Congenital hypertrophic pyloric stenosis: the role of gastrin reevaluated. Pediatrics 1978 Jun;61(6):883-5
Date
06/01/1978Pubmed ID
673551Scopus ID
2-s2.0-0017822863 (requires institutional sign-in at Scopus site) 10 CitationsAbstract
In order to evaluate the potential role of gastrin in the etiology of pyloric stenosis, serum gastrin levels were measured in cord blood of affected infants, matched controls, and mothers of both. No differences were identified when values from infants with pyloric stenosis were compared with those from control infants. Mean cord serum gastrin levels of the infants were significantly greater than the mean maternal gastrin levels. The data effectively dismiss the possibility that elevated serum gastrin concentration in mother or infant at the time of delivery can be implicated as a cause of pyloric stenosis.
Author List
Werlin SL, Grand RJ, Drum DEAuthor
Steven L. Werlin MD Emeritus Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Fetal BloodGastrins
Humans
Hypertrophy
Infant, Newborn
Pyloric Stenosis
