Secondary hypertension in overweight and stage 1 hypertensive children: a Midwest Pediatric Nephrology Consortium report. J Clin Hypertens (Greenwich) 2010 Jan;12(1):34-9
Date
01/06/2010Pubmed ID
20047628Pubmed Central ID
PMC8672976DOI
10.1111/j.1751-7176.2009.00195.xScopus ID
2-s2.0-77949350061 (requires institutional sign-in at Scopus site) 58 CitationsAbstract
According to the Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents, stage 1 hypertension is often primary in origin and associated with overweight. In contrast, stage 2 hypertension is more often secondary in origin and, hence, requires more extensive evaluation according to task force recommendations. The objective of this retrospective study was to evaluate whether the presence of stage 1 hypertension in overweight pediatric patients precludes workup for secondary hypertension (SH). This study included children (5-18 years) with hypertension (defined and staged per task force recommendations) referred to 4 pediatric nephrology centers in the Midwest region. Of the 246 referred patients, 166 patients with primary hypertension (PH) and SH were included for body mass index and hypertension stage analysis. The study revealed no significant differences in the mean age at diagnosis (PH, 13.1+/-3.1 years; SH, 12.4+/-3.8 years), distribution of overweight (PH, 89.4% BMI >85th percentile; SH, 80% BMI >85th percentile), and stage 1 (PH, 45%; SH, 40%) or 2 hypertensive (PH,55%; SH, 60%) children between PH vs SH. Overweight and presence of stage 1 hypertension should not preclude evaluation for SH.
Author List
Kapur G, Ahmed M, Pan C, Mitsnefes M, Chiang M, Mattoo TKAuthor
Cynthia G. Pan MD Adjunct Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentBody Mass Index
Child
Child, Preschool
Female
Humans
Hypertension
Male
Overweight
Retrospective Studies
Severity of Illness Index