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Leukocyte hexokinase activity in aging and Alzheimer disease. Dementia 1995;6(4):200-4

Date

07/01/1995

Pubmed ID

7550599

DOI

10.1159/000106947

Scopus ID

2-s2.0-0029018903 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

We determined the effects of clinical variables on hexokinase (HK) activity in leukocytes from Alzheimer's disease (AD) patients and controls. Age accounted for 51% of the variance in HK activity in the young and 23% in the old. Duration of illness in both familial and sporadic AD accounted for HK levels by 32 and 38%, respectively. Hexokinase activity increases with age and does not discriminate between familial and sporadic AD.

Author List

Antuono PG, Ravanelli-Meyer J, Nicholson K, Bloom AS

Author

Piero G. Antuono MD Professor in the Neurology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Age Factors
Aged
Aging
Alzheimer Disease
Energy Metabolism
Family
Hexokinase
Humans
Leukocytes
Middle Aged