Medical College of Wisconsin
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Mesh term Receptors, Tumor Necrosis Factor, Member 14

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Receptors, Tumor Necrosis Factor
Receptors, Virus

Description

A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.



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jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad