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Mesh term Immunophilins

Browse to parent terms:
Peptidylprolyl Isomerase
Receptors, Drug
Receptors, Immunologic

Description

Members of a family of highly conserved proteins which are all cis-trans peptidyl-prolyl isomerases (PEPTIDYLPROLYL ISOMERASE). They bind the immunosuppressant drugs CYCLOSPORINE; TACROLIMUS and SIROLIMUS. They possess rotamase activity, which is inhibited by the immunosuppressant drugs that bind to them.


Browse to child terms:
Cyclophilins
Tacrolimus Binding Proteins


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jenkins-FCD Prod-411 e00897e83867fcfa48419861683711f8d99adb75