CD5 negative mantle cell lymphoma: a different clinical entity? Conn Med 2014 Apr;78(4):211-4
Date
05/17/2014Pubmed ID
24830117Scopus ID
2-s2.0-84901467611 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
We report herein a 77-year-old patient with CD5 negative mantle cell lymphoma (MCL). We further review the existing literature on clinicolaboratory features of this rare MCL subtype. Although most of the patients in the literature (including ours) had advanced stage at diagnosis, splenomegaly, and bone marrow involvement, they displayed prompt and durable responses to conventional treatment. We postulate that CD5 surface antigen expression could have prognostic implications in MCL. Further research and a larger number of patients are necessary in order to validate these findings.
Author List
Alvarez-Argote J, Bauer FA, Dasanu CAAuthor
Juliana Alvarez Argote MD Assistant Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedCD5 Antigens
Cyclin D1
Female
Genes, bcl-1
Humans
Lymphoma, Mantle-Cell