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Mesh term Receptors, Cytoplasmic and Nuclear

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Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.

Browse to child terms:
Hepatocyte Nuclear Factor 4
Inositol 1,4,5-Trisphosphate Receptors
Liver X Receptors
Orphan Nuclear Receptors
Peroxisome Proliferator-Activated Receptors
Receptors for Activated C Kinase
Receptors, Artificial
Receptors, Calcitriol
Receptors, Melatonin
Receptors, Retinoic Acid
Receptors, Steroid
Receptors, Thyroid Hormone
Steroidogenic Factor 1

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jenkins-FCD Prod-388 89e904233d719332173309c68ab82b0b2a78a3a7