The influence of ion species on phosphatidylcholine bilayer structure and packing. Chem Phys Lipids 1986 Jan;39(1-2):135-43
Date
01/01/1986Pubmed ID
3753902DOI
10.1016/0009-3084(86)90107-6Scopus ID
2-s2.0-0022630332 (requires institutional sign-in at Scopus site) 44 CitationsAbstract
The effects of various monovalent cations and anions on the bilayer packing and structure of dipalmitoylphosphatidylcholine were studied using X-ray diffraction and differential scanning calorimetry. It was observed from the X-ray diffraction studies that monovalent salts, in general, have no effect on bilayer packing. The results of DSC studies on metal chloride systems are consistent with the interpretation that cations in general and Li+ in particular bind to DPPC bilayers. The effect of potassium salts on pre- and main-transition temperatures suggest that anions, such as Acetate-, also significantly bind to DPPC head groups.
Author List
Cunningham BA, Shimotake JE, Tamura-Lis W, Mastran T, Kwok WM, Kauffman JW, Lis LJAuthor
Wai-Meng Kwok PhD Professor in the Anesthesiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnionsCations, Monovalent
Gels
Lipid Bilayers
Models, Biological
Molecular Conformation
Pulmonary Surfactants
Thermodynamics
X-Ray Diffraction
