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Mesh term Placenta Growth Factor

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Pregnancy Proteins
Vascular Endothelial Growth Factors

Description

An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.



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jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad