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Mesh term Agouti-Related Protein

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Intercellular Signaling Peptides and Proteins

Description

A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY.



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jenkins-FCD Prod-332 f92a19b0ec5e8e1eff783fac390ec127e367c2b5