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Effects of cholecystokinin octapeptide and hydrocortisone on the development of fetal rat pancreas. Biol Neonate 1983;44(5):287-94

Date

01/01/1983

Pubmed ID

6196058

DOI

10.1159/000241729

Scopus ID

2-s2.0-0020599729 (requires institutional sign-in at Scopus site)   9 Citations

Abstract

Mechanisms and development of pancreas and pancreatic secretory function were studied in the rat. Injections of cholecystokinin octapeptide and hydrocortisone into pregnant rats altered pancreatic size, zymogen enzyme, and DNA content in the fetal newborn pancreas. These studies suggest that the developmental signals for pancreatic function may be related to endogenous release of cholecystokinin or hydrocortisone in the perinatal period.

Author List

Werlin SL, Stefaniak J

Author

Steven L. Werlin MD Emeritus Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Amylases
Animals
DNA
Female
Fetus
Hydrocortisone
Pancreas
Pregnancy
Rats
Sincalide