Complete and durable response of choroid metastasis from non-small cell lung cancer with systemic bevacizumab and chemotherapy. J Thorac Oncol 2009 May;4(5):661-2
Date
04/28/2009Pubmed ID
19395911DOI
10.1097/JTO.0b013e31819c9a73Scopus ID
2-s2.0-67651159238 (requires institutional sign-in at Scopus site) 35 CitationsAbstract
Ocular metastasis from lung cancer is uncommon. We report a patient with metastatic non-small cell lung cancer who was found to have a metastatic lesion in the choroid at the time of presentation. The patient was treated with carboplatin, gemcitabine, and bevacizumab. After three cycles of chemotherapy, radiologic imaging and ophthalmologic examination demonstrated complete resolution of the choroid lesion. This case report demonstrates the durable response of choroidal metastasis from non-small cell lung cancer to systemic bevacizumab and chemotherapy.
Author List
George B, Wirostko WJ, Connor TB, Choong NWAuthors
Thomas B. Connor MD Professor in the Ophthalmology and Visual Sciences department at Medical College of WisconsinBen George MD Professor in the Medicine department at Medical College of Wisconsin
William Wirostko MD Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdultAntibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Antineoplastic Combined Chemotherapy Protocols
Bevacizumab
Carboplatin
Carcinoma, Non-Small-Cell Lung
Choroid Neoplasms
Deoxycytidine
Female
Humans
Lung Neoplasms
Prognosis
Treatment Outcome