Update on Pheochromocytoma and Paraganglioma from the SSO Endocrine/Head and Neck Disease-Site Work Group. Part 1 of 2: Advances in Pathogenesis and Diagnosis of Pheochromocytoma and Paraganglioma. Ann Surg Oncol 2020 May;27(5):1329-1337
Date
03/01/2020Pubmed ID
32112212Pubmed Central ID
PMC8655649DOI
10.1245/s10434-020-08220-3Scopus ID
2-s2.0-85081369267 (requires institutional sign-in at Scopus site) 51 CitationsAbstract
This first part of a two-part review of pheochromocytoma and paragangliomas (PPGLs) addresses clinical presentation, diagnosis, management, treatment, and outcomes. In this first part, the epidemiology, prevalence, genetic etiology, clinical presentation, and biochemical and radiologic workup are discussed. In particular, recent advances in the genetics underlying PPGLs and the recommendation for genetic testing of all patients with PPGL are emphasized. Finally, the newer imaging methods for evaluating of PPGLs are discussed and highlighted.
Author List
Patel D, Phay JE, Yen TWF, Dickson PV, Wang TS, Garcia R, Yang AD, Solórzano CC, Kim LTAuthors
Tracy S. Wang MD, MPH Professor in the Surgery department at Medical College of WisconsinTina W F Yen MD, MS Professor in the Surgery department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AbdomenAdrenal Gland Neoplasms
Arrhythmias, Cardiac
Catecholamines
Chromaffin Cells
Ganglia, Parasympathetic
Ganglia, Sympathetic
Genetic Testing
Headache
Humans
Hypertension
Multiple Endocrine Neoplasia Type 2a
Multiple Endocrine Neoplasia Type 2b
Neoplastic Syndromes, Hereditary
Neurofibromatosis 1
Paraganglioma
Paraganglioma, Extra-Adrenal
Pelvis
Pheochromocytoma
Sweating
von Hippel-Lindau Disease
