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Mesh term HLA-C Antigens

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HLA Antigens
Histocompatibility Antigens Class I

Description

Class I human histocompatibility (HLA) antigens encoded by a small cluster of structural genes at the C locus on chromosome 6. They have significantly lower immunogenicity than the HLA-A and -B determinants and are therefore of minor importance in donor/recipient crossmatching. Their primary role is their high-risk association with certain disease manifestations (e.g., spondylarthritis, psoriasis, multiple myeloma).



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jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad