Faculty Collaboration Database

Variability in immunization guidelines in children before and after lung transplantation. Pediatr Transplant 2007 Dec;11(8):882-7

Date

11/03/2007

Pubmed ID

17976123

DOI

10.1111/j.1399-3046.2007.00759.x

Scopus ID

2-s2.0-35748936144 (requires institutional sign-in at Scopus site)   32 Citations

Abstract

Lung transplant candidates and recipients are at high risk of infections from vaccine-preventable diseases. However, well-established guidelines neither exist for pre- and post-transplant vaccination nor do monitoring guidelines for pediatric lung transplant recipients. To ascertain the current vaccination and monitoring practices of pediatric lung transplant centers, a self-administered questionnaire was distributed to the 18 pediatric lung transplant centers within the International Pediatric Lung Transplant Collaborative in April 2006. Sixteen of 18 centers (89%) surveyed responded. Pretransplant, national vaccination guidelines are followed. Eleven centers reported following standardized vaccination guidelines post-transplant. Vaccines were more commonly provided by the primary-care physician pretransplant (69%) rather than post-transplant (38%). Post-transplant, 50% of the centers recommend live vaccines for household contacts but not for the transplant recipient. Pretransplant monitoring of response to prior vaccination was performed inconsistently except for varicella (88%). Only 44% of the transplant centers measure for response to vaccination post-transplant, mostly hepatitis B. Current vaccination practices of pediatric lung transplant centers are heterogeneous. The lung transplant community would be well served by studies designed to evaluate the efficacy of vaccinations in this population.

Author List

Benden C, Danziger-Isakov LA, Astor T, Aurora P, Bluemchen K, Boyer D, Conrad C, Eichler I, Elidemir O, Goldfarb S, Michaels MG, Mogayzel PJ, Mueller C, Parakininkas D, Oberkfell D, Solomon M, Boehler A

Author

Daiva E. Parakininkas MD Associate Professor in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Canada
Child
Europe
Follow-Up Studies
Humans
Incidence
Infection Control
Lung Transplantation
Postoperative Care
Postoperative Complications
Practice Guidelines as Topic
Preoperative Care
Respiratory Insufficiency
Retrospective Studies
Surveys and Questionnaires
United States
Vaccination
Vaccines