Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Secondary hypertension in overweight and stage 1 hypertensive children: a Midwest Pediatric Nephrology Consortium report. J Clin Hypertens (Greenwich) 2010 Jan;12(1):34-9

Date

01/06/2010

Pubmed ID

20047628

Pubmed Central ID

PMC8672976

DOI

10.1111/j.1751-7176.2009.00195.x

Scopus ID

2-s2.0-77949350061 (requires institutional sign-in at Scopus site)   58 Citations

Abstract

According to the Fourth Report on the Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and Adolescents, stage 1 hypertension is often primary in origin and associated with overweight. In contrast, stage 2 hypertension is more often secondary in origin and, hence, requires more extensive evaluation according to task force recommendations. The objective of this retrospective study was to evaluate whether the presence of stage 1 hypertension in overweight pediatric patients precludes workup for secondary hypertension (SH). This study included children (5-18 years) with hypertension (defined and staged per task force recommendations) referred to 4 pediatric nephrology centers in the Midwest region. Of the 246 referred patients, 166 patients with primary hypertension (PH) and SH were included for body mass index and hypertension stage analysis. The study revealed no significant differences in the mean age at diagnosis (PH, 13.1+/-3.1 years; SH, 12.4+/-3.8 years), distribution of overweight (PH, 89.4% BMI >85th percentile; SH, 80% BMI >85th percentile), and stage 1 (PH, 45%; SH, 40%) or 2 hypertensive (PH,55%; SH, 60%) children between PH vs SH. Overweight and presence of stage 1 hypertension should not preclude evaluation for SH.

Author List

Kapur G, Ahmed M, Pan C, Mitsnefes M, Chiang M, Mattoo TK

Author

Cynthia G. Pan MD Adjunct Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Body Mass Index
Child
Child, Preschool
Female
Humans
Hypertension
Male
Overweight
Retrospective Studies
Severity of Illness Index