Infection prophylaxis patterns following pediatric autologous hematopoietic stem cell transplantation: A survey of Pediatric Transplant and Cell Therapy Consortium centers. Pediatr Transplant 2020 Dec;24(8):e13821
Date
08/28/2020Pubmed ID
32844543DOI
10.1111/petr.13821Scopus ID
2-s2.0-85089827784 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
No standardized guidelines exist for infectious prophylaxis following pediatric auto-HSCT. We hypothesized significant variation in clinical practice. Thirty-three Pediatric Transplant and Cell Therapy Consortium centers completed a survey to assess institutional management. The majority utilize viral (91%) and fungal prophylaxis (94%), but duration varies. Bacterial prophylaxis during neutropenia is instituted by 42%. Our study demonstrates marked practice variability in infectious prophylaxis across centers. Additional research is needed to address patterns of infectious complications and to develop meaningful clinical practice guidelines for pediatric auto-HSCT.
Author List
Falcon CP, Broglie L, Phelan R, Choi SW, Auletta JJ, Chewning JHAuthors
Larisa Broglie MD, MS Assistant Professor in the Pediatrics department at Medical College of WisconsinRachel A. Phelan MD, MPH Associate Professor in the Pediatrics department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
ChildDrug Resistance
Hematopoietic Stem Cell Transplantation
Humans
Postoperative Complications
Practice Patterns, Physicians'
Surveys and Questionnaires