The prevalence of cholelithiasis in sickle cell disease as diagnosed by ultrasound and cholecystography. Pediatrics 1979 Nov;64(5):601-3
Date
11/01/1979Pubmed ID
492833Scopus ID
2-s2.0-0018717574 (requires institutional sign-in at Scopus site) 99 CitationsAbstract
Gallbladder disease is known to be increased in sickle cell disease (SS). The prevalence of cholelithiasis in children with SS has been reported as 10% to 37%. Gallbladder ultrasound, cholecystography, and/or abdominal radiography were used to evaluate 31 patients aged 2 to 18 years with no systematic evidence of gallbladder disease for cholelithiasis, Overall prevalence of gallstones was found to be 29%. Cholelithiasis was detected in children as young as 4 years of age. Prevalence below the age of 10 years and above the age of 10 years was found to be 11% and 55% respectively. The increased prevalence of cholelithiasis in children with sickle cell disease suggests the use of diagnostic ultrasonography as a routine screening procedure.
Author List
Lachman BS, Lazerson J, Starshak RJ, Vaughters FM, Werlin SLAuthor
Steven L. Werlin MD Emeritus Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAnemia, Sickle Cell
Child
Child, Preschool
Cholangiography
Cholecystography
Cholelithiasis
Erythrocyte Count
Hemoglobins
Humans
Reticulocytes
Ultrasonography
