Contraceptive compliance with a levonorgestrel triphasic and a norethindrone monophasic oral contraceptive in adolescent patients. Am J Obstet Gynecol 1992 Mar;166(3):901-7
Date
03/01/1992Pubmed ID
1550161DOI
10.1016/0002-9378(92)91359-iScopus ID
2-s2.0-0026607740 (requires institutional sign-in at Scopus site) 21 CitationsAbstract
OBJECTIVE: This study was undertaken to assess the impact of two low-dose oral contraceptive pills on compliance and side effects in adolescent patients.
STUDY DESIGN: The use of a levonorgestrel-containing triphasic pill (N = 114) was compared with that of a monophasic (1 + 35) norethindrone-containing pill (N = 110) at two different sociodemographic sites.
RESULTS: No significant difference in compliance or pill satisfaction was observed between the pills. Socioeconomic factors were the overriding predictors of compliance. At 3 and 12 months of follow-up, there were significantly fewer complaints of overall side effects (p less than 0.001 and p = 0.004, respectively), breakthrough bleeding (p = 0.017 and p = 0.018), and pill amenorrhea (p = 0.002 and p less than 0.001) among users of the triphasic pill. Mean weight change at 12 months was +1.1 kg for the monophasic pill and -0.1 kg for the triphasic pill. All known pregnancies occurred among noncompliant city clinic patients.
CONCLUSIONS: Adolescents experienced fewer side effects with the triphasic pill than with the monophasic one, but compliance was the same.
Author List
Woods ER, Grace E, Havens KK, Merola JL, Emans SJMESH terms used to index this publication - Major topics in bold
AdolescentContraceptives, Oral
Female
Follow-Up Studies
Humans
Levonorgestrel
Norethindrone
Patient Compliance
Regression Analysis
Suburban Population
Urban Population