Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term Epidermal Growth Factor

Browse to parent terms:
EGF Family of Proteins
Gastrointestinal Hormones

Description

A 6-kDa polypeptide growth factor initially discovered in mouse submaxillary glands. Human epidermal growth factor was originally isolated from urine based on its ability to inhibit gastric secretion and called urogastrone. Epidermal growth factor exerts a wide variety of biological effects including the promotion of proliferation and differentiation of mesenchymal and EPITHELIAL CELLS. It is synthesized as a transmembrane protein which can be cleaved to release a soluble active form.



Search for this term in our Faculty Database



View this term at the NCBI website
jenkins-FCD Prod-200 8231f2114cbb5b433e24eeafff71f933aa5694c5