Medical College of Wisconsin
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Gaucher disease: successful treatment of myoclonic status epilepticus with levetiracetam. Epileptic Disord 2012 Jun;14(2):155-8

Date

05/10/2012

Pubmed ID

22569507

DOI

10.1684/epd.2012.0501

Scopus ID

2-s2.0-84864541447 (requires institutional sign-in at Scopus site)   8 Citations

Abstract

We present the first reported case of a rapid clinical and electroencephalographic response to intravenous levetiracetam infusion of myoclonic status epilepticus in a patient with progressive myoclonus epilepsy due to Gaucher disease. Under continuous video-EEG monitoring, the clinical myoclonic status and the electrographic ictal discharges resolved within 10 minutes after the infusion was initiated. The patient tolerated the treatment well without any reported side effects. This case suggests that levetiracetam may be a safe, effective, and well tolerated intravenous drug in patients with metabolic myoclonic status epilepticus such as Gaucher disease.

Author List

Vaca GF, Lenz T, Knight EM, Tuxhorn I

Author

Timothy John Lenz MD Associate Professor in the Emergency Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Anticonvulsants
Electroencephalography
Epilepsies, Myoclonic
Gaucher Disease
Humans
Male
Piracetam
Status Epilepticus