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Mesh term Ferrochelatase

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Iron-Sulfur Proteins
Lyases
Mitochondrial Proteins

Description

A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME. Ferrochelatase catalyzes ferrous insertion into protoporphyrin IX to form protoheme or heme. Deficiency in this enzyme results in ERYTHROPOIETIC PROTOPORPHYRIA.



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View this term at the NCBI website
jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad