Mesh term Pro-Opiomelanocortin
Browse to parent terms:Hypothalamic Hormones
Pituitary Hormones, Anterior
Protein Precursors
Description
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).Browse to child terms:
Corticotropin-Like Intermediate Lobe Peptide
Melanocortins
alpha-Endorphin
alpha-MSH
beta-Endorphin
beta-Lipotropin
beta-MSH
gamma-Endorphin
gamma-Lipotropin
gamma-MSH
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