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| 4 | Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice. (Ritter ML, Deng G, Reho JJ, Deng Y, Sapouckey SA, Opichka MA, Balapattabi K, Wackman KK, Brozoski DT, Lu KT, Paradee WJ, Gibson-Corley KN, Cui H, Nakagawa P, Morselli LL, Sigmund CD, Grobe JL) Hypertension 2022 Dec;79(12):2843-2853 1 Citation |
| 1 | Activation of the Central Renin-Angiotensin System Causes Local Cerebrovascular Dysfunction. (De Silva TM, Modrick ML, Grobe JL, Faraci FM) Stroke 2021 Jul;52(7):2404-2413 8 Citations |
| 3 | β-Arrestin-Biased Agonist Targeting the Brain AT1R (Angiotensin II Type 1 Receptor) Increases Aversion to Saline and Lowers Blood Pressure in Deoxycorticosterone Acetate-Salt Hypertension. (Zanaty M, Seara FAC, Nakagawa P, Deng G, Mathieu NM, Balapattabi K, Karnik SS, Grobe JL, Sigmund CD) Hypertension 2021 Feb;77(2):420-431 14 Citations |
| 1 | 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhibitor, lowers L-NAME-induced hypertension through suppression of angiotensin-converting enzyme in rats. (Bukhari IA, Alorainey BI, Al-Motrefi AA, Mahmoud A, Campbell WB, Hammock BD) Eur Rev Med Pharmacol Sci 2020 Aug;24(15):8143-8150 5 Citations |
| 1 | Interaction between Mas1 and AT1RA contributes to enhancement of skeletal muscle angiogenesis by angiotensin-(1-7) in Dahl salt-sensitive rats. (Exner EC, Geurts AM, Hoffmann BR, Casati M, Stodola T, Dsouza NR, Zimmermann M, Lombard JH, Greene AS) PLoS One 2020;15(4):e0232067 7 Citations |
| 1 | Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations. (Wingler LM, Elgeti M, Hilger D, Latorraca NR, Lerch MT, Staus DP, Dror RO, Kobilka BK, Hubbell WL, Lefkowitz RJ) Cell 2019 Jan 24;176(3):468-478.e11 171 Citations |
| 1 | The renin-angiotensin system in the arcuate nucleus controls resting metabolic rate. (Deng G, Grobe JL) Curr Opin Nephrol Hypertens 2019 Mar;28(2):120-127 13 Citations |
| 2 | Control of Energy Expenditure by AgRP Neurons of the Arcuate Nucleus: Neurocircuitry, Signaling Pathways, and Angiotensin. (Morselli LL, Claflin KE, Cui H, Grobe JL) Curr Hypertens Rep 2018 Mar 19;20(3):25 26 Citations |
| 2 | Angiotensin AT1A receptors expressed in vasopressin-producing cells of the supraoptic nucleus contribute to osmotic control of vasopressin. (Sandgren JA, Linggonegoro DW, Zhang SY, Sapouckey SA, Claflin KE, Pearson NA, Leidinger MR, Pierce GL, Santillan MK, Gibson-Corley KN, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2018 Jun 01;314(6):R770-R780 30 Citations |
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| 1 | Angiotensin AT1A receptors on leptin receptor-expressing cells control resting metabolism. (Claflin KE, Sandgren JA, Lambertz AM, Weidemann BJ, Littlejohn NK, Burnett CM, Pearson NA, Morgan DA, Gibson-Corley KN, Rahmouni K, Grobe JL) J Clin Invest 2017 Apr 03;127(4):1414-1424 57 Citations |
| 1 | AT2R autoantibodies block angiotensin II and AT1R autoantibody-induced vasoconstriction. (Liles C, Li H, Veitla V, Liles JT, Murphy TA, Cunningham MW, Yu X, Kem DC) Hypertension 2015 Oct;66(4):830-5 15 Citations |
| 1 | Structure of the Angiotensin receptor revealed by serial femtosecond crystallography. (Zhang H, Unal H, Gati C, Han GW, Liu W, Zatsepin NA, James D, Wang D, Nelson G, Weierstall U, Sawaya MR, Xu Q, Messerschmidt M, Williams GJ, Boutet S, Yefanov OM, White TA, Wang C, Ishchenko A, Tirupula KC, Desnoyer R, Coe J, Conrad CE, Fromme P, Stevens RC, Katritch V, Karnik SS, Cherezov V) Cell 2015 May 07;161(4):833-44 296 Citations |
| 1 | Novel retro-inverso peptide inhibitor reverses angiotensin receptor autoantibody-induced hypertension in the rabbit. (Li H, Kem DC, Zhang L, Huang B, Liles C, Benbrook A, Gali H, Veitla V, Scherlag BJ, Cunningham MW, Yu X) Hypertension 2015 Apr;65(4):793-9 25 Citations |
| 1 | Prevalence of angiotensin II type 1 receptor (AT1R)-activating autoantibodies in primary aldosteronism. (Li H, Yu X, Cicala MV, Mantero F, Benbrook A, Veitla V, Cunningham MW, Kem DC) J Am Soc Hypertens 2015 Jan;9(1):15-20 27 Citations |
| 2 | Role of vascular smooth muscle PPARγ in regulating AT1 receptor signaling and angiotensin II-dependent hypertension. (Carrillo-Sepulveda MA, Keen HL, Davis DR, Grobe JL, Sigmund CD) PLoS One 2014;9(8):e103786 11 Citations |
| 1 | Response to "Does angiotensin-dependent superoxide production help to prevent salt-induced endothelial dysfunction in 2 kidney-1 clip hypertensive rats?". (Beyer AM, Fredrich K, Lombard JH) Am J Hypertens 2014 Apr;27(4):640 |
| 1 | AT1 receptors prevent salt-induced vascular dysfunction in isolated middle cerebral arteries of 2 kidney-1 clip hypertensive rats. (Beyer AM, Fredrich K, Lombard JH) Am J Hypertens 2013 Dec;26(12):1398-404 9 Citations |
| 1 | Real-time electrochemical detection of ATP and H₂O₂ release in freshly isolated kidneys. (Palygin O, Levchenko V, Ilatovskaya DV, Pavlov TS, Ryan RP, Cowley AW Jr, Staruschenko A) Am J Physiol Renal Physiol 2013 Jul 01;305(1):F134-41 32 Citations |
| 2 | Angiotensin type 1a receptors in the subfornical organ are required for deoxycorticosterone acetate-salt hypertension. (Hilzendeger AM, Cassell MD, Davis DR, Stauss HM, Mark AL, Grobe JL, Sigmund CD) Hypertension 2013 Mar;61(3):716-22 54 Citations |
| 2 | A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity. (Hilzendeger AM, Morgan DA, Brooks L, Dellsperger D, Liu X, Grobe JL, Rahmouni K, Sigmund CD, Mark AL) Am J Physiol Heart Circ Physiol 2012 Jul 15;303(2):H197-206 98 Citations |
| 2 | Renal proximal tubule angiotensin AT1A receptors regulate blood pressure. (Li H, Weatherford ET, Davis DR, Keen HL, Grobe JL, Daugherty A, Cassis LA, Allen AM, Sigmund CD) Am J Physiol Regul Integr Comp Physiol 2011 Oct;301(4):R1067-77 73 Citations |
| 1 | Role of integrins in angiotensin II-induced proliferation of vascular smooth muscle cells. (Bunni MA, Kramarenko II, Walker L, Raymond JR, Garnovskaya MN) Am J Physiol Cell Physiol 2011 Mar;300(3):C647-56 22 Citations |
| 1 | Ischemia-induced brain damage is enhanced in human renin and angiotensinogen double-transgenic mice. (Chen S, Li G, Zhang W, Wang J, Sigmund CD, Olson JE, Chen Y) Am J Physiol Regul Integr Comp Physiol 2009 Nov;297(5):R1526-31 38 Citations |
| 1 | Angiotensin II maintains cerebral vascular relaxation via EGF receptor transactivation and ERK1/2. (McEwen ST, Balus SF, Durand MJ, Lombard JH) Am J Physiol Heart Circ Physiol 2009 Oct;297(4):H1296-303 17 Citations |
| 1 | Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging. (Modrick ML, Didion SP, Sigmund CD, Faraci FM) Am J Physiol Heart Circ Physiol 2009 Jun;296(6):H1914-9 90 Citations |
| 2 | Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide. (Gauthier KM, Zhang DX, Cui L, Nithipatikom K, Campbell WB) Hypertension 2008 Jul;52(1):150-5 13 Citations |
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| 1 | Targeting brain AT1 receptors by RNA interference. (Sigmund CD, Davisson RL) Hypertension 2006 Feb;47(2):145-6 5 Citations |
| 1 | Cerebral vascular effects of angiotensin II: new insights from genetic models. (Faraci FM, Lamping KG, Modrick ML, Ryan MJ, Sigmund CD, Didion SP) J Cereb Blood Flow Metab 2006 Apr;26(4):449-55 85 Citations |
| 1 | Effects of cytokine treatment on angiotensin II type 1A receptor transcription and splicing in rat cardiac fibroblasts. (Cowling RT, Zhang X, Reese VC, Iwata M, Gurantz D, Dillmann WH, Greenberg BH) Am J Physiol Heart Circ Physiol 2005 Sep;289(3):H1176-83 24 Citations |
| 2 | Chronic administration of nitric oxide reduces angiotensin II receptor type 1 expression and aldosterone synthesis in zona glomerulosa cells. (Nithipatikom K, Holmes BB, McCoy MJ, Hillard CJ, Campbell WB) Am J Physiol Endocrinol Metab 2004 Nov;287(5):E820-7 11 Citations |
| 1 | Adjacent expression of renin and angiotensinogen in the rostral ventrolateral medulla using a dual-reporter transgenic model. (Lavoie JL, Cassell MD, Gross KW, Sigmund CD) Hypertension 2004 May;43(5):1116-9 72 Citations |
| 1 | Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice. (Ryan MJ, Didion SP, Mathur S, Faraci FM, Sigmund CD) Hypertension 2004 May;43(5):1074-9 72 Citations |
| 1 | Late-gestation betamethasone enhances coronary artery responsiveness to angiotensin II in fetal sheep. (Roghair RD, Lamb FS, Bedell KA, Smith OM, Scholz TD, Segar JL) Am J Physiol Regul Integr Comp Physiol 2004 Jan;286(1):R80-8 21 Citations |
| 1 | Effects of the AT1-receptor antagonist eprosartan on the progression of left ventricular dysfunction in dogs with heart failure. (Suzuki G, Mishima T, Tanhehco EJ, Sharov VG, Todor A, Rostogi S, Gupta RC, Chaudhry PA, Anagnostopoulos PV, Nass O, Goldstein S, Sabbah HN) Br J Pharmacol 2003 Jan;138(2):301-9 9 Citations |
| 1 | Stage-dependent activation of cell cycle and apoptosis mechanisms in the right ventricle by pressure overload. (Ecarnot-Laubriet A, Assem M, Poirson-Bichat F, Moisant M, Bernard C, Lecour S, Solary E, Rochette L, Teyssier JR) Biochim Biophys Acta 2002 Apr 24;1586(3):233-42 28 Citations |
| 1 | Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice. (Lazartigues E, Dunlay SM, Loihl AK, Sinnayah P, Lang JA, Espelund JJ, Sigmund CD, Davisson RL) Circ Res 2002 Mar 22;90(5):617-24 69 Citations |
| 1 | Angiotensin II blockade reduces radiation-induced proliferation in experimental radiation nephropathy. (Moulder JE, Fish BL, Regner KR, Cohen EP) Radiat Res 2002 Apr;157(4):393-401 24 Citations |
| 1 | Responses of fetal ovine systemic and umbilical arteries to angiotensin II. (Segar JL, Barna TJ, Acarregui MJ, Lamb FS) Pediatr Res 2001 Jun;49(6):826-33 16 Citations |
| 1 | Central AT1 and AT2 receptors mediate chronic intracerebroventricular angiotensin II-induced drinking in rats fed high sodium chloride diet from weaning. (Camara AK, Osborn J) Acta Physiol Scand 2001 Feb;171(2):195-201 19 Citations |
| 1 | A cDNA from human bone marrow encoding a protein exhibiting homology to the ATP1gamma1/PLM/MAT8 family of transmembrane proteins. (Omasa T, Chen YG, Mantalaris A, Wu JH) Biochim Biophys Acta 2001 Jan 26;1517(2):307-10 2 Citations |
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| 1 | Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice. (Davisson RL, Ding Y, Stec DE, Catterall JF, Sigmund CD) Physiol Genomics 1999 Jul 15;1(1):3-9 109 Citations |
| 1 | Divergent functions of angiotensin II receptor isoforms in the brain. (Davisson RL, Oliverio MI, Coffman TM, Sigmund CD) J Clin Invest 2000 Jul;106(1):103-6 163 Citations |
| 1 | Factors contributing to pressure overload-induced immediate early gene expression in adult rat hearts in vivo. (Ogino K, Cai B, Gu A, Kohmoto T, Yamamoto N, Burkhoff D) Am J Physiol 1999 Jul;277(1):H380-7 8 Citations |
