 | Extracellular Vesicles Activate a CD36-Dependent Signaling Pathway to Inhibit Microvascular Endothelial Cell Migration and Tube Formation. (Ramakrishnan DP, Hajj-Ali RA, Chen Y, Silverstein RL) Arterioscler Thromb Vasc Biol 2016 Mar;36(3):534-44 46 Citations |
1 | Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function. (Gray JM, Wilson CD, Lee TT, Pittman QJ, Deussing JM, Hillard CJ, McEwen BS, Schulkin J, Karatsoreos IN, Patel S, Hill MN) Psychoneuroendocrinology 2016 Apr;66:151-8 44 Citations |
2 | Kras Is Critical for B Cell Lymphopoiesis. (Chen Y, Zheng Y, You X, Yu M, Fu G, Su X, Zhou F, Zhu W, Wu Z, Zhang J, Wen R, Wang D) J Immunol 2016 Feb 15;196(4):1678-85 20 Citations |
1 | Fibrotic Aortic Valve Stenosis in Hypercholesterolemic/Hypertensive Mice. (Chu Y, Lund DD, Doshi H, Keen HL, Knudtson KL, Funk ND, Shao JQ, Cheng J, Hajj GP, Zimmerman KA, Davis MK, Brooks RM, Chapleau MW, Sigmund CD, Weiss RM, Heistad DD) Arterioscler Thromb Vasc Biol 2016 Mar;36(3):466-74 18 Citations |
1 | Chronic Co-Administration of Sepiapterin and L-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice. (Baumgardt SL, Paterson M, Leucker TM, Fang J, Zhang DX, Bosnjak ZJ, Warltier DC, Kersten JR, Ge ZD) Circ Heart Fail 2016 Jan;9(1):e002424 46 Citations |
2 | Type I Interferon Counteracts Antiviral Effects of Statins in the Context of Gammaherpesvirus Infection. (Lange PT, Darrah EJ, Vonderhaar EP, Mboko WP, Rekow MM, Patel SB, Sidjanin DJ, Tarakanova VL) J Virol 2016 Jan 06;90(7):3342-54 11 Citations |
2 | Tumor Suppressor Interferon-Regulatory Factor 1 Counteracts the Germinal Center Reaction Driven by a Cancer-Associated Gammaherpesvirus. (Mboko WP, Olteanu H, Ray A, Xin G, Darrah EJ, Kumar SN, Kulinski JM, Cui W, Dittel BN, Gauld SB, Tarakanova VL) J Virol 2015 Dec 30;90(6):2818-29 18 Citations |
1 | R-Ras Regulates Murine T Cell Migration and Intercellular Adhesion Molecule-1 Binding. (Yan X, Yan M, Guo Y, Singh G, Chen Y, Yu M, Wang D, Hillery CA, Chan AM) PLoS One 2015;10(12):e0145218 7 Citations |
1 | Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition Models. (Cheng J, Giguere PM, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Huang XP, Zhu H, McCorvy JD, Wetsel WC, Roth BL, Kozikowski AP) J Med Chem 2016 Jan 28;59(2):578-91 23 Citations |
1 | The Dose-Response Relationship of bacillus Calmette-Guérin and Urothelial Carcinoma Cell Biology. (Shah G, Zhang G, Chen F, Cao Y, Kalyanaraman B, See WA) J Urol 2016 Jun;195(6):1903-10 10 Citations |
2 | Genetic and pharmacological manipulation of glyoxalase 1 regulates voluntary ethanol consumption in mice. (McMurray KM, Sidhu PS, Cook JM, Arnold LA, Palmer AA) Addict Biol 2017 Mar;22(2):381-389 9 Citations |
2 | Vascular hepoxilin and trioxilins mediate vasorelaxation through TP receptor inhibition in mouse arteries. (Siangjong L, Goldman DH, Kriska T, Gauthier KM, Smyth EM, Puli N, Kumar G, Falck JR, Campbell WB) Acta Physiol (Oxf) 2017 Jan;219(1):188-201 18 Citations |
1 | Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition. (Ogasawara D, Deng H, Viader A, Baggelaar MP, Breman A, den Dulk H, van den Nieuwendijk AM, Soethoudt M, van der Wel T, Zhou J, Overkleeft HS, Sanchez-Alavez M, Mori S, Nguyen W, Conti B, Liu X, Chen Y, Liu QS, Cravatt BF, van der Stelt M) Proc Natl Acad Sci U S A 2016 Jan 05;113(1):26-33 103 Citations |
1 | Investigation of sex-specific effects of apolipoprotein E on severity of EAE and MS. (Schrewe L, Lill CM, Liu T, Salmen A, Gerdes LA, Guillot-Noel L, Akkad DA, Blaschke P, Graetz C, Hoffjan S, Kroner A, Demir S, Böhme A, Rieckmann P, ElAli A, Hagemann N, Hermann DM, Cournu-Rebeix I, Zipp F, Kümpfel T, Buttmann M, Zettl UK, Fontaine B, Bertram L, Gold R, Chan A) J Neuroinflammation 2015 Dec 16;12:234 8 Citations |
1 | Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. (Kiermaier E, Moussion C, Veldkamp CT, Gerardy-Schahn R, de Vries I, Williams LG, Chaffee GR, Phillips AJ, Freiberger F, Imre R, Taleski D, Payne RJ, Braun A, Förster R, Mechtler K, Mühlenhoff M, Volkman BF, Sixt M) Science 2016 Jan 08;351(6269):186-90 117 Citations |
1 | Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification. (Huk DJ, Austin BF, Horne TE, Hinton RB, Ray WC, Heistad DD, Lincoln J) Arterioscler Thromb Vasc Biol 2016 Feb;36(2):328-38 51 Citations |
1 | Endothelial PPAR-γ provides vascular protection from IL-1β-induced oxidative stress. (Mukohda M, Stump M, Ketsawatsomkron P, Hu C, Quelle FW, Sigmund CD) Am J Physiol Heart Circ Physiol 2016 Jan 01;310(1):H39-48 44 Citations |
1 | Exosome Adherence and Internalization by Hepatic Stellate Cells Triggers Sphingosine 1-Phosphate-dependent Migration. (Wang R, Ding Q, Yaqoob U, de Assuncao TM, Verma VK, Hirsova P, Cao S, Mukhopadhyay D, Huebert RC, Shah VH) J Biol Chem 2015 Dec 25;290(52):30684-96 177 Citations |
1 | Interference with PPARγ in endothelium accelerates angiotensin II-induced endothelial dysfunction. (Hu C, Lu KT, Mukohda M, Davis DR, Faraci FM, Sigmund CD) Physiol Genomics 2016 Feb;48(2):124-34 33 Citations |
2 | A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control. (Xin G, Schauder DM, Lainez B, Weinstein JS, Dai Z, Chen Y, Esplugues E, Wen R, Wang D, Parish IA, Zajac AJ, Craft J, Cui W) Cell Rep 2015 Nov 10;13(6):1118-1124 92 Citations |
2 | CaMKII Controls Whether Touch Is Painful. (Yu H, Pan B, Weyer A, Wu HE, Meng J, Fischer G, Vilceanu D, Light AR, Stucky C, Rice FL, Hudmon A, Hogan Q) J Neurosci 2015 Oct 21;35(42):14086-102 25 Citations |
1 | Erythropoietin Stimulates Tumor Growth via EphB4. (Pradeep S, Huang J, Mora EM, Nick AM, Cho MS, Wu SY, Noh K, Pecot CV, Rupaimoole R, Stein MA, Brock S, Wen Y, Xiong C, Gharpure K, Hansen JM, Nagaraja AS, Previs RA, Vivas-Mejia P, Han HD, Hu W, Mangala LS, Zand B, Stagg LJ, Ladbury JE, Ozpolat B, Alpay SN, Nishimura M, Stone RL, Matsuo K, Armaiz-Peña GN, Dalton HJ, Danes C, Goodman B, Rodriguez-Aguayo C, Kruger C, Schneider A, Haghpeykar S, Jaladurgam P, Hung MC, Coleman RL, Liu J, Li C, Urbauer D, Lopez-Berestein G, Jackson DB, Sood AK) Cancer Cell 2015 Nov 09;28(5):610-622 71 Citations |
2 | Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome. (Grose JH, Langston K, Wang X, Squires S, Mustafi SB, Hayes W, Neubert J, Fischer SK, Fasano M, Saunders GM, Dai Q, Christians E, Lewandowski ED, Ping P, Benjamin IJ) PLoS One 2015;10(10):e0133994 10 Citations |
3 | Comparison of platelet-derived and plasma factor VIII efficacy using a novel native whole blood thrombin generation assay. (Baumgartner CK, Zhang G, Kuether EL, Weiler H, Shi Q, Montgomery RR) J Thromb Haemost 2015 Dec;13(12):2210-9 12 Citations |
1 | Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact. (Ehlen JC, Jones KA, Pinckney L, Gray CL, Burette S, Weinberg RJ, Evans JA, Brager AJ, Zylka MJ, Paul KN, Philpot BD, DeBruyne JP) J Neurosci 2015 Oct 07;35(40):13587-98 60 Citations |
1 | Inhibitory effects of merocyanine 540-mediated photodynamic therapy on cellular immune functions: A role in the prophylaxis of graft-versus-host disease? (Traul DL, Sieber F) J Photochem Photobiol B 2015 Dec;153:153-63 13 Citations |
1 | CCR5-Dependent Activation of mTORC1 Regulates Translation of Inducible NO Synthase and COX-2 during Encephalomyocarditis Virus Infection. (Shaheen ZR, Naatz A, Corbett JA) J Immunol 2015 Nov 01;195(9):4406-14 10 Citations |
1 | Bilirubin prevents acute DSS-induced colitis by inhibiting leukocyte infiltration and suppressing upregulation of inducible nitric oxide synthase. (Zucker SD, Vogel ME, Kindel TL, Smith DL, Idelman G, Avissar U, Kakarlapudi G, Masnovi ME) Am J Physiol Gastrointest Liver Physiol 2015 Nov 15;309(10):G841-54 38 Citations |
1 | Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer. (Das S, Rachagani S, Sheinin Y, Smith LM, Gurumurthy CB, Roy HK, Batra SK) Oncogene 2016 May 19;35(20):2645-54 57 Citations |
2 | Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production. (Guo Y, Fan Y, Zhang J, Lomberk GA, Zhou Z, Sun L, Mathison AJ, Garcia-Barrio MT, Zhang J, Zeng L, Li L, Pennathur S, Willer CJ, Rader DJ, Urrutia R, Chen YE) J Clin Invest 2015 Oct 01;125(10):3819-30 62 Citations |
1 | Endocannabinoid regulation of amyloid-induced neuroinflammation. (Vázquez C, Tolón RM, Grande MT, Caraza M, Moreno M, Koester EC, Villaescusa B, Ruiz-Valdepeñas L, Fernández-Sánchez FJ, Cravatt BF, Hillard CJ, Romero J) Neurobiol Aging 2015 Nov;36(11):3008-3019 28 Citations |
1 | Systemic Vascular Transduction by Capsid Mutant Adeno-Associated Virus After Intravenous Injection. (Lipinski DM, Reid CA, Boye SL, Peterson JJ, Qi X, Boye SE, Boulton ME, Hauswirth WW) Hum Gene Ther 2015 Nov;26(11):767-76 10 Citations |
1 | Gut Microbial Dysbiosis Due to Helicobacter Drives an Increase in Marginal Zone B Cells in the Absence of IL-10 Signaling in Macrophages. (Ray A, Basu S, Gharaibeh RZ, Cook LC, Kumar R, Lefkowitz EJ, Walker CR, Morrow CD, Franklin CL, Geiger TL, Salzman NH, Fodor A, Dittel BN) J Immunol 2015 Oct 01;195(7):3071-85 21 Citations |
1 | NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1. (Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG) J Exp Med 2015 Sep 21;212(10):1725-38 92 Citations |
1 | Regulating anxiety with extrasynaptic inhibition. (Botta P, Demmou L, Kasugai Y, Markovic M, Xu C, Fadok JP, Lu T, Poe MM, Xu L, Cook JM, Rudolph U, Sah P, Ferraguti F, Lüthi A) Nat Neurosci 2015 Oct;18(10):1493-500 132 Citations |
1 | Intravitreal delivery of a novel AAV vector targets ON bipolar cells and restores visual function in a mouse model of complete congenital stationary night blindness. (Scalabrino ML, Boye SL, Fransen KM, Noel JM, Dyka FM, Min SH, Ruan Q, De Leeuw CN, Simpson EM, Gregg RG, McCall MA, Peachey NS, Boye SE) Hum Mol Genet 2015 Nov 01;24(21):6229-39 58 Citations |
1 | Glycine transporter 1 is a target for the treatment of epilepsy. (Shen HY, van Vliet EA, Bright KA, Hanthorn M, Lytle NK, Gorter J, Aronica E, Boison D) Neuropharmacology 2015 Dec;99:554-65 36 Citations |
4 | Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase. (Zhi H, Dai J, Liu J, Zhu J, Newman DK, Gao C, Newman PJ) PLoS One 2015;10(8):e0135738 28 Citations |
2 | Endogenous microRNAs in human microvascular endothelial cells regulate mRNAs encoded by hypertension-related genes. (Kriegel AJ, Baker MA, Liu Y, Liu P, Cowley AW Jr, Liang M) Hypertension 2015 Oct;66(4):793-9 87 Citations |
1 | MicroRNA-21 Mediates Isoflurane-induced Cardioprotection against Ischemia-Reperfusion Injury via Akt/Nitric Oxide Synthase/Mitochondrial Permeability Transition Pore Pathway. (Qiao S, Olson JM, Paterson M, Yan Y, Zaja I, Liu Y, Riess ML, Kersten JR, Liang M, Warltier DC, Bosnjak ZJ, Ge ZD) Anesthesiology 2015 Oct;123(4):786-798 69 Citations |
1 | Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis. (Lochhead RB, Zachary JF, Dalla Rosa L, Ma Y, Weis JH, O'Connell RM, Weis JJ) PLoS One 2015;10(8):e0135142 21 Citations |
3 | Phenotypic Characterization of Mice Carrying Homozygous Deletion of KLF11, a Gene in Which Mutations Cause Human Neonatal and MODY VII Diabetes. (Mathison A, Escande C, Calvo E, Seo S, White T, Salmonson A, Faubion WA Jr, Buttar N, Iovanna J, Lomberk G, Chini EN, Urrutia R) Endocrinology 2015 Oct;156(10):3581-95 9 Citations |
1 | Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia. (Kwon HY, Bajaj J, Ito T, Blevins A, Konuma T, Weeks J, Lytle NK, Koechlein CS, Rizzieri D, Chuah C, Oehler VG, Sasik R, Hardiman G, Reya T) Cell Stem Cell 2015 Aug 06;17(2):152-164 55 Citations |
1 | Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. (Liu H, Tang X, Srivastava A, Pécot T, Daniel P, Hemmelgarn B, Reyes S, Fackler N, Bajwa A, Kladney R, Koivisto C, Chen Z, Wang Q, Huang K, Machiraju R, Sáenz-Robles MT, Cantalupo P, Pipas JM, Leone G) Nat Cell Biol 2015 Aug;17(8):1036-48 56 Citations |
1 | A Candida albicans Strain Expressing Mammalian Interleukin-17A Results in Early Control of Fungal Growth during Disseminated Infection. (Huppler AR, Whibley N, Woolford CA, Childs EE, He J, Biswas PS, McGeachy MJ, Mitchell AP, Gaffen SL) Infect Immun 2015 Sep;83(9):3684-92 4 Citations |
1 | MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice. (Wu Y, Heinrichs J, Bastian D, Fu J, Nguyen H, Schutt S, Liu Y, Jin J, Liu C, Li QJ, Xia C, Yu XZ) Blood 2015 Sep 10;126(11):1314-23 52 Citations |
1 | Shell neurons of the master circadian clock coordinate the phase of tissue clocks throughout the brain and body. (Evans JA, Suen TC, Callif BL, Mitchell AS, Castanon-Cervantes O, Baker KM, Kloehn I, Baba K, Teubner BJ, Ehlen JC, Paul KN, Bartness TJ, Tosini G, Leise T, Davidson AJ) BMC Biol 2015 Jun 23;13:43 42 Citations |
1 | Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins. (Starks RD, Beyer AM, Guo DF, Boland L, Zhang Q, Sheffield VC, Rahmouni K) PLoS Genet 2015 Jun;11(6):e1005311 50 Citations |
2 | Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway. (Mammoto T, Chen Z, Jiang A, Jiang E, Ingber DE, Mammoto A) Am J Respir Cell Mol Biol 2016 Jan;54(1):103-13 22 Citations |
1 | Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function. (Prasad AM, Morgan DA, Nuno DW, Ketsawatsomkron P, Bair TB, Venema AN, Dibbern ME, Kutschke WJ, Weiss RM, Lamping KG, Chapleau MW, Sigmund CD, Rahmouni K, Grumbach IM) J Am Heart Assoc 2015 Jun 15;4(6):e001949 35 Citations |
1 | HTR7 Mediates Serotonergic Acute and Chronic Itch. (Morita T, McClain SP, Batia LM, Pellegrino M, Wilson SR, Kienzler MA, Lyman K, Olsen AS, Wong JF, Stucky CL, Brem RB, Bautista DM) Neuron 2015 Jul 01;87(1):124-38 137 Citations |
1 | HY-Specific Induced Regulatory T Cells Display High Specificity and Efficacy in the Prevention of Acute Graft-versus-Host Disease. (Li J, Heinrichs J, Haarberg K, Semple K, Veerapathran A, Liu C, Anasetti C, Yu XZ) J Immunol 2015 Jul 15;195(2):717-25 21 Citations |
1 | Associations of ApoAI and ApoB-containing lipoproteins with AngII-induced abdominal aortic aneurysms in mice. (Liu J, Lu H, Howatt DA, Balakrishnan A, Moorleghen JJ, Sorci-Thomas M, Cassis LA, Daugherty A) Arterioscler Thromb Vasc Biol 2015 Aug;35(8):1826-34 33 Citations |
1 | An endocannabinoid system is present in the mouse olfactory epithelium but does not modulate olfaction. (Hutch CR, Hillard CJ, Jia C, Hegg CC) Neuroscience 2015 Aug 06;300:539-53 14 Citations |
2 | ATM facilitates mouse gammaherpesvirus reactivation from myeloid cells during chronic infection. (Kulinski JM, Darrah EJ, Broniowska KA, Mboko WP, Mounce BC, Malherbe LP, Corbett JA, Gauld SB, Tarakanova VL) Virology 2015 Sep;483:264-74 10 Citations |
1 | Cold shock induces apoptosis of dorsal root ganglion neurons plated on infrared windows. (Aboualizadeh E, Mattson EC, O'Hara CL, Smith AK, Stucky CL, Hirschmugl CJ) Analyst 2015 Jun 21;140(12):4046-56 2 Citations |
1 | Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice. (Ghosh S, Kinsey SG, Liu QS, Hruba L, McMahon LR, Grim TW, Merritt CR, Wise LE, Abdullah RA, Selley DE, Sim-Selley LJ, Cravatt BF, Lichtman AH) J Pharmacol Exp Ther 2015 Aug;354(2):111-20 33 Citations |
1 | NADPH Oxidase-Derived Peroxynitrite Drives Inflammation in Mice and Human Nonalcoholic Steatohepatitis via TLR4-Lipid Raft Recruitment. (Das S, Alhasson F, Dattaroy D, Pourhoseini S, Seth RK, Nagarkatti M, Nagarkatti PS, Michelotti GA, Diehl AM, Kalyanaraman B, Chatterjee S) Am J Pathol 2015 Jul;185(7):1944-57 36 Citations |
1 | Targeting epidermal fatty acid binding protein for treatment of experimental autoimmune encephalomyelitis. (Rao E, Singh P, Li Y, Zhang Y, Chi YI, Suttles J, Li B) BMC Immunol 2015 May 12;16:28 25 Citations |
3 | p38γ MAPK is required for inflammation-associated colon tumorigenesis. (Yin N, Qi X, Tsai S, Lu Y, Basir Z, Oshima K, Thomas JP, Myers CR, Stoner G, Chen G) Oncogene 2016 Feb 25;35(8):1039-48 31 Citations |
2 | The important role of von Willebrand factor in platelet-derived FVIII gene therapy for murine hemophilia A in the presence of inhibitory antibodies. (Shi Q, Schroeder JA, Kuether EL, Montgomery RR) J Thromb Haemost 2015 Jul;13(7):1301-9 17 Citations |
1 | A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior. (Vardy E, Robinson JE, Li C, Olsen RHJ, DiBerto JF, Giguere PM, Sassano FM, Huang XP, Zhu H, Urban DJ, White KL, Rittiner JE, Crowley NA, Pleil KE, Mazzone CM, Mosier PD, Song J, Kash TL, Malanga CJ, Krashes MJ, Roth BL) Neuron 2015 May 20;86(4):936-946 271 Citations |
1 | Hemodynamic Characterization of a Mouse Model for Investigating the Cellular and Molecular Mechanisms of Neotissue Formation in Tissue-Engineered Heart Valves. (James IA, Yi T, Tara S, Best CA, Stuber AJ, Shah KV, Austin BF, Sugiura T, Lee YU, Lincoln J, Trask AJ, Shinoka T, Breuer CK) Tissue Eng Part C Methods 2015 Sep;21(9):987-94 13 Citations |
2 | Astrocytes influence the severity of spinal muscular atrophy. (Rindt H, Feng Z, Mazzasette C, Glascock JJ, Valdivia D, Pyles N, Crawford TO, Swoboda KJ, Patitucci TN, Ebert AD, Sumner CJ, Ko CP, Lorson CL) Hum Mol Genet 2015 Jul 15;24(14):4094-102 89 Citations |
1 | Phosphoinositide and Erk signaling pathways mediate activity-driven rodent olfactory sensory neuronal survival and stress mitigation. (Kim SY, Mammen A, Yoo SJ, Cho B, Kim EK, Park JI, Moon C, Ronnett GV) J Neurochem 2015 Aug;134(3):486-98 13 Citations |
2 | Brain endoplasmic reticulum stress mechanistically distinguishes the saline-intake and hypertensive response to deoxycorticosterone acetate-salt. (Jo F, Jo H, Hilzendeger AM, Thompson AP, Cassell MD, Rutkowski DT, Davisson RL, Grobe JL, Sigmund CD) Hypertension 2015 Jun;65(6):1341-8 16 Citations |
1 | CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa. (Lipinski DM, Barnard AR, Singh MS, Martin C, Lee EJ, Davies WIL, MacLaren RE) Mol Ther 2015 Aug;23(8):1308-1319 65 Citations |
1 | Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1β Production upon Extrinsic Stimulation in Culture. (Cieniewicz B, Dong Q, Li G, Forrest JC, Mounce BC, Tarakanova VL, van der Velden A, Krug LT) J Virol 2015 Jul;89(13):6562-74 19 Citations |
6 | Acrolein impairs the cholesterol transport functions of high density lipoproteins. (Chadwick AC, Holme RL, Chen Y, Thomas MJ, Sorci-Thomas MG, Silverstein RL, Pritchard KA Jr, Sahoo D) PLoS One 2015;10(4):e0123138 33 Citations |
1 | Essential Role of Interleukin-12/23p40 in the Development of Graft-versus-Host Disease in Mice. (Wu Y, Bastian D, Schutt S, Nguyen H, Fu J, Heinrichs J, Xia C, Yu XZ) Biol Blood Marrow Transplant 2015 Jul;21(7):1195-204 22 Citations |
2 | FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets. (Begonja AJ, Pluthero FG, Suphamungmee W, Giannini S, Christensen H, Leung R, Lo RW, Nakamura F, Lehman W, Plomann M, Hoffmeister KM, Kahr WH, Hartwig JH, Falet H) Blood 2015 Jul 02;126(1):80-8 49 Citations |
1 | cCMP and cUMP occur in vivo. (Bähre H, Hartwig C, Munder A, Wolter S, Stelzer T, Schirmer B, Beckert U, Frank DW, Tümmler B, Kaever V, Seifert R) Biochem Biophys Res Commun 2015 May 15;460(4):909-14 29 Citations |
1 | DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia. (Chen CW, Koche RP, Sinha AU, Deshpande AJ, Zhu N, Eng R, Doench JG, Xu H, Chu SH, Qi J, Wang X, Delaney C, Bernt KM, Root DE, Hahn WC, Bradner JE, Armstrong SA) Nat Med 2015 Apr;21(4):335-43 175 Citations |
1 | BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons. (Zhong P, Liu Y, Hu Y, Wang T, Zhao YP, Liu QS) J Neurosci 2015 Mar 11;35(10):4469-81 33 Citations |
2 | EPCR-dependent PAR2 activation by the blood coagulation initiation complex regulates LPS-triggered interferon responses in mice. (Liang HP, Kerschen EJ, Hernandez I, Basu S, Zogg M, Botros F, Jia S, Hessner MJ, Griffin JH, Ruf W, Weiler H) Blood 2015 Apr 30;125(18):2845-54 62 Citations |
1 | Expression of iron homeostasis proteins in the spinal cord in experimental autoimmune encephalomyelitis and their implications for iron accumulation. (Zarruk JG, Berard JL, Passos dos Santos R, Kroner A, Lee J, Arosio P, David S) Neurobiol Dis 2015 Sep;81:93-107 60 Citations |
1 | Redox signaling and splicing dependent change in myosin phosphatase underlie early versus late changes in NO vasodilator reserve in a mouse LPS model of sepsis. (Reho JJ, Zheng X, Asico LD, Fisher SA) Am J Physiol Heart Circ Physiol 2015 May 01;308(9):H1039-50 19 Citations |
1 | Alcohol inhibits osteopontin-dependent transforming growth factor-β1 expression in human mesenchymal stem cells. (Driver J, Weber CE, Callaci JJ, Kothari AN, Zapf MA, Roper PM, Borys D, Franzen CA, Gupta GN, Wai PY, Zhang J, Denning MF, Kuo PC, Mi Z) J Biol Chem 2015 Apr 17;290(16):9959-73 27 Citations |
1 | Overexpression of Sox11 promotes corticospinal tract regeneration after spinal injury while interfering with functional recovery. (Wang Z, Reynolds A, Kirry A, Nienhaus C, Blackmore MG) J Neurosci 2015 Feb 18;35(7):3139-45 113 Citations |
1 | Survival advantage of heterozygous factor V Leiden carriers in murine sepsis. (Kerschen E, Hernandez I, Zogg M, Maas M, Weiler H) J Thromb Haemost 2015 Jun;13(6):1073-80 9 Citations |
1 | Endothelial PPAR-γ protects against vascular thrombosis by downregulating P-selectin expression. (Jin H, Gebska MA, Blokhin IO, Wilson KM, Ketsawatsomkron P, Chauhan AK, Keen HL, Sigmund CD, Lentz SR) Arterioscler Thromb Vasc Biol 2015 Apr;35(4):838-44 33 Citations |
1 | Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. (Illendula A, Pulikkan JA, Zong H, Grembecka J, Xue L, Sen S, Zhou Y, Boulton A, Kuntimaddi A, Gao Y, Rajewski RA, Guzman ML, Castilla LH, Bushweller JH) Science 2015 Feb 13;347(6223):779-84 94 Citations |
1 | AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. (Lehto SG, Weyer AD, Zhang M, Youngblood BD, Wang J, Wang W, Kerstein PC, Davis C, Wild KD, Stucky CL, Gavva NR) Naunyn Schmiedebergs Arch Pharmacol 2015 Apr;388(4):465-76 20 Citations |
1 | Behavioral effects of the benzodiazepine-positive allosteric modulator SH-053-2'F-S-CH₃ in an immune-mediated neurodevelopmental disruption model. (Richetto J, Labouesse MA, Poe MM, Cook JM, Grace AA, Riva MA, Meyer U) Int J Neuropsychopharmacol 2015 Jan 30;18(4) 22 Citations |
1 | Toll-like receptor 4 mediates the regenerative effects of bone grafts for calvarial bone repair. (Wang D, Gilbert JR, Shaw MA, Shakir S, Losee JE, Billiar TR, Cooper GM) Tissue Eng Part A 2015 Apr;21(7-8):1299-308 11 Citations |
1 | PTEN is a negative regulator of NK cell cytolytic function. (Briercheck EL, Trotta R, Chen L, Hartlage AS, Cole JP, Cole TD, Mao C, Banerjee PP, Hsu HT, Mace EM, Ciarlariello D, Mundy-Bosse BL, Garcia-Cao I, Scoville SD, Yu L, Pilarski R, Carson WE 3rd, Leone G, Pandolfi PP, Yu J, Orange JS, Caligiuri MA) J Immunol 2015 Feb 15;194(4):1832-40 34 Citations |
2 | Critical role of CD4 T cells in PF4/heparin antibody production in mice. (Zheng Y, Yu M, Padmanabhan A, Aster RH, Yuan L, Wen R, Wang D) Blood 2015 Mar 12;125(11):1826-9 24 Citations |
1 | Identification and specification of the mouse skeletal stem cell. (Chan CK, Seo EY, Chen JY, Lo D, McArdle A, Sinha R, Tevlin R, Seita J, Vincent-Tompkins J, Wearda T, Lu WJ, Senarath-Yapa K, Chung MT, Marecic O, Tran M, Yan KS, Upton R, Walmsley GG, Lee AS, Sahoo D, Kuo CJ, Weissman IL, Longaker MT) Cell 2015 Jan 15;160(1-2):285-98 506 Citations |
1 | Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation. (Sohni A, Bartoccetti M, Khoueiry R, Spans L, Vande Velde J, De Troyer L, Pulakanti K, Claessens F, Rao S, Koh KP) Mol Cell Biol 2015 Mar;35(6):1026-42 41 Citations |
1 | Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation. (Dinarvand P, Hassanian SM, Weiler H, Rezaie AR) Blood 2015 Feb 19;125(8):1339-48 25 Citations |
1 | Lipopolysaccharide (LPS)-mediated angiopoietin-2-dependent autocrine angiogenesis is regulated by NADPH oxidase 2 (Nox2) in human pulmonary microvascular endothelial cells. (Menden H, Welak S, Cossette S, Ramchandran R, Sampath V) J Biol Chem 2015 Feb 27;290(9):5449-61 61 Citations |
3 | Structure-function analysis of CCL28 in the development of post-viral asthma. (Thomas MA, Buelow BJ, Nevins AM, Jones SE, Peterson FC, Gundry RL, Grayson MH, Volkman BF) J Biol Chem 2015 Feb 13;290(7):4528-36 18 Citations |
1 | A peripheral endocannabinoid mechanism contributes to glucocorticoid-mediated metabolic syndrome. (Bowles NP, Karatsoreos IN, Li X, Vemuri VK, Wood JA, Li Z, Tamashiro KL, Schwartz GJ, Makriyannis AM, Kunos G, Hillard CJ, McEwen BS, Hill MN) Proc Natl Acad Sci U S A 2015 Jan 06;112(1):285-90 82 Citations |
1 | Evidence revealing deregulation of the KLF11-MAO A pathway in association with chronic stress and depressive disorders. (Harris S, Johnson S, Duncan JW, Udemgba C, Meyer JH, Albert PR, Lomberk G, Urrutia R, Ou XM, Stockmeier CA, Wang JM) Neuropsychopharmacology 2015 May;40(6):1373-82 30 Citations |
1 | Prenatal stress induces spatial memory deficits and epigenetic changes in the hippocampus indicative of heterochromatin formation and reduced gene expression. (Benoit JD, Rakic P, Frick KM) Behav Brain Res 2015 Mar 15;281:1-8 78 Citations |
1 | Dietary supplementation with docosahexanoic acid (DHA) increases red blood cell membrane flexibility in mice with sickle cell disease. (Wandersee NJ, Maciaszek JL, Giger KM, Hanson MS, Zheng S, Guo Y, Mickelson B, Hillery CA, Lykotrafitis G, Low PS, Hogg N) Blood Cells Mol Dis 2015 Feb;54(2):183-8 21 Citations |
1 | The mTOR and canonical Wnt signaling pathways mediate the mnemonic effects of progesterone in the dorsal hippocampus. (Fortress AM, Heisler JD, Frick KM) Hippocampus 2015 May;25(5):616-29 24 Citations |
2 | Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice. (Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ) BMC Genet 2014 Dec 05;15:135 17 Citations |
1 | Krüppel-like factor KLF10 regulates transforming growth factor receptor II expression and TGF-β signaling in CD8+ T lymphocytes. (Papadakis KA, Krempski J, Reiter J, Svingen P, Xiong Y, Sarmento OF, Huseby A, Johnson AJ, Lomberk GA, Urrutia RA, Faubion WA) Am J Physiol Cell Physiol 2015 Mar 01;308(5):C362-71 21 Citations |
2 | Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice. (Bender M, Giannini S, Grozovsky R, Jönsson T, Christensen H, Pluthero FG, Ko A, Mullally A, Kahr WH, Hoffmeister KM, Falet H) Blood 2015 Feb 05;125(6):1014-24 42 Citations |
1 | Enkephalin is essential for the molecular and behavioral expression of cocaine sensitization. (Mongi-Bragato B, Zamponi E, García-Keller C, Assis MA, Virgolini MB, Mascó DH, Zimmer A, Cancela LM) Addict Biol 2016 Mar;21(2):326-38 15 Citations |
1 | TRA2β controls Mypt1 exon 24 splicing in the developmental maturation of mouse mesenteric artery smooth muscle. (Zheng X, Reho JJ, Wirth B, Fisher SA) Am J Physiol Cell Physiol 2015 Feb 15;308(4):C289-96 15 Citations |
1 | Endothelial TWIST1 promotes pathological ocular angiogenesis. (Li J, Liu CH, Sun Y, Gong Y, Fu Z, Evans LP, Tian KT, Juan AM, Hurst CG, Mammoto A, Chen J) Invest Ophthalmol Vis Sci 2014 Nov 20;55(12):8267-77 37 Citations |
1 | Protein tyrosine phosphatase-σ regulates hematopoietic stem cell-repopulating capacity. (Quarmyne M, Doan PL, Himburg HA, Yan X, Nakamura M, Zhao L, Chao NJ, Chute JP) J Clin Invest 2015 Jan;125(1):177-82 21 Citations |
1 | T-bet is critical for the development of acute graft-versus-host disease through controlling T cell differentiation and function. (Fu J, Wang D, Yu Y, Heinrichs J, Wu Y, Schutt S, Kaosaard K, Liu C, Haarberg K, Bastian D, McDonald DG, Anasetti C, Yu XZ) J Immunol 2015 Jan 01;194(1):388-97 33 Citations |
1 | Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/B×N serum transfer arthritis through intrinsic control of type I IFN production. (Ma Y, Bramwell KK, Lochhead RB, Paquette JK, Zachary JF, Weis JH, Teuscher C, Weis JJ) J Immunol 2014 Dec 15;193(12):6050-60 15 Citations |
1 | Attenuation of cystitis and pain sensation in mice lacking fatty acid amide hydrolase. (Wang ZY, Wang P, Hillard CJ, Bjorling DE) J Mol Neurosci 2015 Apr;55(4):968-76 13 Citations |
1 | Type 1 equilibrative nucleoside transporter regulates astrocyte-specific glial fibrillary acidic protein expression in the striatum. (Hinton DJ, Lee MR, Jang JS, Choi DS) Brain Behav 2014;4(6):903-14 13 Citations |
1 | Overexpression of activated protein C hampers bacterial dissemination during pneumococcal pneumonia. (de Boer JD, Kager LM, Roelofs JJ, Meijers JC, de Boer OJ, Weiler H, Isermann B, van 't Veer C, van der Poll T) BMC Infect Dis 2014 Nov 04;14:559 9 Citations |
1 | IgG2 antibodies against a clinical grade Plasmodium falciparum CSP vaccine antigen associate with protection against transgenic sporozoite challenge in mice. (Schwenk R, DeBot M, Porter M, Nikki J, Rein L, Spaccapelo R, Crisanti A, Wightman PD, Ockenhouse CF, Dutta S) PLoS One 2014;9(10):e111020 55 Citations |
3 | Sickle cell disease increases high mobility group box 1: a novel mechanism of inflammation. (Xu H, Wandersee NJ, Guo Y, Jones DW, Holzhauer SL, Hanson MS, Machogu E, Brousseau DC, Hogg N, Densmore JC, Kaul S, Hillery CA, Pritchard KA Jr) Blood 2014 Dec 18;124(26):3978-81 44 Citations |
1 | Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension. (González GE, Rhaleb NE, D'Ambrosio MA, Nakagawa P, Liu Y, Leung P, Dai X, Yang XP, Peterson EL, Carretero OA) J Hypertens 2015 Jan;33(1):144-52 83 Citations |
1 | A mitochondrial-targeted coenzyme q analog prevents weight gain and ameliorates hepatic dysfunction in high-fat-fed mice. (Fink BD, Herlein JA, Guo DF, Kulkarni C, Weidemann BJ, Yu L, Grobe JL, Rahmouni K, Kerns RJ, Sivitz WI) J Pharmacol Exp Ther 2014 Dec;351(3):699-708 35 Citations |
1 | Thymidine phosphorylase participates in platelet signaling and promotes thrombosis. (Li W, Gigante A, Perez-Perez MJ, Yue H, Hirano M, McIntyre TM, Silverstein RL) Circ Res 2014 Dec 05;115(12):997-1006 32 Citations |
1 | Chemical structure and morphology of dorsal root ganglion neurons from naive and inflamed mice. (Barabas ME, Mattson EC, Aboualizadeh E, Hirschmugl CJ, Stucky CL) J Biol Chem 2014 Dec 05;289(49):34241-9 21 Citations |
1 | Ibrutinib treatment ameliorates murine chronic graft-versus-host disease. (Dubovsky JA, Flynn R, Du J, Harrington BK, Zhong Y, Kaffenberger B, Yang C, Towns WH, Lehman A, Johnson AJ, Muthusamy N, Devine SM, Jaglowski S, Serody JS, Murphy WJ, Munn DH, Luznik L, Hill GR, Wong HK, MacDonald KK, Maillard I, Koreth J, Elias L, Cutler C, Soiffer RJ, Antin JH, Ritz J, Panoskaltsis-Mortari A, Byrd JC, Blazar BR) J Clin Invest 2014 Nov;124(11):4867-76 146 Citations |
1 | Actin dynamics is rapidly regulated by the PTEN and PIP2 signaling pathways leading to myocyte hypertrophy. (Li J, Tanhehco EJ, Russell B) Am J Physiol Heart Circ Physiol 2014 Dec 01;307(11):H1618-25 27 Citations |
1 | Heat shock protein-mediated protection against Cisplatin-induced hair cell death. (Baker TG, Roy S, Brandon CS, Kramarenko IK, Francis SP, Taleb M, Marshall KM, Schwendener R, Lee FS, Cunningham LL) J Assoc Res Otolaryngol 2015 Feb;16(1):67-80 29 Citations |
1 | MACE: model based analysis of ChIP-exo. (Wang L, Chen J, Wang C, Uusküla-Reimand L, Chen K, Medina-Rivera A, Young EJ, Zimmermann MT, Yan H, Sun Z, Zhang Y, Wu ST, Huang H, Wilson MD, Kocher JP, Li W) Nucleic Acids Res 2014 Nov 10;42(20):e156 63 Citations |
2 | Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner. (Milanovich S, Peterson J, Allred J, Stelloh C, Rajasekaran K, Fisher J, Duncan SA, Malarkannan S, Rao S) Exp Hematol 2015 Jan;43(1):53-64.e1-8 15 Citations |
3 | Identification of a novel gene for diabetic traits in rats, mice, and humans. (Tsaih SW, Holl K, Jia S, Kaldunski M, Tschannen M, He H, Andrae JW, Li SH, Stoddard A, Wiederhold A, Parrington J, Ruas da Silva M, Galione A, Meigs J, Meta-Analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) Investigators, Hoffmann RG, Simpson P, Jacob H, Hessner M, Solberg Woods LC) Genetics 2014 Sep;198(1):17-29 36 Citations |
1 | CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth. (Mathsyaraja H, Thies K, Taffany DA, Deighan C, Liu T, Yu L, Fernandez SA, Shapiro C, Otero J, Timmers C, Lustberg MB, Chalmers J, Leone G, Ostrowski MC) Oncogene 2015 Jul;34(28):3651-61 53 Citations |
1 | Hyper-inflammation and skin destruction mediated by rosiglitazone activation of macrophages in IL-6 deficiency. (Das LM, Rosenjack J, Au L, Galle PS, Hansen MB, Cathcart MK, McCormick TS, Cooper KD, Silverstein RL, Lu KQ) J Invest Dermatol 2015 Feb;135(2):389-399 13 Citations |
1 | Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36 and inhibits pro-atherothombotic cellular functions. (Srikanthan S, Li W, Silverstein RL, McIntyre TM) J Thromb Haemost 2014 Nov;12(11):1906-17 91 Citations |
1 | In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection. (Myint M, Limberis MP, Bell P, Somanathan S, Haczku A, Wilson JM, Diamond SL) Hum Gene Ther 2014 Nov;25(11):966-76 10 Citations |
1 | Chronic passive venous congestion drives hepatic fibrogenesis via sinusoidal thrombosis and mechanical forces. (Simonetto DA, Yang HY, Yin M, de Assuncao TM, Kwon JH, Hilscher M, Pan S, Yang L, Bi Y, Beyder A, Cao S, Simari RD, Ehman R, Kamath PS, Shah VH) Hepatology 2015 Feb;61(2):648-59 132 Citations |
1 | TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord. (Kroner A, Greenhalgh AD, Zarruk JG, Passos Dos Santos R, Gaestel M, David S) Neuron 2014 Sep 03;83(5):1098-116 457 Citations |
1 | Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity. (Zhang Z, Wang W, Zhong P, Liu SJ, Long JZ, Zhao L, Gao HQ, Cravatt BF, Liu QS) Hippocampus 2015 Jan;25(1):16-26 77 Citations |
1 | Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help. (Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ) PLoS One 2014;9(8):e102709 26 Citations |
2 | Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension. (Carrillo-Sepulveda MA, Keen HL, Davis DR, Grobe JL, Sigmund CD) PLoS One 2014;9(8):e103786 11 Citations |
1 | Collecting duct-specific knockout of renin attenuates angiotensin II-induced hypertension. (Ramkumar N, Stuart D, Rees S, Hoek AV, Sigmund CD, Kohan DE) Am J Physiol Renal Physiol 2014 Oct 15;307(8):F931-8 49 Citations |
1 | Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy. (Marshall KM, He S, Zhong Z, Atkinson C, Tomlinson S) J Exp Med 2014 Aug 25;211(9):1793-805 58 Citations |
1 | PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation. (Meares GP, Liu Y, Rajbhandari R, Qin H, Nozell SE, Mobley JA, Corbett JA, Benveniste EN) Mol Cell Biol 2014 Oct;34(20):3911-25 165 Citations |
1 | The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation. (Kumar S, Xu J, Kumar RS, Lakshmikanthan S, Kapur R, Kofron M, Chrzanowska-Wodnicka M, Filippi MD) J Exp Med 2014 Aug 25;211(9):1741-58 51 Citations |
1 | Phase-aligned multiple spin-echo averaging: a simple way to improve signal-to-noise ratio of in vivo mouse spinal cord diffusion tensor image. (Tu TW, Budde MD, Xie M, Chen YJ, Wang Q, Quirk JD, Song SK) Magn Reson Imaging 2014 Dec;32(10):1335-43 8 Citations |
2 | Non-myeloablative conditioning with busulfan before hematopoietic stem cell transplantation leads to phenotypic correction of murine Bernard-Soulier syndrome. (Kanaji S, Fahs SA, Ware J, Montgomery RR, Shi Q) J Thromb Haemost 2014 Oct;12(10):1726-32 6 Citations |
1 | Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. (Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH) Hum Mol Genet 2014 Dec 15;23(24):6528-41 71 Citations |
2 | Hematogenous metastasis of ovarian cancer: rethinking mode of spread. (Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, Zand B, Dalton HJ, Arumugam T, Lee HJ, Han HD, Cho MS, Rupaimoole R, Mangala LS, Sehgal V, Oh SC, Liu J, Lee JS, Coleman RL, Ram P, Lopez-Berestein G, Fidler IJ, Sood AK) Cancer Cell 2014 Jul 14;26(1):77-91 238 Citations |
1 | Effect of high-intensity exercise on aged mouse brain mitochondria, neurogenesis, and inflammation. (E L, Burns JM, Swerdlow RH) Neurobiol Aging 2014 Nov;35(11):2574-2583 72 Citations |
1 | Vasopressin in preeclampsia: a novel very early human pregnancy biomarker and clinically relevant mouse model. (Santillan MK, Santillan DA, Scroggins SM, Min JY, Sandgren JA, Pearson NA, Leslie KK, Hunter SK, Zamba GK, Gibson-Corley KN, Grobe JL) Hypertension 2014 Oct;64(4):852-9 107 Citations |
1 | Monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model. (Fernández-Suárez D, Celorrio M, Riezu-Boj JI, Ugarte A, Pacheco R, González H, Oyarzabal J, Hillard CJ, Franco R, Aymerich MS) Neurobiol Aging 2014 Nov;35(11):2603-2616 72 Citations |
1 | Direct interaction of kindlin-3 with integrin αIIbβ3 in platelets is required for supporting arterial thrombosis in mice. (Xu Z, Chen X, Zhi H, Gao J, Bialkowska K, Byzova TV, Pluskota E, White GC 2nd, Liu J, Plow EF, Ma YQ) Arterioscler Thromb Vasc Biol 2014 Sep;34(9):1961-7 36 Citations |
1 | Regulation of high-density lipoprotein on hematopoietic stem/progenitor cells in atherosclerosis requires scavenger receptor type BI expression. (Gao M, Zhao D, Schouteden S, Sorci-Thomas MG, Van Veldhoven PP, Eggermont K, Liu G, Verfaillie CM, Feng Y) Arterioscler Thromb Vasc Biol 2014 Sep;34(9):1900-9 54 Citations |
2 | Activation of the renin-angiotensin system, specifically in the subfornical organ is sufficient to induce fluid intake. (Coble JP, Cassell MD, Davis DR, Grobe JL, Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2014 Aug 15;307(4):R376-86 20 Citations |
1 | MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi. (Lochhead RB, Ma Y, Zachary JF, Baltimore D, Zhao JL, Weis JH, O'Connell RM, Weis JJ) PLoS Pathog 2014 Jun;10(6):e1004212 36 Citations |
1 | Cold hypersensitivity increases with age in mice with sickle cell disease. (Zappia KJ, Garrison SR, Hillery CA, Stucky CL) Pain 2014 Dec;155(12):2476-2485 50 Citations |
1 | An essential role of interleukin-17 receptor signaling in the development of autoimmune glomerulonephritis. (Ramani K, Pawaria S, Maers K, Huppler AR, Gaffen SL, Biswas PS) J Leukoc Biol 2014 Sep;96(3):463-72 37 Citations |
2 | In vivo enrichment of genetically manipulated platelets corrects the murine hemophilic phenotype and induces immune tolerance even using a low multiplicity of infection. (Schroeder JA, Chen Y, Fang J, Wilcox DA, Shi Q) J Thromb Haemost 2014 Aug;12(8):1283-93 31 Citations |
1 | Effects of novel isoform-selective phosphoinositide 3-kinase inhibitors on natural killer cell function. (Yea SS, So L, Mallya S, Lee J, Rajasekaran K, Malarkannan S, Fruman DA) PLoS One 2014;9(6):e99486 11 Citations |
3 | De novo expression of sodium-glucose cotransporter SGLT2 in Bowman's capsule coincides with replacement of parietal epithelial cell layer with proximal tubule-like epithelium. (Tabatabai NM, North PE, Regner KR, Kumar SN, Duris CB, Blodgett AB) J Membr Biol 2014 Aug;247(8):675-83 6 Citations |
1 | NrasG12D oncoprotein inhibits apoptosis of preleukemic cells expressing Cbfβ-SMMHC via activation of MEK/ERK axis. (Xue L, Pulikkan JA, Valk PJ, Castilla LH) Blood 2014 Jul 17;124(3):426-36 22 Citations |
1 | Allele compensation in tip60+/- mice rescues white adipose tissue function in vivo. (Gao Y, Hamers N, Rakhshandehroo M, Berger R, Lough J, Kalkhoven E) PLoS One 2014;9(5):e98343 3 Citations |
1 | Desmosterol in brain is elevated because DHCR24 needs REST for Robust Expression but REST is poorly expressed. (Tint GS, Pan L, Shang Q, Sharpe LJ, Brown AJ, Li M, Yu H) Dev Neurosci 2014;36(2):132-42 3 Citations |
1 | Clodronate inhibits tumor angiogenesis in mouse models of ovarian cancer. (Reusser NM, Dalton HJ, Pradeep S, Gonzalez-Villasana V, Jennings NB, Vasquez HG, Wen Y, Rupaimoole R, Nagaraja AS, Gharpure K, Miyake T, Huang J, Hu W, Lopez-Berestein G, Sood AK) Cancer Biol Ther 2014 Aug;15(8):1061-7 32 Citations |
1 | Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage. (Schwab L, Goroncy L, Palaniyandi S, Gautam S, Triantafyllopoulou A, Mocsai A, Reichardt W, Karlsson FJ, Radhakrishnan SV, Hanke K, Schmitt-Graeff A, Freudenberg M, von Loewenich FD, Wolf P, Leonhardt F, Baxan N, Pfeifer D, Schmah O, Schönle A, Martin SF, Mertelsmann R, Duyster J, Finke J, Prinz M, Henneke P, Häcker H, Hildebrandt GC, Häcker G, Zeiser R) Nat Med 2014 Jun;20(6):648-54 207 Citations |
1 | Cited2 is required in trophoblasts for correct placental capillary patterning. (Moreau JL, Artap ST, Shi H, Chapman G, Leone G, Sparrow DB, Dunwoodie SL) Dev Biol 2014 Aug 01;392(1):62-79 34 Citations |
1 | Rapid tolerance induction by hematopoietic progenitor cells in the absence of donor-matched lymphoid cells. (Domen J, Li Y, Sun L, Simpson P, Gandy K) Transpl Immunol 2014 Aug;31(2):112-8 1 Citation |
1 | Cyclin-dependent kinase 5 in the ventral tegmental area regulates depression-related behaviors. (Zhong P, Liu X, Zhang Z, Hu Y, Liu SJ, Lezama-Ruiz M, Joksimovic M, Liu QS) J Neurosci 2014 Apr 30;34(18):6352-66 44 Citations |
1 | Intermittent cold exposure enhances fat accumulation in mice. (Yoo HS, Qiao L, Bosco C, Leong LH, Lytle N, Feng GS, Chi NW, Shao J) PLoS One 2014;9(5):e96432 27 Citations |
1 | Depletion of M2-like tumor-associated macrophages delays cutaneous T-cell lymphoma development in vivo. (Wu X, Schulte BC, Zhou Y, Haribhai D, Mackinnon AC, Plaza JA, Williams CB, Hwang ST) J Invest Dermatol 2014 Nov;134(11):2814-2822 101 Citations |
1 | A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis). (Kager LM, Wiersinga WJ, Roelofs JJ, de Boer OJ, Weiler H, van 't Veer C, van der Poll T) PLoS Negl Trop Dis 2014 Apr;8(4):e2819 9 Citations |
4 | New role for Kruppel-like factor 14 as a transcriptional activator involved in the generation of signaling lipids. (de Assuncao TM, Lomberk G, Cao S, Yaqoob U, Mathison A, Simonetto DA, Huebert RC, Urrutia RA, Shah VH) J Biol Chem 2014 May 30;289(22):15798-809 42 Citations |
1 | O-GlcNAcylation stabilizes β-catenin through direct competition with phosphorylation at threonine 41. (Olivier-Van Stichelen S, Dehennaut V, Buzy A, Zachayus JL, Guinez C, Mir AM, El Yazidi-Belkoura I, Copin MC, Boureme D, Loyaux D, Ferrara P, Lefebvre T) FASEB J 2014 Aug;28(8):3325-38 112 Citations |
1 | TPL2 kinase regulates the inflammatory milieu of the myeloma niche. (Hope C, Ollar SJ, Heninger E, Hebron E, Jensen JL, Kim J, Maroulakou I, Miyamoto S, Leith C, Yang DT, Callander N, Hematti P, Chesi M, Bergsagel PL, Asimakopoulos F) Blood 2014 May 22;123(21):3305-15 78 Citations |
1 | Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells. (Mboko WP, Mounce BC, Emmer J, Darrah E, Patel SB, Tarakanova VL) J Virol 2014 Jun;88(12):6993-7004 47 Citations |
3 | A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII. (Fahs SA, Hille MT, Shi Q, Weiler H, Montgomery RR) Blood 2014 Jun 12;123(24):3706-13 132 Citations |
1 | Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons. (Ivics Z, Mátés L, Yau TY, Landa V, Zidek V, Bashir S, Hoffmann OI, Hiripi L, Garrels W, Kues WA, Bösze Z, Geurts A, Pravenec M, Rülicke T, Izsvák Z) Nat Protoc 2014 Apr;9(4):773-93 55 Citations |
1 | Varied manifestations of persistent hyperplastic primary vitreous with graded somatic mosaic deletion of a single gene. (Mary-Sinclair MN, Wang X, Swanson DJ, Sung CY, Mendonca EA, Wroblewski K, Baumer SH, Goldowitz D, Jablonski MM, Skapek SX) Mol Vis 2014;20:215-30 3 Citations |
1 | Anion exchange HPLC isolation of high-density lipoprotein (HDL) and on-line estimation of proinflammatory HDL. (Ji X, Xu H, Zhang H, Hillery CA, Gao HQ, Pritchard KA Jr) PLoS One 2014;9(3):e91089 14 Citations |
1 | Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis. (Khan S, Abu Jawdeh BG, Goel M, Schilling WP, Parker MD, Puchowicz MA, Yadav SP, Harris RC, El-Meanawy A, Hoshi M, Shinlapawittayatorn K, Deschênes I, Ficker E, Schelling JR) J Clin Invest 2014 Mar;124(3):1057-68 45 Citations |
2 | Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression. (German AE, Mammoto T, Jiang E, Ingber DE, Mammoto A) J Cell Sci 2014 Apr 15;127(Pt 8):1672-83 36 Citations |
1 | Opposing roles of smooth muscle BK channels and ryanodine receptors in the regulation of nerve-evoked constriction of mesenteric resistance arteries. (Krishnamoorthy G, Sonkusare SK, Heppner TJ, Nelson MT) Am J Physiol Heart Circ Physiol 2014 Apr 01;306(7):H981-8 15 Citations |
1 | Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. (Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, Manichaikul A, Davis B, Lohman K, Joon AY, Smith AV, Grove ML, Zanoni P, Redon V, Demissie S, Lawson K, Peters U, Carlson C, Jackson RD, Ryckman KK, Mackey RH, Robinson JG, Siscovick DS, Schreiner PJ, Mychaleckyj JC, Pankow JS, Hofman A, Uitterlinden AG, Harris TB, Taylor KD, Stafford JM, Reynolds LM, Marioni RE, Dehghan A, Franco OH, Patel AP, Lu Y, Hindy G, Gottesman O, Bottinger EP, Melander O, Orho-Melander M, Loos RJ, Duga S, Merlini PA, Farrall M, Goel A, Asselta R, Girelli D, Martinelli N, Shah SH, Kraus WE, Li M, Rader DJ, Reilly MP, McPherson R, Watkins H, Ardissino D, NHLBI GO Exome Sequencing Project, Zhang Q, Wang J, Tsai MY, Taylor HA, Correa A, Griswold ME, Lange LA, Starr JM, Rudan I, Eiriksdottir G, Launer LJ, Ordovas JM, Levy D, Chen YD, Reiner AP, Hayward C, Polasek O, Deary IJ, Borecki IB, Liu Y, Gudnason V, Wilson JG, van Duijn CM, Kooperberg C, Rich SS, Psaty BM, Rotter JI, O'Donnell CJ, Rice K, Boerwinkle E, Kathiresan S, Cupples LA) Am J Hum Genet 2014 Feb 06;94(2):223-32 252 Citations |
1 | Safety and chemopreventive effect of Polyphenon E in preventing early and metastatic progression of prostate cancer in TRAMP mice. (Kim SJ, Amankwah E, Connors S, Park HY, Rincon M, Cornnell H, Chornokur G, Hashim AI, Choi J, Tsai YY, Engelman RW, Kumar N, Park JY) Cancer Prev Res (Phila) 2014 Apr;7(4):435-44 20 Citations |
1 | Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling. (Zhong P, Wang W, Pan B, Liu X, Zhang Z, Long JZ, Zhang HT, Cravatt BF, Liu QS) Neuropsychopharmacology 2014 Jun;39(7):1763-76 107 Citations |
1 | Role of neutrophils in IL-17-dependent immunity to mucosal candidiasis. (Huppler AR, Conti HR, Hernández-Santos N, Darville T, Biswas PS, Gaffen SL) J Immunol 2014 Feb 15;192(4):1745-52 100 Citations |
1 | Epicardial GATA factors regulate early coronary vascular plexus formation. (Kolander KD, Holtz ML, Cossette SM, Duncan SA, Misra RP) Dev Biol 2014 Feb 01;386(1):204-15 9 Citations |
1 | The adaptor CARD9 is required for adaptive but not innate immunity to oral mucosal Candida albicans infections. (Bishu S, Hernández-Santos N, Simpson-Abelson MR, Huppler AR, Conti HR, Ghilardi N, Mamo AJ, Gaffen SL) Infect Immun 2014 Mar;82(3):1173-80 50 Citations |
1 | HDAC inhibitors restore the capacity of aged mice to respond to haloperidol through modulation of histone acetylation. (Montalvo-Ortiz JL, Keegan J, Gallardo C, Gerst N, Tetsuka K, Tucker C, Matsumoto M, Fang D, Csernansky JG, Dong H) Neuropsychopharmacology 2014 May;39(6):1469-78 17 Citations |
5 | B-cell tolerance regulates production of antibodies causing heparin-induced thrombocytopenia. (Zheng Y, Wang AW, Yu M, Padmanabhan A, Tourdot BE, Newman DK, White GC, Aster RH, Wen R, Wang D) Blood 2014 Feb 06;123(6):931-4 42 Citations |
1 | Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection. (Mounce BC, Mboko WP, Kanack AJ, Tarakanova VL) J Virol 2014 Feb;88(4):2268-78 17 Citations |
2 | Hepatic apolipoprotein M (apoM) overexpression stimulates formation of larger apoM/sphingosine 1-phosphate-enriched plasma high density lipoprotein. (Liu M, Seo J, Allegood J, Bi X, Zhu X, Boudyguina E, Gebre AK, Avni D, Shah D, Sorci-Thomas MG, Thomas MJ, Shelness GS, Spiegel S, Parks JS) J Biol Chem 2014 Jan 31;289(5):2801-14 60 Citations |
1 | Mechanical sensitization of cutaneous sensory fibers in the spared nerve injury mouse model. (Smith AK, O'Hara CL, Stucky CL) Mol Pain 2013 Nov 29;9:61 48 Citations |
1 | Localized interleukin-12 delivery for immunotherapy of solid tumours. (Wei LZ, Xu Y, Nelles EM, Furlonger C, Wang JC, Di Grappa MA, Khokha R, Medin JA, Paige CJ) J Cell Mol Med 2013 Nov;17(11):1465-74 14 Citations |
1 | Proteasome proteolysis supports stimulated platelet function and thrombosis. (Gupta N, Li W, Willard B, Silverstein RL, McIntyre TM) Arterioscler Thromb Vasc Biol 2014 Jan;34(1):160-8 46 Citations |
1 | Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice. (Yokota N, Zarpellon A, Chakrabarty S, Bogdanov VY, Gruber A, Castellino FJ, Mackman N, Ellies LG, Weiler H, Ruggeri ZM, Ruf W) J Thromb Haemost 2014 Jan;12(1):71-81 28 Citations |
2 | Role of macrophage PPARγ in experimental hypertension. (Kriska T, Cepura C, Gauthier KM, Campbell WB) Am J Physiol Heart Circ Physiol 2014 Jan 01;306(1):H26-32 5 Citations |
4 | Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression. (Schmitt EG, Haribhai D, Jeschke JC, Co DO, Ziegelbauer J, Yan K, Iwakura Y, Mishra MK, Simpson P, Salzman NH, Williams CB) J Immunol 2013 Dec 01;191(11):5460-76 4 Citations |
1 | HMGB1 recruits hepatic stellate cells and liver endothelial cells to sites of ethanol-induced parenchymal cell injury. (Seo YS, Kwon JH, Yaqoob U, Yang L, De Assuncao TM, Simonetto DA, Verma VK, Shah VH) Am J Physiol Gastrointest Liver Physiol 2013 Dec;305(11):G838-48 43 Citations |
1 | Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy. (Bouchlaka MN, Sckisel GD, Chen M, Mirsoian A, Zamora AE, Maverakis E, Wilkins DE, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Redelman D, Taub DD, Murphy WJ) J Exp Med 2013 Oct 21;210(11):2223-37 113 Citations |
1 | Suprachiasmatic astrocytes modulate the circadian clock in response to TNF-α. (Duhart JM, Leone MJ, Paladino N, Evans JA, Castanon-Cervantes O, Davidson AJ, Golombek DA) J Immunol 2013 Nov 01;191(9):4656-64 53 Citations |
1 | Circadian rhythm of contrast sensitivity is regulated by a dopamine-neuronal PAS-domain protein 2-adenylyl cyclase 1 signaling pathway in retinal ganglion cells. (Hwang CK, Chaurasia SS, Jackson CR, Chan GC, Storm DR, Iuvone PM) J Neurosci 2013 Sep 18;33(38):14989-97 54 Citations |
1 | The memory-enhancing effects of hippocampal estrogen receptor activation involve metabotropic glutamate receptor signaling. (Boulware MI, Heisler JD, Frick KM) J Neurosci 2013 Sep 18;33(38):15184-94 161 Citations |
1 | Direct calorimetry identifies deficiencies in respirometry for the determination of resting metabolic rate in C57Bl/6 and FVB mice. (Burnett CM, Grobe JL) Am J Physiol Endocrinol Metab 2013 Oct 01;305(7):E916-24 34 Citations |
1 | Mice with a targeted disruption of Slc4a11 model the progressive corneal changes of congenital hereditary endothelial dystrophy. (Han SB, Ang HP, Poh R, Chaurasia SS, Peh G, Liu J, Tan DT, Vithana EN, Mehta JS) Invest Ophthalmol Vis Sci 2013 Sep 27;54(9):6179-89 47 Citations |
1 | Lactate administration reproduces specific brain and liver exercise-related changes. (E L, Lu J, Selfridge JE, Burns JM, Swerdlow RH) J Neurochem 2013 Oct;127(1):91-100 83 Citations |
1 | Environmental circadian disruption elevates the IL-6 response to lipopolysaccharide in blood. (Adams KL, Castanon-Cervantes O, Evans JA, Davidson AJ) J Biol Rhythms 2013 Aug;28(4):272-7 47 Citations |
2 | Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia. (Kanaji T, Kanaji S, Montgomery RR, Patel SB, Newman PJ) Blood 2013 Oct 10;122(15):2732-42 47 Citations |
1 | Sepiapterin ameliorates chemically induced murine colitis and azoxymethane-induced colon cancer. (Cardnell RJ, Rabender CS, Ross GR, Guo C, Howlett EL, Alam A, Wang XY, Akbarali HI, Mikkelsen RB) J Pharmacol Exp Ther 2013 Oct;347(1):117-25 16 Citations |
1 | Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice. (Haarberg KM, Li J, Heinrichs J, Wang D, Liu C, Bronk CC, Kaosaard K, Owyang AM, Holland S, Masuda E, Tso K, Blazar BR, Anasetti C, Beg AA, Yu XZ) Blood 2013 Oct 03;122(14):2500-11 35 Citations |
1 | Canonical Wnt signaling is necessary for object recognition memory consolidation. (Fortress AM, Schram SL, Tuscher JJ, Frick KM) J Neurosci 2013 Jul 31;33(31):12619-26 94 Citations |
1 | Thrombospondin-1 modulates VEGF signaling via CD36 by recruiting SHP-1 to VEGFR2 complex in microvascular endothelial cells. (Chu LY, Ramakrishnan DP, Silverstein RL) Blood 2013 Sep 05;122(10):1822-32 110 Citations |
1 | Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. (Hou P, Li Y, Zhang X, Liu C, Guan J, Li H, Zhao T, Ye J, Yang W, Liu K, Ge J, Xu J, Zhang Q, Zhao Y, Deng H) Science 2013 Aug 09;341(6146):651-4 1080 Citations |
1 | Antagonistic regulation by the transcription factors C/EBPα and MITF specifies basophil and mast cell fates. (Qi X, Hong J, Chaves L, Zhuang Y, Chen Y, Wang D, Chabon J, Graham B, Ohmori K, Li Y, Huang H) Immunity 2013 Jul 25;39(1):97-110 107 Citations |
1 | Engineering lentiviral vectors for modulation of dendritic cell apoptotic pathways. (Wang JC, Felizardo TC, Au BC, Fowler DH, Dekaban GA, Medin JA) Virol J 2013 Jul 20;10:240 9 Citations |
1 | The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity. (Wang Y, Shaked I, Stanford SM, Zhou W, Curtsinger JM, Mikulski Z, Shaheen ZR, Cheng G, Sawatzke K, Campbell AM, Auger JL, Bilgic H, Shoyama FM, Schmeling DO, Balfour HH Jr, Hasegawa K, Chan AC, Corbett JA, Binstadt BA, Mescher MF, Ley K, Bottini N, Peterson EJ) Immunity 2013 Jul 25;39(1):111-22 153 Citations |
1 | Tcf19 is a novel islet factor necessary for proliferation and survival in the INS-1 β-cell line. (Krautkramer KA, Linnemann AK, Fontaine DA, Whillock AL, Harris TW, Schleis GJ, Truchan NA, Marty-Santos L, Lavine JA, Cleaver O, Kimple ME, Davis DB) Am J Physiol Endocrinol Metab 2013 Sep 01;305(5):E600-10 26 Citations |
2 | Extracellular matrix structure and tissue stiffness control postnatal lung development through the lipoprotein receptor-related protein 5/Tie2 signaling system. (Mammoto T, Jiang E, Jiang A, Mammoto A) Am J Respir Cell Mol Biol 2013 Dec;49(6):1009-18 55 Citations |
2 | Photobiomodulation induced by 670 nm light ameliorates MOG35-55 induced EAE in female C57BL/6 mice: a role for remediation of nitrosative stress. (Muili KA, Gopalakrishnan S, Eells JT, Lyons JA) PLoS One 2013;8(6):e67358 34 Citations |
1 | Murine NK-cell licensing is reflective of donor MHC-I following allogeneic hematopoietic stem cell transplantation in murine cytomegalovirus responses. (Sungur CM, Tang-Feldman YJ, Zamora AE, Alvarez M, Pomeroy C, Murphy WJ) Blood 2013 Aug 22;122(8):1518-21 21 Citations |
1 | Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells. (Han SS, Tompkins VS, Son DJ, Kamberos NL, Stunz LL, Halwani A, Bishop GA, Janz S) Biochem Biophys Res Commun 2013 Jul 12;436(4):660-5 23 Citations |
1 | A mouse model of corneal endothelial decompensation using cryoinjury. (Han SB, Ang H, Balehosur D, Peh G, Chaurasia SS, Tan DT, Mehta JS) Mol Vis 2013;19:1222-30 25 Citations |
1 | Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice. (Li J, Heinrichs J, Leconte J, Haarberg K, Semple K, Liu C, Gigoux M, Kornete M, Piccirillo CA, Suh WK, Yu XZ) J Immunol 2013 Jul 01;191(1):200-7 20 Citations |
1 | The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. (Yang XO, Zhang H, Kim BS, Niu X, Peng J, Chen Y, Kerketta R, Lee YH, Chang SH, Corry DB, Wang D, Watowich SS, Dong C) Nat Immunol 2013 Jul;14(7):732-40 106 Citations |
1 | c-Rel is an essential transcription factor for the development of acute graft-versus-host disease in mice. (Yu Y, Wang D, Kaosaard K, Liu C, Fu J, Haarberg K, Anasetti C, Beg AA, Yu XZ) Eur J Immunol 2013 Sep;43(9):2327-37 19 Citations |
1 | Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy. (Ottenheijm CA, Buck D, de Winter JM, Ferrara C, Piroddi N, Tesi C, Jasper JR, Malik FI, Meng H, Stienen GJ, Beggs AH, Labeit S, Poggesi C, Lawlor MW, Granzier H) Brain 2013 Jun;136(Pt 6):1718-31 51 Citations |
1 | Far red/near infrared light treatment promotes femoral artery collateralization in the ischemic hindlimb. (Lohr NL, Ninomiya JT, Warltier DC, Weihrauch D) J Mol Cell Cardiol 2013 Sep;62:36-42 19 Citations |
1 | Apolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia. (Baotic I, Ge ZD, Sedlic F, Coon A, Weihrauch D, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2013 Jul 15;305(2):H219-27 18 Citations |
2 | Platelet rich plasma extract promotes angiogenesis through the angiopoietin1-Tie2 pathway. (Mammoto T, Jiang A, Jiang E, Mammoto A) Microvasc Res 2013 Sep;89:15-24 84 Citations |
1 | A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain. (Tsunozaki M, Lennertz RC, Vilceanu D, Katta S, Stucky CL, Bautista DM) J Physiol 2013 Jul 01;591(13):3325-40 65 Citations |
1 | Molecular basis of antiangiogenic thrombospondin-1 type 1 repeat domain interactions with CD36. (Klenotic PA, Page RC, Li W, Amick J, Misra S, Silverstein RL) Arterioscler Thromb Vasc Biol 2013 Jul;33(7):1655-62 35 Citations |
2 | A conserved gammaherpesvirus protein kinase targets histone deacetylases 1 and 2 to facilitate viral replication in primary macrophages. (Mounce BC, Mboko WP, Bigley TM, Terhune SS, Tarakanova VL) J Virol 2013 Jul;87(13):7314-25 13 Citations |
1 | Lentivirus IL-10 gene therapy down-regulates IL-17 and attenuates mouse orthotopic lung allograft rejection. (Hirayama S, Sato M, Loisel-Meyer S, Matsuda Y, Oishi H, Guan Z, Saito T, Yeung J, Cypel M, Hwang DM, Medin JA, Liu M, Keshavjee S) Am J Transplant 2013 Jun;13(6):1586-93 39 Citations |
1 | Fluorescence endoscopy of cathepsin activity discriminates dysplasia from colitis. (Gounaris E, Martin J, Ishihara Y, Khan MW, Lee G, Sinh P, Chen EZ, Angarone M, Weissleder R, Khazaie K, Barrett TA) Inflamm Bowel Dis 2013 Jun;19(7):1339-45 38 Citations |
1 | CXCR4 negatively regulates keratinocyte proliferation in IL-23-mediated psoriasiform dermatitis. (Takekoshi T, Wu X, Mitsui H, Tada Y, Kao MC, Sato S, Dwinell MB, Hwang ST) J Invest Dermatol 2013 Nov;133(11):2530-2537 21 Citations |
2 | A critical role for the retinoic acid signaling pathway in the pathophysiology of gastrointestinal graft-versus-host disease. (Chen X, Dodge J, Komorowski R, Drobyski WR) Blood 2013 May 09;121(19):3970-80 26 Citations |
2 | Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. (Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ, Kreisel D, Swartz MA, Sorci-Thomas MG, Randolph GJ) J Clin Invest 2013 Apr;123(4):1571-9 246 Citations |
1 | IL12B expression is sustained by a heterogenous population of myeloid lineages during tuberculosis. (Reeme AE, Miller HE, Robinson RT) Tuberculosis (Edinb) 2013 May;93(3):343-56 7 Citations |
1 | Molecular mechanism of transglutaminase-2 in corneal epithelial migration and adhesion. (Tong L, Png E, Aihua H, Yong SS, Yeo HL, Riau A, Mendoz E, Chaurasia SS, Lim CT, Yiu TW, Iismaa SE) Biochim Biophys Acta 2013 Jun;1833(6):1304-15 20 Citations |
1 | Adenosine transporter ENT1 regulates the acquisition of goal-directed behavior and ethanol drinking through A2A receptor in the dorsomedial striatum. (Nam HW, Hinton DJ, Kang NY, Kim T, Lee MR, Oliveros A, Adams C, Ruby CL, Choi DS) J Neurosci 2013 Mar 06;33(10):4329-38 83 Citations |
1 | Pulmonary inflammation after ethanol exposure and burn injury is attenuated in the absence of IL-6. (Chen MM, Bird MD, Zahs A, Deburghgraeve C, Posnik B, Davis CS, Kovacs EJ) Alcohol 2013 May;47(3):223-9 25 Citations |
4 | Critical role for mouse marginal zone B cells in PF4/heparin antibody production. (Zheng Y, Yu M, Podd A, Yuan L, Newman DK, Wen R, Arepally G, Wang D) Blood 2013 Apr 25;121(17):3484-92 40 Citations |
1 | Prolonged treatment with angiotensin 1-7 improves endothelial function in diet-induced obesity. (Beyer AM, Guo DF, Rahmouni K) J Hypertens 2013 Apr;31(4):730-8 35 Citations |
1 | Estradiol-induced object recognition memory consolidation is dependent on activation of mTOR signaling in the dorsal hippocampus. (Fortress AM, Fan L, Orr PT, Zhao Z, Frick KM) Learn Mem 2013 Feb 19;20(3):147-55 123 Citations |
1 | Reduction in ATP levels triggers immunoproteasome activation by the 11S (PA28) regulator during early antiviral response mediated by IFNβ in mouse pancreatic β-cells. (Freudenburg W, Gautam M, Chakraborty P, James J, Richards J, Salvatori AS, Baldwin A, Schriewer J, Buller RM, Corbett JA, Skowyra D) PLoS One 2013;8(2):e52408 22 Citations |
1 | Epidermal growth factor regulates hematopoietic regeneration after radiation injury. (Doan PL, Himburg HA, Helms K, Russell JL, Fixsen E, Quarmyne M, Harris JR, Deoliviera D, Sullivan JM, Chao NJ, Kirsch DG, Chute JP) Nat Med 2013 Mar;19(3):295-304 143 Citations |
2 | Heparin rescues factor V Leiden-associated placental failure independent of anticoagulation in a murine high-risk pregnancy model. (An J, Waitara MS, Bordas M, Arumugam V, Hoffmann RG, Petrich BG, Sinha U, North PE, Sood R) Blood 2013 Mar 14;121(11):2127-34 17 Citations |
1 | Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans. (Ahn SH, Tsalik EL, Cyr DD, Zhang Y, van Velkinburgh JC, Langley RJ, Glickman SW, Cairns CB, Zaas AK, Rivers EP, Otero RM, Veldman T, Kingsmore SF, Lucas J, Woods CW, Ginsburg GS, Fowler VG Jr) PLoS One 2013;8(1):e48979 42 Citations |
1 | Selenoprotein N deficiency in mice is associated with abnormal lung development. (Moghadaszadeh B, Rider BE, Lawlor MW, Childers MK, Grange RW, Gupta K, Boukedes SS, Owen CA, Beggs AH) FASEB J 2013 Apr;27(4):1585-99 30 Citations |
1 | Preconditioning by isoflurane elicits mitochondrial protective mechanisms independent of sarcolemmal KATP channel in mouse cardiomyocytes. (Muravyeva M, Sedlic F, Dolan N, Bosnjak ZJ, Stadnicka A) J Cardiovasc Pharmacol 2013 May;61(5):369-77 4 Citations |
2 | Modulation of B-cell tolerance by murine gammaherpesvirus 68 infection: requirement for Orf73 viral gene expression and follicular helper T cells. (Gauld SB, De Santis JL, Kulinski JM, McGraw JA, Leonardo SM, Ruder EA, Maier W, Tarakanova VL) Immunology 2013 Jun;139(2):197-204 15 Citations |
1 | Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanisms. (Yu Y, Cho HI, Wang D, Kaosaard K, Anasetti C, Celis E, Yu XZ) J Immunol 2013 Feb 15;190(4):1873-81 51 Citations |
1 | Ferric chloride-induced murine carotid arterial injury: A model of redox pathology. (Li W, McIntyre TM, Silverstein RL) Redox Biol 2013;1(1):50-5 70 Citations |
1 | Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE. (Christy AL, Walker ME, Hessner MJ, Brown MA) J Autoimmun 2013 May;42:50-61 127 Citations |
3 | Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo. (Zhi H, Rauova L, Hayes V, Gao C, Boylan B, Newman DK, McKenzie SE, Cooley BC, Poncz M, Newman PJ) Blood 2013 Mar 07;121(10):1858-67 77 Citations |
1 | Nematode asparaginyl-tRNA synthetase resolves intestinal inflammation in mice with T-cell transfer colitis. (Kron MA, Metwali A, Vodanovic-Jankovic S, Elliott D) Clin Vaccine Immunol 2013 Feb;20(2):276-81 35 Citations |
3 | 4F decreases IRF5 expression and activation in hearts of tight skin mice. (Xu H, Krolikowski JG, Jones DW, Ge ZD, Pagel PS, Pritchard KA Jr, Weihrauch D) PLoS One 2012;7(12):e52046 12 Citations |
1 | Th17 cells confer long-term adaptive immunity to oral mucosal Candida albicans infections. (Hernández-Santos N, Huppler AR, Peterson AC, Khader SA, McKenna KC, Gaffen SL) Mucosal Immunol 2013 Sep;6(5):900-10 143 Citations |
1 | Painting blood vessels and atherosclerotic plaques with an adhesive drug depot. (Kastrup CJ, Nahrendorf M, Figueiredo JL, Lee H, Kambhampati S, Lee T, Cho SW, Gorbatov R, Iwamoto Y, Dang TT, Dutta P, Yeon JH, Cheng H, Pritchard CD, Vegas AJ, Siegel CD, MacDougall S, Okonkwo M, Thai A, Stone JR, Coury AJ, Weissleder R, Langer R, Anderson DG) Proc Natl Acad Sci U S A 2012 Dec 26;109(52):21444-9 111 Citations |
3 | Transient repetitive exposure to low level light therapy enhances collateral blood vessel growth in the ischemic hindlimb of the tight skin mouse. (Zaidi M, Krolikowki JG, Jones DW, Pritchard KA Jr, Struve J, Nandedkar SD, Lohr NL, Pagel PS, Weihrauch D) Photochem Photobiol 2013;89(3):709-13 17 Citations |
2 | Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries. (Siangjong L, Gauthier KM, Pfister SL, Smyth EM, Campbell WB) Am J Physiol Heart Circ Physiol 2013 Feb 01;304(3):H382-92 22 Citations |
3 | A novel model of spontaneous otitis media with effusion (OME) in the Oxgr1 knock-out mouse. (Kerschner JE, Hong W, Taylor SR, Kerschner JA, Khampang P, Wrege KC, North PE) Int J Pediatr Otorhinolaryngol 2013 Jan;77(1):79-84 24 Citations |
1 | Increased dietary intake of vitamin A promotes aortic valve calcification in vivo. (Huk DJ, Hammond HL, Kegechika H, Lincoln J) Arterioscler Thromb Vasc Biol 2013 Feb;33(2):285-93 27 Citations |
1 | Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein. (Shimizu A, Nakayama H, Wang P, König C, Akino T, Sandlund J, Coma S, Italiano JE Jr, Mammoto A, Bielenberg DR, Klagsbrun M) J Biol Chem 2013 Jan 25;288(4):2210-22 82 Citations |
1 | TRPA1 is functionally expressed primarily by IB4-binding, non-peptidergic mouse and rat sensory neurons. (Barabas ME, Kossyreva EA, Stucky CL) PLoS One 2012;7(10):e47988 85 Citations |
2 | A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia. (Hanson MS, Xu H, Flewelen TC, Holzhauer SL, Retherford D, Jones DW, Frei AC, Pritchard KA Jr, Hillery CA, Hogg N, Wandersee NJ) Am J Physiol Heart Circ Physiol 2013 Jan 15;304(2):H328-36 11 Citations |
1 | Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation. (Ulland TK, Janowski AM, Buchan BW, Faron M, Cassel SL, Jones BD, Sutterwala FS) Infect Immun 2013 Jan;81(1):201-8 13 Citations |
1 | Anti-inflammatory and neuroprotective effects of an orally active apocynin derivative in pre-clinical models of Parkinson's disease. (Ghosh A, Kanthasamy A, Joseph J, Anantharam V, Srivastava P, Dranka BP, Kalyanaraman B, Kanthasamy AG) J Neuroinflammation 2012 Oct 23;9:241 93 Citations |
1 | Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche. (Himburg HA, Harris JR, Ito T, Daher P, Russell JL, Quarmyne M, Doan PL, Helms K, Nakamura M, Fixsen E, Herradon G, Reya T, Chao NJ, Harroch S, Chute JP) Cell Rep 2012 Oct 25;2(4):964-75 75 Citations |
1 | Toll-like receptor 2 ligands promote microglial cell death by inducing autophagy. (Arroyo DS, Soria JA, Gaviglio EA, Garcia-Keller C, Cancela LM, Rodriguez-Galan MC, Wang JM, Iribarren P) FASEB J 2013 Jan;27(1):299-312 41 Citations |
1 | Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia. (Liu SQ, Tefft BJ, Roberts DT, Zhang LQ, Ren Y, Li YC, Huang Y, Zhang D, Phillips HR, Wu YH) Am J Physiol Heart Circ Physiol 2012 Dec 15;303(12):H1446-58 55 Citations |
1 | Striatal adenosine signaling regulates EAAT2 and astrocytic AQP4 expression and alcohol drinking in mice. (Lee MR, Ruby CL, Hinton DJ, Choi S, Adams CA, Young Kang N, Choi DS) Neuropsychopharmacology 2013 Feb;38(3):437-45 52 Citations |
1 | Neonatal transfer of membrane-bound stem cell factor improves survival and heart function in aged mice after myocardial ischemia. (Sun Z, Lee CJ, Mejia-Guerrero S, Zhang Y, Higuchi K, Li RK, Medin JA) Hum Gene Ther 2012 Dec;23(12):1280-9 4 Citations |
1 | Precise control of osteogenesis for craniofacial defect repair: the role of direct osteoprogenitor contact in BMP-2-based bioprinting. (Smith DM, Cray JJ Jr, Weiss LE, Dai Fei EK, Shakir S, Rottgers SA, Losee JE, Campbell PG, Cooper GM) Ann Plast Surg 2012 Oct;69(4):485-8 22 Citations |
2 | PPARγ regulates resistance vessel tone through a mechanism involving RGS5-mediated control of protein kinase C and BKCa channel activity. (Ketsawatsomkron P, Lorca RA, Keen HL, Weatherford ET, Liu X, Pelham CJ, Grobe JL, Faraci FM, England SK, Sigmund CD) Circ Res 2012 Nov 09;111(11):1446-58 53 Citations |
1 | Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis. (Neal MD, Sodhi CP, Jia H, Dyer M, Egan CE, Yazji I, Good M, Afrazi A, Marino R, Slagle D, Ma C, Branca MF, Prindle T Jr, Grant Z, Ozolek J, Hackam DJ) J Biol Chem 2012 Oct 26;287(44):37296-308 166 Citations |
1 | The TCR repertoires of regulatory and conventional T cells specific for the same foreign antigen are distinct. (Relland LM, Williams JB, Relland GN, Haribhai D, Ziegelbauer J, Yassai M, Gorski J, Williams CB) J Immunol 2012 Oct 01;189(7):3566-74 23 Citations |
1 | TRPA1 mediates mechanical sensitization in nociceptors during inflammation. (Lennertz RC, Kossyreva EA, Smith AK, Stucky CL) PLoS One 2012;7(8):e43597 127 Citations |
1 | Dps promotes survival of nontypeable Haemophilus influenzae in biofilm communities in vitro and resistance to clearance in vivo. (Pang B, Hong W, Kock ND, Swords WE) Front Cell Infect Microbiol 2012;2:58 23 Citations |
2 | Factor VIII inhibitors: von Willebrand factor makes a difference in vitro and in vivo. (Shi Q, Kuether EL, Schroeder JA, Perry CL, Fahs SA, Cox Gill J, Montgomery RR) J Thromb Haemost 2012 Nov;10(11):2328-37 18 Citations |
1 | The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin. (Gantner BN, Jin H, Qian F, Hay N, He B, Ye RD) J Immunol 2012 Sep 15;189(6):3104-11 29 Citations |
1 | A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability. (Takekoshi T, Ziarek JJ, Volkman BF, Hwang ST) Mol Cancer Ther 2012 Nov;11(11):2516-25 49 Citations |
1 | p53 mediates TNF-induced epithelial cell apoptosis in IBD. (Goretsky T, Dirisina R, Sinh P, Mittal N, Managlia E, Williams DB, Posca D, Ryu H, Katzman RB, Barrett TA) Am J Pathol 2012 Oct;181(4):1306-15 80 Citations |
1 | Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected joint tissue. (Lochhead RB, Sonderegger FL, Ma Y, Brewster JE, Cornwall D, Maylor-Hagen H, Miller JC, Zachary JF, Weis JH, Weis JJ) J Immunol 2012 Sep 01;189(5):2488-501 30 Citations |
2 | LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway. (Mammoto T, Chen J, Jiang E, Jiang A, Smith LE, Ingber DE, Mammoto A) PLoS One 2012;7(7):e41596 25 Citations |
1 | Myotubularin-deficient myoblasts display increased apoptosis, delayed proliferation, and poor cell engraftment. (Lawlor MW, Alexander MS, Viola MG, Meng H, Joubert R, Gupta V, Motohashi N, Manfready RA, Hsu CP, Huang P, Buj-Bello A, Kunkel LM, Beggs AH, Gussoni E) Am J Pathol 2012 Sep;181(3):961-8 34 Citations |
2 | Phospholipase Cγ2 plays a role in TCR signal transduction and T cell selection. (Fu G, Chen Y, Schuman J, Wang D, Wen R) J Immunol 2012 Sep 01;189(5):2326-32 18 Citations |
1 | Identification of nephropathy candidate genes by comparing sclerosis-prone and sclerosis-resistant mouse strain kidney transcriptomes. (El-Meanawy A, Schelling JR, Iyengar SK, Hayden P, Barathan S, Goddard K, Pozuelo F, Elashi E, Nair V, Kretzler M, Sedor JR) BMC Nephrol 2012 Jul 19;13:61 6 Citations |
1 | Expansion of follicular helper T cells in the absence of Treg cells: implications for loss of B-cell anergy. (Leonardo SM, De Santis JL, Gehrand A, Malherbe LP, Gauld SB) Eur J Immunol 2012 Oct;42(10):2597-607 22 Citations |
1 | Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure. (Hill MN, Kumar SA, Filipski SB, Iverson M, Stuhr KL, Keith JM, Cravatt BF, Hillard CJ, Chattarji S, McEwen BS) Mol Psychiatry 2013 Oct;18(10):1125-35 173 Citations |
1 | Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. (Korin N, Kanapathipillai M, Matthews BD, Crescente M, Brill A, Mammoto T, Ghosh K, Jurek S, Bencherif SA, Bhatta D, Coskun AU, Feldman CL, Wagner DD, Ingber DE) Science 2012 Aug 10;337(6095):738-42 421 Citations |
2 | The β₃-integrin ligand of Borrelia burgdorferi is critical for infection of mice but not ticks. (Ristow LC, Miller HE, Padmore LJ, Chettri R, Salzman N, Caimano MJ, Rosa PA, Coburn J) Mol Microbiol 2012 Sep;85(6):1105-18 48 Citations |
1 | Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. (Geiger H, Pawar SA, Kerschen EJ, Nattamai KJ, Hernandez I, Liang HP, Fernández JÁ, Cancelas JA, Ryan MA, Kustikova O, Schambach A, Fu Q, Wang J, Fink LM, Petersen KU, Zhou D, Griffin JH, Baum C, Weiler H, Hauer-Jensen M) Nat Med 2012 Jul;18(7):1123-9 94 Citations |
1 | Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury. (Cho N, Nguyen DH, Satkunendrarajah K, Branch DR, Fehlings MG) J Neuroinflammation 2012 Jun 20;9:134 26 Citations |
1 | Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion. (Park YM, Drazba JA, Vasanji A, Egelhoff T, Febbraio M, Silverstein RL) Mol Biol Cell 2012 Aug;23(16):3057-68 54 Citations |
1 | LBH589 enhances T cell activation in vivo and accelerates graft-versus-host disease in mice. (Wang D, Iclozan C, Liu C, Xia C, Anasetti C, Yu XZ) Biol Blood Marrow Transplant 2012 Aug;18(8):1182-1190.e1 23 Citations |
1 | Mitochondrial reactive oxygen species generation triggers inflammatory response and tissue injury associated with hepatic ischemia-reperfusion: therapeutic potential of mitochondrially targeted antioxidants. (Mukhopadhyay P, Horváth B, Zsengellėr Z, Bátkai S, Cao Z, Kechrid M, Holovac E, Erdėlyi K, Tanchian G, Liaudet L, Stillman IE, Joseph J, Kalyanaraman B, Pacher P) Free Radic Biol Med 2012 Sep 01;53(5):1123-38 113 Citations |
2 | CD8+ Foxp3+ regulatory T cells are induced during graft-versus-host disease and mitigate disease severity. (Beres AJ, Haribhai D, Chadwick AC, Gonyo PJ, Williams CB, Drobyski WR) J Immunol 2012 Jul 01;189(1):464-74 95 Citations |
2 | Contribution of platelet vs. endothelial VWF to platelet adhesion and hemostasis. (Kanaji S, Fahs SA, Shi Q, Haberichter SL, Montgomery RR) J Thromb Haemost 2012 Aug;10(8):1646-52 99 Citations |
3 | Lentivirus-mediated platelet gene therapy of murine hemophilia A with pre-existing anti-factor VIII immunity. (Kuether EL, Schroeder JA, Fahs SA, Cooley BC, Chen Y, Montgomery RR, Wilcox DA, Shi Q) J Thromb Haemost 2012 Aug;10(8):1570-80 90 Citations |
1 | Effect of exercise on mouse liver and brain bioenergetic infrastructures. (E L, Lu J, Burns JM, Swerdlow RH) Exp Physiol 2013 Jan;98(1):207-19 34 Citations |
1 | The origin and function of platelet glycosyltransferases. (Wandall HH, Rumjantseva V, Sørensen AL, Patel-Hett S, Josefsson EC, Bennett EP, Italiano JE Jr, Clausen H, Hartwig JH, Hoffmeister KM) Blood 2012 Jul 19;120(3):626-35 79 Citations |
2 | A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity. (Hilzendeger AM, Morgan DA, Brooks L, Dellsperger D, Liu X, Grobe JL, Rahmouni K, Sigmund CD, Mark AL) Am J Physiol Heart Circ Physiol 2012 Jul 15;303(2):H197-206 98 Citations |
1 | Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains. (Yuan R, Meng Q, Nautiyal J, Flurkey K, Tsaih SW, Krier R, Parker MG, Harrison DE, Paigen B) Proc Natl Acad Sci U S A 2012 May 22;109(21):8224-9 86 Citations |
1 | Gene trapping uncovers sex-specific mechanisms for upstream stimulatory factors 1 and 2 in angiotensinogen expression. (Park S, Liu X, Davis DR, Sigmund CD) Hypertension 2012 Jun;59(6):1212-9 12 Citations |
1 | Cutting edge: in the absence of regulatory T cells, a unique Th cell population expands and leads to a loss of B cell anergy. (Leonardo SM, De Santis JL, Malherbe LP, Gauld SB) J Immunol 2012 Jun 01;188(11):5223-6 13 Citations |
3 | Cadherin 6 has a functional role in platelet aggregation and thrombus formation. (Dunne E, Spring CM, Reheman A, Jin W, Berndt MC, Newman DK, Newman PJ, Ni H, Kenny D) Arterioscler Thromb Vasc Biol 2012 Jul;32(7):1724-31 48 Citations |
1 | Krüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract. (Blackmore MG, Wang Z, Lerch JK, Motti D, Zhang YP, Shields CB, Lee JK, Goldberg JL, Lemmon VP, Bixby JL) Proc Natl Acad Sci U S A 2012 May 08;109(19):7517-22 213 Citations |
2 | Atypical E2F repressors and activators coordinate placental development. (Ouseph MM, Li J, Chen HZ, Pécot T, Wenzel P, Thompson JC, Comstock G, Chokshi V, Byrne M, Forde B, Chong JL, Huang K, Machiraju R, de Bruin A, Leone G) Dev Cell 2012 Apr 17;22(4):849-62 74 Citations |
1 | Cisplatin nephrotoxicity involves mitochondrial injury with impaired tubular mitochondrial enzyme activity. (Zsengellér ZK, Ellezian L, Brown D, Horváth B, Mukhopadhyay P, Kalyanaraman B, Parikh SM, Karumanchi SA, Stillman IE, Pacher P) J Histochem Cytochem 2012 Jul;60(7):521-9 96 Citations |
2 | Coordinate regulation of DNA damage and type I interferon responses imposes an antiviral state that attenuates mouse gammaherpesvirus type 68 replication in primary macrophages. (Mboko WP, Mounce BC, Wood BM, Kulinski JM, Corbett JA, Tarakanova VL) J Virol 2012 Jun;86(12):6899-912 22 Citations |
1 | Emergence of T cells that recognize nonpolymorphic antigens during graft-versus- host disease. (Rangarajan H, Yassai M, Subramanian H, Komorowski R, Whitaker M, Gorski J, Drobyski WR) Blood 2012 Jun 28;119(26):6354-64 21 Citations |
2 | Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension. (Kriska T, Cepura C, Magier D, Siangjong L, Gauthier KM, Campbell WB) Am J Physiol Heart Circ Physiol 2012 Jun 01;302(11):H2428-38 39 Citations |
1 | Peroxisome proliferator-activated receptor-γ protects against vascular aging. (Modrick ML, Kinzenbaw DA, Chu Y, Sigmund CD, Faraci FM) Am J Physiol Regul Integr Comp Physiol 2012 May 15;302(10):R1184-90 22 Citations |
1 | Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36. (Zhu W, Li W, Silverstein RL) Blood 2012 Jun 21;119(25):6136-44 83 Citations |
1 | Regulation of acute graft-versus-host disease by microRNA-155. (Ranganathan P, Heaphy CE, Costinean S, Stauffer N, Na C, Hamadani M, Santhanam R, Mao C, Taylor PA, Sandhu S, He G, Shana'ah A, Nuovo GJ, Lagana A, Cascione L, Obad S, Broom O, Kauppinen S, Byrd JC, Caligiuri M, Perrotti D, Hadley GA, Marcucci G, Devine SM, Blazar BR, Croce CM, Garzon R) Blood 2012 May 17;119(20):4786-97 123 Citations |
1 | Hippocampal histone acetylation regulates object recognition and the estradiol-induced enhancement of object recognition. (Zhao Z, Fan L, Fortress AM, Boulware MI, Frick KM) J Neurosci 2012 Feb 15;32(7):2344-51 101 Citations |
1 | Polycomb repressive complex 2 is required for MLL-AF9 leukemia. (Neff T, Sinha AU, Kluk MJ, Zhu N, Khattab MH, Stein L, Xie H, Orkin SH, Armstrong SA) Proc Natl Acad Sci U S A 2012 Mar 27;109(13):5028-33 181 Citations |
1 | Signaling through L-selectin mediates enhanced chemotaxis of lymphocyte subsets to secondary lymphoid tissue chemokine. (Subramanian H, Grailer JJ, Ohlrich KC, Rymaszewski AL, Loppnow JJ, Kodera M, Conway RM, Steeber DA) J Immunol 2012 Apr 01;188(7):3223-36 34 Citations |
2 | A novel IL-10-independent regulatory role for B cells in suppressing autoimmunity by maintenance of regulatory T cells via GITR ligand. (Ray A, Basu S, Williams CB, Salzman NH, Dittel BN) J Immunol 2012 Apr 01;188(7):3188-98 221 Citations |
2 | High-throughput detection method for influenza virus. (Kumar P, Bartoszek AE, Moran TM, Gorski J, Bhattacharyya S, Navidad JF, Thakar MS, Malarkannan S) J Vis Exp 2012 Feb 04(60) 11 Citations |
1 | B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. (Recher M, Burns SO, de la Fuente MA, Volpi S, Dahlberg C, Walter JE, Moffitt K, Mathew D, Honke N, Lang PA, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, Candotti F, Nadeau K, Bouma G, Delmonte OM, Frugoni F, Fomin AB, Buchbinder D, Lundequist EM, Massaad MJ, Tsokos GC, Hartwig J, Manis J, Terhorst C, Geha RS, Snapper S, Lang KS, Malley R, Westerberg L, Thrasher AJ, Notarangelo LD) Blood 2012 Mar 22;119(12):2819-28 90 Citations |
2 | Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by photobiomodulation induced by 670 nm light. (Muili KA, Gopalakrishnan S, Meyer SL, Eells JT, Lyons JA) PLoS One 2012;7(1):e30655 79 Citations |
1 | Potentiation of dietary restriction-induced lifespan extension by polyphenols. (Aires DJ, Rockwell G, Wang T, Frontera J, Wick J, Wang W, Tonkovic-Capin M, Lu J, E L, Zhu H, Swerdlow RH) Biochim Biophys Acta 2012 Apr;1822(4):522-6 19 Citations |
1 | Discovery of 2-(2-benzoxazoyl amino)-4-aryl-5-cyanopyrimidine as negative allosteric modulators (NAMs) of metabotropic glutamate receptor 5 (mGlu₅): from an artificial neural network virtual screen to an in vivo tool compound. (Mueller R, Dawson ES, Meiler J, Rodriguez AL, Chauder BA, Bates BS, Felts AS, Lamb JP, Menon UN, Jadhav SB, Kane AS, Jones CK, Gregory KJ, Niswender CM, Conn PJ, Olsen CM, Winder DG, Emmitte KA, Lindsley CW) ChemMedChem 2012 Mar 05;7(3):406-14 38 Citations |
1 | The progesterone-induced enhancement of object recognition memory consolidation involves activation of the extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin (mTOR) pathways in the dorsal hippocampus. (Orr PT, Rubin AJ, Fan L, Kent BA, Frick KM) Horm Behav 2012 Apr;61(4):487-95 36 Citations |
1 | Stimulus dynamics increase the self-administration of compound visual and auditory stimuli. (Olsen CM, Winder DG) Neurosci Lett 2012 Mar 05;511(1):8-11 17 Citations |
2 | Intravascular recovery of VWF and FVIII following intraperitoneal injection and differences from intravenous and subcutaneous injection in mice. (Shi Q, Kuether EL, Schroeder JA, Fahs SA, Montgomery RR) Haemophilia 2012 Jul;18(4):639-46 19 Citations |
2 | A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. (Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, Sinnamon AJ, Neubig RR, Newman DK, Stalker TJ, Brass LF) Blood 2012 Feb 23;119(8):1935-45 50 Citations |
2 | Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. (Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC) J Clin Invest 2012 Jan;122(1):178-91 240 Citations |
1 | Thrombomodulin is required for the antithrombotic activity of thrombin mutant W215A/E217A in a mouse model of arterial thrombosis. (Vicente CP, Weiler H, Di Cera E, Tollefsen DM) Thromb Res 2012 Oct;130(4):646-8 10 Citations |
1 | Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration. (Charbel Issa P, Singh MS, Lipinski DM, Chong NV, Delori FC, Barnard AR, MacLaren RE) Invest Ophthalmol Vis Sci 2012 Feb;53(2):1066-75 55 Citations |
1 | A mouse model of lamellar intrastromal femtosecond laser keratotomy: ultra-structural, inflammatory, and wound healing responses. (Angunawela RI, Poh R, Chaurasia SS, Tan DT, Mehta JS) Mol Vis 2011;17:3005-12 10 Citations |
2 | Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy. (Mukhopadhyay P, Horváth B, Zsengellér Z, Zielonka J, Tanchian G, Holovac E, Kechrid M, Patel V, Stillman IE, Parikh SM, Joseph J, Kalyanaraman B, Pacher P) Free Radic Biol Med 2012 Jan 15;52(2):497-506 176 Citations |
3 | PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking. (Privratsky JR, Tilkens SB, Newman DK, Newman PJ) Life Sci 2012 Jan 30;90(5-6):177-84 14 Citations |
1 | The hexosamine biosynthetic pathway and O-GlcNAcylation drive the expression of β-catenin and cell proliferation. (Olivier-Van Stichelen S, Guinez C, Mir AM, Perez-Cervera Y, Liu C, Michalski JC, Lefebvre T) Am J Physiol Endocrinol Metab 2012 Feb 15;302(4):E417-24 56 Citations |
2 | Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice. (Jansen AJ, Josefsson EC, Rumjantseva V, Liu QP, Falet H, Bergmeier W, Cifuni SM, Sackstein R, von Andrian UH, Wagner DD, Hartwig JH, Hoffmeister KM) Blood 2012 Feb 02;119(5):1263-73 158 Citations |
1 | Granzyme B regulates antiviral CD8+ T cell responses. (Salti SM, Hammelev EM, Grewal JL, Reddy ST, Zemple SJ, Grossman WJ, Grayson MH, Verbsky JW) J Immunol 2011 Dec 15;187(12):6301-9 59 Citations |
1 | TRPC1 contributes to light-touch sensation and mechanical responses in low-threshold cutaneous sensory neurons. (Garrison SR, Dietrich A, Stucky CL) J Neurophysiol 2012 Feb;107(3):913-22 69 Citations |
1 | Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype. (Pierson CR, Dulin-Smith AN, Durban AN, Marshall ML, Marshall JT, Snyder AD, Naiyer N, Gladman JT, Chandler DS, Lawlor MW, Buj-Bello A, Dowling JJ, Beggs AH) Hum Mol Genet 2012 Feb 15;21(4):811-25 47 Citations |
2 | Correction of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy. (Kanaji S, Kuether EL, Fahs SA, Schroeder JA, Ware J, Montgomery RR, Shi Q) Mol Ther 2012 Mar;20(3):625-32 30 Citations |
1 | Effects of experimental asthma on inflammation and lung mechanics in sickle cell mice. (Pritchard KA Jr, Feroah TR, Nandedkar SD, Holzhauer SL, Hutchins W, Schulte ML, Strunk RC, Debaun MR, Hillery CA) Am J Respir Cell Mol Biol 2012 Mar;46(3):389-96 24 Citations |
1 | NAD(P)H oxidase and eNOS play differential roles in cytomegalovirus infection-induced microvascular dysfunction. (Leskov IL, Whitsett J, Vasquez-Vivar J, Stokes KY) Free Radic Biol Med 2011 Dec 15;51(12):2300-8 13 Citations |
2 | Dynamic association of gammaherpesvirus DNA with core histone during de novo lytic infection of primary cells. (Mounce BC, Tsan FC, Kohler S, Cirillo LA, Tarakanova VL) Virology 2011 Dec 20;421(2):167-72 14 Citations |
1 | Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. (Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M) Mol Carcinog 2012 Dec;51(12):993-1002 20 Citations |
1 | Ccr5 regulates inflammatory gene expression in response to encephalomyocarditis virus infection. (Christmann BS, Moran JM, McGraw JA, Buller RM, Corbett JA) Am J Pathol 2011 Dec;179(6):2941-51 12 Citations |
1 | An in vivo rodent model of contraction-induced injury in the quadriceps muscle. (Pratt SJP, Lawlor MW, Shah SB, Lovering RM) Injury 2012 Jun;43(6):788-93 20 Citations |
1 | Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. (Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD) PLoS Genet 2011 Oct;7(10):e1002323 61 Citations |
1 | FGF23 induces left ventricular hypertrophy. (Faul C, Amaral AP, Oskouei B, Hu MC, Sloan A, Isakova T, Gutiérrez OM, Aguillon-Prada R, Lincoln J, Hare JM, Mundel P, Morales A, Scialla J, Fischer M, Soliman EZ, Chen J, Go AS, Rosas SE, Nessel L, Townsend RR, Feldman HI, St John Sutton M, Ojo A, Gadegbeku C, Di Marco GS, Reuter S, Kentrup D, Tiemann K, Brand M, Hill JA, Moe OW, Kuro-O M, Kusek JW, Keane MG, Wolf M) J Clin Invest 2011 Nov;121(11):4393-408 1623 Citations |
1 | Pulmonary hypertension in the newborn GTP cyclohydrolase I-deficient mouse. (Belik J, McIntyre BA, Enomoto M, Pan J, Grasemann H, Vasquez-Vivar J) Free Radic Biol Med 2011 Dec 15;51(12):2227-33 19 Citations |
2 | Dysfunctional HDL containing L159R ApoA-I leads to exacerbation of atherosclerosis in hyperlipidemic mice. (Sorci-Thomas MG, Zabalawi M, Bharadwaj MS, Wilhelm AJ, Owen JS, Asztalos BF, Bhat S, Thomas MJ) Biochim Biophys Acta 2012 Mar;1821(3):502-12 16 Citations |
2 | Gammaherpesvirus gene expression and DNA synthesis are facilitated by viral protein kinase and histone variant H2AX. (Mounce BC, Tsan FC, Droit L, Kohler S, Reitsma JM, Cirillo LA, Tarakanova VL) Virology 2011 Nov 25;420(2):73-81 18 Citations |
1 | Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice. (Pan B, Wang W, Zhong P, Blankman JL, Cravatt BF, Liu QS) J Neurosci 2011 Sep 21;31(38):13420-30 129 Citations |
1 | Antitumor activity of the investigational proteasome inhibitor MLN9708 in mouse models of B-cell and plasma cell malignancies. (Lee EC, Fitzgerald M, Bannerman B, Donelan J, Bano K, Terkelsen J, Bradley DP, Subakan O, Silva MD, Liu R, Pickard M, Li Z, Tayber O, Li P, Hales P, Carsillo M, Neppalli VT, Berger AJ, Kupperman E, Manfredi M, Bolen JB, Van Ness B, Janz S) Clin Cancer Res 2011 Dec 01;17(23):7313-23 94 Citations |
1 | Primary vascularization of the graft determines the immunodominance of murine minor H antigens during organ transplantation. (Kwun J, Malarkannan S, Burlingham WJ, Knechtle SJ) J Immunol 2011 Oct 15;187(8):3997-4006 15 Citations |
1 | Assessment of cone survival in response to CNTF, GDNF, and VEGF165b in a novel ex vivo model of end-stage retinitis pigmentosa. (Lipinski DM, Singh MS, MacLaren RE) Invest Ophthalmol Vis Sci 2011 Sep 21;52(10):7340-6 27 Citations |
1 | Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice. (Yu Y, Wang D, Liu C, Kaosaard K, Semple K, Anasetti C, Yu XZ) Blood 2011 Nov 03;118(18):5011-20 132 Citations |
1 | Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain. (Horowitz NA, Blevins EA, Miller WM, Perry AR, Talmage KE, Mullins ES, Flick MJ, Queiroz KC, Shi K, Spek CA, Conway EM, Monia BP, Weiler H, Degen JL, Palumbo JS) Blood 2011 Sep 08;118(10):2889-95 72 Citations |
1 | Constitutive androstane receptor activation decreases plasma apolipoprotein B-containing lipoproteins and atherosclerosis in low-density lipoprotein receptor-deficient mice. (Sberna AL, Assem M, Xiao R, Ayers S, Gautier T, Guiu B, Deckert V, Chevriaux A, Grober J, Le Guern N, Pais de Barros JP, Moore DD, Lagrost L, Masson D) Arterioscler Thromb Vasc Biol 2011 Oct;31(10):2232-9 30 Citations |
1 | Gelsolin-independent podosome formation in dendritic cells. (Hammarfjord O, Falet H, Gurniak C, Hartwig JH, Wallin RP) PLoS One 2011;6(7):e21615 10 Citations |
1 | CD103 deficiency prevents graft-versus-host disease but spares graft-versus-tumor effects mediated by alloreactive CD8 T cells. (Liu K, Anthony BA, Yearsly MM, Hamadani M, Gaughan A, Wang JJ, Devine SM, Hadley GA) PLoS One 2011;6(7):e21968 10 Citations |
3 | Recruitment of prefrontal cortical endocannabinoid signaling by glucocorticoids contributes to termination of the stress response. (Hill MN, McLaughlin RJ, Pan B, Fitzgerald ML, Roberts CJ, Lee TT, Karatsoreos IN, Mackie K, Viau V, Pickel VM, McEwen BS, Liu QS, Gorzalka BB, Hillard CJ) J Neurosci 2011 Jul 20;31(29):10506-15 286 Citations |
2 | Renal proximal tubule angiotensin AT1A receptors regulate blood pressure. (Li H, Weatherford ET, Davis DR, Keen HL, Grobe JL, Daugherty A, Cassis LA, Allen AM, Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2011 Oct;301(4):R1067-77 73 Citations |
1 | Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice. (Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH) J Pharmacol Exp Ther 2011 Oct;339(1):173-85 94 Citations |
1 | Differential expression of MMP-2 and -9 and their inhibitors in fetal lung cells exposed to mechanical stretch: regulation by IL-10. (Hawwa RL, Hokenson MA, Wang Y, Huang Z, Sharma S, Sanchez-Esteban J) Lung 2011 Aug;189(4):341-9 16 Citations |
1 | PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells. (Adapala RK, Talasila PK, Bratz IN, Zhang DX, Suzuki M, Meszaros JG, Thodeti CK) Am J Physiol Heart Circ Physiol 2011 Sep;301(3):H757-65 80 Citations |
1 | Characterization of a dominant cone degeneration in a green fluorescent protein-reporter mouse with disruption of Loci associated with human dominant retinal dystrophy. (Lipinski DM, Yusuf M, Barnard AR, Damant C, Charbel Issa P, Singh MS, Lee E, Davies WL, Volpi EV, MacLaren RE) Invest Ophthalmol Vis Sci 2011 Aug 22;52(9):6617-23 11 Citations |
2 | A role for the low-affinity A2B adenosine receptor in regulating superoxide generation by murine neutrophils. (van der Hoeven D, Wan TC, Gizewski ET, Kreckler LM, Maas JE, Van Orman J, Ravid K, Auchampach JA) J Pharmacol Exp Ther 2011 Sep;338(3):1004-12 45 Citations |
1 | Dopamine D₄ receptor activation controls circadian timing of the adenylyl cyclase 1/cyclic AMP signaling system in mouse retina. (Jackson CR, Chaurasia SS, Hwang CK, Iuvone PM) Eur J Neurosci 2011 Jul;34(1):57-64 62 Citations |
1 | Dual antigen target-based immunotherapy for prostate cancer eliminates the growth of established tumors in mice. (Karan D, Dubey S, Van Veldhuizen P, Holzbeierlein JM, Tawfik O, Thrasher JB) Immunotherapy 2011 Jun;3(6):735-46 20 Citations |
1 | Impaired sensory nerve function and axon morphology in mice with diabetic neuropathy. (Lennertz RC, Medler KA, Bain JL, Wright DE, Stucky CL) J Neurophysiol 2011 Aug;106(2):905-14 44 Citations |
2 | Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin αvβ₃. (Lakshmikanthan S, Sobczak M, Chun C, Henschel A, Dargatz J, Ramchandran R, Chrzanowska-Wodnicka M) Blood 2011 Aug 18;118(7):2015-26 92 Citations |
1 | Maternal antioxidant blocks programmed cardiovascular and behavioural stress responses in adult mice. (Roghair RD, Wemmie JA, Volk KA, Scholz TD, Lamb FS, Segar JL) Clin Sci (Lond) 2011 Nov;121(10):427-36 26 Citations |
1 | Angiotensin II-induced dilated cardiomyopathy in Balb/c but not C57BL/6J mice. (Peng H, Yang XP, Carretero OA, Nakagawa P, D'Ambrosio M, Leung P, Xu J, Peterson EL, González GE, Harding P, Rhaleb NE) Exp Physiol 2011 Aug;96(8):756-64 51 Citations |
1 | Effect of Thuja occidentalis and its polysaccharide on cell-mediated immune responses and cytokine levels of metastatic tumor-bearing animals. (Sunila ES, Hamsa TP, Kuttan G) Pharm Biol 2011 Oct;49(10):1065-73 28 Citations |
1 | Local long-term expression of lentivirally delivered IL-10 in the lung attenuates obliteration of intrapulmonary allograft airways. (Hirayama S, Sato M, Liu M, Loisel-Meyer S, Yeung JC, Wagnetz D, Cypel M, Zehong G, Medin JA, Keshavjee S) Hum Gene Ther 2011 Nov;22(11):1453-60 23 Citations |
1 | Instability of Foxp3 expression limits the ability of induced regulatory T cells to mitigate graft versus host disease. (Beres A, Komorowski R, Mihara M, Drobyski WR) Clin Cancer Res 2011 Jun 15;17(12):3969-83 79 Citations |
2 | Immunosuppressive effects of multiple myeloma are overcome by PD-L1 blockade. (Hallett WH, Jing W, Drobyski WR, Johnson BD) Biol Blood Marrow Transplant 2011 Aug;17(8):1133-45 137 Citations |
2 | Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression. (Potteaux S, Gautier EL, Hutchison SB, van Rooijen N, Rader DJ, Thomas MJ, Sorci-Thomas MG, Randolph GJ) J Clin Invest 2011 May;121(5):2025-36 283 Citations |
1 | The effect of hepatic ischemia reperfusion injury in a murine model of nonalcoholic steatohepatitis. (Tevar AD, Clarke CN, Schuster R, Wang J, Edwards MJ, Lentsch AB) J Surg Res 2011 Jul;169(1):e7-14 13 Citations |
1 | Roles of CD28, CTLA4, and inducible costimulator in acute graft-versus-host disease in mice. (Li J, Semple K, Suh WK, Liu C, Chen F, Blazar BR, Yu XZ) Biol Blood Marrow Transplant 2011 Jul;17(7):962-9 41 Citations |
1 | Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model. (Gehrking KM, Andresen JM, Duvick L, Lough J, Zoghbi HY, Orr HT) Hum Mol Genet 2011 Jun 01;20(11):2204-12 54 Citations |
1 | Vav guanine nucleotide exchange factors link hyperlipidemia and a prothrombotic state. (Chen K, Li W, Major J, Rahaman SO, Febbraio M, Silverstein RL) Blood 2011 May 26;117(21):5744-50 55 Citations |
1 | Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia. (Ge ZD, Ionova IA, Vladic N, Pravdic D, Hirata N, Vásquez-Vivar J, Pratt PF Jr, Warltier DC, Pieper GM, Kersten JR) Cardiovasc Res 2011 Jul 15;91(2):340-9 23 Citations |
1 | Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice. (Chen YG, Scheuplein F, Driver JP, Hewes AA, Reifsnyder PC, Leiter EH, Serreze DV) J Immunol 2011 Apr 01;186(7):4278-84 27 Citations |
1 | A novel tissue-engineered approach to problems of the postpneumonectomy space. (Tsunooka N, Hirayama S, Medin JA, Liles WC, Keshavjee S, Waddell TK) Ann Thorac Surg 2011 Mar;91(3):880-6 5 Citations |
2 | Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents. (Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE Jr, Park F) FASEB J 2011 Jun;25(6):1844-55 37 Citations |
1 | IL-10 inhibits inflammatory cytokines released by fetal mouse lung fibroblasts exposed to mechanical stretch. (Hawwa RL, Hokenson MA, Wang Y, Huang Z, Sharma S, Sanchez-Esteban J) Pediatr Pulmonol 2011 Jul;46(7):640-9 24 Citations |
1 | Nuclear export of the NF-κB inhibitor IκBα is required for proper B cell and secondary lymphoid tissue formation. (Wuerzberger-Davis SM, Chen Y, Yang DT, Kearns JD, Bates PW, Lynch C, Ladell NC, Yu M, Podd A, Zeng H, Huang TT, Wen R, Hoffmann A, Wang D, Miyamoto S) Immunity 2011 Feb 25;34(2):188-200 27 Citations |
1 | Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation. (Harlan SM, Morgan DA, Agassandian K, Guo DF, Cassell MD, Sigmund CD, Mark AL, Rahmouni K) Circ Res 2011 Apr 01;108(7):808-12 119 Citations |
1 | Plasmin plays an essential role in amplification of psoriasiform skin inflammation in mice. (Li Q, Ke F, Zhang W, Shen X, Xu Q, Wang H, Yu XZ, Leng Q, Wang H) PLoS One 2011 Feb 02;6(2):e16483 30 Citations |
3 | Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation. (Ming Z, Hu Y, Xiang J, Polewski P, Newman PJ, Newman DK) Blood 2011 Apr 07;117(14):3903-6 43 Citations |
1 | 1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis. (Mayne CG, Spanier JA, Relland LM, Williams CB, Hayes CE) Eur J Immunol 2011 Mar;41(3):822-32 139 Citations |
1 | Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice. (Lawlor MW, Read BP, Edelstein R, Yang N, Pierson CR, Stein MJ, Wermer-Colan A, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH) Am J Pathol 2011 Feb;178(2):784-93 52 Citations |
2 | Angiotensinergic signaling in the brain mediates metabolic effects of deoxycorticosterone (DOCA)-salt in C57 mice. (Grobe JL, Buehrer BA, Hilzendeger AM, Liu X, Davis DR, Xu D, Sigmund CD) Hypertension 2011 Mar;57(3):600-7 77 Citations |
1 | Tolerance induction by hematopoietic cell transplantation: combined use of stem cells and progenitor cells. (Domen J, Sun L, Trapp K, Maghami N, Inagaki E, Li Y, Simpson P, Gandy KL) J Heart Lung Transplant 2011 May;30(5):507-14 3 Citations |
1 | Alternate day fasting impacts the brain insulin-signaling pathway of young adult male C57BL/6 mice. (Lu J, E L, Wang W, Frontera J, Zhu H, Wang WT, Lee P, Choi IY, Brooks WM, Burns JM, Aires D, Swerdlow RH) J Neurochem 2011 Apr;117(1):154-63 15 Citations |
1 | Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteries. (Gauthier KM, Goldman DH, Aggarwal NT, Chawengsub Y, Falck JR, Campbell WB) Am J Physiol Heart Circ Physiol 2011 Mar;300(3):H725-35 32 Citations |
2 | Cell proliferation in the absence of E2F1-3. (Wenzel PL, Chong JL, Sáenz-Robles MT, Ferrey A, Hagan JP, Gomez YM, Rajmohan R, Sharma N, Chen HZ, Pipas JM, Robinson ML, Leone G) Dev Biol 2011 Mar 01;351(1):35-45 56 Citations |
1 | A functional family-wide screening of SP/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth. (Fernandez-Zapico ME, Lomberk GA, Tsuji S, DeMars CJ, Bardsley MR, Lin YH, Almada LL, Han JJ, Mukhopadhyay D, Ordog T, Buttar NS, Urrutia R) Biochem J 2011 Apr 15;435(2):529-37 83 Citations |
1 | Acamprosate reduces ethanol drinking behaviors and alters the metabolite profile in mice lacking ENT1. (Lee MR, Hinton DJ, Wu J, Mishra PK, Port JD, Macura SI, Choi DS) Neurosci Lett 2011 Feb 25;490(2):90-5 21 Citations |
4 | Abnormal fibrillin-1 expression and chronic oxidative stress mediate endothelial mesenchymal transition in a murine model of systemic sclerosis. (Xu H, Zaidi M, Struve J, Jones DW, Krolikowski JG, Nandedkar S, Lohr NL, Gadicherla A, Pagel PS, Csuka ME, Pritchard KA, Weihrauch D) Am J Physiol Cell Physiol 2011 Mar;300(3):C550-6 38 Citations |
1 | Operant sensation seeking requires metabotropic glutamate receptor 5 (mGluR5). (Olsen CM, Childs DS, Stanwood GD, Winder DG) PLoS One 2010 Nov 30;5(11):e15085 40 Citations |
1 | Constitutive androstane receptor activation stimulates faecal bile acid excretion and reverse cholesterol transport in mice. (Sberna AL, Assem M, Gautier T, Grober J, Guiu B, Jeannin A, Pais de Barros JP, Athias A, Lagrost L, Masson D) J Hepatol 2011 Jul;55(1):154-61 36 Citations |
2 | D-4F, an apoA-1 mimetic, decreases airway hyperresponsiveness, inflammation, and oxidative stress in a murine model of asthma. (Nandedkar SD, Weihrauch D, Xu H, Shi Y, Feroah T, Hutchins W, Rickaby DA, Duzgunes N, Hillery CA, Konduri KS, Pritchard KA Jr) J Lipid Res 2011 Mar;52(3):499-508 60 Citations |
1 | Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice. (Rajasekaran NS, Varadharaj S, Khanderao GD, Davidson CJ, Kannan S, Firpo MA, Zweier JL, Benjamin IJ) Antioxid Redox Signal 2011 Mar 15;14(6):957-71 111 Citations |
1 | Mesenchymal stem cells facilitate axon sorting, myelination, and functional recovery in paralyzed mice deficient in Schwann cell-derived laminin. (Carlson KB, Singh P, Feaster MM, Ramnarain A, Pavlides C, Chen ZL, Yu WM, Feltri ML, Strickland S) Glia 2011 Feb;59(2):267-77 47 Citations |
2 | Mesenchymal stromal cells are present in the heart and promote growth of adult stem cells in vitro. (Lushaj EB, Anstadt E, Haworth R, Roenneburg D, Kim J, Hematti P, Kohmoto T) Cytotherapy 2011 Apr;13(4):400-6 22 Citations |
1 | A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling. (Kennedy DJ, Kuchibhotla S, Westfall KM, Silverstein RL, Morton RE, Febbraio M) Cardiovasc Res 2011 Feb 15;89(3):604-13 145 Citations |
1 | P-selectin-mediated platelet-neutrophil aggregate formation activates neutrophils in mouse and human sickle cell disease. (Polanowska-Grabowska R, Wallace K, Field JJ, Chen L, Marshall MA, Figler R, Gear AR, Linden J) Arterioscler Thromb Vasc Biol 2010 Dec;30(12):2392-9 137 Citations |
1 | Increased ethanol consumption and preference in mice lacking neurotensin receptor type 2. (Lee MR, Hinton DJ, Unal SS, Richelson E, Choi DS) Alcohol Clin Exp Res 2011 Jan;35(1):99-107 28 Citations |
2 | The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance. (Grobe JL, Grobe CL, Beltz TG, Westphal SG, Morgan DA, Xu D, de Lange WJ, Li H, Sakai K, Thedens DR, Cassis LA, Rahmouni K, Mark AL, Johnson AK, Sigmund CD) Cell Metab 2010 Nov 03;12(5):431-42 125 Citations |
2 | Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes. (Duerr CU, Salzman NH, Dupont A, Szabo A, Normark BH, Normark S, Locksley RM, Mellroth P, Hornef MW) Mucosal Immunol 2011 May;4(3):325-34 24 Citations |
1 | Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation. (Atkinson C, He S, Morris K, Qiao F, Casey S, Goddard M, Tomlinson S) J Immunol 2010 Dec 01;185(11):7007-13 50 Citations |
1 | Mesenchymal stromal cells expressing ErbB-2/neu elicit protective antibreast tumor immunity in vivo, which is paradoxically suppressed by IFN-gamma and tumor necrosis factor-alpha priming. (Romieu-Mourez R, François M, Abate A, Boivin MN, Birman E, Bailey D, Bramson JL, Forner K, Young YK, Medin JA, Galipeau J) Cancer Res 2010 Oct 15;70(20):7742-7 16 Citations |
1 | Hypobaric hypoxia exacerbates the neuroinflammatory response to traumatic brain injury. (Goodman MD, Makley AT, Huber NL, Clarke CN, Friend LA, Schuster RM, Bailey SR, Barnes SL, Dorlac WC, Johannigman JA, Lentsch AB, Pritts TA) J Surg Res 2011 Jan;165(1):30-7 49 Citations |
2 | Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes. (Mathison A, Liebl A, Bharucha J, Mukhopadhyay D, Lomberk G, Shah V, Urrutia R) Pancreatology 2010;10(4):505-16 |
2 | Apolipoprotein A-I modulates regulatory T cells in autoimmune LDLr-/-, ApoA-I-/- mice. (Wilhelm AJ, Zabalawi M, Owen JS, Shah D, Grayson JM, Major AS, Bhat S, Gibbs DP Jr, Thomas MJ, Sorci-Thomas MG) J Biol Chem 2010 Nov 12;285(46):36158-69 107 Citations |
1 | Sequence variation at multiple loci influences red cell hemoglobin concentration. (Peters LL, Shavit JA, Lambert AJ, Tsaih SW, Li Q, Su Z, Leduc MS, Paigen B, Churchill GA, Ginsburg D, Brugnara C) Blood 2010 Dec 16;116(25):e139-49 10 Citations |
4 | Endothelial microparticles induce inflammation in acute lung injury. (Buesing KL, Densmore JC, Kaul S, Pritchard KA Jr, Jarzembowski JA, Gourlay DM, Oldham KT) J Surg Res 2011 Mar;166(1):32-9 75 Citations |
1 | Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ. (Chacko BK, Reily C, Srivastava A, Johnson MS, Ye Y, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V) Biochem J 2010 Nov 15;432(1):9-19 191 Citations |
2 | Evidence that the acute phase of ischemic preconditioning does not require signaling by the A 2B adenosine receptor. (Maas JE, Wan TC, Figler RA, Gross GJ, Auchampach JA) J Mol Cell Cardiol 2010 Nov;49(5):886-93 31 Citations |
1 | Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. (Schlosburg JE, Blankman JL, Long JZ, Nomura DK, Pan B, Kinsey SG, Nguyen PT, Ramesh D, Booker L, Burston JJ, Thomas EA, Selley DE, Sim-Selley LJ, Liu QS, Lichtman AH, Cravatt BF) Nat Neurosci 2010 Sep;13(9):1113-9 511 Citations |
2 | Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice. (Kerschen E, Hernandez I, Zogg M, Jia S, Hessner MJ, Fernandez JA, Griffin JH, Huettner CS, Castellino FJ, Weiler H) J Clin Invest 2010 Sep;120(9):3167-78 82 Citations |
1 | Portal vein ligation accelerates tumor growth in ligated, but not contralateral lobes. (Sakai N, Clarke CN, Schuster R, Blanchard J, Tevar AD, Edwards MJ, Lentsch AB) World J Gastroenterol 2010 Aug 14;16(30):3816-26 11 Citations |
2 | Effect of Borrelia burgdorferi OspC at the site of inoculation in mouse skin. (Antonara S, Ristow L, McCarthy J, Coburn J) Infect Immun 2010 Nov;78(11):4723-33 26 Citations |
1 | Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum. (Biswas A, Liu YJ, Hao L, Mizoguchi A, Salzman NH, Bevins CL, Kobayashi KS) Proc Natl Acad Sci U S A 2010 Aug 17;107(33):14739-44 139 Citations |
3 | Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress. (Wang W, Sun D, Pan B, Roberts CJ, Sun X, Hillard CJ, Liu QS) Neuropsychopharmacology 2010 Oct;35(11):2249-61 92 Citations |
1 | Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol. (Zhu X, Owen JS, Wilson MD, Li H, Griffiths GL, Thomas MJ, Hiltbold EM, Fessler MB, Parks JS) J Lipid Res 2010 Nov;51(11):3196-206 266 Citations |
1 | Diagnosis of partial body radiation exposure in mice using peripheral blood gene expression profiles. (Meadows SK, Dressman HK, Daher P, Himburg H, Russell JL, Doan P, Chao NJ, Lucas J, Nevins JR, Chute JP) PLoS One 2010 Jul 12;5(7):e11535 48 Citations |
1 | Early differential expression of oncostatin M in obstructive nephropathy. (Elbjeirami WM, Truong LD, Tawil A, Wang W, Dawson S, Lan HY, Zhang P, Garcia GE, Wayne Smith C) J Interferon Cytokine Res 2010 Jul;30(7):513-23 15 Citations |
1 | Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. (Bardsley MR, Horváth VJ, Asuzu DT, Lorincz A, Redelman D, Hayashi Y, Popko LN, Young DL, Lomberk GA, Urrutia RA, Farrugia G, Rubin BP, Ordog T) Gastroenterology 2010 Sep;139(3):942-52 98 Citations |
1 | Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. (Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A) Development 2010 Aug;137(16):2643-52 121 Citations |
1 | Involvement of noradrenergic neurotransmission in the stress- but not cocaine-induced reinstatement of extinguished cocaine-induced conditioned place preference in mice: role for β-2 adrenergic receptors. (Mantsch JR, Weyer A, Vranjkovic O, Beyer CE, Baker DA, Caretta H) Neuropsychopharmacology 2010 Oct;35(11):2165-78 102 Citations |
1 | Surviving lethal septic shock without fluid resuscitation in a rodent model. (Li Y, Liu B, Fukudome EY, Kochanek AR, Finkelstein RA, Chong W, Jin G, Lu J, deMoya MA, Velmahos GC, Alam HB) Surgery 2010 Aug;148(2):246-54 56 Citations |
1 | Conserved gammaherpesvirus kinase and histone variant H2AX facilitate gammaherpesvirus latency in vivo. (Tarakanova VL, Stanitsa E, Leonardo SM, Bigley TM, Gauld SB) Virology 2010 Sep 15;405(1):50-61 37 Citations |
1 | Rostrocaudal analysis of corpus callosum demyelination and axon damage across disease stages refines diffusion tensor imaging correlations with pathological features. (Xie M, Tobin JE, Budde MD, Chen CI, Trinkaus K, Cross AH, McDaniel DP, Song SK, Armstrong RC) J Neuropathol Exp Neurol 2010 Jul;69(7):704-16 135 Citations |
1 | Analyzing complex traits with congenic strains. (Shao H, Sinasac DS, Burrage LC, Hodges CA, Supelak PJ, Palmert MR, Moreno C, Cowley AW Jr, Jacob HJ, Nadeau JH) Mamm Genome 2010 Jun;21(5-6):276-86 41 Citations |
4 | Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. (Wang W, Xu H, Shi Y, Nandedkar S, Zhang H, Gao H, Feroah T, Weihrauch D, Schulte ML, Jones DW, Jarzembowski J, Sorci-Thomas M, Pritchard KA Jr) J Lipid Res 2010 Sep;51(9):2560-70 68 Citations |
1 | Thrombospondin-1 regulates the normal prostate in vivo through angiogenesis and TGF-beta activation. (Fitchev PP, Wcislak SM, Lee C, Bergh A, Brendler CB, Stellmach VM, Crawford SE, Mavroudis CD, Cornwell ML, Doll JA) Lab Invest 2010 Jul;90(7):1078-90 21 Citations |
2 | Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice. (Zhang G, Shi Q, Fahs SA, Kuether EL, Walsh CE, Montgomery RR) Blood 2010 Aug 26;116(8):1235-43 43 Citations |
2 | Cardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection. (Ionova IA, Vásquez-Vivar J, Cooley BC, Khanna AK, Whitsett J, Herrnreiter A, Migrino RQ, Ge ZD, Regner KR, Channon KM, Alp NJ, Pieper GM) Am J Physiol Heart Circ Physiol 2010 Jul;299(1):H88-96 8 Citations |
1 | Corneal myofibroblast generation from bone marrow-derived cells. (Barbosa FL, Chaurasia SS, Cutler A, Asosingh K, Kaur H, de Medeiros FW, Agrawal V, Wilson SE) Exp Eye Res 2010 Jul;91(1):92-6 92 Citations |
1 | Epidermal neural crest stem cell (EPI-NCSC)--mediated recovery of sensory function in a mouse model of spinal cord injury. (Hu YF, Gourab K, Wells C, Clewes O, Schmit BD, Sieber-Blum M) Stem Cell Rev Rep 2010 Jun;6(2):186-98 67 Citations |
2 | Integrin-independent role of CalDAG-GEFI in neutrophil chemotaxis. (Carbo C, Duerschmied D, Goerge T, Hattori H, Sakai J, Cifuni SM, White GC 2nd, Chrzanowska-Wodnicka M, Luo HR, Wagner DD) J Leukoc Biol 2010 Aug;88(2):313-9 28 Citations |
2 | TCR stimulation drives cleavage and shedding of the ITIM receptor CD31. (Fornasa G, Groyer E, Clement M, Dimitrov J, Compain C, Gaston AT, Varthaman A, Khallou-Laschet J, Newman DK, Graff-Dubois S, Nicoletti A, Caligiuri G) J Immunol 2010 May 15;184(10):5485-92 52 Citations |
1 | Toll-like receptor-4 mediates intestinal barrier breakdown after thermal injury. (Peterson CY, Costantini TW, Loomis WH, Putnam JG, Wolf P, Bansal V, Eliceiri BP, Baird A, Coimbra R) Surg Infect (Larchmt) 2010 Apr;11(2):137-44 43 Citations |
1 | Phosphatidylinositol 3-kinase regulates macrophage responses to double-stranded RNA and encephalomyocarditis virus. (Freudenburg W, Moran JM, Lents NH, Baldassare JJ, Buller RM, Corbett JA) J Innate Immun 2010;2(1):77-86 12 Citations |
1 | Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure. (Redding KM, Chen BL, Singh A, Re RN, Navar LG, Seth DM, Sigmund CD, Tang WW, Cook JL) Am J Physiol Heart Circ Physiol 2010 Jun;298(6):H1807-18 39 Citations |
1 | Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis. (Zhang L, Ren X, Alt E, Bai X, Huang S, Xu Z, Lynch PM, Moyer MP, Wen XF, Wu X) Nature 2010 Apr 15;464(7291):1058-61 124 Citations |
1 | Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool. (Lennertz RC, Tsunozaki M, Bautista DM, Stucky CL) J Neurosci 2010 Mar 24;30(12):4353-61 73 Citations |
1 | Estradiol-induced object memory consolidation in middle-aged female mice requires dorsal hippocampal extracellular signal-regulated kinase and phosphatidylinositol 3-kinase activation. (Fan L, Zhao Z, Orr PT, Chambers CH, Lewis MC, Frick KM) J Neurosci 2010 Mar 24;30(12):4390-400 129 Citations |
1 | Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells. (Himburg HA, Muramoto GG, Daher P, Meadows SK, Russell JL, Doan P, Chi JT, Salter AB, Lento WE, Reya T, Chao NJ, Chute JP) Nat Med 2010 Apr;16(4):475-82 232 Citations |
1 | Epigenetic alterations regulate estradiol-induced enhancement of memory consolidation. (Zhao Z, Fan L, Frick KM) Proc Natl Acad Sci U S A 2010 Mar 23;107(12):5605-10 181 Citations |
1 | VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans. (Fujikawa K, Iwata T, Inoue K, Akahori M, Kadotani H, Fukaya M, Watanabe M, Chang Q, Barnett EM, Swat W) PLoS One 2010 Feb 04;5(2):e9050 47 Citations |
2 | A(3) adenosine receptor activation during reperfusion reduces infarct size through actions on bone marrow-derived cells. (Ge ZD, van der Hoeven D, Maas JE, Wan TC, Auchampach JA) J Mol Cell Cardiol 2010 Aug;49(2):280-6 42 Citations |
1 | Neurotensin receptor type 1 regulates ethanol intoxication and consumption in mice. (Lee MR, Hinton DJ, Song JY, Lee KW, Choo C, Johng H, Unal SS, Richelson E, Choi DS) Pharmacol Biochem Behav 2010 Apr;95(2):235-41 30 Citations |
1 | Cholecystokinin knockout mice are resistant to high-fat diet-induced obesity. (Lo CM, King A, Samuelson LC, Kindel TL, Rider T, Jandacek RJ, Raybould HE, Woods SC, Tso P) Gastroenterology 2010 May;138(5):1997-2005 55 Citations |
1 | Altered glutamatergic neurotransmission in the striatum regulates ethanol sensitivity and intake in mice lacking ENT1. (Chen J, Nam HW, Lee MR, Hinton DJ, Choi S, Kim T, Kawamura T, Janak PH, Choi DS) Behav Brain Res 2010 Apr 02;208(2):636-42 52 Citations |
1 | Acid sphingomyelinase deficiency does not protect from graft-versus-host disease in transplant recipients with Niemann-Pick disease. (Tolar J, Eapen M, Orchard PJ, Blazar BR) Blood 2010 Jan 14;115(2):434-5 3 Citations |
1 | Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. (Muramoto GG, Russell JL, Safi R, Salter AB, Himburg HA, Daher P, Meadows SK, Doan P, Storms RW, Chao NJ, McDonnell DP, Chute JP) Stem Cells 2010 Mar 31;28(3):523-34 58 Citations |
1 | Ectopic T-cell specificity and absence of perforin and granzyme B alleviate neural damage in oligodendrocyte mutant mice. (Kroner A, Ip CW, Thalhammer J, Nave KA, Martini R) Am J Pathol 2010 Feb;176(2):549-55 22 Citations |
2 | Bioinformatic analysis of gene sets regulated by ligand-activated and dominant-negative peroxisome proliferator-activated receptor gamma in mouse aorta. (Keen HL, Halabi CM, Beyer AM, de Lange WJ, Liu X, Maeda N, Faraci FM, Casavant TL, Sigmund CD) Arterioscler Thromb Vasc Biol 2010 Mar;30(3):518-25 23 Citations |
2 | Spinal nerve ligation in mouse upregulates TRPV1 heat function in injured IB4-positive nociceptors. (Vilceanu D, Honore P, Hogan QH, Stucky CL) J Pain 2010 Jun;11(6):588-99 48 Citations |
1 | Diffusion tensor imaging at 3 hours after traumatic spinal cord injury predicts long-term locomotor recovery. (Kim JH, Loy DN, Wang Q, Budde MD, Schmidt RE, Trinkaus K, Song SK) J Neurotrauma 2010 Mar;27(3):587-98 103 Citations |
1 | Isoflurane postconditioning protects against reperfusion injury by preventing mitochondrial permeability transition by an endothelial nitric oxide synthase-dependent mechanism. (Ge ZD, Pravdic D, Bienengraeber M, Pratt PF Jr, Auchampach JA, Gross GJ, Kersten JR, Warltier DC) Anesthesiology 2010 Jan;112(1):73-85 78 Citations |
2 | Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice. (Beetz N, Harrison MD, Brede M, Zong X, Urbanski MJ, Sietmann A, Kaufling J, Lorkowski S, Barrot M, Seeliger MW, Vieira-Coelho MA, Hamet P, Gaudet D, Seda O, Tremblay J, Kotchen TA, Kaldunski M, Nüsing R, Szabo B, Jacob HJ, Cowley AW Jr, Biel M, Stoll M, Lohse MJ, Broeckel U, Hein L) J Clin Invest 2009 Dec;119(12):3597-3612 39 Citations |
1 | Cross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivo. (Ebrahem Q, Chaurasia SS, Vasanji A, Qi JH, Klenotic PA, Cutler A, Asosingh K, Erzurum S, Anand-Apte B) Am J Pathol 2010 Jan;176(1):496-503 97 Citations |
1 | Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension. (Feng Y, Xia H, Cai Y, Halabi CM, Becker LK, Santos RA, Speth RC, Sigmund CD, Lazartigues E) Circ Res 2010 Feb 05;106(2):373-82 165 Citations |
1 | MHV68 complement regulatory protein facilitates MHV68 replication in primary macrophages in a complement independent manner. (Tarakanova VL, Molleston JM, Goodwin M, Virgin HW 4th) Virology 2010 Jan 20;396(2):323-8 11 Citations |
1 | Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette. (Driver JP, Scheuplein F, Chen YG, Grier AE, Wilson SB, Serreze DV) Diabetes 2010 Feb;59(2):423-32 24 Citations |
2 | Oxidants induce alternative splicing of alpha-synuclein: Implications for Parkinson's disease. (Kalivendi SV, Yedlapudi D, Hillard CJ, Kalyanaraman B) Free Radic Biol Med 2010 Feb 01;48(3):377-83 39 Citations |
2 | Preservation of intracellular renin expression is insufficient to compensate for genetic loss of secreted renin. (Xu D, Borges GR, Grobe JL, Pelham CJ, Yang B, Sigmund CD) Hypertension 2009 Dec;54(6):1240-7 33 Citations |
1 | Non-redundant roles of phosphoinositide 3-kinase isoforms alpha and beta in glycoprotein VI-induced platelet signaling and thrombus formation. (Gilio K, Munnix IC, Mangin P, Cosemans JM, Feijge MA, van der Meijden PE, Olieslagers S, Chrzanowska-Wodnicka MB, Lillian R, Schoenwaelder S, Koyasu S, Sage SO, Jackson SP, Heemskerk JW) J Biol Chem 2009 Dec 04;284(49):33750-62 110 Citations |
1 | Sequential intramolecular epitope spreading of humoral responses to human BPAG2 in a transgenic model. (Di Zenzo G, Calabresi V, Olasz EB, Zambruno G, Yancey KB) J Invest Dermatol 2010 Apr;130(4):1040-7 25 Citations |
1 | Facilitative glucose transporter 9 expression affects glucose sensing in pancreatic beta-cells. (Evans SA, Doblado M, Chi MM, Corbett JA, Moley KH) Endocrinology 2009 Dec;150(12):5302-10 45 Citations |
1 | The noninvasive, quantitative, in vivo assessment of adenoviral-mediated gene delivery in skin wound biomaterials. (Peterson CY, Shaterian A, Borboa AK, Gonzalez AM, Potenza BM, Coimbra R, Eliceiri BP, Baird A) Biomaterials 2009 Dec;30(35):6788-93 11 Citations |
1 | Evaluation of phospholipid and liposomal S-adenosyl methionine for the treatment of liver injury in a murine model. (Wagner EJ, Brown CS, Mather JR, Scholcoff C, Krugner-Higby L, Heath TD) J Pharm Sci 2010 Apr;99(4):1800-9 3 Citations |
2 | Interleukin 17 is not required for autoimmune-mediated pathologic damage during chronic graft-versus-host disease. (Chen X, Das R, Komorowski R, van Snick J, Uyttenhove C, Drobyski WR) Biol Blood Marrow Transplant 2010 Jan;16(1):123-8 15 Citations |
2 | Adenosine suppresses lipopolysaccharide-induced tumor necrosis factor-alpha production by murine macrophages through a protein kinase A- and exchange protein activated by cAMP-independent signaling pathway. (Kreckler LM, Gizewski E, Wan TC, Auchampach JA) J Pharmacol Exp Ther 2009 Dec;331(3):1051-61 37 Citations |
1 | The functional impairment of natural killer cells during influenza virus infection. (Guo H, Kumar P, Moran TM, Garcia-Sastre A, Zhou Y, Malarkannan S) Immunol Cell Biol 2009;87(8):579-89 60 Citations |
1 | Mice lacking mannose 6-phosphate uncovering enzyme activity have a milder phenotype than mice deficient for N-acetylglucosamine-1-phosphotransferase activity. (Boonen M, Vogel P, Platt KA, Dahms N, Kornfeld S) Mol Biol Cell 2009 Oct;20(20):4381-9 23 Citations |
2 | The role of NF-kappaB and Smad3 in TGF-beta-mediated Foxp3 expression. (Jana S, Jailwala P, Haribhai D, Waukau J, Glisic S, Grossman W, Mishra M, Wen R, Wang D, Williams CB, Ghosh S) Eur J Immunol 2009 Sep;39(9):2571-83 42 Citations |
1 | Hypercoagulability inhibits monocyte transendothelial migration through protease-activated receptor-1-, phospholipase-Cbeta-, phosphoinositide 3-kinase-, and nitric oxide-dependent signaling in monocytes and promotes plaque stability. (Seehaus S, Shahzad K, Kashif M, Vinnikov IA, Schiller M, Wang H, Madhusudhan T, Eckstein V, Bierhaus A, Bea F, Blessing E, Weiler H, Frommhold D, Nawroth PP, Isermann B) Circulation 2009 Sep 01;120(9):774-84 63 Citations |
2 | Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling. (Pan B, Wang W, Long JZ, Sun D, Hillard CJ, Cravatt BF, Liu QS) J Pharmacol Exp Ther 2009 Nov;331(2):591-7 137 Citations |
1 | Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway. (Halberg RB, Waggoner J, Rasmussen K, White A, Clipson L, Prunuske AJ, Bacher JW, Sullivan R, Washington MK, Pitot HC, Petrini JH, Albertson DG, Dove WF) Cancer Res 2009 Jul 15;69(14):5768-75 35 Citations |
1 | Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site. (Raife TJ, Cao W, Atkinson BS, Bedell B, Montgomery RR, Lentz SR, Johnson GF, Zheng XL) Blood 2009 Aug 20;114(8):1666-74 97 Citations |
1 | IL-1R signaling within the central nervous system regulates CXCL12 expression at the blood-brain barrier and disease severity during experimental autoimmune encephalomyelitis. (McCandless EE, Budde M, Lees JR, Dorsey D, Lyng E, Klein RS) J Immunol 2009 Jul 01;183(1):613-20 77 Citations |
1 | Role of sialic acid for platelet life span: exposure of beta-galactose results in the rapid clearance of platelets from the circulation by asialoglycoprotein receptor-expressing liver macrophages and hepatocytes. (Sørensen AL, Rumjantseva V, Nayeb-Hashemi S, Clausen H, Hartwig JH, Wandall HH, Hoffmeister KM) Blood 2009 Aug 20;114(8):1645-54 174 Citations |
3 | Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease. (Chen X, Das R, Komorowski R, Beres A, Hessner MJ, Mihara M, Drobyski WR) Blood 2009 Jul 23;114(4):891-900 247 Citations |
1 | The canonical NF-kappaB pathway is required for formation of luminal mammary neoplasias and is activated in the mammary progenitor population. (Pratt MA, Tibbo E, Robertson SJ, Jansson D, Hurst K, Perez-Iratxeta C, Lau R, Niu MY) Oncogene 2009 Jul 30;28(30):2710-22 71 Citations |
1 | Dorsal hippocampal progesterone infusions enhance object recognition in young female mice. (Orr PT, Lewis MC, Frick KM) Pharmacol Biochem Behav 2009 Aug;93(2):177-82 31 Citations |
1 | Discovery of potent and practical antiangiogenic agents inspired by cortistatin A. (Czakó B, Kürti L, Mammoto A, Ingber DE, Corey EJ) J Am Chem Soc 2009 Jul 01;131(25):9014-9 55 Citations |
1 | Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death. (Yu Y, Iclozan C, Yamazaki T, Yang X, Anasetti C, Dong C, Yu XZ) Blood 2009 Jul 30;114(5):1026-8 32 Citations |
1 | The enhanced hypercalcemic response to 20-epi-1,25-dihydroxyvitamin D3 results from a selective and prolonged induction of intestinal calcium-regulating genes. (Zella LA, Meyer MB, Nerenz RD, Pike JW) Endocrinology 2009 Aug;150(8):3448-56 25 Citations |
1 | Genetic influence on electrocardiogram time intervals and heart rate in aging mice. (Xing S, Tsaih SW, Yuan R, Svenson KL, Jorgenson LM, So M, Paigen BJ, Korstanje R) Am J Physiol Heart Circ Physiol 2009 Jun;296(6):H1907-13 45 Citations |
1 | Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging. (Modrick ML, Didion SP, Sigmund CD, Faraci FM) Am J Physiol Heart Circ Physiol 2009 Jun;296(6):H1914-9 90 Citations |
1 | TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis. (Drage MG, Pecora ND, Hise AG, Febbraio M, Silverstein RL, Golenbock DT, Boom WH, Harding CV) Cell Immunol 2009;258(1):29-37 129 Citations |
2 | Apolipoprotein A-I and its role in lymphocyte cholesterol homeostasis and autoimmunity. (Wilhelm AJ, Zabalawi M, Grayson JM, Weant AE, Major AS, Owen J, Bharadwaj M, Walzem R, Chan L, Oka K, Thomas MJ, Sorci-Thomas MG) Arterioscler Thromb Vasc Biol 2009 Jun;29(6):843-9 102 Citations |
1 | Potent induction of B- and T-cell immunity against human carcinoembryonic antigen-expressing tumors in human carcinoembryonic antigen transgenic mice mediated by direct lentivector injection. (Loisel-Meyer S, Felizardo T, Mariotti J, Mossoba ME, Foley JE, Kammerer R, Mizue N, Keefe R, McCart JA, Zimmermann W, Dropulic B, Fowler DH, Medin JA) Mol Cancer Ther 2009 Mar;8(3):692-702 18 Citations |
2 | A mechanosensitive transcriptional mechanism that controls angiogenesis. (Mammoto A, Connor KM, Mammoto T, Yung CW, Huh D, Aderman CM, Mostoslavsky G, Smith LE, Ingber DE) Nature 2009 Feb 26;457(7233):1103-8 435 Citations |
1 | Dose-dependent effects of post-training estradiol plus progesterone treatment on object memory consolidation and hippocampal extracellular signal-regulated kinase activation in young ovariectomized mice. (Harburger LL, Saadi A, Frick KM) Neuroscience 2009 Apr 21;160(1):6-12 48 Citations |
1 | The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages. (Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H) Eur J Immunol 2009 Mar;39(3):820-5 57 Citations |
1 | Essential roles of dopamine D4 receptors and the type 1 adenylyl cyclase in photic control of cyclic AMP in photoreceptor cells. (Jackson CR, Chaurasia SS, Zhou H, Haque R, Storm DR, Iuvone PM) J Neurochem 2009 Apr;109(1):148-57 49 Citations |
1 | Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expression. (Relland LM, Mishra MK, Haribhai D, Edwards B, Ziegelbauer J, Williams CB) J Immunol 2009 Feb 01;182(3):1341-50 25 Citations |
1 | p18Ink4c and p53 Act as tumor suppressors in cyclin D1-driven primitive neuroectodermal tumor. (Saab R, Rodriguez-Galindo C, Matmati K, Rehg JE, Baumer SH, Khoury JD, Billups C, Neale G, Helton KJ, Skapek SX) Cancer Res 2009 Jan 15;69(2):440-8 21 Citations |
1 | Operant sensation seeking engages similar neural substrates to operant drug seeking in C57 mice. (Olsen CM, Winder DG) Neuropsychopharmacology 2009 Jun;34(7):1685-94 93 Citations |
1 | Vascular nitric oxide and superoxide anion contribute to sex-specific programmed cardiovascular physiology in mice. (Roghair RD, Segar JL, Volk KA, Chapleau MW, Dallas LM, Sorenson AR, Scholz TD, Lamb FS) Am J Physiol Regul Integr Comp Physiol 2009 Mar;296(3):R651-62 41 Citations |
1 | Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality. (Niessen F, Furlan-Freguia C, Fernández JA, Mosnier LO, Castellino FJ, Weiler H, Rosen H, Griffin JH, Ruf W) Blood 2009 Mar 19;113(12):2859-66 72 Citations |
1 | Endothelial progenitor cell infusion induces hematopoietic stem cell reconstitution in vivo. (Salter AB, Meadows SK, Muramoto GG, Himburg H, Doan P, Daher P, Russell L, Chen B, Chao NJ, Chute JP) Blood 2009 Feb 26;113(9):2104-7 126 Citations |
1 | Vessel microport technique for applications in cerebrovascular research. (Chen L, Swartz KR, Toborek M) J Neurosci Res 2009 May 15;87(7):1718-27 33 Citations |
1 | Retrovirally transduced murine T lymphocytes expressing FasL mediate effective killing of prostate cancer cells. (Symes JC, Siatskas C, Fowler DH, Medin JA) Cancer Gene Ther 2009 May;16(5):439-52 7 Citations |
1 | MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries. (Tang PC, Qin L, Zielonka J, Zhou J, Matte-Martone C, Bergaya S, van Rooijen N, Shlomchik WD, Min W, Sessa WC, Pober JS, Tellides G) J Exp Med 2008 Dec 22;205(13):3159-71 58 Citations |
1 | Transient anti-CD40L co-stimulation blockade prevents immune responses against human bullous pemphigoid antigen 2: implications for gene therapy. (Lanschuetzer CM, Olasz EB, Lazarova Z, Yancey KB) J Invest Dermatol 2009 May;129(5):1203-7 13 Citations |
1 | Tacrolimus (FK506) causes disease aggravation in models for inherited peripheral myelinopathies. (Ip CW, Kroner A, Kohl B, Wessig C, Martini R) Neurobiol Dis 2009 Feb;33(2):207-12 7 Citations |
1 | [Spatial and temporal changes of palatal cell proliferation and cell apoptosis of retinoic acid induced mouse cleft palate in different embryonic stages]. (Wang R, Liu B, Wang B, Cong W, Xiao J) Hua Xi Kou Qiang Yi Xue Za Zhi 2008 Oct;26(5):546-9 2 Citations |
1 | The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathy. (Kroner A, Schwab N, Ip CW, Sommer C, Wessig C, Wiendl H, Martini R) Neurobiol Dis 2009 Jan;33(1):96-103 12 Citations |
1 | The effects of acute 17beta-estradiol treatment on gene expression in the young female mouse hippocampus. (Pechenino AS, Frick KM) Neurobiol Learn Mem 2009 Mar;91(3):315-22 32 Citations |
1 | Temporal and spatial expression of collagens during murine atrioventricular heart valve development and maintenance. (Peacock JD, Lu Y, Koch M, Kadler KE, Lincoln J) Dev Dyn 2008 Oct;237(10):3051-8 57 Citations |
1 | The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation. (Guo H, Samarakoon A, Vanhaesebroeck B, Malarkannan S) J Exp Med 2008 Sep 29;205(10):2419-35 90 Citations |
1 | In vivo delivery of human acid ceramidase via cord blood transplantation and direct injection of lentivirus as novel treatment approaches for Farber disease. (Ramsubir S, Nonaka T, Girbés CB, Carpentier S, Levade T, Medin JA) Mol Genet Metab 2008 Nov;95(3):133-41 29 Citations |
1 | Effects of sildenafil on nigrostriatal dopamine neurons in a murine model of Parkinson's disease. (Janis KL, Brennan RT, Drolet RE, Behrouz B, Kaufman SK, Lookingland KJ, Goudreau JL) J Alzheimers Dis 2008 Sep;15(1):97-107 5 Citations |
2 | Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in nonobese diabetic (NOD) mice. (Chen YG, Scheuplein F, Osborne MA, Tsaih SW, Chapman HD, Serreze DV) Diabetes 2008 Dec;57(12):3273-80 18 Citations |
1 | Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice. (Su Z, Wang X, Tsaih SW, Zhang A, Cox A, Sheehan S, Paigen B) J Lipid Res 2009 Jan;50(1):116-25 20 Citations |
1 | Estradiol-induced enhancement of object memory consolidation involves hippocampal extracellular signal-regulated kinase activation and membrane-bound estrogen receptors. (Fernandez SM, Lewis MC, Pechenino AS, Harburger LL, Orr PT, Gresack JE, Schafe GE, Frick KM) J Neurosci 2008 Aug 27;28(35):8660-7 237 Citations |
1 | CD28 controls differentiation of regulatory T cells from naive CD4 T cells. (Guo F, Iclozan C, Suh WK, Anasetti C, Yu XZ) J Immunol 2008 Aug 15;181(4):2285-91 94 Citations |
2 | Endothelium-specific interference with peroxisome proliferator activated receptor gamma causes cerebral vascular dysfunction in response to a high-fat diet. (Beyer AM, de Lange WJ, Halabi CM, Modrick ML, Keen HL, Faraci FM, Sigmund CD) Circ Res 2008 Sep 12;103(6):654-61 84 Citations |
2 | Site-specific effects of PECAM-1 on atherosclerosis in LDL receptor-deficient mice. (Goel R, Schrank BR, Arora S, Boylan B, Fleming B, Miura H, Newman PJ, Molthen RC, Newman DK) Arterioscler Thromb Vasc Biol 2008 Nov;28(11):1996-2002 89 Citations |
1 | Differential effects of acute progesterone administration on spatial and object memory in middle-aged and aged female C57BL/6 mice. (Lewis MC, Orr PT, Frick KM) Horm Behav 2008 Aug;54(3):455-62 38 Citations |
2 | Activation of the A(3) adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils. (van der Hoeven D, Wan TC, Auchampach JA) Mol Pharmacol 2008 Sep;74(3):685-96 70 Citations |
1 | Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease. (Agarwal A, Bumm TG, Corbin AS, O'Hare T, Loriaux M, VanDyke J, Willis SG, Deininger J, Nakayama KI, Druker BJ, Deininger MW) Blood 2008 Sep 01;112(5):1960-70 58 Citations |
1 | Origin of CD11b+ macrophage-like cells in the CNS of PLP-overexpressing mice: low influx of haematogenous macrophages and unchanged blood-brain-barrier in the optic nerve. (Ip CW, Kohl B, Kleinschnitz C, Reuss B, Nave KA, Kroner A, Martini R) Mol Cell Neurosci 2008 Aug;38(4):489-94 13 Citations |
1 | Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2. (Shi PP, Cao XR, Sweezer EM, Kinney TS, Williams NR, Husted RF, Nair R, Weiss RM, Williamson RA, Sigmund CD, Snyder PM, Staub O, Stokes JB, Yang B) Am J Physiol Renal Physiol 2008 Aug;295(2):F462-70 136 Citations |
1 | TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis. (Wang H, Peters T, Sindrilaru A, Kess D, Oreshkova T, Yu XZ, Seier AM, Schreiber H, Wlaschek M, Blakytny R, Röhrbein J, Schulz G, Weiss JM, Scharffetter-Kochanek K) J Clin Invest 2008 Jul;118(7):2629-39 57 Citations |
1 | Estradiol-induced enhancement of object memory consolidation involves NMDA receptors and protein kinase A in the dorsal hippocampus of female C57BL/6 mice. (Lewis MC, Kerr KM, Orr PT, Frick KM) Behav Neurosci 2008 Jun;122(3):716-21 96 Citations |
1 | Quantitative trait loci for urinary albumin in crosses between C57BL/6J and A/J inbred mice in the presence and absence of Apoe. (Doorenbos C, Tsaih SW, Sheehan S, Ishimori N, Navis G, Churchill G, Dipetrillo K, Korstanje R) Genetics 2008 May;179(1):693-9 15 Citations |
1 | Platelet CD36 mediates interactions with endothelial cell-derived microparticles and contributes to thrombosis in mice. (Ghosh A, Li W, Febbraio M, Espinola RG, McCrae KR, Cockrell E, Silverstein RL) J Clin Invest 2008 May;118(5):1934-43 143 Citations |
1 | B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. (Ortler S, Leder C, Mittelbronn M, Zozulya AL, Knolle PA, Chen L, Kroner A, Wiendl H) Eur J Immunol 2008 Jun;38(6):1734-44 63 Citations |
1 | Candidate genes for obesity revealed from a C57BL/6J x 129S1/SvImJ intercross. (Su Z, Korstanje R, Tsaih SW, Paigen B) Int J Obes (Lond) 2008 Jul;32(7):1180-9 27 Citations |
1 | Gene expression signatures of radiation response are specific, durable and accurate in mice and humans. (Meadows SK, Dressman HK, Muramoto GG, Himburg H, Salter A, Wei Z, Ginsburg GS, Chao NJ, Nevins JR, Chute JP) PLoS One 2008 Apr 02;3(4):e1912 97 Citations |
1 | Lipooligosaccharides containing phosphorylcholine delay pulmonary clearance of nontypeable Haemophilus influenzae. (Pang B, Winn D, Johnson R, Hong W, West-Barnette S, Kock N, Swords WE) Infect Immun 2008 May;76(5):2037-43 43 Citations |
1 | Topical interleukin-1 receptor antagonist inhibits inflammatory cell infiltration into the cornea. (Stapleton WM, Chaurasia SS, Medeiros FW, Mohan RR, Sinha S, Wilson SE) Exp Eye Res 2008 May;86(5):753-7 48 Citations |
1 | CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice. (Drover VA, Nguyen DV, Bastie CC, Darlington YF, Abumrad NA, Pessin JE, London E, Sahoo D, Phillips MC) J Biol Chem 2008 May 09;283(19):13108-15 121 Citations |
2 | Species and strain differences in rodent sciatic nerve anatomy: implications for studies of neuropathic pain. (Rigaud M, Gemes G, Barabas ME, Chernoff DI, Abram SE, Stucky CL, Hogan QH) Pain 2008 May;136(1-2):188-201 220 Citations |
2 | Interference with PPAR gamma function in smooth muscle causes vascular dysfunction and hypertension. (Halabi CM, Beyer AM, de Lange WJ, Keen HL, Baumbach GL, Faraci FM, Sigmund CD) Cell Metab 2008 Mar;7(3):215-26 145 Citations |
1 | Widespread hyperplasia induced by transgenic TGFalpha in ApcMin mice is associated with only regional effects on tumorigenesis. (Bilger A, Sullivan R, Prunuske AJ, Clipson L, Drinkwater NR, Dove WF) Carcinogenesis 2008 Sep;29(9):1825-30 7 Citations |
2 | Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. (Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, de Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM) Hypertension 2008 Apr;51(4):867-71 102 Citations |
1 | Use of a cryptic splice site for the expression of huntingtin interacting protein 1 in select normal and neoplastic tissues. (Graves CW, Philips ST, Bradley SV, Oravecz-Wilson KI, Li L, Gauvin A, Ross TS) Cancer Res 2008 Feb 15;68(4):1064-73 4 Citations |
1 | Primary naive and interleukin-2-activated natural killer cells do not support efficient ectromelia virus replication. (Parker AK, Yokoyama WM, Corbett JA, Chen N, Buller RML) J Gen Virol 2008 Mar;89(Pt 3):751-759 6 Citations |
2 | Direct evidence for epithelial-mesenchymal transitions in breast cancer. (Trimboli AJ, Fukino K, de Bruin A, Wei G, Shen L, Tanner SM, Creasap N, Rosol TJ, Robinson ML, Eng C, Ostrowski MC, Leone G) Cancer Res 2008 Feb 01;68(3):937-45 318 Citations |
1 | Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. (Zhou J, Febbraio M, Wada T, Zhai Y, Kuruba R, He J, Lee JH, Khadem S, Ren S, Li S, Silverstein RL, Xie W) Gastroenterology 2008 Feb;134(2):556-67 489 Citations |
1 | Tumor protection following vaccination with low doses of lentivirally transduced DCs expressing the self-antigen erbB2. (Mossoba ME, Walia JS, Rasaiah VI, Buxhoeveden N, Head R, Ying C, Foley JE, Bramson JL, Fowler DH, Medin JA) Mol Ther 2008 Mar;16(3):607-17 22 Citations |
1 | Effect of homeopathic medicines on transplanted tumors in mice. (Es S, Kuttan G, Kc P, Kuttan R) Asian Pac J Cancer Prev 2007;8(3):390-4 21 Citations |
1 | Galactosylation does not prevent the rapid clearance of long-term, 4 degrees C-stored platelets. (Wandall HH, Hoffmeister KM, Sørensen AL, Rumjantseva V, Clausen H, Hartwig JH, Slichter SJ) Blood 2008 Mar 15;111(6):3249-56 77 Citations |
1 | Axonal injury detected by in vivo diffusion tensor imaging correlates with neurological disability in a mouse model of multiple sclerosis. (Budde MD, Kim JH, Liang HF, Russell JH, Cross AH, Song SK) NMR Biomed 2008 Jul;21(6):589-97 159 Citations |
1 | AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements. (Kovalchuk AL, duBois W, Mushinski E, McNeil NE, Hirt C, Qi CF, Li Z, Janz S, Honjo T, Muramatsu M, Ried T, Behrens T, Potter M) J Exp Med 2007 Nov 26;204(12):2989-3001 42 Citations |
1 | Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis. (Isermann B, Vinnikov IA, Madhusudhan T, Herzog S, Kashif M, Blautzik J, Corat MA, Zeier M, Blessing E, Oh J, Gerlitz B, Berg DT, Grinnell BW, Chavakis T, Esmon CT, Weiler H, Bierhaus A, Nawroth PP) Nat Med 2007 Nov;13(11):1349-58 345 Citations |
1 | A heat shock protein 90 binding domain in endothelial nitric-oxide synthase influences enzyme function. (Xu H, Shi Y, Wang J, Jones D, Weilrauch D, Ying R, Wakim B, Pritchard KA Jr) J Biol Chem 2007 Dec 28;282(52):37567-74 56 Citations |
3 | The proinflammatory phenotype of PECAM-1-deficient mice results in atherogenic diet-induced steatohepatitis. (Goel R, Boylan B, Gruman L, Newman PJ, North PE, Newman DK) Am J Physiol Gastrointest Liver Physiol 2007 Dec;293(6):G1205-14 35 Citations |
1 | Microarray analysis reveals distinctive signaling between the bed nucleus of the stria terminalis, nucleus accumbens, and dorsal striatum. (Olsen CM, Huang Y, Goodwin S, Ciobanu DC, Lu L, Sutter TR, Winder DG) Physiol Genomics 2008 Feb 19;32(3):283-98 16 Citations |
3 | The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-3'-aminoadenosine-5'-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel. (Wan TC, Ge ZD, Tampo A, Mio Y, Bienengraeber MW, Tracey WR, Gross GJ, Kwok WM, Auchampach JA) J Pharmacol Exp Ther 2008 Jan;324(1):234-43 69 Citations |
2 | Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. (Kerschen EJ, Fernandez JA, Cooley BC, Yang XV, Sood R, Mosnier LO, Castellino FJ, Mackman N, Griffin JH, Weiler H) J Exp Med 2007 Oct 01;204(10):2439-48 263 Citations |
1 | Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice. (Leder C, Schwab N, Ip CW, Kroner A, Nave KA, Dornmair K, Martini R, Wiendl H) Mol Cell Neurosci 2007 Nov;36(3):416-24 17 Citations |
1 | Life-long environmental enrichment differentially affects the mnemonic response to estrogen in young, middle-aged, and aged female mice. (Gresack JE, Kerr KM, Frick KM) Neurobiol Learn Mem 2007 Nov;88(4):393-408 68 Citations |
1 | Genetic analysis of albuminuria in a cross between C57BL/6J and DBA/2J mice. (Sheehan S, Tsaih SW, King BL, Stanton C, Churchill GA, Paigen B, DiPetrillo K) Am J Physiol Renal Physiol 2007 Nov;293(5):F1649-56 36 Citations |
2 | Bcl10 plays a divergent role in NK cell-mediated cytotoxicity and cytokine generation. (Malarkannan S, Regunathan J, Chu H, Kutlesa S, Chen Y, Zeng H, Wen R, Wang D) J Immunol 2007 Sep 15;179(6):3752-62 37 Citations |
1 | Age-dependent effects of environmental enrichment on spatial reference memory in male mice. (Harburger LL, Lambert TJ, Frick KM) Behav Brain Res 2007 Dec 11;185(1):43-8 92 Citations |
1 | Prolonged colonization of mice by Vibrio cholerae El Tor O1 depends on accessory toxins. (Olivier V, Salzman NH, Satchell KJ) Infect Immun 2007 Oct;75(10):5043-51 68 Citations |
3 | Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease. (Chen X, Vodanovic-Jankovic S, Johnson B, Keller M, Komorowski R, Drobyski WR) Blood 2007 Nov 15;110(10):3804-13 204 Citations |
1 | Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man. (Luchtefeld M, Schunkert H, Stoll M, Selle T, Lorier R, Grote K, Sagebiel C, Jagavelu K, Tietge UJ, Assmus U, Streetz K, Hengstenberg C, Fischer M, Mayer B, Maresso K, El Mokhtari NE, Schreiber S, Müller W, Bavendiek U, Grothusen C, Drexler H, Trautwein C, Broeckel U, Schieffer B) J Exp Med 2007 Aug 06;204(8):1935-44 57 Citations |
1 | Single enrichment variables differentially reduce age-related memory decline in female mice. (Harburger LL, Nzerem CK, Frick KM) Behav Neurosci 2007 Aug;121(4):679-88 40 Citations |
1 | In vivo MRI volumetric measurement of prostate regression and growth in mice. (Nastiuk KL, Liu H, Hamamura M, Muftuler LT, Nalcioglu O, Krolewski JJ) BMC Urol 2007 Jul 24;7:12 21 Citations |
1 | Spectrum of heart disease associated with murine and human GATA4 mutation. (Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Benson DW, Smoot LB, Pu WT) J Mol Cell Cardiol 2007 Dec;43(6):677-85 205 Citations |
1 | Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models. (Xie X, Xia W, Li Z, Kuo HP, Liu Y, Li Z, Ding Q, Zhang S, Spohn B, Yang Y, Wei Y, Lang JY, Evans DB, Chiao PJ, Abbruzzese JL, Hung MC) Cancer Cell 2007 Jul;12(1):52-65 69 Citations |
1 | Rb-mediated neuronal differentiation through cell-cycle-independent regulation of E2f3a. (Chen D, Opavsky R, Pacal M, Tanimoto N, Wenzel P, Seeliger MW, Leone G, Bremner R) PLoS Biol 2007 Jul;5(7):e179 73 Citations |
1 | Phospholipase Cgamma2 contributes to light-chain gene activation and receptor editing. (Bai L, Chen Y, He Y, Dai X, Lin X, Wen R, Wang D) Mol Cell Biol 2007 Sep;27(17):5957-67 20 Citations |
1 | Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration. (Tan Z, Sun X, Hou FS, Oh HW, Hilgenberg LG, Hol EM, van Leeuwen FW, Smith MA, O'Dowd DK, Schreiber SS) Cell Death Differ 2007 Oct;14(10):1721-32 72 Citations |
1 | Paradoxical enhancement of CD8 T cell-dependent anti-tumor protection despite reduced CD8 T cell responses with addition of a TLR9 agonist to a tumor vaccine. (Karan D, Krieg AM, Lubaroff DM) Int J Cancer 2007 Oct 01;121(7):1520-8 41 Citations |
1 | Characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin D3 in mouse kidney and intestine in vivo. (Meyer MB, Zella LA, Nerenz RD, Pike JW) J Biol Chem 2007 Aug 03;282(31):22344-52 88 Citations |
1 | Cellular immune response to an engineered cell-based tumor vaccine at the vaccination site. (Zhou Q, Johnson BD, Orentas RJ) Cell Immunol 2007 Feb;245(2):91-102 5 Citations |
1 | The menthol receptor TRPM8 is the principal detector of environmental cold. (Bautista DM, Siemens J, Glazer JM, Tsuruda PR, Basbaum AI, Stucky CL, Jordt SE, Julius D) Nature 2007 Jul 12;448(7150):204-8 1033 Citations |
3 | Effects of D-4F on vasodilation, oxidative stress, angiostatin, myocardial inflammation, and angiogenic potential in tight-skin mice. (Weihrauch D, Xu H, Shi Y, Wang J, Brien J, Jones DW, Kaul S, Komorowski RA, Csuka ME, Oldham KT, Pritchard KA) Am J Physiol Heart Circ Physiol 2007 Sep;293(3):H1432-41 66 Citations |
1 | Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. (McClellan KA, Ruzhynsky VA, Douda DN, Vanderluit JL, Ferguson KL, Chen D, Bremner R, Park DS, Leone G, Slack RS) Mol Cell Biol 2007 Jul;27(13):4825-43 71 Citations |
1 | Postmortem delay does not change regional diffusion anisotropy characteristics in mouse spinal cord white matter. (Kim JH, Trinkaus K, Ozcan A, Budde MD, Song SK) NMR Biomed 2007 May;20(3):352-9 32 Citations |
2 | Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers. (Sood R, Zogg M, Westrick RJ, Guo YH, Kerschen EJ, Girardi G, Salmon JE, Coughlin SR, Weiler H) J Exp Med 2007 May 14;204(5):1049-56 36 Citations |
1 | Selective reconstitution of liver cholesterol biosynthesis promotes lung maturation but does not prevent neonatal lethality in Dhcr7 null mice. (Yu H, Li M, Tint GS, Chen J, Xu G, Patel SB) BMC Dev Biol 2007 Apr 04;7:27 10 Citations |
1 | Toward accurate diagnosis of white matter pathology using diffusion tensor imaging. (Budde MD, Kim JH, Liang HF, Schmidt RE, Russell JH, Cross AH, Song SK) Magn Reson Med 2007 Apr;57(4):688-95 337 Citations |
1 | Anti-CD25 targeted killing of bicistronically transduced cells: a novel safety mechanism against retroviral genotoxicity. (Ramsubir S, Yoshimitsu M, Medin JA) Mol Ther 2007 Jun;15(6):1174-81 8 Citations |
1 | Visualization of degenerating axons in a dysmyelinating mouse mutant with axonal loss. (Ey B, Kobsar I, Blazyca H, Kroner A, Martini R) Mol Cell Neurosci 2007 May;35(1):153-60 20 Citations |
1 | Modulation of angiogenesis by dithiolethione-modified NSAIDs and valproic acid. (Isenberg JS, Jia Y, Field L, Ridnour LA, Sparatore A, Del Soldato P, Sowers AL, Yeh GC, Moody TW, Wink DA, Ramchandran R, Roberts DD) Br J Pharmacol 2007 May;151(1):63-72 73 Citations |
1 | Distinct regional and subcellular localization of adenylyl cyclases type 1 and 8 in mouse brain. (Conti AC, Maas JW Jr, Muglia LM, Dave BA, Vogt SK, Tran TT, Rayhel EJ, Muglia LJ) Neuroscience 2007 May 11;146(2):713-29 69 Citations |
1 | Humanization of autoantigen. (Nishie W, Sawamura D, Goto M, Ito K, Shibaki A, McMillan JR, Sakai K, Nakamura H, Olasz E, Yancey KB, Akiyama M, Shimizu H) Nat Med 2007 Mar;13(3):378-83 251 Citations |
1 | Induction of natural killer cell responses by ectromelia virus controls infection. (Parker AK, Parker S, Yokoyama WM, Corbett JA, Buller RM) J Virol 2007 Apr;81(8):4070-9 92 Citations |
1 | Regulatory T cell development in the absence of functional Foxp3. (Lin W, Haribhai D, Relland LM, Truong N, Carlson MR, Williams CB, Chatila TA) Nat Immunol 2007 Apr;8(4):359-68 399 Citations |
1 | Mouse model of oral infection with virulent type A Francisella tularensis. (KuoLee R, Zhao X, Austin J, Harris G, Conlan JW, Chen W) Infect Immun 2007 Apr;75(4):1651-60 28 Citations |
2 | Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets. (Rathore VB, Okada M, Newman PJ, Newman DK) Biochem J 2007 Apr 15;403(2):275-81 24 Citations |
1 | Loss of apolipoprotein E exacerbates the neonatal lethality of the Smith-Lemli-Opitz syndrome mouse. (Solcà C, Pandit B, Yu H, Tint GS, Patel SB) Mol Genet Metab 2007 May;91(1):7-14 10 Citations |
1 | Involvement of MAPKs in endostatin-mediated regulation of blood-retinal barrier function. (Campbell M, Collery R, McEvoy A, Gardiner TA, Stitt AW, Brankin B) Curr Eye Res 2006 Dec;31(12):1033-45 29 Citations |
1 | Short report: Association of macrophage inflammatory response and cell death after in vitro Borrelia burgdorferi infection with arthritis resistance. (Glickstein LJ, Coburn JL) Am J Trop Med Hyg 2006 Nov;75(5):964-7 14 Citations |
1 | ADME transcriptome in Hispanic versus White donor livers: evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics. (Finkelstein D, Lamba V, Assem M, Rengelshausen J, Yasuda K, Strom S, Schuetz E) Xenobiotica 2006;36(10-11):989-1012 12 Citations |
1 | Gammadelta T cells do not require fully functional cytotoxic pathways or the ability to recognize recipient alloantigens to prevent graft rejection. (Vodanovic-Jankovic S, Drobyski WR) Biol Blood Marrow Transplant 2006 Nov;12(11):1125-34 6 Citations |
1 | Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression. (Serreze DV, Osborne MA, Chen YG, Chapman HD, Pearson T, Brehm MA, Greiner DL) J Immunol 2006 Nov 15;177(10):6675-84 23 Citations |
1 | Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus. (McCray PB Jr, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia HP, Halabi C, Sigmund CD, Meyerholz DK, Kirby P, Look DC, Perlman S) J Virol 2007 Jan;81(2):813-21 698 Citations |
1 | Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice. (Ip CW, Kroner A, Crocker PR, Nave KA, Martini R) Neurobiol Dis 2007 Jan;25(1):105-11 49 Citations |
1 | Correction of cardiac abnormalities in fabry mice by direct intraventricular injection of a recombinant lentiviral vector that engineers expression of alpha-galactosidase A. (Yoshimitsu M, Higuchi K, Dawood F, Rasaiah VI, Ayach B, Chen M, Liu P, Medin JA) Circ J 2006 Nov;70(11):1503-8 29 Citations |
1 | Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response. (Sinnayah P, Lazartigues E, Sakai K, Sharma RV, Sigmund CD, Davisson RL) Circ Res 2006 Nov 10;99(10):1125-31 40 Citations |
2 | Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury. (Densmore JC, Signorino PR, Ou J, Hatoum OA, Rowe JJ, Shi Y, Kaul S, Jones DW, Sabina RE, Pritchard KA Jr, Guice KS, Oldham KT) Shock 2006 Nov;26(5):464-71 148 Citations |
1 | Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis. (Wen R, Chen Y, Bai L, Fu G, Schuman J, Dai X, Zeng H, Yang C, Stephan RP, Cleveland JL, Wang D) Mol Cell Biol 2006 Dec;26(24):9364-76 29 Citations |
1 | Differentiated dopaminergic MN9D cells only partially recapitulate the electrophysiological properties of midbrain dopaminergic neurons. (Rick CE, Ebert A, Virag T, Bohn MC, Surmeier DJ) Dev Neurosci 2006;28(6):528-37 25 Citations |
3 | Improved cardiac function in infarcted mice after treatment with pluripotent embryonic stem cells. (Nelson TJ, Ge ZD, Van Orman J, Barron M, Rudy-Reil D, Hacker TA, Misra R, Duncan SA, Auchampach JA, Lough JW) Anat Rec A Discov Mol Cell Evol Biol 2006 Nov;288(11):1216-24 55 Citations |
1 | Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations. (Dorrance AM, Liu S, Yuan W, Becknell B, Arnoczky KJ, Guimond M, Strout MP, Feng L, Nakamura T, Yu L, Rush LJ, Weinstein M, Leone G, Wu L, Ferketich A, Whitman SP, Marcucci G, Caligiuri MA) J Clin Invest 2006 Oct;116(10):2707-16 105 Citations |
1 | Complex genetic architecture revealed by analysis of high-density lipoprotein cholesterol in chromosome substitution strains and F2 crosses. (Stylianou IM, Tsaih SW, DiPetrillo K, Ishimori N, Li R, Paigen B, Churchill G) Genetics 2006 Oct;174(2):999-1007 28 Citations |
1 | Effects of continuous and intermittent estrogen treatments on memory in aging female mice. (Gresack JE, Frick KM) Brain Res 2006 Oct 18;1115(1):135-47 52 Citations |
1 | Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes. (Ip CW, Kroner A, Bendszus M, Leder C, Kobsar I, Fischer S, Wiendl H, Nave KA, Martini R) J Neurosci 2006 Aug 02;26(31):8206-16 100 Citations |
1 | Microarray analysis of differentially expressed genes in mouse bone marrow tissues after ionizing radiation. (Dai JM, Sun DC, Lin RX, Yang J, Lou S, Wang SQ) Int J Radiat Biol 2006 Jul;82(7):511-21 19 Citations |
1 | Sample-specific diamagnetic and paramagnetic passive shimming. (Koch KM, Brown PB, Rothman DL, de Graaf RA) J Magn Reson 2006 Sep;182(1):66-74 47 Citations |
1 | Identification of a TLR-independent pathway for Borrelia burgdorferi-induced expression of matrix metalloproteinases and inflammatory mediators through binding to integrin alpha 3 beta 1. (Behera AK, Hildebrand E, Uematsu S, Akira S, Coburn J, Hu LT) J Immunol 2006 Jul 01;177(1):657-64 58 Citations |
1 | A method for single-session cocaine self-administration in the mouse. (Olsen CM, Winder DG) Psychopharmacology (Berl) 2006 Jul;187(1):13-21 11 Citations |
1 | Post-training estrogen enhances spatial and object memory consolidation in female mice. (Gresack JE, Frick KM) Pharmacol Biochem Behav 2006 May;84(1):112-9 126 Citations |
1 | Opposing effects of ICOS on graft-versus-host disease mediated by CD4 and CD8 T cells. (Yu XZ, Liang Y, Nurieva RI, Guo F, Anasetti C, Dong C) J Immunol 2006 Jun 15;176(12):7394-401 43 Citations |
1 | T-cell tolerance or function is determined by combinatorial costimulatory signals. (Nurieva R, Thomas S, Nguyen T, Martin-Orozco N, Wang Y, Kaja MK, Yu XZ, Dong C) EMBO J 2006 Jun 07;25(11):2623-33 201 Citations |
1 | Functional expression of mouse relaxin and mouse relaxin-3 in the lung from an Ebola virus glycoprotein-pseudotyped lentivirus via tracheal delivery. (Silvertown JD, Walia JS, Summerlee AJ, Medin JA) Endocrinology 2006 Aug;147(8):3797-808 24 Citations |
1 | Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. (Zhou C, Assem M, Tay JC, Watkins PB, Blumberg B, Schuetz EG, Thummel KE) J Clin Invest 2006 Jun;116(6):1703-12 218 Citations |
2 | Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression. (Carrier EJ, Auchampach JA, Hillard CJ) Proc Natl Acad Sci U S A 2006 May 16;103(20):7895-900 374 Citations |
1 | Lymphoblastic leukemia/lymphoma in mice overexpressing the Mer (MerTK) receptor tyrosine kinase. (Keating AK, Salzberg DB, Sather S, Liang X, Nickoloff S, Anwar A, Deryckere D, Hill K, Joung D, Sawczyn KK, Park J, Curran-Everett D, McGavran L, Meltesen L, Gore L, Johnson GL, Graham DK) Oncogene 2006 Oct 05;25(45):6092-100 81 Citations |
1 | Angiotensinogen modulates renal vasculature growth. (Brand M, Lamandé N, Sigmund CD, Larger E, Corvol P, Gasc JM) Hypertension 2006 Jun;47(6):1067-74 14 Citations |
1 | Effects of estrogen and progesterone on spatial memory consolidation in aged females. (Harburger LL, Bennett JC, Frick KM) Neurobiol Aging 2007 Apr;28(4):602-10 81 Citations |
1 | Mice heterozygous for beta-ENaC deletion have defective potassium excretion. (Cao XR, Shi PP, Sigmund RD, Husted RF, Sigmund CD, Williamson RA, Stokes JB, Yang B) Am J Physiol Renal Physiol 2006 Jul;291(1):F107-15 13 Citations |
1 | Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration. (Grueter BA, Gosnell HB, Olsen CM, Schramm-Sapyta NL, Nekrasova T, Landreth GE, Winder DG) J Neurosci 2006 Mar 22;26(12):3210-9 99 Citations |
1 | Piper longum inhibits VEGF and proinflammatory cytokines and tumor-induced angiogenesis in C57BL/6 mice. (Sunila ES, Kuttan G) Int Immunopharmacol 2006 May;6(5):733-41 35 Citations |
1 | Upregulation of immunoproteasomes by nitric oxide: potential antioxidative mechanism in endothelial cells. (Kotamraju S, Matalon S, Matsunaga T, Shang T, Hickman-Davis JM, Kalyanaraman B) Free Radic Biol Med 2006 Mar 15;40(6):1034-44 87 Citations |
1 | RAS blockade decreases blood pressure and proteinuria in transgenic mice overexpressing rat angiotensinogen gene in the kidney. (Sachetelli S, Liu Q, Zhang SL, Liu F, Hsieh TJ, Brezniceanu ML, Guo DF, Filep JG, Ingelfinger JR, Sigmund CD, Hamet P, Chan JS) Kidney Int 2006 Mar;69(6):1016-23 111 Citations |
1 | Nonalcoholic Fatty gallbladder disease: the influence of diet in lean and obese mice. (Goldblatt MI, Swartz-Basile DA, Al-Azzawi HH, Tran KQ, Nakeeb A, Pitt HA) J Gastrointest Surg 2006 Feb;10(2):193-201 23 Citations |
1 | Sleeping Beauty-mediated transposition and long-term expression in vivo: use of the LoxP/Cre recombinase system to distinguish transposition-specific expression. (Score PR, Belur LR, Frandsen JL, Geurts JL, Yamaguchi T, Somia NV, Hackett PB, Largaespada DA, McIvor RS) Mol Ther 2006 Mar;13(3):617-24 27 Citations |
2 | Adenosine inhibits tumor necrosis factor-alpha release from mouse peritoneal macrophages via A2A and A2B but not the A3 adenosine receptor. (Kreckler LM, Wan TC, Ge ZD, Auchampach JA) J Pharmacol Exp Ther 2006 Apr;317(1):172-80 168 Citations |
1 | Detecting axon damage in spinal cord from a mouse model of multiple sclerosis. (Kim JH, Budde MD, Liang HF, Klein RS, Russell JH, Cross AH, Song SK) Neurobiol Dis 2006 Mar;21(3):626-32 209 Citations |
1 | A murine model of deep vein thrombosis: characterization and validation in transgenic mice. (Cooley BC, Szema L, Chen CY, Schwab JP, Schmeling G) Thromb Haemost 2005 Sep;94(3):498-503 38 Citations |
1 | Long-term continuous, but not daily, environmental enrichment reduces spatial memory decline in aged male mice. (Bennett JC, McRae PA, Levy LJ, Frick KM) Neurobiol Learn Mem 2006 Mar;85(2):139-52 149 Citations |
1 | Transgenic expression of a dominant-negative ASIC3 subunit leads to increased sensitivity to mechanical and inflammatory stimuli. (Mogil JS, Breese NM, Witty MF, Ritchie J, Rainville ML, Ase A, Abbadi N, Stucky CL, Séguéla P) J Neurosci 2005 Oct 26;25(43):9893-901 110 Citations |
3 | Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. (Ou J, Wang J, Xu H, Ou Z, Sorci-Thomas MG, Jones DW, Signorino P, Densmore JC, Kaul S, Oldham KT, Pritchard KA Jr) Circ Res 2005 Nov 25;97(11):1190-7 111 Citations |
1 | Cocaine self-administration reduces excitatory responses in the mouse nucleus accumbens shell. (Schramm-Sapyta NL, Olsen CM, Winder DG) Neuropsychopharmacology 2006 Jul;31(7):1444-51 47 Citations |
3 | Platelet PECAM-1 inhibits thrombus formation in vivo. (Falati S, Patil S, Gross PL, Stapleton M, Merrill-Skoloff G, Barrett NE, Pixton KL, Weiler H, Cooley B, Newman DK, Newman PJ, Furie BC, Furie B, Gibbins JM) Blood 2006 Jan 15;107(2):535-41 177 Citations |
1 | Neuroblastoma cells transiently transfected to simultaneously express the co-stimulatory molecules CD54, CD80, CD86, and CD137L generate antitumor immunity in mice. (Johnson BD, Gershan JA, Natalia N, Zujewski H, Weber JJ, Yan X, Orentas RJ) J Immunother 2005;28(5):449-60 32 Citations |
1 | Cerebral vascular effects of angiotensin II: new insights from genetic models. (Faraci FM, Lamping KG, Modrick ML, Ryan MJ, Sigmund CD, Didion SP) J Cereb Blood Flow Metab 2006 Apr;26(4):449-55 85 Citations |
1 | Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli. (Maresz K, Carrier EJ, Ponomarev ED, Hillard CJ, Dittel BN) J Neurochem 2005 Oct;95(2):437-45 406 Citations |
1 | Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation. (Albert MH, Liu Y, Anasetti C, Yu XZ) Eur J Immunol 2005 Sep;35(9):2598-607 75 Citations |
1 | Encephalomyocarditis virus induces PKR-independent mitogen-activated protein kinase activation in macrophages. (Moran JM, Moxley MA, Buller RM, Corbett JA) J Virol 2005 Aug;79(16):10226-36 22 Citations |
1 | Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver. (Duranski MR, Greer JJ, Dejam A, Jaganmohan S, Hogg N, Langston W, Patel RP, Yet SF, Wang X, Kevil CG, Gladwin MT, Lefer DJ) J Clin Invest 2005 May;115(5):1232-40 585 Citations |
1 | CD36 deficiency impairs intestinal lipid secretion and clearance of chylomicrons from the blood. (Drover VA, Ajmal M, Nassir F, Davidson NO, Nauli AM, Sahoo D, Tso P, Abumrad NA) J Clin Invest 2005 May;115(5):1290-7 199 Citations |
1 | Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse. (Breese NM, George AC, Pauers LE, Stucky CL) Pain 2005 May;115(1-2):37-49 128 Citations |
1 | A human single-chain Fv intrabody preferentially targets amino-terminal Huntingtin's fragments in striatal models of Huntington's disease. (Miller TW, Zhou C, Gines S, MacDonald ME, Mazarakis ND, Bates GP, Huston JS, Messer A) Neurobiol Dis 2005;19(1-2):47-56 51 Citations |
1 | Different types of environmental enrichment have discrepant effects on spatial memory and synaptophysin levels in female mice. (Lambert TJ, Fernandez SM, Frick KM) Neurobiol Learn Mem 2005 May;83(3):206-16 156 Citations |
1 | The class B scavenger receptor CD36 mediates free radical production and tissue injury in cerebral ischemia. (Cho S, Park EM, Febbraio M, Anrather J, Park L, Racchumi G, Silverstein RL, Iadecola C) J Neurosci 2005 Mar 09;25(10):2504-12 184 Citations |
1 | The antiangiogenic effect of thrombospondin-2 is mediated by CD36 and modulated by histidine-rich glycoprotein. (Simantov R, Febbraio M, Silverstein RL) Matrix Biol 2005 Feb;24(1):27-34 91 Citations |
1 | Calcium-stimulated adenylyl cyclases modulate ethanol-induced neurodegeneration in the neonatal brain. (Maas JW Jr, Indacochea RA, Muglia LM, Tran TT, Vogt SK, West T, Benz A, Shute AA, Holtzman DM, Mennerick S, Olney JW, Muglia LJ) J Neurosci 2005 Mar 02;25(9):2376-85 38 Citations |
1 | Emergent autoimmunity in graft-versus-host disease. (Tivol E, Komorowski R, Drobyski WR) Blood 2005 Jun 15;105(12):4885-91 109 Citations |
1 | Borrelia burgdorferi, an extracellular pathogen, circumvents osteopontin in inducing an inflammatory cytokine response. (Craig-Mylius K, Weber GF, Coburn J, Glickstein L) J Leukoc Biol 2005 May;77(5):710-8 12 Citations |
2 | Rap1b is required for normal platelet function and hemostasis in mice. (Chrzanowska-Wodnicka M, Smyth SS, Schoenwaelder SM, Fischer TH, White GC 2nd) J Clin Invest 2005 Mar;115(3):680-7 268 Citations |
1 | Chronic oral estrogen affects memory and neurochemistry in middle-aged female mice. (Fernandez SM, Frick KM) Behav Neurosci 2004 Dec;118(6):1340-51 78 Citations |
1 | The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feedback control of p38. (Zhao Q, Shepherd EG, Manson ME, Nelin LD, Sorokin A, Liu Y) J Biol Chem 2005 Mar 04;280(9):8101-8 193 Citations |
2 | Quiescent neural cells regain multipotent stem cell characteristics influenced by adult neural stem cells in co-culture. (Alexanian AR, Kurpad SN) Exp Neurol 2005 Jan;191(1):193-7 21 Citations |
1 | Regulation and function of trefoil factor family 3 expression in the biliary tree. (Nozaki I, Lunz JG 3rd, Specht S, Park JI, Giraud AS, Murase N, Demetris AJ) Am J Pathol 2004 Dec;165(6):1907-20 45 Citations |
1 | The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity. (Patel S, Carrier EJ, Ho WS, Rademacher DJ, Cunningham S, Reddy DS, Falck JR, Cravatt BF, Hillard CJ) J Lipid Res 2005 Feb;46(2):342-9 115 Citations |
1 | Leptin-resistant obese mice do not form biliary crystals on a high cholesterol diet. (Graewin SJ, Lee KH, Tran KQ, Goldblatt MI, Svatek CL, Nakeeb A, Pitt HA) J Surg Res 2004 Dec;122(2):145-9 10 Citations |
1 | Stem cell transplantation reveals that absence of macrophage CD36 is protective against atherosclerosis. (Febbraio M, Guy E, Silverstein RL) Arterioscler Thromb Vasc Biol 2004 Dec;24(12):2333-8 152 Citations |
1 | Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance? (Rosenblum MD, Olasz EB, Yancey KB, Woodliff JE, Lazarova Z, Gerber KA, Truitt RL) J Invest Dermatol 2004 Nov;123(5):880-7 98 Citations |
1 | A NotI-EcoRV promoter library for studies of genetic and epigenetic alterations in mouse models of human malignancies. (Yu L, Liu C, Bennett K, Wu YZ, Dai Z, Vandeusen J, Opavsky R, Raval A, Trikha P, Rodriguez B, Becknell B, Mao C, Lee S, Davuluri RV, Leone G, Van den Veyver IB, Caligiuri MA, Plass C) Genomics 2004 Oct;84(4):647-60 22 Citations |
1 | Prevention of lethal acute GVHD with an agonistic CD28 antibody and rapamycin. (Albert MH, Yu XZ, Martin PJ, Anasetti C) Blood 2005 Feb 01;105(3):1355-61 20 Citations |
1 | Structure of cerebral arterioles in mice deficient in expression of the gene for endothelial nitric oxide synthase. (Baumbach GL, Sigmund CD, Faraci FM) Circ Res 2004 Oct 15;95(8):822-9 61 Citations |
1 | Environmental enrichment reduces the mnemonic and neural benefits of estrogen. (Gresack JE, Frick KM) Neuroscience 2004;128(3):459-71 70 Citations |
3 | Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration. (Gendelman M, Halligan N, Komorowski R, Logan B, Murphy WJ, Blazar BR, Pritchard KA Jr, Drobyski WR) Blood 2005 Jan 01;105(1):428-31 10 Citations |
1 | Role of fibrinogen- and platelet-mediated hemostasis in mouse embryogenesis and reproduction. (Palumbo JS, Zogg M, Talmage KE, Degen JL, Weiler H, Isermann BH) J Thromb Haemost 2004 Aug;2(8):1368-79 35 Citations |
1 | Characterization of Lef-1 promoter segments that facilitate inductive developmental expression in skin. (Liu X, Driskell RR, Luo M, Abbott D, Filali M, Cheng N, Sigmund CD, Engelhardt JF) J Invest Dermatol 2004 Aug;123(2):264-74 29 Citations |
1 | Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice. (Cheung WC, Kim JS, Linden M, Peng L, Van Ness B, Polakiewicz RD, Janz S) J Clin Invest 2004 Jun;113(12):1763-73 95 Citations |
2 | Traumatic brain injury increases TGF beta RII expression on endothelial cells. (Fee DB, Sewell DL, Andresen K, Jacques TJ, Piaskowski S, Barger BA, Hart MN, Fabry Z) Brain Res 2004 Jun 25;1012(1-2):52-9 27 Citations |
1 | Selenium deficiency abrogates inflammation-dependent plasma cell tumors in mice. (Felix K, Gerstmeier S, Kyriakopoulos A, Howard OM, Dong HF, Eckhaus M, Behne D, Bornkamm GW, Janz S) Cancer Res 2004 Apr 15;64(8):2910-7 31 Citations |
1 | The P2Y agonist UTP activates cutaneous afferent fibers. (Stucky CL, Medler KA, Molliver DC) Pain 2004 May;109(1-2):36-44 64 Citations |
1 | Elevated presence of retrotransposons at sites of DNA double strand break repair in mouse models of metabolic oxidative stress and MYC-induced lymphoma. (Rockwood LD, Felix K, Janz S) Mutat Res 2004 Apr 14;548(1-2):117-25 21 Citations |
1 | Gene expression profiling of potential PPARgamma target genes in mouse aorta. (Keen HL, Ryan MJ, Beyer A, Mathur S, Scheetz TE, Gackle BD, Faraci FM, Casavant TL, Sigmund CD) Physiol Genomics 2004 Jun 17;18(1):33-42 44 Citations |
1 | A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. (Klett EL, Lu K, Kosters A, Vink E, Lee MH, Altenburg M, Shefer S, Batta AK, Yu H, Chen J, Klein R, Looije N, Oude-Elferink R, Groen AK, Maeda N, Salen G, Patel SB) BMC Med 2004 Mar 24;2:5 125 Citations |
1 | Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice. (Ryan MJ, Didion SP, Mathur S, Faraci FM, Sigmund CD) Hypertension 2004 May;43(5):1074-9 72 Citations |
1 | Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. (Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD) J Biol Chem 2004 May 21;279(21):22250-7 217 Citations |
1 | Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior. (Wemmie JA, Coryell MW, Askwith CC, Lamani E, Leonard AS, Sigmund CD, Welsh MJ) Proc Natl Acad Sci U S A 2004 Mar 09;101(10):3621-6 173 Citations |
1 | Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease. (Gendelman M, Hecht T, Logan B, Vodanovic-Jankovic S, Komorowski R, Drobyski WR) J Immunol 2004 Mar 01;172(5):3328-36 31 Citations |
1 | Adipose depot-specific modulation of angiotensinogen gene expression in diet-induced obesity. (Rahmouni K, Mark AL, Haynes WG, Sigmund CD) Am J Physiol Endocrinol Metab 2004 Jun;286(6):E891-5 97 Citations |
1 | Lck is required for activation-induced T cell death after TCR ligation with partial agonists. (Yu XZ, Levin SD, Madrenas J, Anasetti C) J Immunol 2004 Feb 01;172(3):1437-43 17 Citations |
1 | CD36 mediates the phagocytosis of Plasmodium falciparum-infected erythrocytes by rodent macrophages. (Patel SN, Serghides L, Smith TG, Febbraio M, Silverstein RL, Kurtz TW, Pravenec M, Kain KC) J Infect Dis 2004 Jan 15;189(2):204-13 108 Citations |
1 | BCL2 accelerates inflammation-induced BALB/c plasmacytomas and promotes novel tumors with coexisting T(12;15) and T(6;15) translocations. (Silva S, Kovalchuk AL, Kim JS, Klein G, Janz S) Cancer Res 2003 Dec 15;63(24):8656-63 26 Citations |
1 | Sex differences in the behavioral response to spatial and object novelty in adult C57BL/6 mice. (Frick KM, Gresack JE) Behav Neurosci 2003 Dec;117(6):1283-91 171 Citations |
1 | Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1. (Sluka KA, Price MP, Breese NM, Stucky CL, Wemmie JA, Welsh MJ) Pain 2003 Dec;106(3):229-239 381 Citations |
2 | CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance. (Rosenblum MD, Olasz E, Woodliff JE, Johnson BD, Konkol MC, Gerber KA, Orentas RJ, Sandford G, Truitt RL) Blood 2004 Apr 01;103(7):2691-8 68 Citations |
1 | Abnormal coronary function in mice deficient in alpha1H T-type Ca2+ channels. (Chen CC, Lamping KG, Nuno DW, Barresi R, Prouty SJ, Lavoie JL, Cribbs LL, England SK, Sigmund CD, Weiss RM, Williamson RA, Hill JA, Campbell KP) Science 2003 Nov 21;302(5649):1416-8 305 Citations |
1 | Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. (Nanba D, Mammoto A, Hashimoto K, Higashiyama S) J Cell Biol 2003 Nov 10;163(3):489-502 139 Citations |
1 | Heat shock protein 90 and tyrosine kinase regulate eNOS NO* generation but not NO* bioactivity. (Ou J, Fontana JT, Ou Z, Jones DW, Ackerman AW, Oldham KT, Yu J, Sessa WC, Pritchard KA Jr) Am J Physiol Heart Circ Physiol 2004 Feb;286(2):H561-9 52 Citations |
1 | Hypoxia-induced acute lung injury in murine models of sickle cell disease. (Pritchard KA Jr, Ou J, Ou Z, Shi Y, Franciosi JP, Signorino P, Kaul S, Ackland-Berglund C, Witte K, Holzhauer S, Mohandas N, Guice KS, Oldham KT, Hillery CA) Am J Physiol Lung Cell Mol Physiol 2004 Apr;286(4):L705-14 68 Citations |
1 | Glycosylation restores survival of chilled blood platelets. (Hoffmeister KM, Josefsson EC, Isaac NA, Clausen H, Hartwig JH, Stossel TP) Science 2003 Sep 12;301(5639):1531-4 235 Citations |
1 | Mouse kidney expresses mRNA of four highly related sodium-glucose cotransporters: regulation by cadmium. (Tabatabai NM, Blumenthal SS, Lewand DL, Petering DH) Kidney Int 2003 Oct;64(4):1320-30 26 Citations |
1 | Paradoxical decrease in mutant frequencies and chromosomal rearrangements in a transgenic lacZ reporter gene in Ku80 null mice deficient in DNA double strand break repair. (Rockwood LD, Nussenzweig A, Janz S) Mutat Res 2003 Aug 28;529(1-2):51-8 15 Citations |
1 | Male mice exhibit better spatial working and reference memory than females in a water-escape radial arm maze task. (Gresack JE, Frick KM) Brain Res 2003 Aug 22;982(1):98-107 67 Citations |
1 | Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells. (Xue L, Morris SW, Orihuela C, Tuomanen E, Cui X, Wen R, Wang D) Nat Immunol 2003 Sep;4(9):857-65 160 Citations |
1 | Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets. (Bergmeier W, Burger PC, Piffath CL, Hoffmeister KM, Hartwig JH, Nieswandt B, Wagner DD) Blood 2003 Dec 01;102(12):4229-35 148 Citations |
1 | Identification of T-cell epitopes in clotting factor IX and lack of tolerance in inbred mice. (Greenwood R, Wang B, Midkiff K, White GC 2nd, Lin HF, Frelinger JA) J Thromb Haemost 2003 Jan;1(1):95-102 16 Citations |
1 | Congenital lack of COX-2 affects mechanical and geometric properties of bone in mice. (Chen Q, Rho JY, Fan Z, Laulederkind SJ, Raghow R) Calcif Tissue Int 2003 Oct;73(4):387-92 34 Citations |
1 | Gene transfer establishes primacy of striated vs. smooth muscle sarcoglycan complex in limb-girdle muscular dystrophy. (Durbeej M, Sawatzki SM, Barresi R, Schmainda KM, Allamand V, Michele DE, Campbell KP) Proc Natl Acad Sci U S A 2003 Jul 22;100(15):8910-5 31 Citations |
1 | Effects of environmental enrichment on spatial memory and neurochemistry in middle-aged mice. (Frick KM, Stearns NA, Pan JY, Berger-Sweeney J) Learn Mem 2003;10(3):187-98 136 Citations |
2 | L-4F, an apolipoprotein A-1 mimetic, dramatically improves vasodilation in hypercholesterolemia and sickle cell disease. (Ou J, Ou Z, Jones DW, Holzhauer S, Hatoum OA, Ackerman AW, Weihrauch DW, Gutterman DD, Guice K, Oldham KT, Hillery CA, Pritchard KA Jr) Circulation 2003 May 13;107(18):2337-41 137 Citations |
1 | Enrichment enhances spatial memory and increases synaptophysin levels in aged female mice. (Frick KM, Fernandez SM) Neurobiol Aging 2003;24(4):615-26 260 Citations |
1 | Increased fibronectin deposition in embryonic hearts of retinol-binding protein-null mice. (Wendler CC, Schmoldt A, Flentke GR, Case LC, Quadro L, Blaner WS, Lough J, Smith SM) Circ Res 2003 May 02;92(8):920-8 30 Citations |
1 | Elimination of leukemia in the absence of lethal graft-versus-host disease after allogenic bone marrow transplantation. (Drobyski WR, Gendelman M, Vodanovic-Jankovic S, Gorski J) J Immunol 2003 Mar 15;170(6):3046-53 16 Citations |
1 | CD28 signal enhances apoptosis of CD8 T cells after strong TCR ligation. (Yu XZ, Martin PJ, Anasetti C) J Immunol 2003 Mar 15;170(6):3002-6 28 Citations |
1 | A threshold for central T cell tolerance to an inducible serum protein. (Haribhai D, Engle D, Meyer M, Donermeyer D, White JM, Williams CB) J Immunol 2003 Mar 15;170(6):3007-14 20 Citations |
2 | Mechanisms and implications of platelet discoid shape. (Italiano JE Jr, Bergmeier W, Tiwari S, Falet H, Hartwig JH, Hoffmeister KM, André P, Wagner DD, Shivdasani RA) Blood 2003 Jun 15;101(12):4789-96 137 Citations |
2 | The thrombomodulin-protein C system is essential for the maintenance of pregnancy. (Isermann B, Sood R, Pawlinski R, Zogg M, Kalloway S, Degen JL, Mackman N, Weiler H) Nat Med 2003 Mar;9(3):331-7 230 Citations |
2 | The clearance mechanism of chilled blood platelets. (Hoffmeister KM, Felbinger TW, Falet H, Denis CV, Bergmeier W, Mayadas TN, von Andrian UH, Wagner DD, Stossel TP, Hartwig JH) Cell 2003 Jan 10;112(1):87-97 370 Citations |
1 | Differential response properties of IB(4)-positive and -negative unmyelinated sensory neurons to protons and capsaicin. (Dirajlal S, Pauers LE, Stucky CL) J Neurophysiol 2003 Jan;89(1):513-24 130 Citations |
1 | Bcl-2 reduces mutant rates in a transgenic lacZ reporter gene in mouse pre-B lymphocytes. (Felix K, Rolink A, Melchers F, Janz S) Mutat Res 2003 Jan 28;522(1-2):135-44 3 Citations |
1 | Regulation of cyclooxygenase-2 expression by macrophages in response to double-stranded RNA and viral infection. (Steer SA, Moran JM, Maggi LB Jr, Buller RM, Perlman H, Corbett JA) J Immunol 2003 Jan 15;170(2):1070-6 43 Citations |
1 | Photochemical treatment of donor lymphocytes inhibited their ability to facilitate donor engraftment or increase donor chimerism after nonmyeloablative conditioning or establishment of mixed chimerism. (Johnson BD, Taylor PA, Stankowski MC, Talib S, Hearst JE, Blazar BR) Biol Blood Marrow Transplant 2002;8(11):581-7 |
1 | Structure of cerebral arterioles in cystathionine beta-synthase-deficient mice. (Baumbach GL, Sigmund CD, Bottiglieri T, Lentz SR) Circ Res 2002 Nov 15;91(10):931-7 63 Citations |
1 | Estrogen replacement improves spatial reference memory and increases hippocampal synaptophysin in aged female mice. (Frick KM, Fernandez SM, Bulinski SC) Neuroscience 2002;115(2):547-58 184 Citations |
1 | Real-time T-cell profiling identifies H60 as a major minor histocompatibility antigen in murine graft-versus-host disease. (Choi EY, Christianson GJ, Yoshimura Y, Jung N, Sproule TJ, Malarkannan S, Joyce S, Roopenian DC) Blood 2002 Dec 15;100(13):4259-65 62 Citations |
1 | Subunits of IgM reconstitute defective contact sensitivity in B-1 cell-deficient xid mice: kappa light chains recruit T cells independent of complement. (Paliwal V, Tsuji RF, Szczepanik M, Kawikova I, Campos RA, Kneilling M, Röcken M, Schuurman J, Redegeld FA, Nijkamp FP, Askenase PW) J Immunol 2002 Oct 15;169(8):4113-23 27 Citations |
1 | Novel role for calcium-independent phospholipase A(2) in the macrophage antiviral response of inducible nitric-oxide synthase expression. (Maggi LB Jr, Moran JM, Scarim AL, Ford DA, Yoon JW, McHowat J, Buller RM, Corbett JA) J Biol Chem 2002 Oct 11;277(41):38449-55 39 Citations |
1 | Conditioned place preference after single doses or "binge" cocaine in C57BL/6J and 129/J mice. (Zhang Y, Mantsch JR, Schlussman SD, Ho A, Kreek MJ) Pharmacol Biochem Behav 2002 Oct;73(3):655-62 |
1 | A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions. (Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, Sun M, Finton PJ, Shan L, Febbraio M, Hajjar DP, Silverstein RL, Hoff HF, Salomon RG, Hazen SL) J Biol Chem 2002 Oct 11;277(41):38517-23 341 Citations |
1 | Role of the passive apoptotic pathway in graft-versus-host disease. (Drobyski WR, Komorowski R, Logan B, Gendelman M) J Immunol 2002 Aug 01;169(3):1626-33 14 Citations |
1 | Neutralization of IL-18 attenuates lipopolysaccharide-induced myocardial dysfunction. (Raeburn CD, Dinarello CA, Zimmerman MA, Calkins CM, Pomerantz BJ, McIntyre RC Jr, Harken AH, Meng X) Am J Physiol Heart Circ Physiol 2002 Aug;283(2):H650-7 73 Citations |
1 | ICAM-1 and VCAM-1 mediate endotoxemic myocardial dysfunction independent of neutrophil accumulation. (Raeburn CD, Calkins CM, Zimmerman MA, Song Y, Ao L, Banerjee A, Harken AH, Meng X) Am J Physiol Regul Integr Comp Physiol 2002 Aug;283(2):R477-86 77 Citations |
1 | Structural characterization of Rasgrf1 and a novel linked imprinted locus. (de la Puente A, Hall J, Wu YZ, Leone G, Peters J, Yoon BJ, Soloway P, Plass C) Gene 2002 May 29;291(1-2):287-97 31 Citations |
1 | Glia- and neuron-specific expression of the renin-angiotensin system in brain alters blood pressure, water intake, and salt preference. (Morimoto S, Cassell MD, Sigmund CD) J Biol Chem 2002 Sep 06;277(36):33235-41 102 Citations |
1 | Decreased gallbladder response in leptin-deficient obese mice. (Goldblatt MI, Swartz-Basile DA, Svatek CL, Nakeeb A, Pitt HA) J Gastrointest Surg 2002;6(3):438-42; discussion 443-4 50 Citations |
1 | Soluble proteins and haptens on bone marrow-derived dendritic cells are presented to host CD4 T cells in an MHC-restricted manner. (Olasz EB, Linton J, Katz SI) Int Immunol 2002 May;14(5):493-502 4 Citations |
1 | Moderate G6PD deficiency increases mutation rates in the brain of mice. (Felix K, Rockwood LD, Pretsch W, Nair J, Bartsch H, Bornkamm GW, Janz S) Free Radic Biol Med 2002 Apr 01;32(7):663-73 20 Citations |
1 | Cellular sources and targets of IFN-gamma-mediated protection against viral demyelination and neurological deficits. (Murray PD, McGavern DB, Pease LR, Rodriguez M) Eur J Immunol 2002 Mar;32(3):606-15 30 Citations |
1 | Chemokine expression in the central nervous system of mice with a viral disease resembling multiple sclerosis: roles of CD4+ and CD8+ T cells and viral persistence. (Ransohoff RM, Wei T, Pavelko KD, Lee JC, Murray PD, Rodriguez M) J Virol 2002 Mar;76(5):2217-24 43 Citations |
1 | IL-6 transgenic mouse model for extraosseous plasmacytoma. (Kovalchuk AL, Kim JS, Park SS, Coleman AE, Ward JM, Morse HC 3rd, Kishimoto T, Potter M, Janz S) Proc Natl Acad Sci U S A 2002 Feb 05;99(3):1509-14 113 Citations |
1 | Differential cardiopulmonary recruitment of neutrophils during hemorrhagic shock: a role for ICAM-1? (Song Y, Ao L, Calkins CM, Raeburn CD, Harken AH, Meng X) Shock 2001 Dec;16(6):444-8 15 Citations |
1 | Sex differences in neurochemical markers that correlate with behavior in aging mice. (Frick KM, Burlingame LA, Delaney SS, Berger-Sweeney J) Neurobiol Aging 2002;23(1):145-58 35 Citations |
1 | Differential requirement for SLP-76 domains in T cell development and function. (Myung PS, Derimanov GS, Jordan MS, Punt JA, Liu QH, Judd BA, Meyers EE, Sigmund CD, Freedman BD, Koretzky GA) Immunity 2001 Dec;15(6):1011-26 89 Citations |
1 | Electrofusion of a weakly immunogenic neuroblastoma with dendritic cells produces a tumor vaccine. (Orentas RJ, Schauer D, Bin Q, Johnson BD) Cell Immunol 2001 Oct 10;213(1):4-13 56 Citations |
1 | The E2F1-3 transcription factors are essential for cellular proliferation. (Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G) Nature 2001 Nov 22;414(6862):457-62 506 Citations |
1 | Requirement for Ca2+/calmodulin-dependent kinase type IV/Gr in setting the thymocyte selection threshold. (Raman V, Blaeser F, Ho N, Engle DL, Williams CB, Chatila TA) J Immunol 2001 Dec 01;167(11):6270-8 24 Citations |
1 | Macrophage-specific expression of human lipoprotein lipase accelerates atherosclerosis in transgenic apolipoprotein e knockout mice but not in C57BL/6 mice. (Wilson K, Fry GL, Chappell DA, Sigmund CD, Medh JD) Arterioscler Thromb Vasc Biol 2001 Nov;21(11):1809-15 58 Citations |
1 | Characterization of a mouse model for thrombomodulin deficiency. (Weiler H, Lindner V, Kerlin B, Isermann BH, Hendrickson SB, Cooley BC, Meh DA, Mosesson MW, Shworak NW, Post MJ, Conway EM, Ulfman LH, von Andrian UH, Weitz JI) Arterioscler Thromb Vasc Biol 2001 Sep;21(9):1531-7 130 Citations |
1 | A low level of TNF-alpha mediates hemorrhage-induced acute lung injury via p55 TNF receptor. (Song Y, Ao L, Raeburn CD, Calkins CM, Abraham E, Harken AH, Meng X) Am J Physiol Lung Cell Mol Physiol 2001 Sep;281(3):L677-84 61 Citations |
1 | Vascular cell adhesion molecule--1 expression is obligatory for endotoxin-induced myocardial neutrophil accumulation and contractile dysfunction. (Raeburn CD, Calkins CM, Zimmerman MA, Song Y, Ao L, Banerjee A, Meng X, Harken AH) Surgery 2001 Aug;130(2):319-25 40 Citations |
1 | Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis. (Scarim AL, Arnush M, Blair LA, Concepcion J, Heitmeier MR, Scheuner D, Kaufman RJ, Ryerse J, Buller RM, Corbett JA) Am J Pathol 2001 Jul;159(1):273-83 50 Citations |
1 | Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice. (Dayal S, Bottiglieri T, Arning E, Maeda N, Malinow MR, Sigmund CD, Heistad DD, Faraci FM, Lentz SR) Circ Res 2001 Jun 08;88(11):1203-9 202 Citations |
1 | Mycobacterium bovis strain bacillus Calmette-Guérin-induced liver granulomas contain a diverse TCR repertoire, but a monoclonal T cell population is sufficient for protective granuloma formation. (Hogan LH, Macvilay K, Barger B, Co D, Malkovska I, Fennelly G, Sandor M) J Immunol 2001 May 15;166(10):6367-75 32 Citations |
1 | Anti-CD3 epsilon F(ab')2 prevents graft-versus-host disease by selectively depleting donor T cells activated by recipient alloantigens. (Yu XZ, Bidwell SJ, Martin PJ, Anasetti C) J Immunol 2001 May 01;166(9):5835-9 32 Citations |
1 | Protection from lethal murine graft-versus-host disease without compromise of alloengraftment using transgenic donor T cells expressing a thymidine kinase suicide gene. (Drobyski WR, Morse HC 3rd, Burns WH, Casper JT, Sandford G) Blood 2001 Apr 15;97(8):2506-13 26 Citations |
1 | Interleukin-6 promotes post-traumatic healing in the central nervous system. (Swartz KR, Liu F, Sewell D, Schochet T, Campbell I, Sandor M, Fabry Z) Brain Res 2001 Mar 30;896(1-2):86-95 145 Citations |
1 | Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets. (Blair LA, Heitmeier MR, Scarim AL, Maggi LB Jr, Corbett JA) Diabetes 2001 Feb;50(2):283-90 23 Citations |
1 | Targeted deletion of the A3 adenosine receptor confers resistance to myocardial ischemic injury and does not prevent early preconditioning. (Guo Y, Bolli R, Bao W, Wu WJ, Black RG Jr, Murphree SS, Salvatore CA, Jacobson MA, Auchampach JA) J Mol Cell Cardiol 2001 Apr;33(4):825-30 69 Citations |
1 | Spatial reference memory and neocortical neurochemistry vary with the estrous cycle in C57BL/6 mice. (Frick KM, Berger-Sweeney J) Behav Neurosci 2001 Feb;115(1):229-37 113 Citations |
1 | Quantitative analysis of the immune response to mouse non-MHC transplantation antigens in vivo: the H60 histocompatibility antigen dominates over all others. (Choi EY, Yoshimura Y, Christianson GJ, Sproule TJ, Malarkannan S, Shastri N, Joyce S, Roopenian DC) J Immunol 2001 Apr 01;166(7):4370-9 69 Citations |
1 | Mycobacterium bovis BCG-induced granuloma formation depends on gamma interferon and CD40 ligand but does not require CD28. (Hogan LH, Markofski W, Bock A, Barger B, Morrissey JD, Sandor M) Infect Immun 2001 Apr;69(4):2596-603 40 Citations |
1 | Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity. (Izadpanah A, Dwinell MB, Eckmann L, Varki NM, Kagnoff MF) Am J Physiol Gastrointest Liver Physiol 2001 Apr;280(4):G710-9 207 Citations |
1 | Preselective gene therapy for Fabry disease. (Qin G, Takenaka T, Telsch K, Kelley L, Howard T, Levade T, Deans R, Howard BH, Malech HL, Brady RO, Medin JA) Proc Natl Acad Sci U S A 2001 Mar 13;98(6):3428-33 66 Citations |
1 | Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cells. (Dwinell MB, Lügering N, Eckmann L, Kagnoff MF) Gastroenterology 2001 Jan;120(1):49-59 178 Citations |
1 | Inducible mutagenesis in TEPC 2372, a mouse plasmacytoma cell line that harbors the transgenic shuttle vector lambdaLIZ. (Felix K, Kovalchuk AL, Park SS, Coleman AE, Ramsay ES, Qian M, Kelliher KA, Jones GM, Ried T, Bornkamm GW, Janz S) Mutat Res 2001 Jan 25;473(1):121-36 1 Citation |
1 | Genetic variability in the response of normal murine hematopoietic progenitor cells to extracorporeal photochemotherapy. (Tsujino I, Sieber F) Photochem Photobiol 2000 Dec;72(6):810-4 4 Citations |
1 | Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. (Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM) Mol Microbiol 2001 Jan;39(2):330-40 40 Citations |
1 | Androgen-dependent regulation of human angiotensinogen expression in KAP-hAGT transgenic mice. (Ding Y, Sigmund CD) Am J Physiol Renal Physiol 2001 Jan;280(1):F54-60 47 Citations |
1 | Uptake and presentation of antigen to T cells by primary colonic epithelial cells in normal and diseased states. (Telega GW, Baumgart DC, Carding SR) Gastroenterology 2000 Dec;119(6):1548-59 33 Citations |
1 | Mice are not little rats: species differences in a one-day water maze task. (Frick KM, Stillner ET, Berger-Sweeney J) Neuroreport 2000 Nov 09;11(16):3461-5 138 Citations |
1 | Antitumor interaction of short-course endostatin and ionizing radiation. (Hanna NN, Seetharam S, Mauceri HJ, Beckett MA, Jaskowiak NT, Salloum RM, Hari D, Dhanabal M, Ramchandran R, Kalluri R, Sukhatme VP, Kufe DW, Weichselbaum RR) Cancer J 2000;6(5):287-93 61 Citations |
1 | Generation of antigen-specific, lacZ-inducible T-cell hybrids. (Malarkannan S, Mendoza LM, Shastri N) Methods Mol Biol 2001;156:265-72 18 Citations |
1 | Retinoic acid-mediated activation of the mouse renin enhancer. (Shi Q, Gross KW, Sigmund CD) J Biol Chem 2001 Feb 02;276(5):3597-603 59 Citations |
1 | Burkitt lymphoma in the mouse. (Kovalchuk AL, Qi CF, Torrey TA, Taddesse-Heath L, Feigenbaum L, Park SS, Gerbitz A, Klobeck G, Hoertnagel K, Polack A, Bornkamm GW, Janz S, Morse HC 3rd) J Exp Med 2000 Oct 16;192(8):1183-90 182 Citations |
1 | Contrast agent-enhanced magnetic resonance imaging of skeletal muscle damage in animal models of muscular dystrophy. (Straub V, Donahue KM, Allamand V, Davisson RL, Kim YR, Campbell KP) Magn Reson Med 2000 Oct;44(4):655-9 56 Citations |
1 | Differences that matter: major cytotoxic T cell-stimulating minor histocompatibility antigens. (Malarkannan S, Horng T, Eden P, Gonzalez F, Shih P, Brouwenstijn N, Klinge H, Christianson G, Roopenian D, Shastri N) Immunity 2000 Sep;13(3):333-44 76 Citations |
1 | The Mom1AKR intestinal tumor resistance region consists of Pla2g2a and a locus distal to D4Mit64. (Cormier RT, Bilger A, Lillich AJ, Halberg RB, Hong KH, Gould KA, Borenstein N, Lander ES, Dove WF) Oncogene 2000 Jun 29;19(28):3182-92 95 Citations |
1 | Defective uptake and utilization of long chain fatty acids in muscle and adipose tissues of CD36 knockout mice. (Coburn CT, Knapp FF Jr, Febbraio M, Beets AL, Silverstein RL, Abumrad NA) J Biol Chem 2000 Oct 20;275(42):32523-9 554 Citations |
1 | Adoptively transferred gamma delta T cells indirectly regulate murine graft-versus-host reactivity following donor leukocyte infusion therapy in mice. (Drobyski WR, Vodanovic-Jankovic S, Klein J) J Immunol 2000 Aug 01;165(3):1634-40 36 Citations |
1 | Biphasic and regionally-restricted chemokine expression in the central nervous system in the Theiler's virus model of multiple sclerosis. (Murray PD, Krivacic K, Chernosky A, Wei T, Ransohoff RM, Rodriguez M) J Neurovirol 2000 May;6 Suppl 1:S44-52 34 Citations |
1 | Deletion in the promoter region and altered expression of Pitx3 homeobox gene in aphakia mice. (Semina EV, Murray JC, Reiter R, Hrstka RF, Graw J) Hum Mol Genet 2000 Jul 01;9(11):1575-85 162 Citations |
1 | Viewpoint: are studies in genetically altered mice out of control? (Sigmund CD) Arterioscler Thromb Vasc Biol 2000 Jun;20(6):1425-9 109 Citations |
1 | Ligand-specific selection of MHC class II-restricted thymocytes in fetal thymic organ culture. (Kersh GJ, Engle DL, Williams CB, Allen PM) J Immunol 2000 Jun 01;164(11):5675-82 10 Citations |
1 | CD28-specific antibody prevents graft-versus-host disease in mice. (Yu XZ, Bidwell SJ, Martin PJ, Anasetti C) J Immunol 2000 May 01;164(9):4564-8 79 Citations |
1 | Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species. (Podrez EA, Febbraio M, Sheibani N, Schmitt D, Silverstein RL, Hajjar DP, Cohen PA, Frazier WA, Hoff HF, Hazen SL) J Clin Invest 2000 Apr;105(8):1095-108 378 Citations |
1 | Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice. (Febbraio M, Podrez EA, Smith JD, Hajjar DP, Hazen SL, Hoff HF, Sharma K, Silverstein RL) J Clin Invest 2000 Apr;105(8):1049-56 859 Citations |
1 | Targeted overactivity of beta cell K(ATP) channels induces profound neonatal diabetes. (Koster JC, Marshall BA, Ensor N, Corbett JA, Nichols CG) Cell 2000 Mar 17;100(6):645-54 257 Citations |
1 | Contrasting blood pressure effects of obesity in leptin-deficient ob/ob mice and agouti yellow obese mice. (Mark AL, Shaffer RA, Correia ML, Morgan DA, Sigmund CD, Haynes WG) J Hypertens 1999 Dec;17(12 Pt 2):1949-53 233 Citations |
1 | Axonal loss results in spinal cord atrophy, electrophysiological abnormalities and neurological deficits following demyelination in a chronic inflammatory model of multiple sclerosis. (McGavern DB, Murray PD, Rivera-Quiñones C, Schmelzer JD, Low PA, Rodriguez M) Brain 2000 Mar;123 Pt 3(Pt 3):519-31 116 Citations |
1 | Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. (Norment AM, Bogatzki LY, Gantner BN, Bevan MJ) J Immunol 2000 Jan 15;164(2):639-48 92 Citations |
1 | Reference memory, anxiety and estrous cyclicity in C57BL/6NIA mice are affected by age and sex. (Frick KM, Burlingame LA, Arters JA, Berger-Sweeney J) Neuroscience 2000;95(1):293-307 217 Citations |
1 | Primary megakaryocytes reveal a role for transcription factor NF-E2 in integrin alpha IIb beta 3 signaling. (Shiraga M, Ritchie A, Aidoudi S, Baron V, Wilcox D, White G, Ybarrondo B, Murphy G, Leavitt A, Shattil S) J Cell Biol 1999 Dec 27;147(7):1419-30 78 Citations |
1 | Role of immunoregulatory donor T cells in suppression of graft-versus-host disease following donor leukocyte infusion therapy. (Johnson BD, Becker EE, LaBelle JL, Truitt RL) J Immunol 1999 Dec 15;163(12):6479-87 62 Citations |
1 | Photochemical treatment with S-59 psoralen and ultraviolet A light to control the fate of naive or primed T lymphocytes in vivo after allogeneic bone marrow transplantation. (Truitt RL, Johnson BD, Hanke C, Talib S, Hearst JE) J Immunol 1999 Nov 01;163(9):5145-56 48 Citations |
1 | Visualization, fate, and pathogenicity of antigen-specific CD8+ T cells in the graft-versus-host reaction. (Yu XZ, Bidwell S, Martin PJ, Anasetti C) J Immunol 1999 Nov 01;163(9):4780-7 14 Citations |
1 | Cytogenetic analysis of the bipotential murine pre-B cell lymphoma, P388, and its derivative macrophage-like tumor, P388D1, using SKY and CGH. (Coleman AE, Forest ST, McNeil N, Kovalchuk AL, Ried T, Janz S) Leukemia 1999 Oct;13(10):1592-600 14 Citations |
1 | Graft-facilitating doses of ex vivo activated gammadelta T cells do not cause lethal murine graft-vs.-host disease. (Drobyski WR, Majewski D, Hanson G) Biol Blood Marrow Transplant 1999;5(4):222-30 59 Citations |
1 | Elevated mutant frequencies in lymphoid tissues persist throughout plasmacytoma development in BALB/c.lambdaLIZ mice. (Felix K, Kelliher KA, Bornkamm GW, Janz S) Cancer Res 1999 Aug 01;59(15):3621-6 10 Citations |
1 | Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOS-deficient mice. (Lake-Bruse KD, Faraci FM, Shesely EG, Maeda N, Sigmund CD, Heistad DD) Am J Physiol 1999 Aug;277(2):H770-6 52 Citations |
1 | Isolectin B(4)-positive and -negative nociceptors are functionally distinct. (Stucky CL, Lewin GR) J Neurosci 1999 Aug 01;19(15):6497-505 392 Citations |
1 | Graft-vs.-host and graft-vs.-leukemia reactions after delayed infusions of donor T-subsets. (Johnson BD, Becker EE, Truitt RL) Biol Blood Marrow Transplant 1999;5(3):123-32 54 Citations |
1 | A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. (Febbraio M, Abumrad NA, Hajjar DP, Sharma K, Cheng W, Pearce SF, Silverstein RL) J Biol Chem 1999 Jul 02;274(27):19055-62 671 Citations |
1 | CNS cell populations are protected from virus-induced pathology by distinct arms of the immune system. (Drescher KM, Murray PD, David CS, Pease LR, Rodriguez M) Brain Pathol 1999 Jan;9(1):21-31 23 Citations |
1 | Absence of spontaneous central nervous system remyelination in class II-deficient mice infected with Theiler's virus. (Njenga MK, Murray PD, McGavern D, Lin X, Drescher KM, Rodriguez M) J Neuropathol Exp Neurol 1999 Jan;58(1):78-91 31 Citations |
1 | Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat. (Dawson DW, Volpert OV, Pearce SF, Schneider AJ, Silverstein RL, Henkin J, Bouck NP) Mol Pharmacol 1999 Feb;55(2):332-8 137 Citations |
1 | Kidney is the only source of human plasma renin in 45-kb human renin transgenic mice. (Yan Y, Chen R, Pitarresi T, Sigmund CD, Gross KW, Sealey JE, Laragh JH, Catanzaro DF) Circ Res 1998 Dec 14-28;83(12):1279-88 27 Citations |
1 | Role of CD28 in acute graft-versus-host disease. (Yu XZ, Martin PJ, Anasetti C) Blood 1998 Oct 15;92(8):2963-70 58 Citations |
1 | The molecular and functional characterization of a dominant minor H antigen, H60. (Malarkannan S, Shih PP, Eden PA, Horng T, Zuberi AR, Christianson G, Roopenian D, Shastri N) J Immunol 1998 Oct 01;161(7):3501-9 212 Citations |
1 | Perforin-dependent neurologic injury in a viral model of multiple sclerosis. (Murray PD, McGavern DB, Lin X, Njenga MK, Leibowitz J, Pease LR, Rodriguez M) J Neurosci 1998 Sep 15;18(18):7306-14 98 Citations |
1 | Functional activity of epidermal growth factor receptors in autosomal recessive polycystic kidney disease. (Sweeney WE Jr, Avner ED) Am J Physiol 1998 Sep;275(3):F387-94 92 Citations |
1 | Ex vivo anti-CD3 antibody-activated donor T cells have a reduced ability to cause lethal murine graft-versus-host disease but retain their ability to facilitate alloengraftment. (Drobyski WR, Majewski D, Ozker K, Hanson G) J Immunol 1998 Sep 01;161(5):2610-9 46 Citations |
1 | CD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis. (Murray PD, Pavelko KD, Leibowitz J, Lin X, Rodriguez M) J Virol 1998 Sep;72(9):7320-9 110 Citations |
1 | In vivo expression of a TCR antagonist: T cells escape central tolerance but are antagonized in the periphery. (Williams CB, Vidal K, Donermeyer D, Peterson DA, White JM, Allen PM) J Immunol 1998 Jul 01;161(1):128-37 30 Citations |
1 | Theiler's virus infection of genetically susceptible mice induces central nervous system-infiltrating CTLs with no apparent viral or major myelin antigenic specificity. (Lin X, Pease LR, Murray PD, Rodriguez M) J Immunol 1998 Jun 01;160(11):5661-8 32 Citations |
1 | Glycosphingolipids as novel targets for T-cell suppression by the B subunit of recombinant heat-labile enterotoxin. (Truitt RL, Hanke C, Radke J, Mueller R, Barbieri JT) Infect Immun 1998 Apr;66(4):1299-308 35 Citations |
1 | Compensatory prostaglandin E2 biosynthesis in cyclooxygenase 1 or 2 null cells. (Kirtikara K, Morham SG, Raghow R, Laulederkind SJ, Kanekura T, Goorha S, Ballou LR) J Exp Med 1998 Feb 16;187(4):517-23 124 Citations |
1 | Cadmium decreases SGLT1 messenger RNA in mouse kidney cells. (Blumenthal SS, Ren L, Lewand DL, Krezoski SK, Petering DH) Toxicol Appl Pharmacol 1998 Mar;149(1):49-54 16 Citations |
1 | Regulatory elements required for human angiotensinogen expression in HepG2 cells are dispensable in transgenic mice. (Yang G, Sigmund CD) Hypertension 1998 Mar;31(3):734-40 21 Citations |
1 | Resistance to and recovery from lethal influenza virus infection in B lymphocyte-deficient mice. (Graham MB, Braciale TJ) J Exp Med 1997 Dec 15;186(12):2063-8 201 Citations |
1 | Isolation of a new homeobox gene belonging to the Pitx/Rieg family: expression during lens development and mapping to the aphakia region on mouse chromosome 19. (Semina EV, Reiter RS, Murray JC) Hum Mol Genet 1997 Nov;6(12):2109-16 170 Citations |
1 | Elevated mutant frequencies in gene lacI in splenic lipopolysaccharide blasts after exposure to activated phagocytes in vitro. (Felix K, Lin S, Janz S) Eur J Immunol 1997 Sep;27(9):2160-4 5 Citations |
1 | Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes. (Davisson RL, Kim HS, Krege JH, Lager DJ, Smithies O, Sigmund CD) J Clin Invest 1997 Mar 15;99(6):1258-64 66 Citations |
1 | Donor gamma delta T lymphocytes promote allogeneic engraftment across the major histocompatibility barrier in mice. (Drobyski WR, Majewski D) Blood 1997 Feb 01;89(3):1100-9 39 Citations |
1 | Increased interleukin-6 production by cerebral cortical tissue of adult versus young mice. (Prechel MM, Halbur L, Devata S, Vaidya AM, Young MR) Mech Ageing Dev 1996 Dec 20;92(2-3):185-94 27 Citations |
1 | Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease. (Pewe L, Wu GF, Barnett EM, Castro RF, Perlman S) Immunity 1996 Sep;5(3):253-62 83 Citations |
1 | Delayed-type hypersensitivity in mast cell-deficient mice: dependence on platelets for expression of contact sensitivity. (Geba GP, Ptak W, Anderson GM, Paliwal V, Ratzlaff RE, Levin J, Askenase PW) J Immunol 1996 Jul 15;157(2):557-65 88 Citations |
1 | Treatment of donor mice with an alpha beta T-cell receptor monoclonal antibody induces prolonged T-cell nonresponsiveness and effectively prevents lethal graft-versus-host disease in murine recipients of major histocompatibility complex (MHC)-matched and MHC-mismatched donor marrow grafts. (Drobyski WR, Majewski D) Blood 1996 Jun 15;87(12):5355-69 11 Citations |
1 | Silicone-induced T cell proliferation in mice. (McDonald AH, Weir K, Sanger JR) Curr Top Microbiol Immunol 1996;210:189-98 8 Citations |
1 | A rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells. (Malarkannan S, Afkarian M, Shastri N) J Exp Med 1995 Dec 01;182(6):1739-50 63 Citations |
1 | Potentiation of merocyanine 540-mediated photodynamic therapy by salicylate and related drugs. (Traul DL, Anderson GS, Bilitz JM, Krieg M, Sieber F) Photochem Photobiol 1995 Oct;62(4):790-9 7 Citations |
1 | Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. (Orellana SA, Sweeney WE, Neff CD, Avner ED) Kidney Int 1995 Feb;47(2):490-9 128 Citations |
1 | Localization of the murine homolog of the anaplastic lymphoma kinase (AlK) gene on mouse chromosome 17. (Mathew P, Morris SW, Kane JR, Shurtleff SA, Pasquini M, Jenkins NA, Gilbert DJ, Copeland NG) Cytogenet Cell Genet 1995;70(1-2):143-4 11 Citations |
1 | Functional expression of the human angiotensinogen gene in transgenic mice. (Yang G, Merrill DC, Thompson MW, Robillard JE, Sigmund CD) J Biol Chem 1994 Dec 23;269(51):32497-502 112 Citations |
1 | Pharmacological enhancement of in vivo foreign gene expression in muscle. (Danko I, Fritz JD, Jiao S, Hogan K, Latendresse JS, Wolff JA) Gene Ther 1994 Mar;1(2):114-21 143 Citations |
1 | Periocular and urogenital lesions in mice (Mus musculus) chronically infected with Trypanosoma brucei. (Shapiro SZ, Thulin JD, Morton DG) Lab Anim Sci 1994 Feb;44(1):76-8 3 Citations |
1 | Dystrophin expression improves myofiber survival in mdx muscle following intramuscular plasmid DNA injection. (Danko I, Fritz JD, Latendresse JS, Herweijer H, Schultz E, Wolff JA) Hum Mol Genet 1993 Dec;2(12):2055-61 70 Citations |
1 | Response to influenza infection in mice with a targeted disruption in the interferon gamma gene. (Graham MB, Dalton DK, Giltinan D, Braciale VL, Stewart TA, Braciale TJ) J Exp Med 1993 Nov 01;178(5):1725-32 224 Citations |
1 | Expression of the human renin gene in transgenic mice throughout ontogeny. (Sigmund CD) Pediatr Nephrol 1993 Oct;7(5):639-45 16 Citations |
1 | The olfactory nerve and not the trigeminal nerve is the major site of CNS entry for mouse hepatitis virus, strain JHM. (Barnett EM, Perlman S) Virology 1993 May;194(1):185-91 85 Citations |
1 | Epithelial polarity and differentiation in polycystic kidney disease. (Avner ED) J Cell Sci Suppl 1993;17:217-22 36 Citations |
1 | Mouse hepatitis virus and herpes simplex virus move along different CNS pathways. (Perlman S, Barnett E, Jacobsen G) Adv Exp Med Biol 1993;342:313-8 8 Citations |
1 | Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease. (Avner ED, Sweeney WE Jr, Nelson WJ) Proc Natl Acad Sci U S A 1992 Aug 15;89(16):7447-51 98 Citations |
1 | Allele-specific expression of the murine Ren-1 genes. (Fabian JR, Field LJ, McGowan RA, Mullins JJ, Sigmund CD, Gross KW) J Biol Chem 1989 Oct 15;264(29):17589-94 44 Citations |
1 | [Epidermal growth factor with insulin used for stimulation of exogenous colony formation in the spleen of mice irradiated with lethal doses of X-rays]. (Gracheva NI, Zhestianikov VD, Bil'din VN, Pereverzev AE, Sorokin AB) Tsitologiia 1988 Jan;30(1):58-61 |
1 | Evidence that stimulation of 1,25(OH)2D3 production in primary cultures of mouse kidney cells by cyclic AMP requires new protein synthesis. (Korkor AB, Gray RW, Henry HL, Kleinman JG, Blumenthal SS, Garancis JC) J Bone Miner Res 1987 Dec;2(6):517-24 28 Citations |
1 | Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation. (Avner ED, Studnicki FE, Young MC, Sweeney WE Jr, Piesco NP, Ellis D, Fettermann GH) Pediatr Nephrol 1987 Oct;1(4):587-96 54 Citations |
1 | Dye-mediated photosensitization of murine neuroblastoma cells. (Sieber F, Sieber-Blum M) Cancer Res 1986 Apr;46(4 Pt 2):2072-6 68 Citations |
1 | Regression of genetically determined polycystic kidney disease in murine organ culture. (Avner ED, Sweeney WE Jr, Piesco NP, Ellis D) Experientia 1986 Jan 15;42(1):77-80 15 Citations |
1 | Genetic control of immune response to sperm whale myoglobin in mice. I. T lymphocyte proliferative response under H-2-linked Ir gene control. (Okuda K, Christadoss PR, Twining S, Atassi MZ, David CS) J Immunol 1978 Sep;121(3):866-8 67 Citations |