Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

The Role of Ablation in Cancer Pain Relief. Curr Oncol Rep 2019 11 25;21(12):105



Pubmed ID




Scopus ID



PURPOSE OF REVIEW: The purpose of this article is to describe the concepts of ablation techniques for pain relief in symptomatic oncologic patients. Controversies concerning techniques and products will be addressed.

RECENT FINDINGS: Despite conventional pain palliative techniques, cancer patients often endorse unresolved somatic and neuropathic pain that can present as a great burden to quality of life. In non-operative patients, several techniques have been applied to minimize opioid dependence. While radiotherapy is often considered as a non-invasive option, percutaneous ablation has been advanced as a minimally-invasive alternative with clear procedural and outcome advantages. Similar to radiation therapy, percutaneous ablation techniques can act either upon nerve structures responsible for pain mediation signals (neurolysis) or directly upon the tumor to relieve tumor-mediated inflammation and decompress tumor compression of adjacent structures. Percutaneous ablation provides valuable neurolysis and tumor-directed pain palliative effects to be incorporated into clinical guidelines for pain reduction in oncologic patients. Selection among different ablation techniques should be based upon an individually tailored approach, to include consideration of all treatment modalities.

Author List

Filippiadis DK, Yevich S, Deschamps F, Jennings JW, Tutton S, Kelekis A


Sean Tutton MD Vice Chair, Professor in the Radiology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Ablation Techniques
Cancer Pain
Pain Management
jenkins-FCD Prod-480 9a4deaf152b0b06dd18151814fff2e18f6c05280