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Mesh term MicroRNAs

Browse to parent terms:
RNA, Antisense
RNA, Small Untranslated

Description

Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing.


Browse to child terms:
Circulating MicroRNA


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View this term at the NCBI website
jenkins-FCD Prod-200 8231f2114cbb5b433e24eeafff71f933aa5694c5