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Mesh term Lewy Bodies

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Inclusion Bodies
Neurons

Description

Intracytoplasmic, eosinophilic, round to elongated inclusions found in vacuoles of injured or fragmented neurons. The presence of Lewy bodies is the histological marker of the degenerative changes in LEWY BODY DISEASE and PARKINSON DISEASE but they may be seen in other neurological conditions. They are typically found in the substantia nigra and locus coeruleus but they are also seen in the basal forebrain, hypothalamic nuclei, and neocortex.



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jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad