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Mesh term Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Browse to parent terms:
Leukemia, Myeloid
Myeloproliferative Disorders

Description

Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.


Browse to child terms:
Blast Crisis
Leukemia, Myeloid, Accelerated Phase
Leukemia, Myeloid, Chronic-Phase


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View this term at the NCBI website
jenkins-FCD Prod-321 98992d628744e349846c2f62ac68f241d7e1ea70