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Mesh term Renin

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Aspartic Acid Endopeptidases
Proprotein Convertases

Description

A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.



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jenkins-FCD Prod-254 d4c00de02f1a46783a560ec8b3cebd5f74857048