Platelet α-granules contribute to organ-specific pathologies in a mouse model of severe malaria. Blood Adv 2020 Jan 14;4(1):1-8
Date
01/01/2020Pubmed ID
31891656Pubmed Central ID
PMC6960474DOI
10.1182/bloodadvances.2019000773Scopus ID
2-s2.0-85078185569 (requires institutional sign-in at Scopus site) 9 CitationsAbstract
Nbeal2 deficiency leads to significantly reduced lung and brain pathology and enhanced survival in a mouse model of malaria. Both antibody-dependent and antibody-independent platelet depletion in mice recapitulate the findings observed in Nbeal2−/− mice.
Author List
Darling TK, Schenk MP, Zhou CC, Maloba FM, Mimche PN, Gibbins JM, Jobe SM, Lamb TJMESH terms used to index this publication - Major topics in bold
AnimalsBlood Platelets
Cytoplasmic Granules
Disease Models, Animal
Malaria
Mice
