Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Generalized simultaneous multi-orientation 2D imaging. Magn Reson Med 2020 08;84(2):847-856



Pubmed ID




Scopus ID



PURPOSE: Flexibility in slice prescription is critical for precise motion monitoring during MR-guided therapies. Adding more slices to improve spatial coverage during rapid 2D cine imaging often hampers temporal resolution. This work describes a framework to simultaneously acquire multiple arbitrarily oriented slices which share a common frequency encoding axis. This framework allows for higher frame rates for a given number of slices compared to conventional interleaved-slice multi-orientation cine imaging.

THEORY AND METHODS: A framework to calculate zeroth gradient moments to be played out between sequentially excited slices with multiple orientations is described here. Experiments were performed in phantom, and in vivo in the head/neck and abdomen of patients.

RESULTS: Images arbitrarily rotated relative to one another were successfully obtained in phantom and in vivo. Simultaneous multi-orientation (SMO) images were also acquired with additional in-plane acceleration to demonstrate the capability of this method to rapidly image objects moving with physiological motion.

CONCLUSIONS: The technical feasibility of the generalized SMO imaging framework was tested in this study. It shows promise for continued development for motion monitoring during MR-guided therapies.

Author List

Mickevicius NJ, Nencka AS, Paulson ES


Nikolai J. Mickevicius PhD Assistant Professor in the Radiology department at Medical College of Wisconsin
Andrew S. Nencka PhD Director, Associate Professor in the Radiology department at Medical College of Wisconsin
Eric Paulson PhD Associate Professor in the Radiation Oncology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Image Interpretation, Computer-Assisted
Image Processing, Computer-Assisted
Imaging, Three-Dimensional
Magnetic Resonance Imaging
Phantoms, Imaging