Epidemiology, diagnosis, prevention and treatment of catheter-related thrombosis in children and adults. Thromb Res 2017 Sep;157:64-71
Date
07/16/2017Pubmed ID
28710972DOI
10.1016/j.thromres.2017.07.002Scopus ID
2-s2.0-85021923944 (requires institutional sign-in at Scopus site) 56 CitationsAbstract
In this narrative review, the epidemiology, diagnosis, prevention strategies, and management of catheter-related thrombosis are outlined. Central venous catheters have significantly improved the quality of life of patients requiring chemotherapy, parenteral nutrition, and chronic transfusions. Catheter-related thrombosis (CRT) complicates between 1-5% of inserted catheters, with incidence varying between patient population, catheter type, and vein cannulated. Strategies to prevent CRT, including anticoagulation and locking solutions, have largely been ineffective. Using clinical decision tools and D-dimer testing can limit radiographic testing for patients with suspected CRT. Although most patients with CRT are treated with anticoagulation, the most effective type and duration of treatment have not been established for adults or children. Many unanswered questions remain concerning risk stratification, prevention, and management of CRT. National and international collaborative research networks could be harnessed to perform these much needed studies.
Author List
Baumann Kreuziger L, Jaffray J, Carrier MAuthor
Lisa M. Baumann Kreuziger MD Associate Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultCentral Venous Catheters
Child
Child, Preschool
Female
Humans
Male
Quality of Life
Risk Factors
Upper Extremity Deep Vein Thrombosis
Young Adult