Stem Cell-Based Disease Modeling and Cell Therapy. Cells 2020 Sep 29;9(10)
Date
10/03/2020Pubmed ID
33003295Pubmed Central ID
PMC7599677DOI
10.3390/cells9102193Scopus ID
2-s2.0-85092490838 (requires institutional sign-in at Scopus site) 27 CitationsAbstract
Stem cell science is among the fastest moving fields in biology, with many highly promising directions for translatability. To centralize and contextualize some of the latest developments, this Special Issue presents state-of-the-art research of adult stem cells, induced pluripotent stem cells (iPSCs), and embryonic stem cells as well as cancer stem cells. The studies we include describe efficient differentiation protocols of generation of chondrocytes, adipocytes, and neurons, maturation of iPSC-derived cardiomyocytes and neurons, dynamic characterization of iPSC-derived 3D cerebral organoids, CRISPR/Cas9 genome editing, and non-viral minicircle vector-based gene modification of stem cells. Different applications of stem cells in disease modeling are described as well. This volume also highlights the most recent developments and applications of stem cells in basic science research and disease treatments.
Author List
Bai XMESH terms used to index this publication - Major topics in bold
CRISPR-Cas SystemsCell Differentiation
Cell- and Tissue-Based Therapy
Gene Editing
Humans
Induced Pluripotent Stem Cells
Neurons
Organoids
Stem Cell Research
