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Successful management of epithelial ingrowth after sequential intracameral 5-fluorouracil and Descemet-stripping automated endothelial keratoplasty. J Cataract Refract Surg 2019 05;45(5):690-693

Date

03/12/2019

Pubmed ID

30853320

DOI

10.1016/j.jcrs.2018.12.030

Scopus ID

2-s2.0-85062388761

Abstract

To describe the successful treatment of epithelial ingrowth using combined surgical excision with intracameral adjuvant 5-fluorouracil (5-FU) followed by Descemet-stripping automated endothelial keratoplasty (DSAEK). A 71-year-old man presented with epithelial ingrowth after clear corneal phacoemulsification. He underwent surgical excision of the membrane together with pars plana vitrectomy, air fluid exchange, and intracameral 5-FU. This treatment resulted in corneal decompensation for which DSAEK was performed 6 months later. Despite interface haze, the postoperative corrected distance visual acuity returned to 20/40 three months after DSAEK. There was no clinical evidence of recurrence of the epithelial ingrowth 9 months after the surgical removal. Intracameral 5-FU can be used in conjunction with surgical excision and subsequent DSAEK to successfully treat epithelial ingrowth.

Author List

Koenig SB, Koenig LR, Connor TB, Simons KB

Authors

Thomas B. Connor MD Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin
Kenneth B. Simons MD Sr Associate Dean, Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Aged
Anterior Chamber
Antimetabolites
Combined Modality Therapy
Cornea
Corneal Diseases
Descemet Stripping Endothelial Keratoplasty
Epithelium, Corneal
Fluorouracil
Humans
Male
Phacoemulsification
Slit Lamp Microscopy