Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term Ki-1 Antigen

Browse to parent terms:
Antigens, Neoplasm
Biomarkers, Tumor
Receptors, Tumor Necrosis Factor

Description

A member of the tumor necrosis factor receptor superfamily that may play a role in the regulation of NF-KAPPA B and APOPTOSIS. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; NEUTROPHILS; EOSINOPHILS; MAST CELLS and NK CELLS. Overexpression of the Ki-1 antigen in hematopoietic malignancies make it clinically useful as a biological tumor marker. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.



Search for this term in our Faculty Database



View this term at the NCBI website
jenkins-FCD Prod-336 69ef4a6b262d135130251597d5d39873903802b5