Evaluation and management of the infant exposed to HIV-1 in the United States. Pediatrics 2009 Jan;123(1):175-87
Date
01/02/2009Pubmed ID
19117880DOI
10.1542/peds.2008-3076Scopus ID
2-s2.0-59449102728 (requires institutional sign-in at Scopus site) 37 CitationsAbstract
The pediatrician plays a key role in the prevention of mother-to-child transmission of HIV-1 infection. For infants born to women with HIV-1 infection identified during pregnancy, the pediatrician ensures that antiretroviral prophylaxis is provided to the infant to decrease the risk of acquiring HIV-1 infection and promotes avoidance of postnatal HIV-1 transmission by advising HIV-1-infected women not to breastfeed. The pediatrician should perform HIV-1 antibody testing for infants born to women whose HIV-1 infection status was not determined during pregnancy or labor. For HIV-1-exposed infants, the pediatrician monitors the infant for early determination of HIV-1 infection status and for possible short- and long-term toxicity from antiretroviral exposures. Provision of chemoprophylaxis for Pneumocystis jiroveci pneumonia and support of families living with HIV-1 by providing counseling to parents or caregivers are also important components of care.
Author List
Havens PL, Mofenson LM, American Academy of Pediatrics Committee on Pediatric AIDSMESH terms used to index this publication - Major topics in bold
Anti-Retroviral AgentsAntiretroviral Therapy, Highly Active
Disease Management
Female
HIV Infections
HIV-1
Humans
Infant
Infectious Disease Transmission, Vertical
Pregnancy
Pregnancy Complications, Infectious
United States