Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term Antidepressive Agents, Tricyclic

Browse to parent terms:
Antidepressive Agents

Description

Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.



Search for this term in our Faculty Database



View this term at the NCBI website
jenkins-FCD Prod-332 f92a19b0ec5e8e1eff783fac390ec127e367c2b5