Pneumoconiosis in workers exposed to silicon carbide. Am Rev Respir Dis 1984 Apr;129(4):635-40
Date
04/01/1984Pubmed ID
6712005Scopus ID
2-s2.0-0021248981 (requires institutional sign-in at Scopus site) 35 CitationsAbstract
Two men who had been exposed only to silicon carbide for many years in a factory manufacturing refractory bricks developed bilateral reticulonodular densities, as shown on chest radiograms, and complained of dyspnea. An open lung biopsy of one of them showed a large amount of black material in the fibrosed alveolar septums. Studies by X-ray diffraction revealed that the silicon carbide to which they were exposed did not contain quartz; X-ray powder diffraction analysis of the lung tissue revealed at least 6 different silicon carbides, traces of tungsten carbide, and an insignificant amount of quartz. Line-width analysis of the pattern suggested that the lung contained foreign material, with a significant number of particles smaller than 0.1 micron. The etiologic role of silicon carbide for tissue fibrosis is discussed.
Author List
Funahashi A, Schlueter DP, Pintar K, Siegesmund KA, Mandel GS, Mandel NSAuthor
Neil S. Mandel PhD Emeritus Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAir Pollutants, Occupational
Carbon
Carbon Compounds, Inorganic
Humans
Lung
Male
Middle Aged
Pneumoconiosis
Radiography
Silicon
Silicon Compounds
