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Rabies-prevention policy update: new reduced-dose schedule. Pediatrics 2011 Apr;127(4):785-7

Date

03/30/2011

Pubmed ID

21444598

DOI

10.1542/peds.2011-0095

Scopus ID

2-s2.0-79953305464   8 Citations

Abstract

The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention recommends reducing the number of doses from 5 to 4 of human diploid cell vaccine or purified chick embryo cell vaccine required for postexposure prophylaxis to prevent rabies in humans. The vaccine doses should be given on day 0 (first day of prophylaxis) and days 3, 7, and 14 after the first dose. For persons with immune suppression, the 5-dose regimen should continue to be used. Recommendations for the use of human rabies immunoglobulin remain unchanged. The American Academy of Pediatrics endorses these recommendations.

Author List

Committee on Infectious Diseases

Author

Rodney E. Willoughby MD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Child
Dose-Response Relationship, Drug
Guideline Adherence
Humans
Immune Tolerance
Immunization, Passive
Immunization, Secondary
Rabies
Rabies Vaccines