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A Comparative in vivo Study of Semi-constrained and Unconstrained Cervical Artificial Disc Prostheses. Mil Med 2019 Mar 01;184(Suppl 1):637-643

Date

03/23/2019

Pubmed ID

30901460

DOI

10.1093/milmed/usy395

Scopus ID

2-s2.0-85063695268 (requires institutional sign-in at Scopus site)   19 Citations

Abstract

PURPOSE: The objective of this study is to directly compare different types of cervical artificial disc implants using an in vivo model capable of simulating the axial load on a neck that is similar to the human neck.

METHODS: Cervical arthroplasty was performed at C3-4 in 14 healthy female adult Alpine goats. The goats were divided into three groups. Group A received Bryan (unconstrained one-piece design); Group B received ProDisc-C (semi-constrained two-piece design); and Group C received Mobi-C (unconstrained three-piece design) artificial discs. The goats were monitored in a veterinary unit for 6 months with radiography at regular intervals.

RESULTS: Each goat tolerated cervical arthroplasty well and had satisfactory placement of their implant per intra-operative radiography. Implants monitored in Group A demonstrated no migration. One out of five implants in Group B experienced anterior migration at 3 months. In Group C, anterior migration and disintegration occurred in all four implants, with migration occurring during the first postoperative week in three implants and after 5 weeks in the fourth.

CONCLUSIONS: Unconstrained multi-piece artificial cervical discs may be prone to anterior migration and extrusion out of the disc space. This outcome deserves attention in individuals with a hypermobile neck and/or an occupation involving the use of a head-supported mass, such as helmets.

Author List

Choi H, Baisden JL, Yoganandan N

Author

Narayan Yoganandan PhD Professor in the Neurosurgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Biomechanical Phenomena
Cervical Vertebrae
Disease Models, Animal
Goats
Prosthesis Design
Range of Motion, Articular
Spinal Fusion
Total Disc Replacement