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Mesh term Nucleic Acid Hybridization

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Biochemical Phenomena
Genetic Techniques

Description

Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)


Browse to child terms:
Base Pairing
Branched DNA Signal Amplification Assay
Comparative Genomic Hybridization
Heteroduplex Analysis
In Situ Hybridization
Oligonucleotide Array Sequence Analysis
Subtractive Hybridization Techniques


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jenkins-FCD Prod-200 8231f2114cbb5b433e24eeafff71f933aa5694c5