Development and validation of osteoligamentous lumbar spine under complex loading conditions: A step towards patient-specific modeling. J Mech Behav Biomed Mater 2020 Oct;110:103898
Date
09/23/2020Pubmed ID
32957203DOI
10.1016/j.jmbbm.2020.103898Scopus ID
2-s2.0-85087592453 (requires institutional sign-in at Scopus site) 15 CitationsAbstract
Finite-element models are used to investigate the biomechanics of normal, diseased and surgically fused spines. Generally, nominal spine geometries are used to understand the biomechanics, which has created a need for a technique that develops patient-specific lumbar spine geometries. In the current study, a lumbar spine (T12-Sacrum) was developed using a technique that facilitates geometrical morphing, which assists in incorporating patient-specific morphologies into the model. The model evaluations can be used to propose a biomechanically suitable lumbar spine fusion procedure for patients. This study focuses on the validation of the base model under pure-moment, pure-compression and combined-compression-and-moment loadings. Experimental data from the literature were used to validate the response of the model. The L1-L2, L2-L3, L3-L4, L4-L5 and L5-sacrum segments demonstrated a range of motion of 4.5, 4.0, 5.4, 5.0 and 8.9° in flexion; 3.0, 2.5, 3.6, 3.1 and 5.2° in extension; 6.2, 5.8, 6.4, 5.0 and 6.1° in right and left lateral bending; and 2.9, 3.0, 2.9, 1.9 and 2.5° in right and left axial rotation, all under 10 Nm pure-moment loading. The L1-L2, L2-L3, L3-L4, L4-L5 and L5-sacrum discs demonstrated compressions of 1.1, 1.4, 1.6, 1.4 and 0.9 mm under 1200 N follower- or pure-compression loading. With the combined loading of 280 N follower and 7.5 Nm moment, the L1-L5 model demonstrated 11.7, 7.2, 18.3 and 10.4 degrees of range of motion in flexion, extension, bending and rotation, respectively. The model results were in good agreement with corridors from six different experimental studies and can be used for future clinical studies.
Author List
Umale S, Yoganandan N, Kurpad SNAuthors
Shekar N. Kurpad MD, PhD Sr Associate Dean, Professor in the Neurosurgery department at Medical College of WisconsinNarayan Yoganandan PhD Professor in the Neurosurgery department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Biomechanical PhenomenaHumans
Lumbar Vertebrae
Patient-Specific Modeling
Range of Motion, Articular
Spinal Fusion
