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Mesh term Multiple Sclerosis

Browse to parent terms:
Demyelinating Autoimmune Diseases, CNS

Description

An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)


Browse to child terms:
Multiple Sclerosis, Chronic Progressive
Multiple Sclerosis, Relapsing-Remitting


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View this term at the NCBI website
jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6