Patient-Centric Head and Neck Cancer Radiation Therapy: Role of Advanced Imaging. Neuroimaging Clin N Am 2020 Aug;30(3):341-357
Date
07/01/2020Pubmed ID
32600635DOI
10.1016/j.nic.2020.04.005Scopus ID
2-s2.0-85086387343 (requires institutional sign-in at Scopus site) 1 CitationAbstract
The traditional 'one-size-fits-all' approach to H&N cancer therapy is archaic. Advanced imaging can identify radioresistant areas by using biomarkers that detect tumor hypoxia, hypercellularity etc. Highly conformal radiotherapy can target resistant areas with precision. The critical information that can be gleaned about tumor biology from these advanced imaging modalities facilitates individualized radiotherapy. The tumor imaging world is pushing its boundaries. Molecular imaging can now detect protein expression and genotypic variations across tumors that can be exploited for tailoring treatment. The exploding field of radiomics and radiogenomics extracts quantitative, biologic and genetic information and further expands the scope of personalized therapy.
Author List
Shukla M, Forghani R, Agarwal MAuthor
Monica E. Shukla MD Associate Professor in the Radiation Oncology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Diagnostic ImagingHead and Neck Neoplasms
Humans
Radiotherapy Planning, Computer-Assisted
Radiotherapy, Conformal
