Faculty Collaboration Database

Diabetes and rheumatic diseases. Curr Opin Rheumatol 2009 Jan;21(1):50-4

Date

12/17/2008

Pubmed ID

19077719

DOI

10.1097/BOR.0b013e32831bc0c4

Scopus ID

2-s2.0-58149236804 (requires institutional sign-in at Scopus site)   85 Citations

Abstract

PURPOSE OF REVIEW: This review summarizes recent advances in the field of diabetes and rheumatic disease. These conditions exert a significant healthcare burden on our society and much remains to be learned regarding their pathophysiology and treatment.

RECENT FINDINGS: We summarize new insights into diabetes and its association with osteoarthritis, rheumatoid arthritis, carpal tunnel syndrome, osteoporosis, diffuse idiopathic skeletal hyperostosis, crystalline arthropathy, neuropathic arthropathy, and tendinopathy. Diabetes has major effects on connective tissues, which have significant impact on both the development and outcome of these diseases of cartilage, bone, ligament, and tendon. An improved understanding of the mechanisms through which diabetes alters connective tissue metabolism should lead to better preventive and therapeutic interventions.

SUMMARY: Incremental progress has been made in understanding the interactions between diabetes and common musculoskeletal syndromes. Although this review highlights exciting areas of future interest, more work in this field is certainly warranted.

Author List

Burner TW, Rosenthal AK

Authors

Todd W. Burner MD Assistant Professor in the Medicine department at Medical College of Wisconsin
Ann K. Rosenthal MD Associate Dean, Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Arthritis
Cartilage
Connective Tissue
Diabetes Complications
Gout
Humans
Hyperostosis
Rheumatic Diseases
Tendinopathy
Tendons