Medical College of Wisconsin
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Mechanisms of gastroesophageal reflux in children. J Pediatr 1980 Aug;97(2):244-9

Date

08/01/1980

Pubmed ID

7400890

DOI

10.1016/s0022-3476(80)80482-3

Scopus ID

2-s2.0-0018889578 (requires institutional sign-in at Scopus site)   165 Citations

Abstract

We studied the lower esophageal sphincter in 29 children with known or suspected gastroesophageal reflux using a sleeve sensor and micro pH electrode. Mean lower esophageal sphincter pressure for a ten-minute monitoring period was 19 +/- 13 mm Hg; however, considerable temporal variation occurred in each child. Gastroesophageal reflex was infrequently associated with a low basal sphincter pressure (< 5 mm Hg) but usually associated with an increase in intra-abdominal pressure or with transient inappropriate relaxation of the lower esophageal sphincter.

Author List

Werlin SL, Dodds WJ, Hogan WJ, Arndorfer RC

Author

Steven L. Werlin MD Emeritus Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Child, Preschool
Esophagus
Gastroesophageal Reflux
Humans
Infant
Infant, Newborn
Muscle Relaxation
Pressure